• Title/Summary/Keyword: 생리학적 변화

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Changes in Physiological Characteristics of Trapezius, Multifidus and Hamstring Muscles According to Tilt Angle of Exercise Bed in Elderly (운동침대 틸트 각도 변화에 따른 노인의 승모근, 다열근 및 슬괵근 근육의 생리학적 특성 변화 연속 증례 연구)

  • Kim, Jungjin
    • Archives of Orthopedic and Sports Physical Therapy
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    • v.14 no.2
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    • pp.127-133
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    • 2018
  • Purpose: This study investigated the effects of changing the tilt angle of the exercise bed on physiological characteristics of trapezius, multifidus, and hamstring muscle function. Methods: Twenty elderly who complains of back and lumbar pain or discomfort participated in this study (average age: $64.70{\pm}4.55$ years). The physiological characteristics, including muscle tone (F), dynamic stiffness (S), and elasticity (D) of trapezius, multifidus, and hamstring muscles were measured by a Myoton device at three tilt angles (0, 15, and 30 degrees) during exercise. Results: The muscle tone, dynamic stiffness, and elasticity of the right trapezius and left hamstring muscle showed significant differences (p<0.05) according to exercise bed tilt angle, while the other muscles showed no significant differences. Conclusions: Our results demonstrate that physiological characteristics of the upper and lower extremity muscles are affected ipsilaterally, according to the tilt angles of the exercise bed.

Anti-Inflammatory Effects of Poly-${\gamma}$-Glutamic Acid on DNCB-Induced Allergic Contact Dermatitis in Dogs (개에서 DNCB에 의해 유발된 알레르기성 접촉피부염에 대한 폴리감마글루탐산의 항염증 효과)

  • Kim, Hyun-Gon;Kim, Kil-Soo;Oh, Tae-Ho
    • Journal of Veterinary Clinics
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    • v.29 no.4
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    • pp.283-296
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    • 2012
  • Allergic contact dermatitis (ACD) is an inflammatory skin disease and regarded as a prototype of T-cell mediated delayed-type hypersensitivity reactions. Poly-${\gamma}$-glutamic acid (PGA) is a biodegradable polymer that is produced by Bacillus subtilis. This study was performed to assess the effects of PGA in a canine model of ACD. ACD was induced on the back of dogs induced by sensitization and repeated application by 2,4-dinitro-1-chlorobenzene (DNCB). Topical treatment of PGA was applied once a day for 12 days and skin biophysical parameters including transepidermal water loss (TEWL), skin hydration, skin pH, skin thickness and erythema index, were measured every two days during experimental periods. Histopathology and immunohistochemistry were performed to evaluate the antiinflammatory effect. In skin biophysical parameters, TEWL, skin hydration, skin thickness and erythema index were significantly increased, with a maximum increase appeared on day 2 (p < 0.05). On the other hand, skin pH was significantly decreased, with a maximum decrease appeared on day 2 (p < 0.01). After the completion of PGA treatment, skin biophysical parameters were significantly reached those of baseline in a time-dependent manner (p < 0.05). In histopathology, marked increases of epidermal thicknesses were induced after DNCB challenge with numerous inflammatory cell infiltrations and edematous changes, decreases of connective tissue occupied regions in dermis. In addition, marked increases of cytokine - tumor necrosis factor-${\alpha}$ (TNF-${\alpha}$) and interferon-${\gamma}$ (IFN-${\gamma}$)-immunoreactivities in the dermis and of apoptotic markers - caspase-3 and PARP-immunoreactivities in the epidermis were observed in DNCB-PBS control as compared with intact control, respectively (p < 0.01). It means, the ACD and related apoptotic changes were induced by DNCB in the present study. However, these ACD induced by DNCB and related apoptosis in epidermis were significantly inhibited by treatment of PGA treated skin, the decreases of infiltrated inflammatory cells and related decreases of pro-inflammatory cytokine immunoreactivities were also observed (p < 0.01). Based on these findings, PGA may have anti-inflammatory and alleviatory effects in the allergic contact dermatitis.

Evaluation of voice parameters following supracricoid laryngectomy

  • 김민식;조승호;박영학;선동일;김형태;유우정
    • Proceedings of the KSLP Conference
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    • 1997.11a
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    • pp.260-260
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    • 1997
  • 상윤상후두부분적출술은 과거 후두전적출술을 실시하던 환자들에서 선택적으로 사용하여 만족할만한 종양학적 결과 및 후두의 생리적인 기능을 보존 할 수 있어 점차 널리 보급되고. 있다. 이 술식후의 기능변화나 보상기전등에 대하여는 잘 알려지지 않았으나 정상인과 비교하여 음성지표들의 변화가 보고되고 있다. 이 수술은 원발병소의 위치에 따라 CHEP, CHP 방범으로 재건할 수 있으며 종양의 범위에 따라 일측의 피열연골과 윤상연골의 앞부분을 제거하는 extended procedure등이 사용되고 있다. (중략)

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심근섬유증의 정도에 따른 심실의 전기역학적 특성 분석

  • Lee, Ji-Yeong;Im, Gi-Mu
    • Proceeding of EDISON Challenge
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    • 2017.03a
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    • pp.653-655
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    • 2017
  • 심근섬유증은 심장에서 전도 장애를 일으키며 심부전증상을 발생시킨다. 심근섬유증으로 인한 심장박동현상의 변화를 확인하기 위해 시뮬레이션 연구를 진행하였다. 심실의 유한요소 모델을 설계하고 무작위로 전도 블록을 생성하여 심근섬유증을 적용하고 그 비율을 조절하였다. 심근섬유증의 비율에 따라 전기생리학적 시뮬레이션을 진행하고 그 결과를 바탕으로 기계 수축 시뮬레이션을 진행하여 심실의 수축 변화를 확인하였다. 심근섬유증의 비율이 증가할수록 좌심실의 압력이 감소하고 박출되는 혈액량과 박출계수, 심장박동의 효율이 감소하였다.

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Induction of Soft Tunic Syndrome by Water Temperature and Physiological and Histological Responses of the Sea Squirt, Halocynthia roretzi (수온에 의한 멍게(Halocynthia roretzi)의 물렁증 유도와 생리 및 조직학적 반응)

  • Shin, Yun Kyung;Park, Jung Jun;Myeong, Jeong In;Kim, Hyejin;Lee, Jung Sick
    • Korean Journal of Environmental Biology
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    • v.32 no.3
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    • pp.225-233
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    • 2014
  • In this study, we investigated the changes in the physiological and histological traits of a sea squirt (Halocynthia roretzi) with the emergence of the soft tunic syndrome induced by the water temperature control (6, 9, 12, 15, 18, 21, 24 and $27^{\circ}C$). It was observed that the induction rate of the soft tunic syndrome was highest at $15^{\circ}C$, but lowest at $24^{\circ}C$. Based on the tunic color condition and contraction strength, the whole process were classified into 4 stages as S0, S1, S2 and S3. Interestingly, there were significant differences in oxygen consumption and filtration rate were observed during S0-S3. The most distinctive aspects were change of blood cell composition at stage S3, whereas multi-vacuole cell ratio was decreased by 1/2 and morula cell ratio expanded about 10 times during S0-S3. Further, change of organ structure started following the syndrome such as degeneration of epithelial cells, microfilaments, increment in hemocytes and damage in muscle fiber have been detected in tunic, siphon, branchial sac, body wall musculature and pyloric gland. Briefly, our study results indicated that the normal physiological functions of the sea squirt can be affected due to the soft tunic syndrome induced by water temperature.

Ca2+ Uptake of the Sarcoplasmic Reticulum-Microsome of Fine Structure Pectoralis Major Muscle in the rabbit and the Korean Greater Horseshoe Bat* (토끼와 한국관박쥐 대흉근의 근소포체 마이크로솜의 Calcium Uptake에 관한 연구)

  • 오영근;양원석
    • The Korean Journal of Zoology
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    • v.38 no.1
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    • pp.10-19
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    • 1995
  • 동면동물인 한국관박쥐(Korean greater horseshoe bat)와 비롱면 롱물인 토끼의 근소포체가 지니는 생리 및 근조직의 형태적 특징을 비교해 보고자 본 실험을 수행하여 다음과 같은 결론을 내렸다 Caffeine과 Mgcl2는 농도별로 처리하고, p연와 온도에 변화를 주는 등 각각의 생리조건하에서 한국관박쥐와 토끼 대흉근 근소포체 마이크로솜의 C32' 흡수정도가 다르게 나타났으며, Ca2'ATPase 활성 역시 상이함을 보였는데. 이로 미루어 보아 in vivo 상태에서 두 동물의 근소포체가 지니는 생리적 특성에 차이가 있을 것으로 추측된다. 형태학적 측면에서도 근심유의 수기와 미토콘드리아의 크기에 있어서 뚜렷한 차이를 발견할 수 있었는데. 이는 두 동물의 대흉근이 수행하는 운동의 종류와 관련이 있을 것으로 생각된다.

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Effects of low salinity stresses on the physiology of disc abalone, Haliotis discus discus (저염분 자극에 의한 둥근전복, Haliotis discus discus의 생리학적 변화)

  • Jwa, Min-Seok;Kang, Kyung-pil;Choi, Mi-Kyung;Yeo, In-Kyu
    • Journal of fish pathology
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    • v.22 no.3
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    • pp.293-303
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    • 2009
  • Effects of stress on the low salinity stress were examined in the pacific abalone Haliotis discus discus. Changes in survival rate, hemolymph count, antioxidant enzyme activities (catalase: CAT and superoxide dismutase: SOD), respiratory burst activity, phenoloxidase activity, lysozyme activity and expression of heat shock protein 70 (HSP70) mRNA were measured 0, 3, 6, 12, 24 or 48hours after low salinity treatment with 25, 30, 33 and 35 psu. Survival rates of pacific abalone were 100% at 33 and 35 psu, but 93 and 97% at 25 and 30 psu for 48 hours, respectively. Hemolymph counts decreased in the time elapsed-dependent way at all of the experimental groups. At low salinity, 25 and 30 psu, SOD and CAT activity increased compared to the experimental group of 33 psu. Moreover, respiratory burst activities of the pacific abalone seemed to have no effect on low salinity stress at any experimental group. However, phenoloxidase activity is an important component of the defence against pathogen that was decreased in a reduction of salinity dependent way. Lysozyme activity also immediately reduced at 25 psu experimental group for 48 h. The HSP70 mRNA was weakly expressed at 33 psu, but strongly detectable at 25 psu experimental group. The HSP 70 mRNA expression in gill increased in the time elapsed-dependent way at 25 psu experimental group and then recovered at 48 h. These results suggest that low salinity stress give rise to inhibitory action of immune system as a result of the decrease of phenoloxidase and lysozyme activity in the pacific abalone, especially.

Effects of Fumigation Treatment on the Physiological Changes of Onion Bulbs (훈증처리가 양파의 생리학적 변화에 미치는 영향)

  • Kim, Hyun-Ku;Lee, Hyeong-Choon;Park, Mu-Hyun;Shin, Dong-Hwa
    • Korean Journal of Food Science and Technology
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    • v.18 no.1
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    • pp.6-10
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    • 1986
  • Fumigation of onion bulbs with Tetrachloroisophthalonitrile reduced weight loss by half of the control. The weight losses of the control onion bulbs stored at 80% RH were lower than those stored at 90% RH but no significantly different in case of fumigated onion bulbs. No rooting and sprouting to outside were detected during low temperature storage ($0^{\circ}C$) and $Q_{10}$ value of onion bulbs during storage was the range of 1.9-2.1. The weight losses of onion bulbs during storage were mainly due to decay rather than respiration, because there was positive correlation between weight loss and decay rate during storage period but not respiration ratio.

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Prosthetic rehabilitation in patient with soft palatal defect (연구개 결함을 가진 환자의 보철적 수복)

  • Chang, Myung-Woo;Kim, Jong-Jin;Piro, John D.;Wright, Robert F.
    • The Journal of Korean Academy of Prosthodontics
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    • v.37 no.1
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    • pp.134-138
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    • 1999
  • 연구개는 그 주위조직과 더불어 생리적 기능에 있어 음성, 연하, 및 호흡 등에 중요한 역할을 한다. 종양등의 이유로 인한 연구개의 외과적 절제는 그 해부학적 크기와 모양의 영구적인 변화로 인해 여러기능의 상실을 초래한다. 이에 따른 결함은 과도한 비음, 연하중 음식물이나 유동물의 비관으로의 누출 등을 들 수 있다. 연구개와 그 주위조직의 생리적인 기능의 숙지 및 이를 응용한 보철물(Palatopharyngeal Obturator)의 적절한 제작은 이러한 기능적 결함을 수복하는데 이용되어진다. 본 증례에서는 종양으로 인해 연구개를 절제한 환자의 보철적 수복에 있어, 구강내 온도에 따라 그 형상이 변화하는 인상재를 이용하여, 측-후 인두벽의 운동을 기능적으로 인기하는 방법을 이용하였다. 이러한 방법으로 제작된 보철물은 종양으로 인한 연구개의 절제 후 생리적인 기능의 장애를, 올바른 Palatopharyngeal 폐쇠를 유도함으로써 음질의 향상, 연하등의 기능을 회복시키는데 큰 도움이 될 수 있음을 보여준다.

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A Study of Physiological Changes by The Types of Paralysis Model in Activity Daily of Living (마비모델 유형별 일상생활활동 수행 시 생리적 변화 연구)

  • Sim, Kyoung-Bo;Kim, Dong-Hyun;Kim, Hee-Jung;Moon, Jung-In;Kim, Hyoung-Min
    • The Journal of Korean society of community based occupational therapy
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    • v.1 no.2
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    • pp.21-30
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    • 2011
  • The previous studies were prevalent a study of treatment like a environmental modification or compensative approach and intervention which used in today to paralyzed patients. These interventions were related with occupational therapy widely. The purpose of this study is to provide a basic datum for environmental modification, compensative approach, and intervention observing physiological changes which is shown in early paralyze patients. The subjects were 40 students who were 20 female and 20 male in a college. The students were devided into hemiplegic and paraplegic model. The model was designed using a experimental cloths. A instrument to measure body composition was a precision instrument. The results of the study were as follow: First, there was no different homogeneity between activity daily of living of hemiplegic and paraplegic model. Second, there was a significant different body water and basal metabolic rate between before and after activity daily of living of hemiplegic model. Third, there was a significant different body water and basal metabolic rate between before and after activity daily of living of paraplegic model. Forth, there were no significant different physiological change between after activity daily of living of hemiplegic model and paraplegic model. We observed early changes of body composition using a hemiplegic and paraplegic model. We could know it was reduced body water rate and basal metabolic rate in regardless of type of paralysis. Therefore, it is important to know these physiological changes of paralyzed patients and improve body water and basal metabolic rate of the patients.

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