• 대한한의학방제학회지
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• 제1권1호
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• pp.87-99
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• 1990

• 한국식품과학회지
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• 제30권4호
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• pp.888-894
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• 1998

한방 보혈제의 기본처방인 사물탕과 보기제의 기본 처방인 사군자탕의 방사선 조사 마우스에서의 방사선 방호 효과를 소장움 생존(고선량 방사선, 12 Gy), 조혈세포 생존(중간선량 방사선, 6.5 Gy), apoptosis 형성(저선량 방사선, 2 Gy) 실험법을 적용하여 관찰하였다. 방사선조사 전 사물탕투여군(경구투여: 음수 mL당 2 mg씩 7일간, 복강내주사: 마리당 1 mg씩 방사선 조사 24시간 전)에서 소장움의 생존이 증가되었으며 (방사선대조군: $38.48{\pm}4.34$, 복강내 주사군: $77.98{\pm}16.11$, P<0.005), endogenous spleen colony의 형성도 높게 나타났고(방사선대조군: $3.5{\pm}4$, 경구투여군: $10.7{\pm}7.730$, 복강내주사군: $8.667{\pm}5.244$, P<0.05), 소장움에서의 apoptotic cell의 발생율은 억제되었다(방사선대조군: $5.111{\pm}0.529$, 복강내주사군 $3.919{\pm}0.214$, P<0.01). 사군자탕 병행투여군에서는 이상의 실험에서 통계적으로 유의성 있는 효과는 없었다. 이상의 결과는 사물탕이 방사선방호 식품으로 활용될 수 있는 가능성을 제시하였으며, 각 구성약재 및 성분의 효과에 대한 연구가 계속되어야 할 것이다.

• 한국가정과학회:학술대회논문집
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• 한국가정과학회 2002년도 학술대회
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• pp.71-71
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• 2002

• 한국식품저장유통학회:학술대회논문집
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• 한국식품저장유통학회 2007년도 학술발표회
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• pp.193-193
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• 2007

• 한국자원식물학회:학술대회논문집
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• 한국자원식물학회 1996년도 International Symposium on the Development of Anti Cancer Resources From Plants및 1996년도 한국자원식물학회 정기학술 발표회
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• pp.72-77
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• 1996

• 혜화의학회지
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• 제20권1호
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• pp.175-182
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• 2011

This study aims to summarize and make a reference of Sagunjatang and Samultang by investigating and comparing the effects of prescriptions. In this process, this review surveyed all papers used Sagunjatang and Samultang in PubMed database and finally 36 papers were included. The publication year, the nations of authors, the type of materials, the formation of experiments, the type of herbal medicine, and their action and mechanisms were analyzed. The number of studies on Sagjunjatang and Samultang has increased since 1990's. The main formation of experiments was in vivo study and the portion was 55%. The proportion of the research using prescriptions was 71%. Sagunjatang was investigated in the field of GI track function, anticancer effect, radioprotective effect and etc. Samultang was studied in the field of anticancer effect, brain cognitive function, anti-inflammatory effect, cell protective effect, and etc. Based on these results, Sagunjatang and Samultang showed the different bioactivities. This study will provide the useful information on differentiation and analysis of the effect of herbal prescriptions by the theory of Korean traditional medicine.

• 동의생리병리학회지
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• 제20권3호
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• pp.634-637
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• 2006

The GC pictures were taken to investigate the difference of the Samul-tang and Sakunja-tang, each prepared by the different boiling methods, which were the traditional method(using cover), using the condenser, and using no cover. For Samul-tang, there was not much difference in the GC pictures, but the one pick(rt about 7 min.) of the picture by the method using the condenser had the higher intensity than those in the pictures by other methods. For Sakunja-tang, the GC pictures of the method using the condenser had shown a lot of the peaks and the very high intensity, which were much better than those of the picture by the traditional method. However, the GC pictures of the method by using no cover had shown almost nothing.

• 동의생리병리학회지
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• 제20권4호
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• pp.942-945
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• 2006

The GC pictures were taken to investigate the difference of Samul-tang and Sakunja-tang from their distillate each. For Samul-tang, it's distillate contained many peaks which had been shown very small peaks in the GC picture of the original solution, but the one pick(rt about 7 min.) of the picture didn't been found in the GC picture of the distillate. For Sakunja-tang, it's distillate contained all peaks which had shown in the GC picture of the original solution. After distillation, there was almost no peak in the rest of the solution.

• 대한한의학원전학회지
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• 제19권1호통권32호
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• pp.47-109
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• 2006

서양의학상인위남녀근근시재생식기부동적인(西洋醫學上認爲男女僅僅是在生殖器不同的人). 최근(最近), Legato, Marianne J.박사창립료(博士創立了)‘성인지의학(性認知醫學)’학(學), 개시인식도남녀적차이(開始認識到男女的差異), 주장남녀재치료방법상역부동법(主張男女在治療方法上亦不同法), 종이저일연구진입도료신적단계(從而這一硏究進入到了新的段階). 단시한의학종(但是韓醫學從)${\ulcorner}$황제내경(黃帝內經)${\lrcorner}$개시(開始), 취인위남녀재구조상유근본적차이(就認爲男女在構造上有根本的差異), 이차재생리(而且在生理), 병리(病理), 진단(診斷), 치료상야부동(治療上也不同). 기록한의학기본원리적주역적상관서적화(記錄韓醫學基本原理的周易的相關書籍和)${\ulcorner}$황제내경(黃帝內經)${\lrcorner}$, 이급역대적주요한의서적급종사임상적한의사적서적상(以及歷代的主要韓醫書籍及從事臨床的韓醫師的書籍上), 역도인위남녀유차이(亦都認爲男女有差異). 관어남녀적생성(關於男女的生成), 재(在)${\ulcorner}$보제방(普濟方) 방맥총론(方脈總論)${\lrcorner}$적변남녀형생신육론중제출료(的辨男女形生神毓論中提出了男女的形成有異). ${\ulcorner}$동의보감(東醫寶鑑)${\lrcorner}$여기타한의서부동(與其他韓醫書不同), 불시이질병위주(不是以疾病爲主), 이시이신위중심(而是以身爲中心), 즉목차안형상진행료배열(卽目次按形象進行了排列), 차상세지언급료남녀(且詳細地言及了男女). 나요남녀시고정불변적마 불시적(不是的). ${\ulcorner}$동의보감(東醫寶鑑) 신형장부론(身形臟腑論)${\lrcorner}$인위(認爲)‘인적형색유차이(人的形色有差異), 장부이유이(臟腑易有異), 고외증수동(故外症雖同), 치법인인이이(治法因人而異).’ 안형상선용부동적치법적관점(按形象選用不同的治法的觀点), 이통과주단계지언이표명(已通過朱丹溪之言而表明). 불변관점상여자체격소이동(不變觀点上女子體格小易動), 남자체격대이와(男子體格大易臥). 남자속양기이산(男子屬陽氣易散). 여남자정서초차(如男子情緖稍差), 즉음주해수(卽飮酒解愁), 불이득우울증(不易得憂鬱症). 응보기정기(應補其精氣). 여자속음기이울체(女子屬陰氣易鬱滯), 다유인기지성질(多有忍氣之性質), 이득우울증(易得憂鬱症), 고다용산기약(故多用散氣藥). 간단이언(簡單而言)‘남자위병허증(男子爲病虛證), 여자위병실증(女子爲病實證).’ 종변화적관점래용약(從變化的觀点來用藥), 예여남자수소가용여자약적사물탕(例如男子瘦小可用女子藥的四物湯). 여자비가용남자약적사군자탕(女子肥可用男子藥的四君子湯). 여자골장가용남자약적육미지황환(女子骨壯可用男子藥的六味地黃丸). 위료갱용역이해(爲了更容易理解)‘남녀불변화변화적관점재의학적운용(男女不變和變化的觀点在醫學的運用)’, 이임상병례진행설명(以臨床病例進行說明). 재임상상통과형색맥증적합일화변증론치결정처방(在臨床上通過形色脈證的合一和辨證論治決定處方). 즉불능단순적인위(卽不能單純的認爲), 인위시남자취용육미지황환(因爲是男子就用六味地黃丸), 여자취용사물탕(女子就用四物湯). 남자약소가용사군자탕(男子若小可用四君子湯) 사물탕(四物湯) 육미지황탕(六味地黃湯), 이여자약대가용사군자탕(而女子若大可用四君子湯) 이진탕(二陳湯) 평위산(平胃散) 육군자탕(六君子湯). 인차(因此) 남녀재구조(男女在構造) 생리(生理) 병리유근본성차이(病理有根本性差異), 불이형상래구분(不以形象來區分), 용약상시지불변적입장(用藥上是持不變的立場), 이이형상용약(而以形象用藥), 시종변화적입장래고려적(是從變化的立場來考慮的). 인위이남녀위기준종사임상(認爲以男女爲基準從事臨床), 시부합한의학기본원리지음양관(是符合韓醫學基本原理之陰陽觀).

• 혜화의학회지
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• 제8권1호
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• pp.837-851
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• 1999

In order to inverstigate interactive effects of Samultang(SMT) and SMT composition and the principle of prescription, I examined the effects of SMT and combination of three components of SMT, In C57BL/6 mouse with oral administration of SMT and cyclophosphamide(CTX) treatment, white blood cells, platelet were counted. Also, those were anti-anemia effect for rat which have hemolytic anemia induced by phenylhydrazine. The results were summerized as follows : 1. In vivo analysis of the effect of the SMT by orally administrated C57BL/6 mice with the SMT and was treated with cyclophosphamide (CTX). When the number of white blood cell. platelet was counted, there was ameliorative effects of leucopenia or thrombocytopenia as a protection to CTX. 2. It was acknowledged that SMT and its composition increased RBC count and hemlytic significantly in rat which have hemolytic anemia. 3. Among SMT composition Angelicae gigantis Radix and Cnidii Rhizoma solution and among the combination group Rehmanniae Radix and Cnidii Rhizoma combination and SMT solution showed significant effects for hemoglobin and weight of spleen in mouse which have hemolytic anemia. Thus it was acknowledged that Rehmanniae Radix and Cnidii Rhizoma combination had effect to improve hemoglobin and weight of spleen. From above these results it was acknowledged that SMT has effects that ameliorative effects of leucopenia or thrombocytopenia as a protection to CTX and anti-anemic effect for the rat which have hemolytic anemia induced by phenylhydrazine and these effects depend upon its combination of SMT composition. Especially it was acknowleged, though there are the slight difference according to combination, that Paeoniae Radix Alba combination had improving effect for physical change. So it is though that Paeoniae Radix Alba is main material for this kind of disease and continuous study is needed.