• The Korean Journal of Nuclear Medicine
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• v.34 no.3
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• pp.183-198
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• 2000

Purpose: The purpose of this study was to evaluate alterations of regional cerebral blood flow (CBF) and cerebrovascular reserve (CVR), and correlation between these alternations and cognitive dysfunction in patients with chronic traumatic brain injury (TBI) and normal brain MRI findings. Materials and Methods: Thirty TBI patients and 19 healthy volunteers underwent rest/acetazolamide brain SPECT using Tc-99m HMPAO. Korean-Wechsler Adult Intelligence scale test was also performed in the patient group. Statistical analysis was performed with statistical parametric mapping software (SPM'97) Results: CBF was diminished in the left hemisphere including Wernicke's area in all patients with lower verbal scale scores. In addition, a reduction in CBF in the right frontal, temporal and parietal cortices was related with depressed scores in information, digital span, arithmetic and similarities. In patients with lower performance scale scores, CBF was mainly diminished in the right hemisphere including superior temporal and supramarginal gyri, premotor, primary somatomotor and a part of prefrontal cortices, left frontal lobe and supramarginal gyrus. CVR was diminished in sixty-four Brodmann's areas compared to control. A reduction in CVR was demonstrated bilaterally in the frontal and temporal lobes in patients with lower scores in both verbal and performance tests, and in addition, both inferior parietal and occipital lobes in information subset. Conclusion: Alterations of CBF and CVR were demonstrated in the symptomatic TBI patients with normal MRI finding. These alterations were correlated with the change of intelligence, of which the complex functions are subserved by multiple interconnected cortical structures.

• Journal of Life Science
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• v.28 no.10
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• pp.1233-1243
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• 2018

Sterol regulatory-element binding proteins (SREBPs) are a family of transcription factors that regulate lipid homeostasis and metabolism by controlling the expression of enzymes required for endogenous cholesterol, fatty acid (FA), triacylglycerol, and phospholipid synthesis. The three SREBPs are encoded by two different genes. The SREBP1 gene gives rise to SREBP-1a and SREBP-1c, which are derived from utilization of alternate promoters that yield transcripts in which distinct first exons are spliced to a common second exon. SREBP-2 is derived from a separate gene. Additionally, SREBPs are implicated in numerous pathogenic processes, such as endoplasmic reticulum stress, inflammation, autophagy, and apoptosis. They also contribute to obesity, dyslipidemia, diabetes mellitus, and nonalcoholic fatty liver diseases. Genome-wide analyses have revealed that these versatile transcription factors act as important nodes of biological signaling networks. Changes in cell metabolism and growth are reciprocally linked through SREBPs. Anabolic and growth signaling pathways branch off and connect to multiple steps of SREBP activation and form complex regulatory networks. SREBPs are activated through the PI3K-Akt-mTOR pathway in these processes, but the molecular mechanism remains to be understood. This review aims to provide a comprehensive understanding of the role of SREBPs in physiology and pathophysiology at the cell, organ, and organism levels.

• Korean Journal of Social Welfare
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• v.52
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• pp.201-221
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• 2003

This paper aims to examine whether there are significant differences in various aspects of a household's arrangements by type of employment of married woman; 1) the extent of the division of labor, 2) the authority of decision making, and 3) financial and expenditure responsibilities. It also investigates the determinants of gender equality in the family. Based on data collected in the fall of 2002 from a representative sample of the Korean population, this study finds that nonstandard employment of married woman including temporary work and daily basis work does not contribute to gender equality within the household, although most of nonstandard employees are full-time workers. However, standard employment of married woman contribute to gender equality in the family. The results of this study show that husbands whose wives are standard-employed are more likely to take part in housework chores that are female-dominated, and standardly employed wives are more likely than non-standardly employed or housewives to take part in the household's financial and expenditure responsibilities. Standardly employed wives also have more power in decision making process within households. On the contrary, non-standardly employed wives gain no advantage over housewives within their families, due to lack of bargaining resources that enable them to affect the household's arrangements. Thus, they have confronted additional burdens, which stem from carrying the dual role of doing house work as well as paid work. Such increasing work-family conflict may bring about disruption of family. Therefore, this study maintains that it is high time that government-level efforts should be made in order to improve the status of irregularly employed wives in the workplace.

• Journal of Korea Entertainment Industry Association
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• v.15 no.4
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• pp.299-307
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• 2021

This study is a research study to identify the recognition, experiences, needs of convergence education in occupational therapy students. Therefore, it is intended to provide basic data when developing convergence subjects and non-regular programs within the occupational therapy (department) curriculum. From December 03, 2020, a web questionnaire consisting of 14 questions in 4 areas was distributed over a month, and the data of 130 people were finally analyzed. The results are as follows. First, the recognition and experiences of occupational therapy students in convergence education were low. Second, 57.7% of students recognized that occupational therapy majors need convergence education, and the expected effect of convergence education was 'improvement of occupational therapy job-related knowledge'. Third, it was recognized that 'natural science', 'prosthesis and assistive technology, activity of daily living(ADL)', and 'ADL training' convergence education was necessary for the students of occupational therapy department. The results of this study are expected to be used as basic data in the future development of occupational therapy curriculum and non-regular programs for convergence education. In the future, I think that the demand for convergence education and program development in preparation for the 4th industrial revolution will increase in the occupational therapy curriculum. It is expected that the data of this study will be used meaningfully by professors in charge of occupational therapy education at universities.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.46 no.6
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• pp.11-18
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• 2009

In this paper, a hierarchical link allocation algorithm between mobile stations (MSs) and the corresponding base station (BS) by an optimal utilization of relay stations (RSs) is proposed to improve throughput of RS systems. In the proposed hierarchical algorithm, each RS operates cognitive radio functions to sense the degree of satisfaction in the quality of services (QoSs) and then selects the candidate set of MSs to have links with the RS. Such information is reported to the BS, where an auction process is performed to get an optimal allocation of communication links between the MSs and the BS. To maximize system throughput, the proposed auction algorithm is conducted upon bidding prices of communication links, considering both the co-channel interference (CCI) information shared among adjacent cells and the QoS enhancement information for each MS collected from RSs. The BS then switches the communication links of the auction winner MSs through the corresponding RS. The computer simulation shows that the proposed algorithm enhances the user QoS more than the conventional algorithm, especially for RS systems with more users requiring higher QoS. The proposed algorithm has also been proved to have more robust performance than the conventional one when the traffic load is higher and the CCI becomes stronger.

• Journal of Radiation Protection and Research
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• v.41 no.1
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• pp.15-29
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• 2016

Research background: Despite the visible growth in radiation usage and nuclear power development, the analysis of their relationship with fundamental rights, a subject of public concern regarding issues including the right to health, environmental rights, safety rights, the right to know, the right to development, and the right to life, is currently non-existent. Methods: By examining various fundamental rights in the context of positive laws regarding radiation and nuclear power in an idealistic perspective that guarantees the maximum degree of rights, this paper aims to propose legislative supplements that will lead to improvements in quality of life. Result and discussion: In the South Korean Constitution, radiation and nuclear power is a subject incorporating several rights, including at least 12 clauses that are directly related to fundamental rights; these constitutional rights are manifested in the various clauses of the 14 positive laws regarding radiation and nuclear power. The question on the relative importance of each fundamental right as reflected in these positive laws- whether the right to life should be prioritized or considered equal in weight to the right to health, environmental rights, the right to know, and safety rights- requires careful deliberation and is difficult to humanly resolve in the short term. Conclusion: Making policy that expands the usage of radiation and nuclear power while simultaneously preventing their associated risks is an important task for the Republic of Korea, and a proper value judgment is necessary to find a balance in its associated rights.

• Spatial Information Research
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• v.22 no.1
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• pp.75-84
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• 2014

Power lines are one of the main obstacles causing an aircraft crash and thus their realtime detection is significantly important during flight. To avoid such flight obstacles, the use of LIDAR has been recently increasing thanks to its advantages that it is less sensitive to weather conditions and can operate in day and night. In this study, we suggest a fast method to detect power lines from LIDAR data for flight obstacle avoidance. The proposed method first extracts non-ground points by eliminating the points reflected from ground surfaces using a filtering process. Second, we calculate the eigenvalues for the covariance matrix from the coordinates of the generated non-ground points and obtain the ratio of eigenvalues. Based on the ratio of eigenvalues, we can classify the points on a linear structure. Finally, among them, we select the points forming horizontally long straight as power-line points. To verify the algorithm, we used both real and simulated data as the input data. From the experimental results, it is shown that the average detection rate and time are 80% and 0.2 second, respectively. If we would improve the method based on the experiment results from the various flight scenario, it will be effectively utilized for a flight obstacle avoidance system.

• Korean Journal of Construction Engineering and Management
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• v.14 no.3
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• pp.123-133
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• 2013

Green infrastructure projects have the potential to reduce global warming and deliver sustainable energy solutions. Recently, the construction industry has been expanding their portfolios in New and Renewable (NRE) projects. However, the economic feasibility of NRE projects have not been validated and construction companies are not acquainted with their associated risks. This research performed a two-tiered feasibility study of the domestic projects registered for CDM in the UNFCCC. The first phase involved calculating the average IRR and NPV of the domestic CDM projects, which showed that their profitability to be very low. In the second phase, four NRE projects (Solar, Wind, Hydro, Landfill Gas) were selected and additional income generated from Feed-in-Tariff and CER sales were added to determine the improvements in the projects' IRR and NPV. Results indicate that Solar and Landfill Gas projects benefited the most from the two support mechanisms, while benefits to Wind and Hydro projects were minimal. While the Landfill Gas project had the highest IRR, the Wind project was the most investment attractive due to its NPV and minimal dependency on FiT and CER sales. Construction companies should enter into NRE projects with a long term view as related technologies mature.

• Journal of vocational education research
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• v.30 no.4
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• pp.161-177
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• 2011

The major purpose of this study is to see the effects of medical students' self-regulated learning on career adaptability. Therefore, we carried out self-regulated learning and career adaptability tests for the 252 medical students belong to the K university to examine the above subject. Then the respondents were divided into two groups according to the level of career adaptability to see the group differences on self-regulated learning. The results of this research are as follows. The group of high career adaptability was scored higher than the lower scored group in every domains of self-regulated learning except test anxiety. And also the result of regression analysis to see the effects of self-regulated learning on sub-domains of the career adaptability like responsibility, interpersonal relationship, proactivity, positive attitude showed statistically significant differences to the total score of career adaptability except motivation controlling. Based on the above results, this study suggest the need of mediation related with self-regulation, and also the need of counselling and education to help the medical students suffering from adaptability. Furthermore, suggest following studies searching the multiple variables affecting career adaptability.

• Journal of the Korean Chemical Society
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• v.48 no.3
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• pp.283-290
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• 2004

The purpose of this study were to develop of courseware using scaffolding strategy and to investigate the effect of courseware instruction upon students' conceptual understanding and affective domain including effort and self-checking. 10th grade students in the experimental and control groups were selected from high school at Cheongwon-gun in Chungbuk, and taught about chemical reaction rate for 3 class hours. The students in the experimental group studied individually through courseware using scaffolding strategy and worksheet and teacher-centered expository lesson was used in the control group. Prior to the instructions, test specification for problem-solving assessment (TSPSA) was administered and the scores of the previous science achievement test were obtained. After the instructions, the posttest on conceptual understanding and TSPSA were administered. Results of this study revealed that the mean score of the experimental group in the conceptual understanding test was similar to that of the control group at statistically significant level. This result implies that the courseware using scaffolding strategy could be a tool of the individualized instruction. The experimental group improved significantly better in three components of the TSPSA such as effort, self-checking, and cognitive strategy. From this result, it is considered that learners' self regulation is improved by being taken over responsibility of learning. So, it is suggested that instruction using scaffolding strategy is needed in science class to improve self-leading learning ability.