• Clean Technology
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• v.25 no.4
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• pp.283-288
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• 2019

Monodisperse microparticles has been particularly enabling for various applications in the encapsulation and delivery of pharmaceutical agents. The microfluidic devices are attractive candidates to produce highly uniform droplets that serve as templates to form monodisperse microparticles. The microfluidic devices that have micro-scale channel allow precise control of the balance between surface tension and viscous forces in two-phase flows. One of its essential abilities is to generate highly monodisperse droplets. In this paper, a microfluidic approach for preparing monodisperse polycaprolactone (PCL) microparticles is presented. The microfluidic devices that have a flow-focusing generator are manufactured by soft-lithography using polydimethylsiloxane (PDMS). The crucial factors in the droplet generation are the controllability of size and monodispersity of the microdroplets. For this, the volumetric flow rates of the dispersed phase of oil solution and the continuous phase of water to generate monodisperse droplets are optimized. As a result, the optimal flow condition for droplet dripping region that is able to generate uniform droplet is found. Furthermore, the droplets containing PCL polymer by solvent evaporation after collection of droplet from device is solidified to generate the microparticle. The particle size can be controlled by tuning the flow rate and the size of the microchannel. The monodispersity of the PCL particles is measured by a coefficient of variation (CV) below 5%.

• Journal of the Korean Society for Railway
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• v.20 no.1
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• pp.64-75
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• 2017

The role of a track subgrade is to provide bearing capacity and distribute load transferred to lower foundation soils. Track subgrade soils are usually compacted by heavy mechanical machines in the field, such that sometimes they are attributed to progressive residual settlement during the service after construction completion of the railway track. The progressive residual settlement generated in the upper part of a track subgrade is mostly non-recoverable plastic deformation, which causes unstable conditions such as track irregularity. Nonetheless, up to now no design code for allowable residual settlement of subgrade in a railway trackbed has been proposed based on mechanical testing, such as repetitive triaxial testing. At this time, to check the DOC or stiffness of the soil, field test criteria for compacted track subgrade are composed of data from RPBT and field compaction testing. However, the field test criteria do not provide critical design values obtained from mechanical test results that can offer correct information about allowable permanent deformation. In this study, a test procedure is proposed for permanent deformation of compacted subgrade soil that is used usually in railway trackbed in the laboratory using repetitive triaxial testing. To develop the test procedure, an FEA was performed to obtain the shear stress ratio (${\tau}/{\tau}_f$) and the confining stress (${\sigma}_3$) on the top of the subgrade. Comprehensive repetitive triaxial tests were performed using the proposed test procedure on several field subgrade soils obtained in construction sites of railway trackbeds. A permanent deformation model was proposed using the test results for the railway track.

• The Journal of Korean Academy of Prosthodontics
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• v.53 no.1
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• pp.1-8
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• 2015

Purpose: The purpose of this prospective study was to compare the satisfaction levels of the patients worn implant supported mandibular overdentures and conventional complete dentures. Materials and methods: Full edentulous patients (n=40) who were planned to do implant supported mandibular overdentures, aged 51 to 82 years, were enrolled in this study. All subjects rated their satisfaction levels (mastication, pronunciation, esthetics, pain, and general satisfaction) of their original conventional dentures prior to treatment and their new overdentures 1 week and 12 weeks after the delivery on 10 cm visual analogue scales. Repeated-measures ANOVA was performed to compare the satisfaction level of each three period (P<.05). Results: The mean satisfaction levels of the implant supported overdentures after 1 week and 12 weeks of delivery were significantly higher than those of the conventional complete dentures in all scoring parameters (P<.05). After 12 weeks of overdenture delivery, the increase of the satisfaction levels in mastication, pronunciation, and pain and the decrease in esthetics and general satisfaction were observed in comparison with those after 1 week of delivery, however, no significant difference was found between the satisfaction levels of 1 week and 12 weeks after delivery. Conclusion: An implant supported overdenture might be one of the effective ways to give more satisfaction to patients who were not gratified with a conventional denture and eventually to improve their quality of life.

• KIPS Transactions on Software and Data Engineering
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• v.7 no.8
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• pp.297-306
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• 2018

In this paper, we address how to apply Apache Storm, a distributed stream processing framework, to InfiniBand, a high performance communication device. An easy way to run Storm on InfiniBand is to simply use IPoIP (IP over InfiniBand). However, this method causes a serious CPU load on the node, which is caused by frequent context switches and buffer copies. To solve this problem, we propose a new communication method using InfiniBand's Remote Direct Memory Access (RDMA) function in Storm. First, we design and implement RJ-Netty (RDMA/JXIO Netty), a new framework that replaces Netty, the legacy framework, to exploit RDMA functionality. Second, we reimplement the related classes so that Storm can use both existing Netty and new RJ-Netty. Third, we extend the JXIO server functionality so as to support multi-threading to maximize the performance of RJ-Netty. Experimental results show that the proposed RJ-Netty significantly reduces CPU load while improving message throughput compared to IPoIB as well as Ethernet. This paper is the first attempt to run Apache Storm on InfiniBand, and we believe that it is an excellent research result that improves the performance of Storm by using InfiniBand RDMA.

• Journal of the Korean Chemical Society
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• v.47 no.5
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• pp.479-486
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• 2003

In this study, poly(DL-lactide-co-glycolide) nanoparticles loaded with water-insoluble vitamins such as vitamin A (Retinol) and vitamin E acetate were prepared by the emulsification diffusion method. Polymer solution was prepared by the two water-miscible organic solvent, such as ethanol and acetone. Because of its biocompatible property, polyethyleneglycol-polypropyleneglycol diblock copolymer was used as surfactant and stabilizer. The influence of some preparative variables on the nanoparticle formation and on the loading efficiency of active agents, such as the type and concentration of stabilizing agent, the stirring methods, the water/oil phase ratio and the polymer concentration were investigated in order to control and optimize the process. After preparation of nanoparticles loaded with active agent, particle size and distribution were evaluated by the light scattering particle analyzer. The loading efficiency of active agents was evaluated by the UV-visible spectroscopy. As the results, particle size were 50-200 nm and dispersibility was monodisperse. The optimum loading efficiency of active agents was observed 50-60%. It was found that the appropriate of selections of binary solvent mixtures and polymeric concentrations in both organic and aqueous phases could provide good yield and favorable physical properties of PLGA nanoparticles.

• Korean Journal of Agricultural and Forest Meteorology
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• v.11 no.1
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• pp.27-38
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• 2009

The multi-level profile system is designed to measure the vertical profile of $H_2O$ and $CO_2$ concentrations in the surface layer to estimate the storage effects within the plant canopy. It is suitable for long-term experiments and can be used also in advection studies for estimating the spatial variability and vertical gradients in concentration. It enables the user to calculate vertical fluxes of water vapor, $CO_2$ and other trace gases using the surface layer similarity theory and to infer their sources or sinks. The profile system described in this report includes the following components: sampling system, calibration and flow control system, closed path infrared gas analyzer(IRGA), vacuum pump and a datalogger. The sampling system draws air from 8 inlets into the IRGA in a sequence, so that for 80 seconds air from all levels is measured. The calibration system, controlled by the datalogger, compensates for any deviations in the calibration of the IRGA by using gas sources with known concentrations. The datalogger switches the corresponding valves, measures the linearized voltages from the IRGA, calculates the concentrations for each monitoring level, performs statistical analysis and stores the final data. All critical components are mounted in an environmental enclosure and can operate with little maintenance over long periods of time. This report, as a practical manual, is designed to provide helpful information for those who are interested in using profile system to measure evapotranspiration and net ecosystem exchanges in complex terrain.

• Journal of the Society of Naval Architects of Korea
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• v.32 no.1
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• pp.42-57
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• 1995

An efficient and accurate scheme has been constructed by taking advantages of the hi-quadratic spline scheme and the higher-order boundary element method selectively depending on computation domains. Boundary surfaces are represented by 8-node boundary elements to describe curved surfaces of a ship and its neighboring free surface more accurately. The variation of the velocity potential complies with the characteristics of the 8-node element on the body surface. But on the free surface, it is assumed to follow that of the hi-quadratic spline scheme. By which, the free surface solution is free from numerical damping and has better numerical dispersion property. As numerical examples, steady and unsteady Neumann-Kelvin problems are considered. Numerical results for a submerged spheroid, Series 60($C_B=0.6$) and a modified support the proposed method. Finally, a new upstream radiation condition is derived using a wave equation operator in order to deal with problems for subcritical reduced frequency. The relevance of this operator has been confirmed in the case of unsteady Kelvin source potential.

• The Korean Journal of Applied Statistics
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• v.1 no.2
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• pp.34-44
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• 1987

In order to estimate the optimum fertilizer level for rice, a major food crop, the experimental results obtained from the fertilizer trials conducted at 642 experimental sites(farmers' fields) throughout the country for the period from 1976 to 1979 were examined. Since non-significant interactions among fertilizers have been ovserved from the past experiences, only thirteen treatments(combinations of fertilizer levels) for the experiments as given in the Table 1 were chosen such that simple response curves can be fitted with independent variables being N, $P_2O_5, and K_2O$. Weighted combining analysis of variance was also carried out for each type of paddy fields to test the significance of Treatments $\times$ Experimental sites interaction, and highly significant variability in response to treatments among experimental sites in the same type of paddy fields was observed in most types of fields. For the types of paddy fields where the treatments $\times$ experimental sites interaction was not significant, separate response curves for N, $P_2O_5, and K_2O$ were estimated on the basis of the mean yields of rice, and common values of the optimum levels of fertilizers were extimated thereform. When the interaction is significant, response curves were fitted for each experimental sites. The average fertilizer doses estimated for the types of paddy fields based on the individual sites are given in Tables 7-1 and 7-2.

• Journal of Dental Rehabilitation and Applied Science
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• v.36 no.1
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• pp.1-11
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• 2020

Purpose: The purpose was to compare shear bond strength (SBS) of three types of resin for temporary restoration to polyetherketoneketone (PEKK) depending on surface modification. Materials and Methods: Sixty disks made from PEKK were air-abraded with 110 ㎛ alumina particles (Cobra, Renfert GmbH, Hilzinge, Germany) and thirty specimens were divided into two groups each: PEKK without Visio.link (Bredent, Senden, Germany)(U) and with Visio.link (P). Resins for temporary restoration (polymethylmethacrylate; PMMA, polyethylmethacrylate; PEMA, bis-acryl composite resin) in the shape of a square with one side 3.2 mm were bonded to PEKK twenty respectively and classified into six groups (UM, UE, UC, PM, PE and PC). All specimens were stored in distilled water at 37℃ for 24 hours. SBS of each group was measured at a crosshead speed of 2 mm/min in universal testing machine. SBS was compared using one-way ANOVA and a Tukey HSD test (P = 0.05). Results: Group UM and group UE showed a significant difference in SBS with group UC (P < 0.05). Group PC showed a significant increase in SBS than group UC (P < 0.05). Conclusion: It is recommended to apply Visio.link to PEKK for adhering bis-acrylic composite resin, but not for PMMA and PEMA in clinical practice.

• Journal of Hospice and Palliative Care
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• v.14 no.3
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• pp.144-151
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• 2011

Purpose: This study was conducted to compare nursing students' attitudes toward death, self-esteem and life satisfaction according to clinical experience. Methods: We surveyed 1,030 nursing students from two different universities with a questionnaire consisting of items regarding attitudes toward death, self-esteem and life satisfaction. The data were analyzed using a PASW program. Results: Students with clinical experience scored 2.85 on the attitude toward death, while those without clinical experience scored 2.79 (t=2.775, P=0.006). Students with clinical experience had significantly higher self-esteem (t=4.541, P<0.001) and life satisfaction (t=4.050, P<0.001) than those without it. Students with clinical experience showed correlations between attitude toward death and self-esteem (r=0.159, P<0.001) and life satisfaction (r=0.090, P=0.025), while those without it did not (r=0.106, P=0.014). Conclusion: These results provide guidance for developing educational strategies such as educational program to help students build positive attitude toward death through their experience in clinical practice.