• Title/Summary/Keyword: 산삼

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기술개발성공사례 - (주)마이크로프랜츠

  • Korean Federation of Science and Technology Societies
    • The Science & Technology
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    • v.32 no.7 s.362
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    • pp.78-79
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    • 1999
  • 유전공학기법으로 산삼이나 가시오갈피 등 약재를 대량 생산할 수 있는 새로운 기술을 개발하고 있는 (주)마이크로프랜츠는 주목받는 벤처기업이다. 전주에 있는 이 기업은 생약제재의 종자에서 분리한 세포를 액체 배지에서 배양한 다음 증식된 세포들을 체세포배 발생 과정을 거친 결과 뿌리와 잎을 갖춘 유식물체(싹이 튼 식물체)를 얻는데 성공했다. 이러한 조직배양 방법은 완전 무공해 약재를 생산할 수 있고 6년 걸리는 자연재배를 3개월이며 생산할 수 있는 장점을 지니고 있다.

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Characterization of Polyacetylene Contents in Wild Mountain Ginseng and Cultured Ginseng (산삼 및 재배인삼의 폴리아세틸렌 함량 특성)

  • 장문식;유병삼;변상요
    • KSBB Journal
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    • v.18 no.6
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    • pp.440-442
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    • 2003
  • Panaxynol and panaxydol are major polyacetylene compounds in Ginseng and Wild Mountain Ginseng. Their contents in Korean wild mountain ginseng, Chinese mountain ginseng, and cultured ginseng were analysed by GC with FID. The content ratio of panaxynol to panaxydol was clearly different in various ginsengs. They were 1.81, 0.87, and 0.42 for Korean wild mountain ginseng, Chinese wild mountain ginseng, and cultured ginseng, respectively. The ratio difference could be used as a marker to identify various ginseng from different sources.

Antidepressant Effect of the Subchronic Administration of the Methanolic Extract of Wild-ginseng and Cultivated-ginseng in Mice Tail Suspension Test (산삼과 인삼 메탄올 추출물 아만성 복용의 Mice Tail Suspension Test에서의 항우울 효과에 대한 비교연구)

  • Kwon, Sun-Oh;Choi, Soo-Min;Kim, Myung-Hwan;Lee, Bom-Bi;Park, Moo-Won;Lee, Hye-Jung;Park, Hi-Joon;Hahm, Dae-Hyun
    • Journal of Acupuncture Research
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    • v.26 no.4
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    • pp.99-106
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    • 2009
  • Objectives : The antidepressant effect of the subchronic administration of the methanolic extract of wild ginseng(WG) was investigated compared with that of cultivated ginseng(CG, panax ginseng) extract. Methods : To assess the antidepressant effect of the ginseng extracts, tail suspension test(TST) was executed in mice after daily administration of WG or CG extract for five consecutive days. Results : The WG extract at daily dose of 600mg/kg significantly reduced the total duration of immobility in the TST, whereas there was no significant reduction at daily dose of 300mg/kg WG and 600mg/kg CG. There were no individual differences between experimental groups in open field test (OFT) to evaluate psychostimulant effects of WG or CG extract. In the high performance liquid chromatography(HPLC) analysis of the extracts, it was found that WG included four times more ginsenoside Rg1 and Re, three times more Rf, and six times more Rb1 and Rc than CG. Conclusions : It is suggested that WG extract has stronger antidepressant effect than CG extract, which means it includes more antidepressant compounds than CG.

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Effects of Dietary Therapy with Korean Herbal Medicine and Cultivated Wild Ginseng Pharmacopuncture on Change of Body Composition: A Retrospective Study (산삼복합약침과 한약을 병행한 식이요법이 체성분 변화에 미치는 영향: 후향적 연구)

  • Lee, Jin-Hyuck;Kim, Seon-Jong;Lim, Jung-A;Shin, Jung-Min
    • Journal of Korean Medicine for Obesity Research
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    • v.22 no.1
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    • pp.86-92
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    • 2022
  • The purpose of this study was to investigate the effects of dietary therapy with Korean herbal medicine and cultivated wild ginseng pharmacopuncture on change of body composition retrospectively. We analyzed the medical records of 26 patients, who carried out dietary therapy with Korean herbal medicine and cultivated wild ginseng pharmacopuncture at Moemfit Clinic, Charmjin Oriental Medicine for 8-12 weeks. And exercise and nutrition were recommended self-developed food, Moemfit Shake, Moemfit Hankki and walking exercise for one hour a day. The body composition values (body weight, body mass index, body fat mass, skeletal muscle mass, waist-hip ratio, visceral fat area, percent body fat) decreased after dietary therapy with Korean herbal medicine and cultivated wild ginseng pharmacopuncture significantly. But, percent skeletal muscle increased significantly. Results from this investigation showed that dietary therapy Korean with herbal medicine and cultivated wild ginseng pharmacopuncture has positive effects on changes of body compositions.

Prevention of Quality Changes in the Cultured Wild Ginseng During Storage (산삼배양근의 저장 중 품질변화 억제)

  • Whang, Jong-Hyun;Yu, Kwang-Won;Park, Sung-Sun;Koh, Jong-Ho;Oh, Sung-Hoon;Suh, Hyung-Joo;Lee, Sang-Hwa
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.37 no.10
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    • pp.1312-1317
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    • 2008
  • Physicochemical changes were investigated for the shelf-life extension of cultured wild-ginseng roots during storage with various pre-treatments with blanching, CAMICA-SD and DF-100 and treatments with citric acid and vitamin C. The pH of cultured wild-ginseng roots showed the range of $6.06{\sim}6.42$ at $10^{\circ}C$, but showed higher ranges of $6.08{\sim}6.91$ and $6.08{\sim}8.68$ at 20 and $30^{\circ}C$, respectively. Browning index (a/b) was increased with increasing storage temperature, and the index at 10 and $30^{\circ}C$ were 0.405 and 0.469 after 2 weeks, respectively. Browning index and viable cell number of CAMICA-SD pre-treatment showed little changes compared to pre-teatment with blanching or DF-100. When the cultured wild-ginseng roots were treated with 1.0% citric acid and 0.2% DF-100 after pre-treatments with CAMICA-SD, viable cell number was slightly increased to $4.9{\times}10^2CFU/g$ for 3 weeks storage at $10^{\circ}C$. The mixture of citric acid and DF-100 was also used to prevent the growth of microbiology and to reduce browning reaction, especially enzymatic browning reaction. The mixture might effectively extend shelf life of the cultured wild-ginseng roots.

Identification study of rare and high-priced natural products used for oriental medicine by RAPD analysis (RAPD 분석법을 이용한 산삼, 웅담, 녹용 등의 한약재 판별연구)

  • Cho, Dong-Wuk
    • Korean Journal of Oriental Medicine
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    • v.1 no.1
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    • pp.471-476
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    • 1995
  • Natural products used for oriental medicine often come from various geographical sources, after several different distribution channels. Therefore some form of quality control procedure is required to safeguard naturl products for prescriptions purposes. To achieve this, systematic apprroaches such as morphological examination, microscopic analysis of powdered herbs and chemical analysis can be carried out. However, to ensure absolute criteria for quality assurance of natural products, DNA fingerprinting method such as RAPD(Random amplified polymorphism DNA) analysis can be used for authentication of natural products for authenticatin of natural products. In this study, warious oligonucleotide primers will be synthesized for the detection of RAPD markers and also parameters of affecting PCR(Polymerase Chain Reaction) in the detection of RAPD markers of rare and high-priced natural products will be studied with genomic DNA of chosen samples.

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The Effect of Cultivated Wild Ginseng Extract on Preadipocyte Proliferation (산양산삼 추출물이 지방세포의 분화에 미치는 영향)

  • Kim, Byoung-Woo;Kwon, Ki-Rok
    • Journal of Pharmacopuncture
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    • v.10 no.3
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    • pp.29-35
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    • 2007
  • Objectives The purpose of this study is to investigate the effects of cultivated wild ginseng extract on primary cultured preadipocyte and adipocytes. Methods Diminish preadipocyte proliferation does primary role to reduce obesity. So, preadipocytes and adipocytes were performed on cell cultures with using Sprague-Dawley rats and treated with 0.01-1mg/ml cultivated wild ginseng extract. Result At all concentrations, cultivated wild ginseng extract wasn't show the suppress proliferation of preadipocytes significantly and failed to show effects on decomposition of adipocytes except high dosage. Conclusion Based on these findings, cultivated wild ginseng is not a suitable choice for the treatment of localized obesity.