• Food Science and Preservation
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• v.20 no.1
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• pp.1-6
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• 2013

In this study, the effect of Curcuma longa L. on obesity and insulin resistance was investigated in animals fed a moderate high fat diet. The animals used in this study were normal weight Spargue-Dawley (SD) rats and type 2 diabetic obese db/db mice. Accumulation of abdominal adipose tissue and weight gain were inhibited in the animals fed the C. longa extract. C. longa decreased fasting insulin and HOMA-IR in the SD rats, and effectively decreased blood glucose and hemoglobin A1c in db/db mice. C. longa decreased serum free fatty acid (FFA) level in the SD rats. FFA in db/db mice fed C. longa tended to decrease. C. longa significantly decreased serum triglyceride level. Our results collectively represent that C. longa prevented fat accumulation and insulin resistance in both normal weight SD rats and type 2 diabetic obese db/db mice fed a moderate high fat diet.

• Journal of Nutrition and Health
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• v.51 no.1
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• pp.14-22
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• 2018

Purpose: Colorectal cancer, which is one of the most commonly diagnosed cancers in developing and developed countries, is highly associated with obesity. The association is largely attributed to changes to western style diets in those countries containing high-fat and high-energy. Luteolin (LUT) is a known potent inhibitor of inflammation, obesity, and cancer. In this study, we investigated the effects of LUT on chemical-induced colon carcinogenesis in high fat diet (HFD)-fed obese mice. Methods: Five-week-old male C57BL/6 mice received a single intraperitoneal injection of azoxymethane (AOM) at a dose of 12.5 mg/kg body weight. Mice were then divided into four groups (n = 10) that received one of the following diets for 11 weeks after the AOM injection: normal diet (ND); HFD; HFD with 0.0025% LUT (HFD LL); HFD with 0.005% LUT (HFD HL). One week after AOM injection, animals received 1~2% dextran sodium sulfate in their drinking water over three cycles consisting of five consecutive days each that were separated by 16 days. Results: Body weight, ratio of colon weight/length, and tumor multiplicity increased significantly in the HFD group compared to the ND group. Luteolin supplementation of the HFD significantly reduced the ratio of colon weight/length and colon tumors, but not body weight. The levels of plasma $TNF-{\alpha}$ and colonic expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 protein increased in response to HFD, but were suppressed by LUT supplementation. Immunohistochemistry analysis also showed that iNOS expression was decreased by LUT. Conclusion: Consumption of LUT may reduce the risk of obesity-associated colorectal cancer by suppression of colonic inflammation.

• Journal of the Korean Home Economics Association
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• v.45 no.4
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• pp.113-122
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• 2007

The purpose of this study was to investigate weight control and the relative influence of individual variables affecting children's attempts to control weight. The study subjects were 319 elementary school children. First, the average body height and weight of the children who participated in this study was somewhat larger in boys and similar in girls, as compared with the normal body shape of Korean children. More boys were classified as overweight than girls, based on BMI. Both boys and girls were dissatisfied with their body shape, and especially the girls showed higher dissatisfaction rate than the boys did. Almost half of the children were concerned about weight control and girls had higher concern than boys. Of the children, 38.8% had controlled their weight; however there was no difference between their sexes. There were significant differences between children who had and had not experienced weight control in the following variables: stress caused by obesity, body satisfaction, BMI, subjective body shape perception and concern about weight control. Therefore, discriminant function analysis was performed to determine the discrimination of these variables between the two groups. From the analysis results, the most critical factor was BMI in the boys and concern about weight control in the girls. This finding should be reflected in the design of weight control programs for children i.e., boys should be encouraged to perceive correctly their own body shape and to control weight by maintaining a well-balanced diet and moderate exercise over a long period of time, rather than by skipping meals, while girls should be inspired with sound values and attitudes regarding their body shape, rather than provided with the concrete information on how to control weight.

• The Korean Journal of Food And Nutrition
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• v.13 no.2
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• pp.125-133
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• 2000

The purpose of this study was to investigate eating behavior, nutritional status and health condition of obese adult attending a weight control exercise. The subjects of this study consisted of 81 adult in some areas of Daegu. Their weight, height, triceps, midarm circumference were measured and their dietary intake and eating behavior were obtained by using questionnaires. Anthropometry was conducted to determine obesity. Average age of men and women were 38.1 and 35.2 years old respectively. Their intake of energy and protein were 69.5% and 97.4% of RDA respectively. Energy intake of normal and obese group was 74.4% and 64.9% of RDA respectively. Protein intake of normal and obese group was 99.7% and 95.3% of RDA respectively There was a negative correlation between PIBW and energy intake, PIBW and carbohydrate intake, BMI and energy intake, and BMI and carbohydrate intake. A relative magnitude of factors affecting weight decrease rate was analyzed by Stepwise multiple regression analysis. Overall results about relative influence of independent variables to dependent variable(weight decrease rate) indicated that the BMI(p<0.01) was the most significantly correlated with weight decrease rate in all subjects. The results of this study suggest that the extensive nutrition education in weight control program should be emphasized to prevent obesity early.

• Journal of the Korean Society of Food Culture
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• v.30 no.6
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• pp.825-833
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• 2015

This study was conducted to investigate the effectiveness of a nutrition and exercise education program on weight control and nutrition knowledge. The nutrition-exercise educational period was 12 weeks. The subjects were 160 adult women with an average age of 48.1 years. We investigated general characteristics, diet history, eating habits, and intake frequencies of six food groups by survey. A total of 94 women among the subjects participated in the pre and post nutrition knowledge evaluations and anthropometric data assessment. After the program, body weight, body mass index (BMI), and waist circumference significantly decreased. Further, % of body fat decreased, but not significantly. BMI significantly decreased (p<0.001) from 25.14 to $24.80kg/m^2$, and waist circumference significantly decreased (p<0.001) from 79.72 to 77.63 cm. The nutrition knowledge scores of subjects significantly increased (p<0.001) from 8.01 to 9.03. However, there was little change in employment. These results suggest that the nutrition-exercise education program may improve obesity index and nutrition knowledge. However, it is necessary to develop a specialized weight control program for workers.

• Korean Journal of Community Nutrition
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• v.14 no.6
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• pp.756-766
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• 2009

This study was conducted to investigate the effects of weight control program on nutrient intakes and physical fitness of Korean obese adult women. The subjects of this study were 33 obese adult women aged 30-65 years residing in Seoul. The weight control program for obese women included nutrition education, cognitive behavioral therapy and exercise for 12 weeks. There were significant decrease (p < 0.001) of blood pressure and atherogenic index of obese women after the weight control program. Energy intake was significantly decreased (p < 0.001) from 1556.9kcal to 1044.9kcal after 12 weeks of the weight control program. Also protein, fat and carbohydrate intakes were significantly decreased. The ratio of energy intakes per day for the subjects was carbohydrate 64% : protein 16% : fat 20%. The frequency of vegetables intakes was significantly increased (p < 0.05) and there were no significant differences in other food groups. After the weight control program, muscle endurance, flexibility, balance and explosive muscular strength of subject's physical fitness were significantly improved. These results suggest that the weight control program for obese women may contribute to nutrient intakes reduction and improvement of physical fitness.

• Child Health Nursing Research
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• v.19 no.3
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• pp.187-197
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• 2013

Purpose: The purpose of the study was to develop an emotional self-regulation program for obese children and to examine the program's effectiveness on depression, eating habits, and body mass index. Methods: The emotional self-regulation program was developed from theory-based strategies and a pre-post pilot study was conducted with 46 children (19: intervention, 27: control). The program included 6 weekly group sessions over 2 months. The embedded experimental model of concurrent mixed methods was used to better understand research outcomes by converging both quantitative and qualitative data. Anthropometric measurements and surveys were performed before and after the intervention. Three focus group interviews were conducted with all participants after intervention to explore their experiences. Results: The intervention group displayed decreased depression levels in the quantitative outcomes. The participants also expressed positive outcomes such as improvements in confidence, impulse management, intimacy, happiness, and losing weight. Conclusion: These findings suggest that emotional self-regulation skills are crucial factors for obese children not only to manage their emotional problems but also to control their weight. Further research is needed with a larger sample size and randomized controlled trials.

• The Journal of Korean Medicine
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• v.43 no.3
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• pp.65-78
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• 2022

Objectives: The purpose of this study is to analyze the weight loss and the adverse events of overweight and obese adults on weight loss program with face-to-face treatment (FTF) and non-face-to-face treatment (NFTF) in 6 Korean Medicine obesity clinics. Methods: From March 2nd to March 10th, 2021, we collected data with a retrospective way from overweight and obese adults (body mass index, BMI≥23 kg/m²) who registered for a 12-week Gamitaeeumjowi-tang prescription program. After matching initial information of the FTF group and the NFTF group using propensity matching score, weight loss and BMI change were analyzed, and adverse events were evaluated in terms of causality, severity and system-organ classes. Results: Weight and BMI change from baseline to 12 weeks was -7.98±3.09kg (10.41±3.57%), -3.03±1.14kg/m² and -7.30±3.11kg (9.59±3.45%), -2.76±1.15kg/m² for FTF group and NFTF group, respectively. Body weight and BMI significantly decreased before and after treatment in both groups, and there was no significant difference in weight loss and BMI change between the two groups. No serious adverse events were reported. Conclusions: This study showed the potential that NFTF weight management treatment could be a good alternative way to FTF weight management treatment without serious adverse events.

• Journal of the Korean Society of Food Science and Nutrition
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• v.46 no.2
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• pp.153-160
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• 2017

Data are limited on biological mechanisms underlying the associations of sleep insufficiency with obesity and dyslipidemia. To explore these mechanisms, we investigated appetite-regulating hormones, stress-related hormones, and cardiometabolic indicators in association with sleep fragmentation, which is a type of sleep disorder. In an experimental study, we randomly allocated 40 Wistar male rats aged 7 weeks into four groups; rats with ad libitum sleep and ad libitum intake (Control), those exposed to sleep fragmentation (SF), those with diet restriction (DR), and those exposed to sleep fragmentation and diet restriction (SF+DR). Amongst them, 13-day chronic sleep fragmentation was applied to the SF and SF+DR groups while 50% reduction in chow intake was applied to the DR and SF+DR groups for 13 days. After these experiments, blood lipid and lipoprotein profiles, leptin, ghrelin, adiponectin, cortisol, epinephrine, and norepinephrine levels were compared among the four groups. In the results, the SF group showed the highest levels of serum ghrelin (P<0.001) and the lowest levels of serum adiponectin (P<0.01). All experimental groups showed higher levels of low density lipoprotein-cholesterol (LDL-C) than the Control (P<0.001). LDL-C levels and the ratio of LDL-C and high density lipoprotein-cholesterol were positively correlated with ghrelin levels (P<0.05) in the SF group, but not in the DR and SF+DR groups. In the SF group, the highest levels of serum free fatty acids were also observed and correlated with lower levels of serum adiponectin, which reflects insulin resistance (P<0.05). Based on these findings, we suggest that chronic sleep fragmentation may induce disturbances in lipid metabolism and appetite-regulating hormones independent of food intake, and these metabolic disturbances may be worse due to insulin resistance related to overeating, which is indicated by elevated ghrelin levels in sleep fragmentation. For persons with sleep insufficiency, anti-atherogenic dietary interventions may be recommended to prevent cardiovascular disease.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.13 no.10
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• pp.4636-4644
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• 2012

The purpose of this study was to analyze the effects of line dance exercise on HOMA-IR and energy metabolic factors in postmenopausal obese women. The subjects were 24 obese women composed of the line dance group(n=12) trained for 12-week and the control group(n=12). The variables of body composition, HOMA-IR and energy metabolic factors were measured in all the subjects before and after the 12-week line dance exercise. The results of the study in the line dance group were as follows; The body weight, %fat, BMI, WHR and VFA had significantly decreased, but LBM had increased. The ghrelin, HDL-C had significantly increased, but leptin, insulin, glucose, HOMA-IR, TC, TG, LDL-C, SBP and DBP had decreased. And ghrelin, leptin, insulin, and glucose were the energy metabolic factors affecting the HOMA-IR in the line dance group. Therefore, regular and continuous line dance exercise will be effective for preventing the life-style diseases with improvement of the energy metabolic factors and insulin resistance by decreasing the body fat.