• Journal of Digital Contents Society
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• v.14 no.4
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• pp.597-604
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• 2013

The purpose of this study is to design and implement an application for the smartphone in order to cure the wounded heart of the youth. The heart of the youth can be wounded regardless of their willingness in growing. Not only the wounded heart is hardly cured, but also it can diverse the direction of one's life. It has been tried to adopt color reflection to the smartphone which is accustomed to them. A color reflection curing application based on the smartphone is designed and implemented. The application has been tested with 15 teachers, they were satisfied with it.

• Journal of the Korean Society of Physical Medicine
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• v.8 no.3
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• pp.449-456
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• 2013

목적: 본 연구는 저강도 맥동 초음파적용이 흰쥐의 전층 상처 치유와 아교질 축적 및 아교질 mRNA발현에 미치는 영향을 규명할 목적으로 시행하였다. 방법: 12마리의 Sprague-Dawley계 흰쥐를 저강도 맥동 초음파군(n=6)과 대조군(n=6)에 무작위 배정하고 등에 $19.63mm^2$ 크기의 전층 적출 상처를 만든 다음 저강도 맥동 초음파군은 3 MHz, 순환주기 20%, SATA 강도 $0.4W/cm^2$로 1일 1회, 1회 5분씩 초음파를 적용하고, 대조군은 가짜 초음파를 적용하였다. 7일간 처치 후 초음파군과 대조군의 아교질 축적, 아교질 mRNA 발현, 상처치유율, 절반치유시간을 비교하였다. 결과: 초음파군의 아교질 축적(p<05)과 아교질 mRNA 발현(p<.01)이 대조군보다 유의하게 증가하였고, 상처치유율(p<.05)과 절반치유시간(p<.0)도 초음파군의 대조군보다 유의하게 빨랐다. 결론: 본 연구에서 전층 상처에 저강도 맥동 초음파를 적용한 결과 상처 치유가 촉진되었고 육아조직에 아교질 축적이 증가하였다. 이러한 결과는 맥동 초음파의 기계적 자극이 제 1형 아교질 mRNA 전사활동을 촉진시키는 것으로 사료된다.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.20 no.1
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• pp.14-24
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• 1994

Mma-5 and Malva are extracts from a defined seaweed of the Rhodophyceae family and an annual or perenial plant, respectively. They have traditionally a significant stimulating properties such as protein synthesis, astringent, emollient, and et al.. In order to investigate the effect on wound healing, we studied for cell migration, cell attachment, and cell proliferation in vitro. The results of present study demonstrated that MMA-5 and Malva extract had the effect on wound healing, therefore we suggested that they could be effective materials to be applied to Cosmetic products.

• Journal of fish pathology
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• v.34 no.2
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• pp.233-241
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• 2021

Polydeoxyribonucleotide (PDRN) is known to accelerate wound healing process by acting on specific adenosine receptors. Differently from the PDRN substances obtained so far from piscine tissues, unique PDRN was prepared recently from Porphyra, a seaweed species. In this study, effects of the Porphyra PDRN was evaluated by inducing artificial skin wounds in Nile tilapia Oreochromis niloticus. The wound recovered almost completely in 2 weeks without any treatment, however only a partial recovery was done after one week. Facilitated healing was observed by PDRN fed for 5 days before wound induction at 10 or 20 mg/kg, against the partially recovered 1-week old wound. The healing effects were identified not only by visual observation, wound area measurement, but also by colorimetric estimations. These novel wound healing effects suggest beneficial therapeutic utility of Porphyra-derived PDRN for wound treatments in fishes occurring from various causes.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.4
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• pp.242-249
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• 2019

This study examined the wounds and healing of the character as a woman in Samuel Beckett's play, Happy Days, through a microscopic approach by focusing on her inner I, and to study how she tries to heal her wounds. Winnie in Happy Days spends hard times not recognizing her internal wounds and pains. By facing her wounds and pains, however, she starts the process of self-healing, mainly through communicating and sharing her sorrows with her past inner child. Winnie's positive and optimistic character appears to change Willie's behaviors, which may be a positive sign that her wounds and pains will possibly be healed. In conclusion, Winnie has a chance to face her inner wounds and pains while interacting and communicating with her husband Willie, and she is slowly heading for healing her wounded inner I.

• Journal of Adhesion and Interface
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• v.22 no.2
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• pp.47-56
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• 2021

Steel plates coated by self-healable polymer still can be rusted since it takes time to be healed. In this study, dual self-healing coating material is developed using corrosion inhibitor (DTBEDA) which can form hindered urea (HUB) as reversible cross-linking bond at the same time. Developed dual self-healing polymer is coated on steel plate, and scratch healing property was investigated by surgical blades and nano/micro indentation tester. The anticorrosion effect of DTBEDA was investigated by electrochemical impedance spectroscopy (EIS).

• Applied Microscopy
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• v.27 no.1
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• pp.71-86
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• 1997

The regeneration and differentiation of the cutaneous pigment system in the goldfish, Carassius auratus during the wound healing process were studied with high magnification electron microscope. The cutaneous pigment cells of the normal tissues were composed of three kinds of dermal chromatophores-xanthophores, leucoiphores and melanophores. While xanthophores contain two kinds of pigment granules-pterinosomes and carotenoid vesicles, leucophores and melanophores contain amorphous pigment granules (leucosomes) and oval shaped electron dense melanin pigment granules (melanosomes) respectively. After injury, primary wound healing responses being carried out by migration of epidermal cells and hemocytes spreading over the wound surface at the day of wounding. And at the time of primary wound closure, 5 to 7 days after wounding, rER rich cells-presumably common precursors of dermal chromatophores-immigrated into the wound area. First redifferentiated chromatophores appeared 3 weeks after wounding. Pigment granules of the chromatophores were emerged from the cytoplasmic Golgi complex via rough endoplasmic reticulum. Pinocytotic vesicles which associated with accumulation of pigment material, appeared only at the inner surface of the chromatophores adhering to the rER rich cells, characteristically. The differentiation of each chromatophore in addition to integumental wound repair were accomplished within 4 weeks after wounding at most cases, however the total numbers and densities of these repaired chromatophores still primitive state. Moreover, It has been revealed that complete repair of chromatophores at wounded tissues from burns requirs more than 3 months in normal environment.

• Journal of Digital Convergence
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• v.12 no.5
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• pp.467-477
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• 2014

The goal of this study is to explore 'color meditation programs' for wounded heart healing of University students. Color meditation was found to alleviate negative psychological symptoms of young people and to raise their quality of life. Furthermore this survey was investigated in a way that participants who are not familiar with meditation activities could access this program without resistance. Also the characteristic points of this program are to be properly reconstructed and supplemented so that it can be applied without any limitations in schools. The satisfaction with color meditation program rather than the motivation of participation in it was determined to affect mental health. These results suggest that simply participating in color meditation program does not mean influencing mental health. Understanding and being satisfied with color meditation was found to be the key to mental health.

• Fiber Technology and Industry
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• v.8 no.2
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• pp.172-182
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• 2004

이상적인 상처 치료제는 상처 치유가 신속하고 효과적으로 이루어질 수 있는 환경을 제공하며 상처가 회복된 후 흉터를 최소화한다. 이러한 상처치료 목적을 위해 상처 드레싱은 지혈, 삼출물 흡수, 통증 완화, 약물투여, 외부 자극으로부터의 보호, 감염 방지 및 은폐 등의 기능을 갖추어야 한다. 고대로부터 상처 처방으로 거미줄, 동물의 배설물이나 기름, 나뭇잎, 꿀 등 다양한 천연물들을 이용해 왔다［1-4］. 그러나 이러한 재료를 이용한 드레싱은 미생물에 의한 감염이 쉽게 일어나 부작용이 많았다. (중략)

• Applied Chemistry for Engineering
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• v.22 no.6
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• pp.599-604
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• 2011

In this study, we investigated the efficacy of ${\beta}$-cyclodextrin (${\beta}CD$) hydrorogel containing silk fibroin (SF) on healing burnt wound. Tosyl ${\beta}CD$ was conjugated to polyethyleneimine (PEI) using epichlorohydrin (EPI) as a cross-linker. The ${\beta}CD/PEI/SF$ hydrogel was applied on the back of mouse and then the efficacy of hydrogel was compared with both positive control group and negative control group. There was no wound healing efficacy showed neither in the drug loaded ${\beta}CD/PEI/SF$ hydrogel group nor in the drug unloaded ${\beta}CD/PEI/SF$ hydrogel group. On the other hand, in the positive control group, a significant reduction of the wound size after the usage of OTC hydrorogel was obtained. The burn-healing histological result showed a similar phenomenon. After hematoxylin-eosin staining the skin induced by burning, and the epithelial growth observed in the dermis, the efficacy of ${\beta}CD/PEI/SF$ hydrogel in healing burnt wound could not be clearly identified.