Efficacy of Transcervical Fallopian Tube Catheterization in Infertility Patients with Fallopian Tube Occlusion

난관 폐쇄에 기인한 불임 환자에서 난관 개통술의 효용성

  • Park, Chan-Woo (Department of Obstetrics & Gynecology, Cheil General Hospital and Women's Healthcare Center, Kwandong University School of Medicine) ;
  • Cha, Sun-Hwa (Department of Obstetrics & Gynecology, Cheil General Hospital and Women's Healthcare Center, Kwandong University School of Medicine) ;
  • Yang, Kwang-Moon (Department of Obstetrics & Gynecology, Cheil General Hospital and Women's Healthcare Center, Kwandong University School of Medicine) ;
  • Han, Ae-Ra (Department of Obstetrics & Gynecology, Cheil General Hospital and Women's Healthcare Center, Kwandong University School of Medicine) ;
  • Yoo, Ji-Hee (Department of Obstetrics & Gynecology, Cheil General Hospital and Women's Healthcare Center, Kwandong University School of Medicine) ;
  • Song, In-Ok (Department of Obstetrics & Gynecology, Cheil General Hospital and Women's Healthcare Center, Kwandong University School of Medicine) ;
  • Kim, Hye-OK (Department of Obstetrics & Gynecology, Cheil General Hospital and Women's Healthcare Center, Kwandong University School of Medicine) ;
  • Kang, Inn-Soo (Department of Obstetrics & Gynecology, Cheil General Hospital and Women's Healthcare Center, Kwandong University School of Medicine) ;
  • Koong, Mi-Kyoung (Department of Obstetrics & Gynecology, Cheil General Hospital and Women's Healthcare Center, Kwandong University School of Medicine) ;
  • Lee, Kyung-Sang (Department of Radiology, Cheil General Hospital and Women's Healthcare Center, Kwandong University School of Medicine)
  • 박찬우 (관동대학교 의과대학 제일병원 산부인과) ;
  • 차선화 (관동대학교 의과대학 제일병원 산부인과) ;
  • 양광문 (관동대학교 의과대학 제일병원 산부인과) ;
  • 한애라 (관동대학교 의과대학 제일병원 산부인과) ;
  • 유지희 (관동대학교 의과대학 제일병원 산부인과) ;
  • 송인옥 (관동대학교 의과대학 제일병원 산부인과) ;
  • 김혜옥 (관동대학교 의과대학 제일병원 산부인과) ;
  • 강인수 (관동대학교 의과대학 제일병원 산부인과) ;
  • 궁미경 (관동대학교 의과대학 제일병원 산부인과) ;
  • 이경상 (관동대학교 의과대학 제일병원 영상의학과)
  • Received : 2010.11.11
  • Accepted : 2010.12.17
  • Published : 2010.12.31

Abstract

Objective: To evaluate the significance and efficacy of trans-cervical fallopian tube catheterization (TFTC) in diagnosis and optimal treatment modality for tubal blockage. Methods: The retrospective study was performed in those underwent TFTC from January 2005 to December 2009. A total of 342 fallopian tubes in 215 patients which showed tubal blockage in hysterosalpingography (HSG), were subjected to TFTC. Recanalization rate (RR) was compared according to portion of tubal blockage; proximal, isthmic and distal portion and blockage type; tapering, concave, and convex type. Results: In total, RR was 72.5% (248/342 tube). According to the portion of tubal blockage, RR was 83.8% in proximal, 45.6% in isthmic and 100% in distal portion. RR was 92.3% in tapering, 80.2% in concave and 25.5% in convex type, respectively. There were 98 pregnancies in 156 patients after successful recanalization, which shows 62.7% pregnancy rate. Conclusio: TFTC were capable of recanalizing tubal blockage in 248 of 342 tubes in 156 of 215 patients (72.5%). The RR was increased with proximal portion and tapering type tubal blockage.

목적: 불임을 주소로 내원한 환자들을 대상으로 자궁 난관 조영술을 이용한 난관 불임 선별검사에서 난관 막힘의 소견을 보인 경우 선택적 난관 조영술을 시행 후 실패 시 난관 개통술을 시행하여 난관 불임치료에 있어 난관 개통술의 효용성을 알아보고 난관 막힘 부위 및 형태에 따른 난관 개통률을 비교하고자 하였다. 연구방법: 난관 불임 선별검사로서 자궁 난관 조영술을 시행하였으며 자궁 난관 조영술 상 난관 막힘 소견을 보인 215명의 342개의 난관을 대상으로 후향적 연구를 진행하였다. 결과: 난관 개통술을 시행하여 342개의 난관 가운데 248개의 난관이 개통되어 72.5%의 난관 개통률을 보였다. 막힘 부위에 따른 난관 개통률은 근위부 83.8% (197/235예), 협부 45.6% (47/103예), 원위부 100% (4/4예)를 보여 자궁-난관 접합부에 가까운 막힘 일수록 높은 개통률을 보였다. 막힘 형태에 따른 개통률은 점진형은 92.3% (157/170예), 오목형은 80.2% (69/86예), 볼록형은 25.5% (22/86예)의 난관 개통률을 보였다. 난관 막힘 부위와 형태를 종합하여 볼때 난관 근위부 점진형 막힘의 경우 91.6% (143/156예)의 높은 개통률을 보인 반면 난관 협부 볼록형 막힘의 경우에는 개통률이 11.3% (6/53예)에 불과하였다. 난관 개통에 성공한 156명 가운데 98명에서 임신에 성공하여 62.7%의 임신율을 보였다. 결론: 난관 개통술은 자궁 경부를 통한 시술로 수술적 방법이나 체외수정시술의 난자 채취에 비해 덜 침습적인 방법으로 입원치료가 필요하지 않으며 비교적 적은 비용으로 불임의 원인을 극복할 수 있는 장점이 있어 난관 원인에 의한 불임 환자에서 우선적으로 시행해 볼 수 있는 효과적인 치료 방법이라 할 수 있다.

Keywords

References

  1. Musich JR, Behrman SJ. Surgical management of tubal obstruction at the uterotubal junction. Fertil Steril 1983; 40: 423-41. https://doi.org/10.1016/S0015-0282(16)47349-8
  2. Serafini P, Batzofin J. Diagnosis of female infertility. A comprehensive approach. J Reprod Med 1989; 34: 29-40.
  3. Novy MJ, Thurmond AS, Patton P, Uchida BT, Rosch J. Diagnosis of cornual obstruction by transcervical fallopian tube cannulation. Fertil Steril 1988; 50: 434-40. https://doi.org/10.1016/S0015-0282(16)60128-0
  4. Sulak PJ, Letterie GS, Coddington CC, Hayslip CC, Woodward JE, Klein TA. Histology of proximal tubal occlusion. Fertil Steril 1987; 48: 437-40. https://doi.org/10.1016/S0015-0282(16)59413-8
  5. Rubin IC. Uterotubal insufflation; value in the treatment of tubal obstruction to ovular migration. Fertil Steril 1954; 5: 311-24. https://doi.org/10.1016/S0015-0282(16)31680-6
  6. DeCherney AH. Anything you can do I can do better ... or differently! Fertil Steril 1987; 48: 374-6. https://doi.org/10.1016/S0015-0282(16)59401-1
  7. Confino E, Friberg J, Gleicher N. Transcervical balloon tuboplasty. Fertil Steril 1986; 46: 963-6. https://doi.org/10.1016/S0015-0282(16)49844-4
  8. Confino E, Friberg J, Gleicher N. Preliminary experience with transcervical balloon tuboplasty. Am J Obstet Gynecol 1988; 159: 370-5. https://doi.org/10.1016/S0002-9378(88)80087-5
  9. Jansen RP, Anderson JC. Catheterisation of the fallopian tubes from the vagina. Lancet 1987; 2: 309-10.
  10. Platia MP, Krudy AG. Transvaginal fluoroscopic recanalization of a proximally occluded oviduct. Fertil Steril 1985; 44: 704 -6. https://doi.org/10.1016/S0015-0282(16)48992-2
  11. Creasy JL, Clark RL, Cuttino JT, Groff TR. Salpingitis isthmica nodosa: radiologic and clinical correlates. Radiology 1985; 154: 597-600. https://doi.org/10.1148/radiology.154.3.3969459
  12. Johannes LH, Jolande A. Diagnosing the tubal factorslaparoscopy vs. traditional techniques. In: Filicori M, Falmigni C, editors. Treatment of infrtility: the new frontiers. New Jersey: Communications Media for Education; 1998. p.67-74.
  13. DeCherney AH, Kort H, Barney JB, DeVore GR. Increased pregnancy rate with oil-soluble hysterosalpingography dye. Fertil Steril 1980; 33: 407-10. https://doi.org/10.1016/S0015-0282(16)44658-3
  14. Gomel V. Tubal reanastomosis by microsurgery. Fertil Steril 1977; 28: 59-65. https://doi.org/10.1016/S0015-0282(16)42318-6
  15. Roh SI, Kang SO, Kwon HC, Cho JH, Lee SJ, Park JM, et al. Transcervical fallopian tube catheterization for proximal tubal obstruction. Korean J Obstet Gynecol 1992; 35: 1045-53.
  16. Kumpe DA, Zwerdlinger SC, Rothbarth LJ, Durham JD, Albrecht BH. Proximal fallopian tube occlusion: diagnosis and treatment with transcervical fallopian tube catheterization.Radiology 1990; 177: 183-7. https://doi.org/10.1148/radiology.177.1.2144651
  17. LaBerge JM, Ponec DJ, Gordon RL. Fallopian tube catheterization: modified fluoroscopic technique. Radiology 1990; 176: 283-4. https://doi.org/10.1148/radiology.176.1.2353103