• 한국약용작물학회:학술대회논문집
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• 2012.05a
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• pp.197-198
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• 2012

• Journal of the Korean Society of Industry Convergence
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• v.3 no.4
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• pp.353-360
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• 2000

The purpose of this research is to find the fundamental data for the design and optimum operation condition for the disk atomization comparing the atomization characteristics of the modified straight vane type disk atomizer and the cup type atomizer widely used in the field of spray dry. First, the experimental comparison of the characteristics of $Na_2SO_4$ atomization has been carried out using the cup type disk atomizer and the three kinds of vane type atomization designed specially for the experiment. After the comparison of the experimental data of the $Na_2SO_4$ and raw milk have been conducted using vane type atomizer.

• Journal of Powder Materials
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• v.30 no.1
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• pp.47-52
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• 2023

The purpose of this study is to develop and evaluate amorphous spray-dried microparticles (SDM) containing levosulpiride to increase its solubility. SDM are prepared via solvent evaporation using polyvinylpyrrolidone (PVP) as the water-soluble polymer and Cremophor RH40 as the surfactant. The SDM is prepared by varying the amounts of PVP and Cremophor RH40, and its physicochemical properties, solubility, and dissolution are confirmed. All levosulpiride-loaded SDMs converted the crystalline drug into an amorphous form, significantly improving drug solubility and dissolution compared with the drug alone. SDM consisting of drug/PVP/Cremophor RH40 in a weight ratio of 5:10:3, with increased solubility (720 ± 36 vs. 1822 ± 51 ㎍/mL) and dissolution rate (10.3 ± 2.2 vs. 92.6 ± 6.0%) compared with drug alone, shows potential as a commercial drug for improved oral bioavailability of levosulpiride.

• Food Science of Animal Resources
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• v.29 no.4
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• pp.457-465
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• 2009

The characteristics of Holstein colostrum according to the methods that were employed in processing it were analyzed in this study to improve its industrial utilization. Colostrum samples were collected from the dairy farm of the National Institute of Animal Science (NIAS). The milk fat, protein, lactose, and SNF contents of colostrum were 4.34, 6.99, 3.37, and 11.10%, respectively. The effects of spray drying, freeze drying, freezing, acidification, and inoculation of lactic-acid bacteria on the characteristics of colostrum were then compared. The freezing of colostrum was found to be proper for long-term storage in a farm. Freeze-dried colostrum powder could not meet the processing requirements and the component standards for animal products in terms of the total bacterial and coliform bacteria counts, but spray-dried colostrum powder could meet the microbiological requirements because of its bactericidal effect during the spray-dry treatment. The inoculation of lactic-acid bacteria showed a better inhibitory effect on coliform than the acidification treatment, but protein precipitation appeared because of the low pH and the high acidity. To estimate the effects of the processing methods employed on the IgG of colostrum, the IgG contents of the milk treated by long temperature long time (LTLT) ($65^{\circ}C$, 30 min), by inoculating the lactic acid bacteria starter, by spray drying, and by freeze drying were measured. The IgG contents of the colostrum were changed significantly by the processing treatment employed, from 53.98 mg/mLto 33.28, 34.82, 21.98, and 36.89 mg/mL, respectively.

• Food Science and Preservation
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• v.20 no.5
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• pp.659-667
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• 2013

This study was performed to determine the effects of the blanching condition (immersion ratio 1:15 (w/v) for 3 min at $95^{\circ}C$, and solution containing 1% sodium chloride) and selected forming agents (dextrin DE=10, dextrin DE=20, ${\beta}$-cyclodextrin; each forming agents added 5%) on the phytochemical compounds and quality characteristics of Ligularia fischeri leaves. The moisture was not affected by the forming agent. The color of a, b and chroma values were low in the blanching treatment groups and were significantly lowest with ${\beta}$-cyclodextrin (CD). The polyphenol and flavonoid contents in the blanching treatment groups were higher than those in the non-blanching-treatment group. The ascorbic acid content was higher in the non-blanching-treatment group and was significantly highest in the group treated with dextrin (DE=10) whereas the blanching treatment groups showed lower dehydroascorbic acid content than the non-blanching-treatment group. The water absorption was higher in the non-blanching-treatment group and was significantly highest in the group treated with CD. The water solubility in the blanching treatment groups treated with dextrin (DE=20) and CD was higher than that in the blanching treatment group treated with DE=10. The total chlorophyll and chlorophyll a and b contents were high in the blanching treatment group treated with CD, and for the total carotenoid contents, the same tendency as that seen with the chlorophyll content was observed. With regard to the particle diameter, those in the blanching treatment groups were lower than that in the non-blanching-treatment group and was significantly lowest in the blanching treatment groups treated with DE=20 and CD. The result of SEM observation showed that the spray-dried powders in blanching treatment groups treated with the DE=20 and CD forming agents had uniform particle distribution.

• Journal of Biosystems Engineering
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• v.17 no.3
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• pp.229-236
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• 1992

In an effort to localize the spray-dryer which is markedly used for drying food materials, a experiment was carried out with a wheel type atomizer locally designed and manufactured to evaluate the effect of rotational speed, feed rate and physical properties of liquid food material on the droplet size, and to develop a model to predict the droplet size sprayed at various operational conditions. The result are summarized as follows. 1. The frequency of droplet size sprayed from the atomizer at every treatment were similar to normal distributions. 2. Under the test conditions adopted in this study, that is, rotational speed of the atomizer ranging from 15,000 to 20,000 rpm (55.0 m/sec - 73.3 m/sec), feed rate from 14 to 37 kg/hr and viscosity of the material from 1.14 to 350 cP, the mean volume-surface dia. of droplets was decreased as increase in rotational speed and was not affected significantly by the feed rate and viscosity. 3. Through the dimensional analysis, a prediction model was developed as follows : $$\frac{Dvs}{r}=K[\frac{Q}{{\mu}r}]^a[\frac{rN^2}{g}]^b[\frac{{\rho}^2r^3g}{{\mu}^2}]^c[\frac{L}{r}]^d$$ and it was proved that the above model was better in degree of fitness than other models reported. 4. A prediction equation for the droplet size sprayed from the atomizer under the test was expressed as follows : $$\frac{Dvs}{r}=0.0215[\frac{Q}{{\mu}r}]^{0.06}[\frac{rN^2}{g}]^{0.3314}[\frac{{\mu}^2}{{\rho}^2r^3g}]^{0.0158}$$.

• Applied Chemistry for Engineering
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• v.7 no.6
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• pp.1147-1155
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• 1996

In the spray drying with rotating wheel atomizer of cheese powder, the relationships among variables were analyzed with Response Surface Methodology in which several independent variables such as total solid content, wheel rotation speed, and outlet temperature influenced dependent variables such as particle diameter, moisture content, bulk density, and viscosity of suspended liquid. Significance and correlation were tested according to central composite design. As a results of analyzing the correlations between independent and dependent variables, particle diameter and moisture content of cheese powder were decreased with increasing wheel rotation speed, and bulk density was decreased with increasing outlet temperature. Viscosity of suspended liquid were increased with increasing wheel rotation speed and total moisture content. In correlation among dependent variables, moisture content was proportional to bulk density, and particle diameter was inversly proportional to moisture content and bulk density.

• Journal of Climate Change Research
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• v.2 no.2
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• pp.107-113
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• 2011

In this research, we described the experimental results for the improvement of Potassium based sorbents. These sorbents have been actually used in the 0.5 MW $CO_2$ capture plant located in Hadong #3 Power Plant. Firstly, we had shaped two kinds of sorbents using a spray dryer. These sorbents applied magnetite & copper oxide as an additive. And the magnetite sorbent was evaluated more excellent relatively in the attrition index. Secondly, We had obtained TGA multicycle experimental results of the improved Potassium based sorbent which applied magnetite as an additive. Consequently, $CO_2$ sorption capacity had been sustained 5.5 wt% after 2nd cycle and attrition index was very excellent as 0.5%. Finally, we had investigated the characteristics of the sorbent following in properties of supporters. As a result, the sorption capacity of the KMO sorbent used base material as a supporter was appeared as 7.2 wt%.

• Journal of the Korean Crystal Growth and Crystal Technology
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• v.4 no.2
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• pp.178-189
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• 1994

Fine $BaTiO_3$ powder was synthesized from the various starting solution with 0.05 M by ultrasonic spray pyrolysis method. The conditions of synthesis were fixed on flow rate was 0.5 cm/sec, low temperature furnace was $300^{\circ}C$, and high temperatures furnace was $700^{\circ}C$. The formation procedure was investigated directly by SEM with the collected particle from the each reaction step. Also, the trace of particle in reaction tube was researched theoretically. Fine $BaTiO_3$ was synthesized only in the case of nitrate aqueous solution. The synthesized $BaTiO_3$ powder was porous and spherical which was consist of primary particle at the size of 19.1 nm. The formation procedure was as follows : the particle size decreased in drying step and then increased in initial thermal decomposition step. Finally, particle size was decreased to $0.42 {mu}m$. The trace of particle in reaction tube was also theoretically simulated and discussed.

• Polymer(Korea)
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• v.39 no.1
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• pp.6-12
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• 2015

In order to improve the poor water solubility of aceclofenac, it was loaded into solid Kollidon VA 64 dispersion prepared by spray drying and rotary evaporation methods using different drug and polymer ratios. Morphology and physicochemical behavior of the aceclofenac loaded solid dispersions was analyzed by scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR), X-ray diffractometry (XRD), and differential scanning calorimetry (DSC). Encapsulation efficiency and dissolution behavior in a simulated intestinal juice of aceclofenac in the solid dispersions was measured using HPLC and the latter was compared with that of the active pharmaceutical ingredient (API) and Airtal$^{(R)}$. It was demonstrated that two methods could significantly improve the dissolution behavior of aceclofenac.