• Journal of Convergence for Information Technology
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• v.12 no.1
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• pp.135-143
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• 2022

In this study, the antioxidant and anti-inflammatory properties of Colpomenia sinuosa extracts were identified. Antioxidant experiments included DPPH, ABTS, nitrite scavenging experiments, and FRAP, polyphenol concentration measurements, flavonoid concentration measurements. DPPH assay results showed an antioxidant function of 2.821 mg ascorbic acid/g extract. ABTS assay results showed an antioxidant function of 3.923 mg ascorbic acid/g extract. nitrite assay results showed an antioxidant function of 17.89 mg ascorbic acid/g extract. In FRAP, 1 mg of the Colpomenia sinuosa extract showed a reduction of 2.062±0.177 ㎍ of ascorbic acid. For polyphenols, 62.85±3.18 mg/g was shown. Flavonoids showed 10.01±0.24 mg/g. In the meantime, cell experiments showed cytotoxicity and anti-inflammatory functions. In cytotoxicity experiments, Colpomenia sinuosa extracts showed cytotoxicity of less than 20% and an inflammatory inhibition of 30.93±2.93% at a concentration of 100 ㎍/mL. These results indicate that Colpomenia sinuosa extract is available as functional cosmetic material.

• Journal of the Korean Society of Food Science and Nutrition
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• v.45 no.4
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• pp.492-500
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• 2016

In this study, the effects of Colpomenia sinuosa (CS) extract on serum lipid level and bone formation in an ovariectomized animal model were investigated. Twenty four nine-week old female Sprague-Dawley rats were randomly assigned to four groups: sham-operated rats (SHAM), ovariectomized control rats (OVX-CON), and ovariectomized rats supplemented with CS extract at 50 mg/kg bw (OVX-CS50) or 200 mg/kg bw (OVX-CS200). Three OVX groups were surgically ovariectomized while the SHAM group was sham-operated. CS extract was orally administrated at 1 mL per day. Analysis of serum lipid contents found that the total cholesterol, triglyceride, and low density lipoprotein cholesterol levels in the OVX-CON group were higher than those in the SHAM group. Notably, upon administration of CS extract after ovariectomy, triglyceride levels tended to significantly decrease. In addition, platelet aggregation ability decreased in groups treated with CS extract compared to the OVX-CON group. Serum alkaline phosphatase activity as an indicator of bone formation was lower in the CS extract group compared to the OVX-CON group. Collagen contents in bone and cartilage were reduced by ovariectomy, whereas the CS extract-supplemented groups exhibited higher concentrations in bone. According to these results, CS extract improved serum lipid parameters and osteogenesis in ovariectomized rats.

• 한국신재생에너지학회:학술대회논문집
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• 2006.11a
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• pp.253-256
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• 2006

BEMT나 wake method와 같이 2-D 에어포일의 데이터를 성능과 하중 해석에 이용하는 기법의 경우 에어포일 데이터의 정확도는 전체 결과에 큰 영향을 미친다. 풍력 블레이드와 같은 회정익에서는 2-D 에어포일 데이터를 실험 등을 통하여 정확히 얻어서 적용 시키더라도 예측 결과는 실제값과 큰 차이를 보이는 경우가 많다. 이는 회전익의 유동 특성에 의해 발생하는 실속 지연의 효과로 인한 것이며 이것은 입력에 사용되는 에어포일 데이터에는 반영되지 않으므로 자체적인 보정이 필요하다. 본 연구에서는 이러한 문제를 해결하기 위해 현재 제시되어 있는 실속 지연 모델을 살펴보고 이를 불레이드의 성능과 하중 해석에 저용시켜 보아 그 유효성에 대하여 살펴보았다.

• Journal of Marine Life Science
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• v.4 no.2
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• pp.81-85
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• 2019

This study was carried out to observe the changes of seaweed community in artificial reefs installed in September, 2016 in Namae-ri, Yangyang-gun, and Seokbyeong-ri, Pohangsi, Korea. Field surveys were conducted by SCUBA diving once a season in February, May, August, and November of 2017, and quantitative survey and qualitative survey were carried out in parallel. In this study, a total of 94 species, including 11 green algae, 15 brown algae and 68 red algae were appeared. 66 species (8 green algae, 9 brown algae, 49 red algae) and 65 species (7 green algae, 9 brown algae, 49 red algae) were collected and identified in Yangyang and Pohang. In dominant species, Yangyang was dominant species of Saccharina japonica and subdominant species of Ulva australis. Pohang dominated in order of Colpomenia sinuosa and Gelidium elegans. In both coastal areas, Ulva spp., Colpomenia sinuosa were grown at the early stage of reforestation, and perennial seaweeds such as Saccharina japonica, Ecklonia cava and Gelidium elegans were grown. In order to clarify the clustering relation through flora change, it is necessary to monitor the transition process until the seaweed community is stabilized by observing the long-term change through continuous monitoring.

• Journal of Plant Biology
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• v.35 no.2
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• pp.125-134
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• 1992

Taxonomic account is given to the five species of Scytosiphonaceae, Colpomenia peregrina (Sauvageau) Hamel, Endarachne binghamiae J. Agardh, Hydroclathrus clathratus (C. Agardh) Howe, Petalonia fascia (O. F. Muller) Kuntze, and Scytosiphon lomentaria (Lyngbye) Link, collected from Ullungdo Island, Korea. C. peregrina, introduced for the first time in Korea, is similar to C. sinuosa (Roth) Derbes et SolieI in outer appearance but is distinguished by absence of cuticle over the plurilocular sporangial sori. E. binghamiae accords well with American plants but varies in height and width of the thallus according to seasons. H. clathratus has small cortical cells and large clear medullary cells. P fascia is characterized by one to two celled small cortical layer and two to four celled large medullary layer. S. lomentaria shows variation in gross morphology, especially in height and width of thallus according to seasons.easons.

• Journal of Marine Bioscience and Biotechnology
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• v.13 no.2
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• pp.94-103
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• 2021

Here, we evaluated the anti-glycation effects and renal protective properties of 70% (v/v) ethanolic extract of Colpomenia sinuosa (CSE) against AGEs -induced oxidative stress and apoptosis at different concentrations (1, 5, and 20 ㎍/mL). At 20 ㎍/mL, CSE showed that anti-glycation activities via the inhibition of AGE formation (51.1%), inhibition of AGEs-protein cross-linking (61.7%), and breaking of AGEs-protein cross-links (33.3%), were significantly (###p < 0.001 vs. non-treated group) lower than the nontreated group. Methylglyoxal (MGO) significantly (***p < 0.001) reduced cell viability (24.4%) and increased reactive oxygen species (ROS) level (642.3%), MGO accumulation (119.4 ㎍/mL), and apoptosis (55.0%) in mesangial cells compared to the nontreated group. Pretreatment with CSE significantly (###p < 0.001) increased cell viability (57.8%) and decreased intracellular ROS (96.5%), MGO accumulation (80.0 ㎍/mL), and apoptosis (22.6%) at 20 ㎍/mL. Additionally, we confirmed intracellular AGEs reduction by CSE pretreatment. Consequently, our results suggest that CSE is a good source of natural therapeutics for managing diabetic complications by the antiglycation effect and renal protective activity against MGO-induced oxidative stress.

• Korean Journal of Environment and Ecology
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• v.28 no.1
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• pp.10-23
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• 2014

This study was carried out to examine seaweed community structure and distribution of crustose coralline algae at the intertidal and subtidal zones of Gallam, Samchuk, eastern coast of Korea. Total 112 species including 14 of green algae, 33 of brown algae, and 65 of red algae were collected and identified. Among these species, 29 species were found throughout the year. The dominant species which contributed significantly to the total biomass were Ulva pertusa, Colpomenia spp., Sargassum fulvellum, Sargassum fusiforme, Sargassum muticum, Sargassum thunbergii, Corallina pilulifera, and Gelidium elegans. Annual seaweed biomass in dry weight was 66.7 $gm^{-2}$ and maximum biomass was recorded seasonally in summer (107.5 $gm^{-2}$), while minimum was recorded in autumn (36.2 $gm^{-2}$). In seaweed functional group analyses, coarsely branched form was the most dominant functional group constituting from 40.0 to 48.6% of the total flora. Ecological state group ESG II, as an opportunistic species, including sheet form, filamentous form, and coarsely branched form, consisted of 46~61 species, constituting 76.7~82.4%. Crustose coralline algae was observed throughout all seasons. Species of the crustose coralline algae were largely classified into Lithothamnion lemoineae, Lithophyllum okamurai, Lithophyllum yessoense, and Hydrolithon gardineri. The coverage of crustose coralline algae seems to be lower than that of other studies from 36.8% to 11% on average.

• Journal of the Korean Society of Food Science and Nutrition
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• v.43 no.2
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• pp.224-230
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• 2014

Marine algae have long been recognized as a health and beauty food, based on its anti-tumor, anti-inflammatory and anti-obesity activities. In this study, methanol extracts were prepared from 10 different phaeophyta, after which DPPH radical scavenging and cytoprotective activities of HT-22 cells against ${\beta}$-amyloid protein ($A{\beta}$), which has neurotoxic effects, were investigated. In DPPH experiments, Ecklonia cava and Ishige okamurai showed strong ROS scavenging activities, whereas eight other phaeophyta including Petalonia binghamiae (P. bin) showed weak ROS scavenging activities. To validate the cytoprotective effects of 10 different phaeophyta in $A{\beta}$-induced HT-22 cells, protein expression levels of APP, BACE1, iNOS, phosphorylated ERK1/2, phosphorylated p38 and phosphorylated JNK1/2 were determined along with MTT assay. In the MTT assay, P. bin showed the best effective cytoprotective activity at a concentrations of $25{\mu}g/mL$, whereas Sargassum confusum, Colpomenia sinuosa, Myelophycus simplex, and Sargassum hemiphyllum showed potential. Determination of protein expression levels related to $A{\beta}$-induced neurotoxicity in the five selected phaeophyta showed that P. bin inhibited BACE1 and iNOS expression in $A{\beta}$-induced HT-22 cells. These results indicate that the cytoprotective effects of P. bin are mediated by suppressing the pathways involving $A{\beta}$-induced ERK and p38 activation.