• 한국지구물리탐사학회:학술대회논문집
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• 2010.10a
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• pp.155-156
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• 2010

포텐셜 자료의 해석을 위해서는 상하향 연속을 이용하는 경우가 많다. 빠른 계산과 다양한 적용성 때문에 FFT(Fast Fourier Transform)을 이용한 상하향 연속을 주로 사용하는데, FFT를 적용하기 위해서는 격자망 형태로 얻어진 자료가 필요하다. 현장 중자력 자료는 보통 산발적(scattered)으로 얻어지기 때문에 FFT를 수행하기 위하여 격자망 자료로 변환하는 격자화(gridding) 과정에서 계산적인 오차가 발생한다. 반면 등가샘(equivalent source) 방법은 주어진 자료에 맞는 가상의 샘(source)들의 조합을 생성하고, 구해진 샘들의 조합으로부터 임의의 영역에서 필드값을 구하므로 격자화 과정이 필요없다. 이 연구의 목적은 등가샘 방법의 필요성을 보이고 여러 가지 등가샘 알고리즘을 비교분석하고 현장 자료에 사용하기 적합한 등가샘 방법들을 보여주는데 있다. 그림 1에서 보듯이 FFT를 사용한 상향 연속은 FFT 이론상 전 영역에 대한 적분이 필요하나 현장에서는 일부분의 자료만을 획득할 수 있으므로 상향 연속에서 정확한 자력값으로 연속을 수행하는 것은 불가능하다. 그러나 주어진 값들로 등가샘을 구성하여 상향 연속을수행한 결과는 상대적으로 보다 정확한 해에 도달한다. 또한 등가샘 방법을 이용한 연속의 장점은 그림 2와 같이 얻어진 자료의 높이가 서로 다른 자료를 주어진 높이로 연속을수행할 수 있다는 점이다. 또한 한번 등가샘들을 구성하면 이를 이용하여 격자화, 필터링 등을 해석을 위한 기초 자료처리에 적용할 수 있다.

• Applied Microscopy
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• v.39 no.1
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• pp.17-25
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• 2009

This study investigated that exposure of male mice to estrogen receptor $\alpha$-selective agonist, 4,4',4"-(4-propyl-[1H]-pyrazole-1,3,5-triyl)tris-phenol (PPT) induce morphological changes of accessory genital glands. The male reproductive organs were fixed and processed for light microscopy. The PPT induced decreases of ventral prostates, seminal vesicles and preputial glands weights with experimental time. The glandular lumen of ventral prostate was atrophied compared with control group. Type of epithelial tissues in the prostate was changed from simple columnar epithelium to stratified cuboidal or squamous epithelium. Treated group with the agonist showed that increased connective tissue underlying epithelium in the prostate and seminal vesicle. Especially, the glandular lumen of the seminal vesicle was contracted when PPT-treated animals were compared with control group. Secretion cells of preputial gland were smaller than that of control group. On week 8, PPT treatment caused decrease of epithelial cell height lining the lumen of preputial gland. These results provide information useful in researching the physiological function of estrogen mediated by estrogen receptor $\alpha$ in male accessory genital gland.

• Journal of Life Science
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• v.18 no.11
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• pp.1543-1550
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• 2008

We studied the effects of smoking, which is one of indoor-environmental pollutants and related to various cancers, on glycoconjugates of rat sebaceous glands with the lectin histochemistry. To investigate the effects of smoking on glycoconjugates, male Sprague-Dawley rats were exposed to tabacco smoke for 10 minutes per day in an inhalation chamber for 1, 2, 3, and 5 days with active and passive exposure. For the structure of sebaceous glands we used PAS reaction, and for the glycoconjugates binding pattern 9 biotinylated lectins (DBA, SBA, PNA, BSL-1, WGA, RCA-1, UEA-1, Con A, and LCA) were used. Some remarkable changes, such as the decrease in the size of sebaceous glandular acini, the destruction of upper portion of sebaceous glands, vacuolation of central portion of sebocytes, and the immature sebaceous glandular acini were seen in the smoke-exposed rats. In the control rats, basal cells were stained with BSL-1, PNA and WGA, but the stronger reaction was founded in BSL-1 binding. Also, sebocytes were stained with PNA, WGA, Con A, BSL-1 and SBA, but stronger reactions were founded in PNA and Con A stainings. Specific changes in the lectin binding patterns were also observed in the smoke-exposed rats. In the basal cells of exposed rats, PNA binding increased, BSL-1 decreased but returned to control level, and WGA disappeared. Plus, immature glandular acini, which were not found in the control rats, were stained PNA, Con A and BSL-1, but the stronger reaction were founded in PNA and Con A binding. In conclusion, it was assumed that the tabacco smoke seriously effected on the structure and glycoconjugates metabolism of sebaceous glands.

• Journal of Life Science
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• v.23 no.12
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• pp.1541-1552
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• 2013

The purpose of this study was to investigate the structure and secretory function of the von Ebner's gland in parasympathetic or sympathetic nerve innervation. Sprague Dawley rats were sacrificed 3, 7, 10, 14, and 21 days after bilateral glossopharyngeal or hypoglossal nerve axotomy, respectively. The circumvallate papilla portion of the tongue was dissected and we observed morphological changes in the von Ebner's gland. The properties of glycoconjugate in the von Ebner's gland were investigated using nine biotinylated lectins (PSA, UEA I, GSL I $B_4$, ECL, DBA, SBA, HPA, SJA, or sWGA). Compared with the control group, cytoplasmic vacuoles appeared in the serous acini of the von Ebner's gland in the 3-day group, and the serous acini were significantly vacuolized and degenerated in the 10-day group after glossopharyngeal nerve axotomy. However, the structure of the von Ebner's gland did not change after hypoglossal nerve axotomy. In the control group, the von Ebner's glands secreted glycoconjugates containing ${\alpha}$-D-galactose, N-acetyl-D-galactosamine, and N-acetyl-D-glucosamine oligomer, and the amount of the secretion decreased significantly in the 10-day group after glossopharyngeal nerve axotomy. However, the amount of the glycoconjugate secretion did not change after hypoglossal nerve axotomy. Therefore, the results of this study suggest that the glossopharyngeal nerve containing parasympathetic nerve fibers is important for maintaining the structure of and secretory function in the von Ebner's gland in rats.

• Journal of Life Science
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• v.19 no.8
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• pp.1067-1072
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• 2009

Stromal derived factor-1 (SDF-1 or CXCL12), one of the CXC chemokines, is widely expressed in many tissues, including the thymus. The thymus can regenerate to its normal mass within 14 days after acute involution induced by cyclophosphamide (CY) in adult rats. Despite the established role of SDF-1 signaling in the development of T and B lymphocytes in the thymus, it has not yet been associated with the regeneration of the adult thymus. The purpose of this study was to investigate whether SDF-1, which is expressed in thymic stromal cells, is modulated during thymic regeneration in adult rats. Here, we showed that SDF-1 mRNAs were expressed in high levels in the thymocyte and thymic stromal cells at day 7 of the CY model. SDF-1 protein was shown to be present at the cortex-medulla junction, paraseptum and within the thymic medulla. Double-immunofluorescence for SDF-1 and ED-1 showed that strong SDF-1 expression was detected in the macrophages of the medulla region displaying immunoreactivity for ED-1 during thymus regeneration. Taken together, our results demonstrated that SDF-1 expression increased in regenerating thymic macrophages, suggesting the roles of SDF-1 as a chemo-attractant for damaged cells produced in the process of thymic regeneration after acute involution induced by CY.

• Journal of radiological science and technology
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• v.34 no.3
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• pp.189-193
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• 2011

Sitting position upper extremity X-ray examinations (SUEX) is the most widely used patient positioning method for upper extremity X-ray examinations. For this method, the radiation dose is considerable for relatively less interesting organs. We investigated whether patients need to wear the apron during the examination or not. We also studied the examination methods which can reduce the radiation dose. The results showed that radiation dose was reduced as the distance of source to patient becomes longer and the thickness of object grows higher.

• Journal of the korean academy of Pediatric Dentistry
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• v.26 no.2
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• pp.350-364
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• 1999

The distribution of mast cells and nerves were investigated in the submandibular and sublingual glands of postnatal rats, using morphometric, histochemical and immunohistochemical techniques. Mast cells were observed in the submandibular and sublingual glands of postnatal development. Number of mast cells gradually increased in both glands following development. At birth, mast cells were relatively fewer in submandibular gland than those in sublingual gland, and they were mainly distributed in parenchymal tissues. At $2{\sim}4$ weeks, most of the mast cells were observed in the connective tissues, surrounding neurovascular elements, but some mast cells were closely related with the acini of submandibular gland. PGP 9.5 immunoreactive nerve fibers were found in the submandibular and sublingual glands of all developmental age. The nerve fibers were showed in varicose shape, and mainly located in adjacent area of ducts and vascular components of both glands. The number of nerve fibers were increased rapidly until 8 weeks, but they were not increased any more until 24 weeks. Therefore, it is suggested that mast cells and nerve fibers related with each other, and that their interactions may play roles not only in maturation of secretory units but also growth and differentiation of the tubular structures of the rat submandibular and sublingual glands during postnatal development.

• Journal of Life Science
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• v.17 no.7 s.87
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• pp.923-930
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• 2007

Thymus can regenerate to its normal mass within 14 days after acute involution induced by cyclophosphamide (CY) in adult rat. Despite the established role of Wnt pathways in the process of thymus development, they have not yet been associated with the regeneration of adult thymus. The purpose of this study was to investigate whether Wnt7b, which is expressed in developing thymic epithelial cells rather than in thymocytes, is modulated during thymic regeneration in adult rat. Here, we show that Wnt7b expression was up-regulated in the regenerating thymus. Cells immunolabeled for the Wnt7b were identified as macrophages. Furthermore, Wnt7b gene expression was decreased by the treatment of receptor activator of NF-kappaB ligand (RANKL). Taken together, our results demonstrate that Wnt7b gene expression was increased in macrophages during thymic regeneration and negatively regulated by RANKL.

• Journal of the Korean Society of Radiology
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• v.85 no.2
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• pp.445-450
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• 2024

Gastric metastasis (GM) from cervical cancer is extremely rare, and only a few cases have been reported in the English literature. Gastric-type mucinous adenocarcinomas (GAS) of the uterine cervix are rare. GAS is an aggressive cancer commonly found in advanced stages; however, GM has not been reported. This study presents a rare case of GM from GAS of the uterine cervix in a 61-year-old female and describes the radiological findings of both the GM and cervical mucinous adenocarcinoma. GM appeared as a poor enhancing submucosal mass. The cervical mucinous adenocarcinoma appeared as an infiltrating mass with poor contrast enhancement. It exhibited mildly high and low signal intensities on the diffusion-weighted image and apparent diffusion coefficient map, respectively. This case is extremely rare and challenging to diagnose; however, if cervical cancer is an human papillomavirus-independent GAS type and a submucosal lesion is found in the stomach, the possibility of metastasis with a pattern similar to our case could be considered.

• The Safety technology
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• no.149
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• pp.15-17
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• 2010

샘표식품주식회사는 1946년 창립 이래 전통 식품인 간장, 된장, 고추장 분야에 올곧게 매진해 온 한국의 대표 발표식품 기업이다. 현존하는 한국 최장수 상표인 '샘표'브랜드로(1954년 등록번호 362호) 한국 간장 소비시장에서 약 50% 이상의 점유율을 차지할 만큰 큰 사랑을 받고 있는 샘표는 국민 건강과 식문화 발전에 이바지하고, 국내 소비자뿐만 아니라 전세계인에게 한국 전통 장류의 맛을 전하기 위해 노력하고 있다.