• Fiber Technology and Industry
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• v.8 no.2
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• pp.172-182
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• 2004

이상적인 상처 치료제는 상처 치유가 신속하고 효과적으로 이루어질 수 있는 환경을 제공하며 상처가 회복된 후 흉터를 최소화한다. 이러한 상처치료 목적을 위해 상처 드레싱은 지혈, 삼출물 흡수, 통증 완화, 약물투여, 외부 자극으로부터의 보호, 감염 방지 및 은폐 등의 기능을 갖추어야 한다. 고대로부터 상처 처방으로 거미줄, 동물의 배설물이나 기름, 나뭇잎, 꿀 등 다양한 천연물들을 이용해 왔다［1-4］. 그러나 이러한 재료를 이용한 드레싱은 미생물에 의한 감염이 쉽게 일어나 부작용이 많았다. (중략)

• 방재와보험
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• s.108
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• pp.64-67
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• 2005

여름철에는 덥고 습한 날씨가 이어져 사람들은 최대한 신체를 노출시켜 시원함을 유지하고자 한다. 따라서 뜨거운 수증기나 국물에 데거나 다리미 등의 뜨거운 쇠붙이에 의해 접촉화상을 입는 경우가 흔하다. 이런 경우 심한 통증과 상처가 생기게 되는데, 대부분의 사람들은 당황하여 어떻게 대처해야 할지 몰라 우왕좌왕하기 마련이다. 일부의 사람들은 간장이나 된장, 알로에 등을 상처에 바르는 등 전근대적인 방법으로 상처를 치료하다가 상처를 키워서 병원에 가기도 하고, 심지어는 창상을 그대로 노출시켜 세균에 의한 감염이 발생되어 얕은 화상이 더욱 깊어져 치료만으로 나을 수 있는 상처를 피부이식술 등의 수술을 필요로 하게 되는 결과를 낳기도 한다. 또한 수술을 하는 정도는 아니더라도 화상흉터가 많이 남게 될 수도 있어 초기의 화상관리가 중요하다 하겠다. 과연 독자들은 화상상처에 어떻게 대처하는지? 초기에 상처를 어떻게 돌보는가에 따라 평생 화상흉터의 멍에를 지고 갈수 있다는 것을 알고 있는지? 이러한 많은 문제점들에 대한 관리적인 차원에서 일반인들이 어렵고 복잡하다고 생각할 수 있는 화상관리에 대해 이야기해 보고자 한다. 화상이 생겼을 때의 처치는 일반적인 열창 때의 처치와는 다른 점이 있다. 우선 열에 의해 피부가 손상을 받아 이를 식히는 과정이 필요하며 이 과정(찬물로의 창상세척)이 간과될 경우 이차적 점은 화상에 의한 상처는 손상된 피부로 인해 노출된 생살을 어떻게 세균감염으로부터 보호하느냐 하는 점이 문제가 되며 이를 예방하는 과정이 필요하다는 것이다.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.10 no.11
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• pp.3434-3443
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• 2009

This study was done to examine patients' wound care knowledge and concerns prior to discharge from a tertiary hospital. The participants in this descriptive survey were 112 patients having wounds. During interview, a structured self-administered questionnaire was filled out. The participants were 71 males and 41 females. Wound types were surgical incision (52.7%), percutaneous wound (26.8%), pressure ulcer (9.8%) and diabetic foot and arterial ulcers (5.4%). Their wound care knowledge was 52.0% of correct answer and the mean of concerns (range 1-7) was 2.79. There was no significant correlation between their knowledge and concerns of wound care. The factors influence on wound care concerns were fear of wound care, wound pain, length of hospital stays, and perceived health condition. This findings showed that discharge patients with a wound had some incorrect knowledge and various concerns about wound care. They may help to direct patient teaching in discharge plan.

• Proceedings of the KOSOMBE Conference
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• v.1995 no.11
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• pp.235-238
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• 1995

모든 살아있는 조직은 표면전위(surface electropotentials)를 가지고 있으며, 이는 조직에 손상를 가져오는 상처가 발생되었을 때 그 상처를 치료하는데 큰 역할을 담당하고 있다. 즉, 상처부위에 인위적으로 표면전위의 특성을 가진 전기적인 자극을 가함으로서 상처의 치료효과를 높일 수 있으며, 그 중에서도 상처의 발생 직후에 음(-)의 전기자극을 가할 때 높은 치료효과를 나타내는 것으로 알려져 있다. 본 연구는 상처의 치료에 전기자극을 사용할 때, 자극의 특성 변화가 치료의 효과를 높일 수 있는가에 대한 기초 연구로서 수행하였다. 즉, 쥐의 복부부위를 일정한 크기로 절개하고, 그 부위에 1mA와 10mA의 자극 펄스를 지속시간을 10msec와 100msec로 변화하면서 $1\sim3$일간 제시한 후 상처가 치료된 정도를 비교하였다. 모든 자극이 끝난 후 상처부위에 대한 조직검사를 수행하여 육아조직(granulation tissue)의 상태를 관찰하였다. 그 결과 전기자극을 전혀 가하지 않은 그룹에 비하여 전기자극을 행한 그룹들의 육아조직에 있어서 그 형성 상태가 양호하였고, 괴사현상이 나타나지 않았으며, 염증의 정도가 낮게 나타났음을 발견하였다. 또한, 자극의 횟수를 증가할수록 전기자극으로 인한 치료의 효과가 크게 나타났음을 알 수 있었다. 그러나, 각 그룹 내에서 자극의 특성을 변화시키며 수행한 검사의 결과는 큰 차이를 보이지 않았다.

• The Korean Journal of Pesticide Science
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• v.20 no.2
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• pp.83-92
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• 2016

New tree wound-treatment formulations (WTF) were developed in this study. Stimulating effects of plant growth regulating substance on callus formation were evaluated in vivo twig disc culture of Zelkova serrata, Ziziphus jujuba, Pinus densiflora, Ginkgo biloba. and Aesculus turbinata. Based on the evaluation, WTF were prepared with 2,4-D, NAA, and IBA using xanthan gum as an extending agent. WTF were pasted on $2{\times}10cm$ artificial wound on the stem and the effects were evaluated 12 weeks later with the thickness of new callus-tissues. The effects varied with tree species and the growth regulators. In Z. serrata and A. turbinata, 2 mg/L of 2,4-D was the best WTF. In P. koraiensis and G. biloba, 8 mg/L of NAA and 1 mg/L of IBA were the best, respectively. Callus formation was quite lower in G. biloba compared to other species. Stimulating effect of thiophanate-methyl paste was excellent only in Z. serrata and lower than certain WTF in other species. Vaseline, which was used generally as an WTF, remained longer on the wound and causing decay. From the results, it could be recommended that 2,4-D, NAA and IBA were the best WTF for Z. serrata/A. turbinata, P. koraiensis and G. biloba, respectively.

• Journal of Life Science
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• v.29 no.3
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• pp.382-393
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• 2019

Wound care is a health industry concern affecting millions worldwide. Recent increase in metabolic disorders such as diabetes comes with elevated risk of wound-based complications. Treatment and management of wounds are difficult practices due to complexity of the wound healing process. Conventional wound dressings and treatment applications only provide limited benefits which are mainly aimed to keep wound protected from external factors. To improve wound care, recent developments make biopolymers to be of high interest and importance to researchers and medical practitioners. Biopolymers are polymers or natural origin produced by living organisms. They are credited to be highly biocompatible and biodegradable. Currently, studies reported biopolymers to exhibit various health beneficial properties such as antimicrobial, anti-inflammatory, hemostatic, cell proliferative and angiogenic activities which are crucial for effective wound management. Several biopolymers, namely chitosan, cellulose, collagen, hyaluronic acid and alginic acid have been already investigated and applied as wound dressing agents. Different derivatives of biopolymers have also been developed by cross-linking with other molecules, grafting with other polymers, and loading with bioactive agents or drugs which showed promising results towards wound healing without any undesired outcome such as scarring and physiological abnormalities. In this review, current applications of common biopolymers in wound treatment industry are highlighted to be a guide for further applications and studies.

• Journal of the Korean Society of Physical Medicine
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• v.8 no.3
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• pp.449-456
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• 2013

목적: 본 연구는 저강도 맥동 초음파적용이 흰쥐의 전층 상처 치유와 아교질 축적 및 아교질 mRNA발현에 미치는 영향을 규명할 목적으로 시행하였다. 방법: 12마리의 Sprague-Dawley계 흰쥐를 저강도 맥동 초음파군(n=6)과 대조군(n=6)에 무작위 배정하고 등에 $19.63mm^2$ 크기의 전층 적출 상처를 만든 다음 저강도 맥동 초음파군은 3 MHz, 순환주기 20%, SATA 강도 $0.4W/cm^2$로 1일 1회, 1회 5분씩 초음파를 적용하고, 대조군은 가짜 초음파를 적용하였다. 7일간 처치 후 초음파군과 대조군의 아교질 축적, 아교질 mRNA 발현, 상처치유율, 절반치유시간을 비교하였다. 결과: 초음파군의 아교질 축적(p<05)과 아교질 mRNA 발현(p<.01)이 대조군보다 유의하게 증가하였고, 상처치유율(p<.05)과 절반치유시간(p<.0)도 초음파군의 대조군보다 유의하게 빨랐다. 결론: 본 연구에서 전층 상처에 저강도 맥동 초음파를 적용한 결과 상처 치유가 촉진되었고 육아조직에 아교질 축적이 증가하였다. 이러한 결과는 맥동 초음파의 기계적 자극이 제 1형 아교질 mRNA 전사활동을 촉진시키는 것으로 사료된다.

• Journal of Digital Contents Society
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• v.14 no.4
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• pp.597-604
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• 2013

The purpose of this study is to design and implement an application for the smartphone in order to cure the wounded heart of the youth. The heart of the youth can be wounded regardless of their willingness in growing. Not only the wounded heart is hardly cured, but also it can diverse the direction of one's life. It has been tried to adopt color reflection to the smartphone which is accustomed to them. A color reflection curing application based on the smartphone is designed and implemented. The application has been tested with 15 teachers, they were satisfied with it.

• Journal of Digital Convergence
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• v.10 no.9
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• pp.311-317
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• 2012

This study suggested ontology design to help heart-wounded users to be healed from their wounded heart. The ontology development framework which this article applied or adapted was mainly based on 9-step ontology development frameworks suggested by E. King and Reinold. The procedures of this study were collections and classification of related technical terms following the definitions of ontology and ontology users. In case added technical terms in the process of the study was founded, the definitions of their synonyms was utilized to complete ontology design. In addition, this article presented possibilities of offering new information by combining various characteristics of wounded heart, activating the expansion of ontology conception.

• Applied Microscopy
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• v.27 no.1
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• pp.71-86
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• 1997

The regeneration and differentiation of the cutaneous pigment system in the goldfish, Carassius auratus during the wound healing process were studied with high magnification electron microscope. The cutaneous pigment cells of the normal tissues were composed of three kinds of dermal chromatophores-xanthophores, leucoiphores and melanophores. While xanthophores contain two kinds of pigment granules-pterinosomes and carotenoid vesicles, leucophores and melanophores contain amorphous pigment granules (leucosomes) and oval shaped electron dense melanin pigment granules (melanosomes) respectively. After injury, primary wound healing responses being carried out by migration of epidermal cells and hemocytes spreading over the wound surface at the day of wounding. And at the time of primary wound closure, 5 to 7 days after wounding, rER rich cells-presumably common precursors of dermal chromatophores-immigrated into the wound area. First redifferentiated chromatophores appeared 3 weeks after wounding. Pigment granules of the chromatophores were emerged from the cytoplasmic Golgi complex via rough endoplasmic reticulum. Pinocytotic vesicles which associated with accumulation of pigment material, appeared only at the inner surface of the chromatophores adhering to the rER rich cells, characteristically. The differentiation of each chromatophore in addition to integumental wound repair were accomplished within 4 weeks after wounding at most cases, however the total numbers and densities of these repaired chromatophores still primitive state. Moreover, It has been revealed that complete repair of chromatophores at wounded tissues from burns requirs more than 3 months in normal environment.