• Title/Summary/Keyword: 분자인식

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Instructional Effect of Cooperative Learning in Problem Solving Strategy (문제 해결 전략에서 협동학습의 효과)

  • Noh, Tae-Hee;Yeo, Kyeong-Hee;Jeon, Kyung-Moon
    • Journal of The Korean Association For Science Education
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    • v.19 no.4
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    • pp.635-644
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    • 1999
  • The effect of cooperative learning in a heuristic approach (four stage-problem solving strategy) that also emphasized molecular level representation was studied. Three high school classes (N=130) were randomly assigned to St group (using strategy individually), St-Co group (using strategy in cooperative group), and control group. After instruction, students' multiple-choice problem solving ability, strategy performing ability, and the perception of involvement were compared. Students' preferred instruction type was also examined. Although multiple-choice problem solving ability were not different significantly, a significant interaction between the treatment and the previous achievement level was found in strategy performing ability. Analysis of simple effects indicated that the medium-level students in the St group performed better than those in the St-Co group. In the perception questionnaire of involvement. however, the scores of the St group were significantly lower than those of the control group. The instruction type that students most preferred was also St-Co.

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Integration of immunohistochemical reactions into Electrochemical and Optical Analyses of Biochips (면역 조직화학 반응이 통합된 바이오칩의 전기화학 및 광학적 분석)

  • Choi Hyoung Gil;Hong Eun Kyoung;Lee Seung-Won;Yoon Hyun C.
    • KSBB Journal
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    • v.20 no.2 s.91
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    • pp.123-128
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    • 2005
  • We have addressed two important issues of immunosensing biochips, including the construction of antibody functionalized suface for efficient affinity reactions and the development of a signal registration strategy that converts biospecific reactions into highly quantifiable electrochemical and/or optical signals. The developed immunoassay reaction is an integrated version of enzyme-mediated immunoprecipitaion reaction, which is widely used in immunohistochemistry, and electrochemical signaling reaction. For the evaluation of analytical performance of fabricated immunosensing biochips, signaling for mouse IgG in antiserum was conducted. Applications of the developed strategy have been found for the evaluation of histology chemicals and for the signal amplification for array-type biochip analysis.

The Influences of Group Composition in Cooperative CAI (협동적 CAI에서 소집단 구성 방법의 효과)

  • Noh, Tae-Hee;Cha, Jeong-Ho;Park, Hye-Young;Kim, Kyoung-Eun
    • Journal of The Korean Association For Science Education
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    • v.22 no.3
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    • pp.508-516
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    • 2002
  • This study investigated the influences of group composition in cooperative computer-assisted instruction (CAI) upon students' conceptual understandings, application abilities, learning motivations, and the perceptions of involvement. Seventh graders (N=97) were selected from a co-ed middle school in Seoul, and taught about 'motion of molecules' for 5 class hours. In the two treatment groups with cooperative CAI strategy, homogeneous and heterogeneous small groups were organized by the previous science achievement. Traditional instructions were administered to the comparison group. Two-way ANCOVA results revealed that the scores of the conception test for the treatment groups were significantly higher than those for the comparison group. However, there was no difference between the homogeneous and the heterogeneous groups. The scores of the three groups did not differ significantly in the application test and the learning motivation test. However, the perceptions of involvement for the treatment groups were more positive than those for the comparison group.

The Effects of Individualized Learning Adapted to Students' Conceptions Using Smart Devices in Science Instruction (과학 수업에서 스마트 기기를 활용한 개념 적응적 개별화 학습의 효과)

  • Yun, Jeonghyun;Ahn, Inyoung;Noh, Taehee
    • Journal of The Korean Association For Science Education
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    • v.35 no.2
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    • pp.325-331
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    • 2015
  • In this study, we investigated the effects of individualized learning adapted to students' conceptions using smart devices in science instruction upon students' conceptual understanding, the retention of conception, achievement, learning motivation, enjoyment of science lessons, and perception about individualized learning using smart devices. Four seventh-grade classes at a coed middle school in Seoul were assigned to a control group and a treatment group. Students were taught about molecular motions for seven class periods. Two-way ANCOVA results revealed that the scores of a conception test, the retention of the conception test, a learning motivation test, and an enjoyment of science lessons test for the treatment group were significantly higher than those for the control group. Although the score of the treatment group was higher than that of the control group in the achievement test, the difference was not statistically significant. Students' perceptions about individualized learning using smart devices were also found to be positive.

The Effect of an Instruction Using Generating Analogy on Students’ Conceptual Understanding in Middle School Science Concept Learning (중학교 과학 개념 학습에서 비유 만들기를 이용한 수업이 학생들의 개념 이해에 미치는 효과)

  • No, Tae-Hui;Kim, Gyeong-Sun;Choe, Eun-Gyu;Cha, Jeong-Ho
    • Journal of the Korean Chemical Society
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    • v.50 no.4
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    • pp.338-345
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    • 2006
  • study investigated the effect of an instruction using generating analogy on scientific conceptual understanding, science learning motivation, attitude toward science instruction, and perception of instruction. Two classes of seventh graders at a middle school in Seoul were randomly assigned to the treatment group and the control group, and they were taught about the motion of molecules for 5 class hours. The instruction for treatment group was developed based on the Glynns Teaching-With-Analogy model. Two-way ANCOVA results revealed that the scores of the treatment group were significantly higher than those of the control group in the conception test. However, there was no significant difference between two groups in the science learning motivation test and the test on the attitude toward science instruction. Survey results on the students perception of instruction showed that generating analogy was hard for the greater part of students, and finding appropriate analog was the most difficult work. Educational implications are discussed.

The effects of CAI adapting to the level of students' conceptual understanding in concept learning (개념 학습에서 학생들의 개념 이해 수준에 적응적인 CAI의 효과)

  • Kim, Kyung-sun;Kang, Yi-young;Kwon, Hyeok-soon;Wang, Hye-nam;Noh, Tae-hee
    • The Journal of Korean Association of Computer Education
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    • v.9 no.2
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    • pp.79-88
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    • 2006
  • This study investigated the effects of computer-assisted instruction adapting to the level of students' conceptual understanding upon students' conceptual understanding, retention of conceptions, learning motivation, and perception about computer-assisted instruction in concept learning. 94 seventh grade students from a coed middle school in Seoul were randomly assigned to control, CAI, adaptive CAI groups, and were taught about 'motion of molecules' for 7 class periods. Two-way ANCOVA results revealed that the scores of a conception test and a learning motivation test for the adaptive CAI group were significantly higher than those for the control group. The scores of a retention test of conceptions for the adaptive CAI group were significantly higher than those for other two groups. There were no significant interactions between the instruction and the level of previous achievement in the scores of the conception test, the learning motivation test, and the retention test of conceptions. The perception about computer-assisted instruction for the students of the adaptive CAI group were more positive than those for the students of the CAI group.

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Characterization of Mushroom Tyrosinase Inhibitor in Sweet Potato (고구마에 존재하는 mushroom tyrosinase 저해제의 특성)

  • Lee Hyun-Ju;Lee Min-Kyung;Park In-Shik
    • Journal of Life Science
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    • v.16 no.3 s.76
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    • pp.396-399
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    • 2006
  • Crude extract prepared from sweet potato possessed inhibitory activity toward mushroom tyrosinase. The inhibitory activity was dependent upon the addition amount of sweet potato extract. After heating the sweet potato extract at $95^{\circ}C$ for 20 min, its inhibitory activity retained 37.3%. Its optimum activity was shown at pH ranges of 5.0-7.0. The tyrosinase inhibitory activity was disappeared by dialysis, which suggests the inhibitory activity of sweet potato extract is caused by some compounds of low molecular weight.

Synthesis of Molecularly Imprinted Polymers for Chiral (S)-Ibuprofen and Their Molecular Recognition Mechanism (키랄(S)-이부푸로펜 함유 고분자의 합성과 제조된 고분자의 분자 인식 메카니즘)

  • Huangfu, Fengyun;Wang, Bing;Sun, Yan
    • Polymer(Korea)
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    • v.37 no.3
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    • pp.288-293
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    • 2013
  • A group of molecularly imprinted polymers (MIPs) with specific recognition for chiral (S)-ibuprofen were successfully prepared based on hydrogen bonds, utilizing ${\alpha}$-methacrylic acid as a functional monomer. The IR analysis of MIPs showed that the blue- and red-shifted hydrogen bonds were formed between templates and functional monomers in the process of self-assembly imprinting and re-recognition, respectively. According to UV-Vis analysis, we found that the ratio of host-guest complexes between template molecule and functional monomer was 1:1. The effect of cross-linker's quantity on the polymerization was studied by transmission electron microscope (TEM). The adsorption selectivity experiments indicated that MIPs exhibited higher selectivity to (S)-ibuprofen than those to ketoprofen and (R)-ibuprofen, (S)-ibuprofen's structural analogs.

Hybrid Retrieval Machine for Recognizing 3-D Protein Molecules (3차원 단백질 분자 인식을 위한 복합 추출기)

  • Lee, Hang-Chan
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.59 no.5
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    • pp.990-995
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    • 2010
  • Harris corner detector is commonly used to detect feature points for recognizing 2-D or 3-D objects. However, the feature points calculated from both of query and target objects need to be same positions to guarantee accurate recognitions. In order to check the positions of calculated feature points, we generate a Huffman tree which is based on adjacent feature values as inputs. However, the structures of two Huffman trees will be same as long as both of a query and targets have same feature values no matter how different their positions are. In this paper, we sort feature values and calculate the Euclidean distances of coordinates between two adjacent feature values. The Huffman Tree is generated with these Euclidean distances. As a result, the information of point locations can be included in the generated Huffman tree. This is the main strategy for accurate recognitions. We call this system as the HRM(Hybrid Retrieval Machine). This system works very well even when artificial random noises are added to original data. HRM can be used to recognize biological data such as proteins, and it will curtail the costs which are required to biological experiments.

Taxonomic recognition of Saussurea maximowiczii var. triceps on Jejudo Island (한라분취의 분류학적 인식)

  • KIM, Byeol-Ah;SUN, Eun-Mi;YUN, Seon-Ah;KIM, Seung-Cheol;IM, Hyoung-Tak
    • Korean Journal of Plant Taxonomy
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    • v.48 no.1
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    • pp.24-36
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    • 2018
  • A morphological and molecular survey was conducted to determine the taxonomic status of Saussurea maximowiczii var. triceps on Jejudo Island. Although it tends to be smaller than S. maximowiczii with regard to typical quantitative characters of vegetative organs, including the plant height and leaf size, these two taxa cannot be distinguished from each other based on major reproductive characters, including the involucre and florets. Molecular data support the contention that S. triceps and S. maximowiczii are monophyletic taxa. Saussurea maximowiczii var. triceps is found to be an ecological phenotype of S. maximowiczii that has adapted particularly to the windy highlands of Hallasan Mountain on Jejudo Island.