• Journal of the Korean Institute of Intelligent Systems
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• v.27 no.1
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• pp.15-21
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• 2017

In this paper, the decentralized fuzzy observer design technique is presented for discrete-time nonlinear interconnected systems, which are assumed to be with unknown interconnections. To design the decentralized fuzzy observer, the design problem is considered and the performance function is defined to solve the design problem. Based on the performance function, the sufficient condition is derived for the observer design, and its condition is formulated into linear matrix inequalities. Finally, by the simulation result, the validity of the proposed observer design technique is shown.

• Proceedings of the Korean Institute of Intelligent Systems Conference
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• 2008.04a
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• pp.377-380
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• 2008

본 논문은 시간 지연을 가지는 비선형 상호 결합 시스템에 대한 분산 퍼지 출력 궤환 제어기를 제시한다. Takagi-Sugeno (T-S) 퍼지 모델링을 통하여 비선형 상호 결합 시스템을 퍼지 모델로 표현한다. 상호 결합 시스템의 하위 퍼지 시스템을 안정화 시킬수 있는 분산 출력 궤한 제어기를 설계한다. 폐루프 하위 시스템들의 안정도 조건을 선형 행렬 부등식으로 나태내고, 부등식을 이용하여 제어기의 이득값을 구한다. 모의실험을 통하여 시간 지연이 있는 비선형 상호 결합 시스템에 대한 분산 퍼지 출력 궤한 제어기의 효용성을 평가한다.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.47 no.10
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• pp.67-73
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• 2010

In this paper, the effect of a finite substrate on the mutual coupling of a pair of microstrip patch antennas along the H -plane is investigated. The mutual coupling of a pair of microstrip patch antennas can be reduced using the interference effect due to the phase difference by a variety of routes of the surface wave. In the case of the substrate with $\varepsilon_r$=10 and thickness of 3.2 mm, the mutual coupling is reduced by 4.85 dB on the substrate size with the strong mutual coupling, while the mutual coupling is reduced by 34.28 dB on the substrate size with the weak mutual coupling when the distance between the antenna centers is varied from 0.5 $\lambda_0$ to 1.0 $\lambda_0$. In the case of optimization substrate size, the decreasing rate of the mutual coupling with the increase of the distance between the antenna centers is very large. Good agreements between the image method and full wave simulation results are obtained.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.48 no.4
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• pp.92-99
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• 2011

Effect of a finite grounded substrate on mutual coupling characteristics of a 2-element array antenna using inductor loaded patch antennas is investigated. The mutual coupling characteristics of a 2-element array antenna using inductor loaded patch antennas positioned along the E-plane are compared with those positioned along the H-plane. The magnitude of mutual coupling is very small and the distance between the center of element and the substrate edge on the E-plane for the minimum mutual coupling is similar regardless of the direction at which antenna elements are positioned in the case of a 2-element array antenna using inductor loaded patch antennas.

• Journal of the Korean Institute of Telematics and Electronics
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• v.22 no.6
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• pp.46-52
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• 1985

A theoretical study of mutual coupling effects between two H-plane coupled microstrip patch antennas is presented. The radiation resistance and slot capacitance of a single micro-strip patch are calculated. To investigate the mutual coupling effects, the even and odd mode characteristic impedance and effective dielectric constants are obtained using the coupled microstrip line model. The S-parameter matrix elements 511,512 are used to study the mutual coupling e(facts in S-band frequency ranges for various patch spacings. Theoretical results and measurements are in good agreement.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.9 no.2
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• pp.415-421
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• 2005

The radiating or receiving characteristics of array elements (i.e., antennas) are changed from those of isolated elements due to mutual coupling effects and the array performance becomes different from those originally designed by assuming isolated elements. The effects of mutual coupling on the performance of a rectangular array with triangular grid geometry of dipoles above a ground plane are discussed with respect to element pattern. The concept of element gain function is used to examine the effects of mutual coupling on the array performance in terms of sidelobe level in the uniformly spaced and space-tapered rectangular arrays with triangular grid geometry of dipoles. It was shown that the sidelobe performance improved in the space-tapered array compared to the uniformly spaced array in the presence of mutual coupling effects. Computer simulation results are presented.

• Journal of the Korean Institute of Intelligent Systems
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• v.25 no.5
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• pp.451-456
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• 2015

In this paper, an observer-based decentralized fuzzy controller is designed for discrete-time interconnected fuzzy systems. Based on the fuzzy subsystem of the interconnected fuzzy system, the observer-based decentralized fuzzy controller is considered. By using the fuzzy subsystem and the observer-based decentralized fuzzy controller, the closed-loop system is obtained. From the closed-loop system, the stability condition with the maximum interconnection bound is developed, and its sufficient condition is represented as the linear matrix inequality (LMI). Finally, the numerical example is provided to verify the effectiveness of the proposed technique.

• Proceeding of EDISON Challenge
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• 2017.03a
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• pp.158-164
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• 2017

암을 억제시키는 기능을 하는 단백질로 잘 알려진 p53은, 주로 종양세포에서 과도하게 발현되는 단백질인 HDM2와 복합체를 형성하여 비활성화되고 항암기능을 상실하게 됩니다. 때문에 종양세포에서의 p53-HDM2의 상호작용을 억제하기 위해 현재까지 많은 연구가 진행되어왔으며, 다양한 p53-HDM2 억제제가 개발된 바 있습니다. 최근 연구들에 따르면, HDM2와 결합친화도를 높이고 소수성 작용(hydrophobic interaction)에 기여하여 보다 안정한 구조를 만드는 탄화수소체인(staple)을 연결시킨 펩타이드 설계에 대한 관심이 높아지고 있는 추세입니다. 이에, 본 연구에서는 분자동역학 모의실험을 통해서 얻은 탄화수소체인-p53과 비탄화수소체인-p53 및 각각의 HDM2와 결합한 복합체를 기반으로 EDISON의 용매화 자유에너지(Solvation Free Energy) 프로그램을 이용하여 탄화수소체인의 특징 및 역할을 구조적인 측면과 열역학적인 측면으로 분석하여 비교하고자 합니다. 우리 연구에서 비탄화수소체인-p53의 구조는 분자동역학 시뮬레이션을 수행하는 동안 나선구조형태로 풀려 HDM2와 결합 유도 시에 주요결합 아미노산 잔기가 올바른 결합부위와 상호작용하지 못한 결과를 확인한 반면, 탄화수소체인이 형성된 구조는 시뮬레이션 동안에도 펩타이드의 나선구조를 유지시켜 HDM2와 주요 결합을 형성하는 아미노산 잔기들을 올바른 방향으로 배치시켜 HDM2와의 결합친화도를 높였습니다. 이 연구 결과는 탄화수소체인이 펩타이드의 나선성을 유지시키고, HDM2와의 상호작용을 통한 구조적인 안정성 유도 및 용매화 자유에너지에 큰 기여를 통해 p53-HDM2상호작용 억제제에서 긍정적인 역할을 할 가능성을 보여줍니다.

• Economic and Environmental Geology
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• v.35 no.6
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• pp.567-573
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• 2002

Two-dimensional MT (Magneto-Telluric) modeling is performed to verify the validity of difference arrow for GDS(Geomagnetic Depth Sounding) survey. The electromagnetic mutual coupling between the sea and in-land conductor is used as a criterion that judges the validity of difference arrow. In this study, the mutual coupling between them is examined according to the spatial distance between them and the period of magnetic variations. The difference arrow is valid for conductors located at surface which are far from the sea or when the long period is used, but the mutual coupling is weak for buried conductor in all the periods. However, when a conductor extends vertically down to the deep part, the validity of difference arrow is in doubt, since the strong mutual coupling influences up to the long period. Therefore, to remove the known conductor effect such as sea effect from the observed induction arrow, the mutual coupling between them must be examined and the caution must be exercised in interpreting the resultant difference arrow if mutual coupling between them is strong.

• Journal of Life Science
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• v.23 no.11
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• pp.1311-1316
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• 2013

Heterogeneous nuclear ribonucleoprotein L (hnRNP L) is a major pre-mRNA binding protein and it is an abundant nuclear protein that shuttles between the nucleus and the cytoplasm. hnRNP L is known to be related to many cellular processes, including chromatin modification, pre-mRNA splicing, mRNA export of intronless genes, internal ribosomal entry site (IRES)-mediated translation, mRNA stability, and spermatogenesis. In order to identify the cellular proteins interacting with hnRNP L, this study performed a yeast two-hybrid screening, using a human liver cDNA library. The study identified insulin-like growth factor binding protein-4 (IGFBP-4) as a novel interaction partner of hnRNP L in the human liver. It then discovered, for the first time, that hnRNP L interacts specifically with IGFBP-4 in a yeast two-hybrid system. The authenticity of this two-hybrid interaction of hnRNP L and IGFBP-4 was confirmed by an in vitro pull-down assay.