• 대한생식의학회:학술대회논문집
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• 1999.11a
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• pp.91-92
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• 1999

• 대한생식의학회:학술대회논문집
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• 1999.11a
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• pp.53.1-53.1
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• 1999

• Clinical and Experimental Reproductive Medicine
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• v.37 no.4
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• pp.321-327
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• 2010

Objective: To evaluate the significance and efficacy of trans-cervical fallopian tube catheterization (TFTC) in diagnosis and optimal treatment modality for tubal blockage. Methods: The retrospective study was performed in those underwent TFTC from January 2005 to December 2009. A total of 342 fallopian tubes in 215 patients which showed tubal blockage in hysterosalpingography (HSG), were subjected to TFTC. Recanalization rate (RR) was compared according to portion of tubal blockage; proximal, isthmic and distal portion and blockage type; tapering, concave, and convex type. Results: In total, RR was 72.5% (248/342 tube). According to the portion of tubal blockage, RR was 83.8% in proximal, 45.6% in isthmic and 100% in distal portion. RR was 92.3% in tapering, 80.2% in concave and 25.5% in convex type, respectively. There were 98 pregnancies in 156 patients after successful recanalization, which shows 62.7% pregnancy rate. Conclusio: TFTC were capable of recanalizing tubal blockage in 248 of 342 tubes in 156 of 215 patients (72.5%). The RR was increased with proximal portion and tapering type tubal blockage.

• Korean Journal of Animal Reproduction
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• v.19 no.4
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• pp.271-281
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• 1996

1960년대에 본격적인 연구가 시도된 난세포질내 정자직접주입법(Intracytoplasmic Sperm Injection ; ICSI)은 1976년에는 Uehara 등에 의한 hamster의 연구에서 최초로 전핵의 형성에까지 성공하였다. 이후 계속된 연구를 통하여 여러 동물종에서 이 방법에 의한 난자의 수정 및 배발달에 성공하여, 1988년에 토끼, 1991년에 소, 1995년에는 생쥐에서 산자의 생산에 성공하였다. 한편, 사람에 있어서는 1988년 Lanzendorf 등에 의해 최초로 사람난자가 난세포질내 정자직접주입법에 의해 수정에 성공한 것이 보고되었으며, 1992년에는 Palermo 등에 의해 이 방법에 의해 수정된 수정란 이식을 통한 임신 및 성공적인 분만이 보고되었다. 난세포질내 정자직접주입법에 있어서는 정자의 운동성 및 첨체반응 등의 유무가 수정에 관여하는 중요한 요인이 아닌 것으로 알려지고 있으며, 성숙한 정자가 아닌 정소상체(미부-두부)정자 혹은 정소내의 미성숙정자를 사용하여 난세포질내 정자직접주입법을 시행하여도 수정 및 임신이 가능한 것으로 보고되었다. 또한 정자세포(spematid)나 원형정자세포(round spermatid)를 수정과 배발달이 관찰되었으며 사람에 있어서는 분만까지 성공하였다. 현재까지 이 난세포질내 정자직접주입법은 학술적으로는 난자-정자가 결합하는 기전을 밝히는 연구에 이용되어 왔으며, 임상적으로는 시험관아기시술에 있어서 정자의 기능, 수 등이 문제가 되어 수정이 어려운 남성불임환자에게 적용하여 좋은 성과를 거두어 왔다. 향후 이 기술은 유전자진단이나 남성불임환자의 처치에 폭넓게 사용될 것으로 기대된다.

• The Journal of Korean Medicine
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• v.27 no.2 s.66
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• pp.44-56
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• 2006

Objectives : This study was to analyze the status of patients with infertility in the department of oriental gynecology in an oriental medical hospital and propose infertility treatment in oriental medicine. Methods : This study was presented with 2,153 cases of infertile women who had visited the department of oriental gynecology in one oriental hospital in Seoul from 2002 to 2004. Results : The total number infertile patients has decreased year by year. The age range of patients was getting higher and the age group between 30 and 35 took up about one half of the total patients. The duration of infertility for less than 3 years held about 50-60% of the total patients, and the mean duration of infertility was $39.18{\pm}29.57$ months (2004). The most common occupations of females were professionals or administrative managers. The secondary infertility was increasing and unexplained infertility increased from 38.2% (in 2002) to 54.4% (in 2004). However the duration of treatment was shorter. This shows that the age range of the patients having oriental-medicine treatment is gradually getting higher and the number of the patients having oriental-medicine treatment and compliance is decreasing. Conclusions : More studies about objectification of oriental medicine need to precede any other studies. Then, it is thought to be necessary to rebuild cooperative relationships between oriental & western medicine through systematic research and political supports and to establish firm foundations of oriental medicine.

• Clinical and Experimental Reproductive Medicine
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• v.19 no.2
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• pp.189-192
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• 1992

In vitro fertilization and embryo transfer was performed in a patient with immunologic infertility. This patient delivered at preterm a normal healthy male infant.

• Journal of Physiology & Pathology in Korean Medicine
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• v.28 no.3
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• pp.355-358
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• 2014

It is not yet clear that treatment for infertility with uterine myoma or adenomyosis. And myomectomy has the risk of side effects and reducing pregnancy rate. Therefore myoma or adenomyosis who want to be pregnant is ecessary. In this study, the patient who had uterine myoma and adenomyosis was treated by Oriental medical treatments such as herbal medicine and acupuncture. After treatment, the patient's menstrual condition was improved and became pregnance. This case report shows that the Oriental medical treatment is effective for infertility patients with uterine myoma or adenomyosis.

• Clinical and Experimental Reproductive Medicine
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• v.25 no.3
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• pp.349-353
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• 1998

It has been well known that infertile women experience not only emotional disturbance but also stress. But there is no concern about male infertility patients. So phychiatric symptoms were studied with SCL-90 (Symptom Check List-90) in 30 infertile men who was operated testicular sperm extraction (TESE) in Samsung Cheil Hospital and in age matched 31 fertile men from Jan. 1998 to Aug. 1998. In 5 symptom dimensions (Obcessive-Compulsive, Interpersonal Sensitivity, Depression, Phobic anxiety, Psychoticisim) scores. The Infertile group scored significantly higher than the control group. The result revealed that infertile men also experienced substantially more psychiatric symptoms than fertile men. Considering this results, psychiatric evaluation and tender care by infertility specialist are necessary for infertile men during and after evaluation and treatment.

• Journal of Korean Medicine for Obesity Research
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• v.5 no.1
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• pp.157-163
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• 2005

Obesity may induce an amenorrhea and ovulation disorder resulted from endocrine dysfunction, and so it is closely linked to infertility. Recently I've experienced a case that a woman complained of infertility with ovulation disorder, polycystic ovary and obesity has succeeded in pregnancy and delivery by the treatment of weight reduction during 2 months.

• Proceedings of the Korean Information Science Society Conference
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• 2004.04b
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• pp.595-597
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• 2004

본 연구에서는 베이지안망을 기초로 불임환자의 임상 데이터에 대한 다양한 실험을 전개한다. 실험을 통해 임신여부에 영향을 주는 요인들간의 상호 의존성을 분석하고. 또 제약조건이 다른 다양한 베이지안망의 대표적 유형으로 나이브 베이지안망(NBN), 베이지안망으로 확장한 나이브 베이지안망(BAN), 일반 베이지안앙(GBN) 분류기들의 분류성능을 서로 비교 분석한다. 베이지안망을 적응할 때 변수의 수가 많아짐에 따라 베이지안망의 구조를 학습하는데 탐색공간이 넓어져 시간의 요구량이 급격히 많아진다. 따라서 이런 탐색공간을 효율적으로 줄이기 위하여 클래스 노드의 Markov blanket에 속한 특징들로 집합을 축소하는 것을 제안하고, 실험을 통해 이 특징 축소 방법이 베이지안망 분류기들의 성능을 높여 줄 수 있는지 알아본다.