The Journal of Korean Medicine (대한한의학회지)

The Society of Korean Medicine (대한한의학회)
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Analysis of Weight Loss and Adverse Events in Overweight, and Obese Patients on Korean Medicine Weight Management Program with Face-to-Face Treatment and Non-Face-to-Face Treatment: A Retrospective Chart Review

대면 및 비대면 한의 체중조절 프로그램에 참여한 과체중, 비만 환자에서의 체중감량 및 이상반응 비교 분석: 후향적 차트 리뷰

  • Received : 2022.06.10
  • Accepted : 2022.08.16
  • Published : 2022.09.01
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Abstract

Objectives: The purpose of this study is to analyze the weight loss and the adverse events of overweight and obese adults on weight loss program with face-to-face treatment (FTF) and non-face-to-face treatment (NFTF) in 6 Korean Medicine obesity clinics. Methods: From March 2nd to March 10th, 2021, we collected data with a retrospective way from overweight and obese adults (body mass index, BMI≥23 kg/m2) who registered for a 12-week Gamitaeeumjowi-tang prescription program. After matching initial information of the FTF group and the NFTF group using propensity matching score, weight loss and BMI change were analyzed, and adverse events were evaluated in terms of causality, severity and system-organ classes. Results: Weight and BMI change from baseline to 12 weeks was -7.98±3.09kg (10.41±3.57%), -3.03±1.14kg/m2 and -7.30±3.11kg (9.59±3.45%), -2.76±1.15kg/m2 for FTF group and NFTF group, respectively. Body weight and BMI significantly decreased before and after treatment in both groups, and there was no significant difference in weight loss and BMI change between the two groups. No serious adverse events were reported. Conclusions: This study showed the potential that NFTF weight management treatment could be a good alternative way to FTF weight management treatment without serious adverse events.

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References

  1. World Health Organization, Telemedicine: opportunities and developments in member states. Report on the second global survey on eHealth., 2010
  2. Lee, J. (2020). The recent trends in telemedicine in the era of COVID-19 and policy recommendations for the balanced growth of healthcare service industry in Korea. JCCT, 6(4), 591-598. DOI :https://doi.org/10.17703/JCCT.2020.6.4.591
  3. Baek, K. (2020). A study on telemedicine in the United States: focusing on implications for countermeasures about COVID-19. Kyungpook Natl. Univ. Law Journal, 70, 363-386. DOI :10.17248/knulaw..70.202007.363
  4. Wall, K.C., Politzer, C.S., Chahla, J., Garrigues, G.E. (2020). Obesity is associated with an increased prevalence of glenohumeral osteoarthritis and arthroplasty: A cohort study. Orthop Clin N Am, 51(2), 259-264. DOI: 10.1016/j.ocl.2019.12.001
  5. Kolb, R., Sutterwala, F.S., Zhang, W. (2016). Obesity and cancer: inflammation bridges the two. Curr Opin Pharmacol, 29, 77-89. DOI:10.1016/j.coph.2016.07.005
  6. Zhou, Y., Chi, J., Lv, W., Wang, Y. (2021). Obesity and diabetes as high-risk factors for severe coronavirus disease 2019 (Covid-19). Diabetes Metab Res Rev, 37(2), e3377. doi:10.1002/dmrr.3377.
  7. Won, S., Lee, M., Moon, S., Jung, H., Ki, J., Park, S., et al. (2021). The necessity of analyzing the effectiveness of temporary non-face-to-face treatment. 2021 Analysis of National Assembly Audit Issues, 9, 37-38.
  8. Lee, A., Lee, D., Kim, M., Lee, H., Choi, K., Kim, S., et al. (2021). Gamitaeeumjowee-tang for weight loss in diabetic patients: A retrospective chart review. J Korean Med, 42(1), 46-58. DOI: https://doi.org/10.13048/jkm.21004
  9. Kang, E., Park, Y., Kim, M., Park, Y. (2017). A Study on Factors Associated with Weight Loss by 'Gamitaeeumjowee-Tang'. J Korean Med Obes Res, 17(2), 68-72. DOI : https://doi.org/10.15429/jkomor.2017.17.2.68
  10. Yoon, N., Yoo, Y., Kim, M., Kim, S., Lim, Y., Lim, H., et al. (2018). Analysis of adverse events in weight loss program in combination with 'Gamitaeeumjowee-tang' and low-calorie diet. J Korean Med Obes Res, 18(1), 1-9. DOI: https://doi.org/10.15429/jkomor.2018.18.1.1
  11. Park, Y., Cominguez, D., Kim, H., Jin, J., Koh, D., Kim, S., et al. (2021). Therapeutic effects of Gambi-jung for the treatment of obesity. Biomed Pharmacother, 141, 111838. DOI: 10.1016/j.biopha.2021.111838
  12. Lee, E., Park, Y., Lim, Y., Kim, S. (2020). The association between sleep and weight loss among adult women with obesity administered with Gamitaeeumjowee-tang. J Korean Med, 41(3), 22-31. DOI : https://doi.org/10.13048/jkm.20023
  13. Korea Institute of Drug Safety & Risk Reaction Management. Adverse Drug Assessment Report. 1st ed. Seoul: Korea Institute of Drug Safety & Risk Management. 2013:60-3.
  14. National Cancer Institute. National Institute of Health. U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES. Common Terminology Criteria for Adverse Events (CTCAE) Version 4.0. 2010.
  15. Korea Institute of Drug Safety & Risk Management. Terminology Guide for Reporting Adverse Drug Reactions. Seoul: Korea Institute of Drug Safety & Risk Management. 2014:1-6.
  16. Kim, E., Lim, Y., Park, Y., Kang, J., Kim, S. (2022). Prediction of initial average weight loss in overweight and obese people taking Gamitaeeumjowi-tang. Korean J Subhealth Med, 3(1), 13-22. DOI :https://doi.org/10.37928/kjsm.2022.3.1.13
  17. Han, J., Park, Y. (2019). Analysis of Factors Influencing Obesity Treatment according to Initial Condition and Compliance with Medication. J Korean Med Obes Res, 19(1), 31-41. DOI : https://doi.org/10.15429/jkomor.2019.19.1.31
  18. Choi, Y. (2020). A study on the introduction of telemedicine -Coronavirus disease 2019 and the need for the introduction of telemedicine-. International law review, 12(1), 113-137. DOI: 10.36727/jjilr.12.1.202005.005
  19. Fleischman, A., Hourigan, S.E., Lyon, H.N., Landry, M.G., Reynolds, J., Steltz, S.K., et al. (2016). Creating an integrated care model for childhood obesity: a randomized pilot study utilizing telehealth in a community primary care setting. Clin Obes, 6(6), 380-388. doi:10.1111/cob.12166.
  20. Perri, M.G., Shankar, M.N., Daniels, M.J., Durning, P.E., Ross, K.M., Limacher, M.C., et al. (2020). Effect of telehealth extended care for maintenance of weight loss in rural US communities: a randomized clinical trial. JAMANetwOpen, 3(6), e206764. doi: 10.1001/jamanetworkopen.2020.6764.
  21. Johnson, K.E., Alencar, M.K., Coakley, K.E., Swift, D.L., Cole, N.H., Mermier, C.M., et al. (2019). Telemedicine-based health coaching is effective for inducing weight loss and improving metabolic markers. Telemed J E Health, 25(2), 85-92. doi: 10.1089/tmj.2018.0002.
  22. Befort, C.A., VanWormer, J.J., Desouza, C., Ellerbeck, E.F., Gajewski, B., Kimminau, K.S., et al. (2021). Effect of behavioral therapy with in-clinic or telephone group visits vs in-clinic individual visits on weight loss among patients with obesity in rural clinical practice: A Randomized Clinical Trial. JAMA, 325(4), 363-372. DOI: 10.1001/jama.2020.25855
  23. Jeong, J., Jeon, J., Bae, K., Choi, Y., Park, K., Kim, J., et al. (2018). Smart Care Based on Telemonitoring and Telemedicine for Type 2 Diabetes Care: Multi-Center Randomized Controlled Trial. Telemed J E Health, 24(8), 604-613. doi: 10.1089/tmj.2017.0203
  24. Margolis, K.L., Asche, S.E., Bergdall, A.R., Dehmer, S.P., Groen, S.E., Kadrmas, H.M., et al. (2013). Effect of home blood pressure telemonitoring and pharmacist management on blood pressure control: a cluster randomized clinical trial. JAMA, 310(1), 46-56. DOI:10.1001/jama.2013.6549
  25. Donnelly, J.E., Goetz, J., Gibson, C., Sullivan, D.K., Lee, R., Smith, B.K., et al. (2013). Equivalent weight loss for weight management programs delivered by phone and clinic. Obesity (Silver Spring). 21(10), 1951-9. doi:10.1002/oby.20334.
  26. Hwang, M., Shin, H., Song, M. (2007). Literature review of herbal medicines on treatment of obesity since 2000;mainly about Ephedra Herba. J Korean Med Obes Res, 7(1), 39-54.
  27. Lee, D. (2016). An introduction to propensity score matching methods. Anesth Pain Med, 11, 130-148. DOI: https://doi.org/10.17085/apm.2016.11.2.130
  28. Lee, H., Kim, Y., Park, I. (2013). Calculation of sample size in clinical trials. Clinics Shoulder Elbow, 16(1), 53-57. https://doi.org/10.5397/CiSE.2013.16.1.53
  29. A handbook on clinical trial design and number of subjects. Department of Applied Statistics in National Institute of Toxicological Research. 2008 Oct[cited 2021. Dec 27];p.35. Available from: URL:https://www.mfds.go.kr/brd/m_218/view.do?eq=8573&srchFr=&srchTo=&srchWord=srchTp&srchTp=&itm_seq_1=0&itm_seq_2=0&multi_itm_seq=0&company_cd=&company_nm=&page=64
  30. Pellegrini, D., Torlasco, C., Ochoa, J.E., Parati, G. (2020). Contribution of telemedicine and information technology to hypertension control. Hypertens Res, 43(7), 621-628. DOI: 10.1038/s41440-020-0422-4