• Journal of Digital Convergence
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• v.19 no.5
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• pp.315-320
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• 2021

While blockchain platforms for various purposes have been developed and the blockchain ecosystem is being developed, interoperability problems are emerging in which each blockchain is isolated and operated. In this study, we introduce interchain and sidechain technologies, which are blockchain that connect blockchain, and explain examples of using heterogeneous blockchain transactions and functions by applying them. In addition, blockchain, artificial intelligence, and IoT technologies, which are drawing attention in the fourth industrial revolution, are going through a process of converging and developing beyond their own development. In this regard, we present processes for combining artificial intelligence or IoT in blockchain, and propose a model that can operate without intervention by applying the combination of blockchain and artificial intelligence IoT to processes for trading and exchange between heterogeneous blockchain.

• KIPS Transactions on Computer and Communication Systems
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• v.4 no.1
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• pp.1-4
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• 2015

This paper presents an algorithm for finding valid side chain conformations of amino acids, when given channel is transformed. The suggested algorithm implements a protein molecule with flexible side chains based on the flexibility of amino acids, and extracts adjacent amino acids that affect the formation of the channel. We detect the collision between adjacent amino acids and neighbors, in order to exclude invalid side chain conformations. Then, we construct the rotation angle combination tree to choose valid side chain conformations.

• Proceedings of the Korean Society of Computer Information Conference
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• 2023.07a
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• pp.229-231
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• 2023

최근 대화형 AI와 생성형 AI의 폭발적인 성장과 현실화로 인해, 한 때 온세상을 떠들썩 하게 했던 메타버스와 블록체인 기술은 잊혀지고 있다. 하지만 메타버스는 필연적으로 Web 3.0 시대의 대표적인 플랫폼으로 흘러갈 것이며, 블록체인 기술은 디지털 경제 생태계의 핵심 기술임에 틀림이 없을 것이다. 언제가 될지는 모르지만 다시금 메타버스가 세상을 혁명적으로 변화 시키는 그 때를 염두에 두며, 메타버스 시스템에서 사용되는 블록체인 기술의 현황을 살펴보고 그리 멀지 않은 미래에서의 모습도 전망해 본다.

• Review of KIISC
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• v.34 no.1
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• pp.7-13
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• 2024

블록체인 기술이 발전됨에 따라서 확장성의 보장과 향상을 위한 다양한 기술이 연구 및 개발되고있다. 기존에는 Layer 1에서의 확장성을 주로 연구하는 추세였지만, 현재 Layer 2의 등장으로 인하여, 보다 빠르고 효율적으로 트랜잭션을 처리 및 기록하고, 더 낮은 거래 비용을 제공하는 기술로 발전하였다. 따라서 본 논문에서는 Layer 2 스케일링 솔루션의 최신 동향을 조사하고 현재 기술 개발 사례를 탐색한다. 예를 들어 스테이트 채널, 사이드 체인, 롤업 등을 분석하고, 각 기술의 장단점과 특성을 검토한다. 또한, 이러한 솔루션들이 현재 활용되고 있는 상태와 향후 블록체인 네트워크에서 어떤 역할을 할 수 있는지에 대해 논의한다. 본 논문은 블록체인 네트워크의 확장성과 성능 향상을 위한 접근 방법과 기술적 한계점을 탐색함으로써, 블록체인 기술의 발전 방향과 관련하여 심도높은 이해를 제공한다.

• KSBB Journal
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• v.14 no.3
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• pp.291-296
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• 1999

Chiral epoxides are key intermediates for the production of chiral pharmaceuticals, agrochemicals, and functional food additives. Chiral epoxides can be produced by either chemical or biological method. In biocatalytic production routes, chiral epoxides can be produced via epoxidations of prochiral alkenes by monooxygenase or peroxidase. Kinetic resolution of racemic epoxides using whole cells of bacteria or fungi might be commercially useful, since it is possible to obtain chiral epoxides with high optical purities from relatively cheap and readily avaiable racemic epoxides. Some bioprocesses already are commercially developed: the biocatalytic production of chiral epichlorohydrin via microbial stereospecific dehalogenation, and lipase-catalyzed enantioselective hydrolysis in a hollow fiber membrane bioreactor for the production of chiral methyl trans-3-(4-methoxyphenyl)glycidate. the intermediate for calcium antagonist diltiazem. The importance of biocatalytic production of chiral epoxides with several examples from literature are presented.

• Korean Journal of Food Science and Technology
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• v.17 no.2
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• pp.71-74
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• 1985

In the present study, a tentative mechanism for the decomposition of the hydroperoxide formed during the thermal oxidation of an edible soybean oil was proposed. The soybean oil was thermally oxidized at $120^{\circ}C$ for 7 hrs with air injection at a rate of 120 ml/min. Through kinetic studies of the decomposition process based on the tentative mechanism and the actual experimental data obtained from the hydroperoxide decomposition at 100, 120, 150 and $180^{\circ}C$, it was found that the reaction order of the hydroperoxide decomposition in these conditions was of first order. It was also estimated that the dissociation energy for the hydroperoxide in the same conditions was 15.876 kcal/g. mol.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.20 no.1
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• pp.211-218
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• 2020

Recently, with the advent of blockchain technology, attempts to apply this technology to existing systems are increasing. By using the blockchain technology consensus ledger and smart contract, it is necessary to distribute certificates to various fields that require documents, attestation, authentication, verification, etc. We are studying methods using hash operation, blockchain, etc., but it is difficult to spread the technology as it has not yet reached the stage of commercialization. In this paper, user device registration authentication algorithm, blockchain-based question and answer authentication algorithm, certificate issuance, verification process and encryption algorithm, and server-side authentication for easy application in blockchain based business platform environment We proposed a blockchain-based system authentication method using four algorithms.

• Proceedings of the Korean Vacuum Society Conference
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• 2010.02a
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• pp.234-234
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• 2010

최근 CMOS 소자 크기가 축소됨에 따라 소스와 드레인 영역에서의 접촉저항을 줄이기 위하여, 실리사이드 공정이 많이 연구되고 있다. 실리사이드 물질로서 NiSi는 낮은 저항률과 낮은 실리콘 소모, 낮은 공정온도, 등의 장점을 가지고 있다. 그러나, 실리사이드 형성으로 인한 나노소자의 소오스/드레인에서정션(junction) 누설전류의 증가는 큰 문제가 되므로 실리콘과 실리사이드 계면의 특성이 중요하다. 본 연구에서는 니켈을 이용한 실리사이드 형성시 계면 활성제인 에틸 요오드를 이용하여 실험을 진행하였다. 금속 유기 전구체인 MABONi을 사용하여 ALD 방식으로 증착 한 니켈 박막과 니켈 핵 형성시 계면활성제인 에틸요오드의 처리 방법에 따른 Ni-silicide 박막의 특성을 비교, 분석하였다. 먼저 자연산화막을 건식식각으로 제거한 뒤, 첫 번째 샘플에서는 10회의 주기로 초기 니켈을 증착한 뒤, 에틸요오드로 니켈의 표면 위를 처리하고, 다시 200회의 주기로 니켈을 증착하였으며, 두 번째는 첫 번째 방식에서 에틸요오드 주입 시 동시에 수소도 함께 주입하였다. 세 번째는 비교를 위해 에틸요오드 처리를 하지 않고 니켈 박막만을 증착 하였다. 이어서, 각 샘플을 급속 열처리 장비에서 $400^{\circ}C$부터 $900^{\circ}C$까지 각각 30sec간 열처리를 진행후, 반응하지 않은 잔여 니켈을 제거한 후, XRD(x-ray diffraction), AES(auger), 그리고 4-point probe 등을 이용하여 형성된 실리사이드의 특성을 분석하였다. 에틸요오드와 함께 수소를 주입한 경우 계면에서의 산소 불순물과 카본 성분이 효과적으로 제거되어 $400^{\circ}C$에서 $2.9{\Omega}/{\Box}$ 의 낮은 면저항을 가지는 NiSi가 형성되었고 모든 온도구간에서 다른 샘플에 비하여 가장 낮은 면저항 분포를 보였다. 이는 분해 흡착된 요오드에 의한 계면 특성 향상과 카본 성분이 포함된 잔여물들이 수소처리에 의해 효율적으로 제거되어 실리사이드의 특성이 향상되었기 때문이다. 계면활성제를 사용하지 않은 경우에는 $500^{\circ}C$에서 NiSi가 형성되었다. 반면에 에틸요오드로만 표면을 처리한 경우에는 니켈과 실리콘 계면에서의 카본 성분에 의하여 silicidation 이 충분히 일어나지 않았다. 이러한 결과는 향후 45nm 이하의 CMOS 공정상에서 소스와 드레인의 낮은 누설전류를 가지고, 접촉저항을 줄이기 위한 니켈 실리사이드 형성에 큰 도움을 줄 것으로 기대된다.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.43 no.2
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• pp.157-164
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• 2017

Stevia (Stevia rebaudiana) is a perennial plant of the genus Stevia, originated in South America. It stores many forms of glycosides, mainly stevioside and rebaudioside A, in which steviol is the basic structure. Steviol glycosides, widely used as sweeteners, are superior to sugar in sweetness. Recently, it has been reported that steviol glycosides are involved not only in the skin whitening and anti-inflammatory effect but also in enhancing skin barrier function through tight junction regulation. Thus, we examined anti-inflammatory effect of rebaudioside A and tried to identify its potential for improving atopic dermatitis as cosmetic ingredients. To investigate the anti-inflammatory effect, cell viability and mRNA expression level of inflammation-related cytokines were measured using mouse macrophage RAW264.7 cells. Cell counting kit 8 (CCK-8) assay was carried out to measure cell viability and the maximum concentration without cytotoxicity was set to $250{\mu}M$. A quantitative real-time RT-PCR method was used for the study of the inflammatory suppression of rebaudioside A. Rebaudioside A inhibited expression of inducible nitric oxide synthase (iNOS) up to 47% and COX-2 up to 41% compared to LPS treated condition. NO synthesis was decreased by rebaudioside A. Also, mRNA expression of interleukin (IL)-$1{\alpha}$, IL-$1{\beta}$ and IL-6 in LPS-stimulated RAW264.7 cells was decreased to 40%, 45% and 59%, respectively, as a concentration-dependent manner. In conclusion, rebaudioside A inhibited the inflammatory response by regulation of cytokine gene expression. From these results, we expect that steviol glycoside, such as rebaudioside A, can be used as a material for improving atopic dermatitis in the future.

• Proceedings of the Ginseng society Conference
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• 1988.08a
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• pp.141-146
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• 1988

Dwarf ginseng (Panax trifolius L.) is a member of the ginseng family (Araliaceae). which is indigenous to North America and is distributed from Southern Canada to the Northern United States. In total. nine compounds were isolated from the leaves of Dwarf gineng. Of these. four were identified as flavonoids and five were found to be ginsenosides. Two of the flavonoids were identified to be kaempferol-3. 7-dirhamnoside and kaempferol-3-gluco-7-rhamnoside. Four of the ginsenosides were identified as notoginsenoside-Fe. ginsenoside-Rd. ginsenoside-Rc and $ginsenoside-Rb_1$ The common aglycone of these ginsenosides was shown to be (20S)-protopanaxadiol. The identification of flavonoids and ginsenosides from the root. stem. leaf. flower and fruit of Dwarf ginseng was detected by Two-Dimensional Thin-Layer Chromatography (2D-TLC) and High Performance Liquid Chromatography (HPLC). The quantitation of flavonoids and ginsenosides from the root. stem. leaf. flower and fruit of Dwarf ginseng and related species such as Korean gineng (Panax ginseng C.A. Meyer) and American ginseng (Panax quinquefolium L.) was analyzed by HPLC only. Three flavonoids (Kaempferol derivatives) labelled compound 1 $(10.8\%)$, compound 3 ($2.8\%$), and compound 4 ($8.4\%)$ were found in the root of Dwarf ginseng but not found in the roots of Korean ginseng and American ginseng. This is the first time that flavonoids have been found and identified in roots of the ginseng family (Araliaceae).