• The Journal of Korean Obstetrics and Gynecology
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• v.23 no.2
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• pp.85-94
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• 2010

Purpose: This study aimed to investigate a clinical effect of Coo-Sun activity focusing on improvement of quality of life in female cancer patients. Methods: The subject of study consisted of 5 female cancer patients at the East-West Cancer Center of OO Oriental hospital. The survey methods of this study are Functional Assessment of Cancer Therapy-General (FACT-G) and State-Trait Anxiety Inventory (STAI). Patients performed Coo-Sun activity 6 times a week and filled out FACT-G and STAI questionnaire after every 3 times training. Results: In FACT-G questionnaire, physical well-being and emotional wellbeing was improved significantly after Coo-Sun activity. And change of social/family well-being and functional well-being score were not significant statistically. In STAI questionnaire, STAI1 was improved significantly after Coo-Sun activity. And change of STAI2 score was not significant statistically. Conclusion: After Coo-Sun activity, quality of life (QOL) in female cancer patients was improved and anxiety was decreased. But this study have limitation to prove effects of Coo-Sun activity completely in female cancer patients. So well designed prospective cohort study will be needed to prove its benefits.

• The Journal of Korean Obstetrics and Gynecology
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• v.23 no.1
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• pp.1-11
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• 2010

Purpose: This study was designed to investigate the antimetastatic and immunomodulating effects of extracts of Ulmus davidiana extracts(U. D. Ex.). Methods: Antimetastatic experiments were conducted in vitro and in vivo by using colon 26-M3.1 carcinoma, L5178Y-R lymphoma cell and Hela cell. To observe the immunomodulating effects of U. D. Ex., we measured IL-6, IL-10, IL-12 and TNF-$\alpha$ from peritoneal macrophages. And we evaluated the activation of NK cell by using anti-asialo-GM1 serum. Results: We found that the administration of U. D. Ex. significantly inhibited tumor metastasis in vivo. In vitro cytotoxicity analysis, cell growth are closer to 100% in case of Colon 26-M3.1 carcinoma, L5178Y-R lymphoma cell and Hela cell at low concentration. In case of macrophage, cell proliferation is closer to 100% less than $250{\mu}g/ml$ of U. D. Ex.. The level of cytokine such as IL-6, IL-10, IL-12 which stimulates U. D. Ex. was increased in dose-dependent manner compared to the control group. In case of TNF-$\alpha$, the level was increased at concentration of $1,000{\mu}g/ml$. The depletion of NK cells by anti-asialo GM1 serum partly abolished the inhibitory effect of U. D. Ex. on tumor metastasis. Conclusion: Ulmus davidiana appears to have considerable activity on the anti-metastasis by activation the immune system.

• The Journal of Korean Obstetrics and Gynecology
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• v.23 no.2
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• pp.116-123
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• 2010

Purpose: During Postpartum period many women complain multiple pain, cold hypersensitivity, hot flush, sweating and so on. We call the postpartum disease as San Hu Pung. We studied DITI Characters of women suffering from Postpartum disease. Methods: We studied 74 postpartum women visiting OOhospital from February 2006 to December 2009. The subjects were categorized in two groups, symptom group and no symptom group. We measured the temperatures of abdomen, upper and lower limb and back. We studied the difference of DITI between two groups by Student T-test using SPSS for windows(version 17.0). Results: The general characteristics were not different statistically. Temperatures of abdomen and back of two groups were not different statistically. Temperatures of both LR3 of symptom group were statistically higher than no symptom group. The difference of both PC8 and LU4, both LR3 and ST32 of symptom group were statistically higher than no symptom group. Conclusion: The results suggest that women suffering from Postpartum disease shows high temperatures on hand and foot. It seems that postpartum disease patients tend to have blood deficiency. DITI can be useful to diagnose San Hu Pung. More studies to diagnose San Hu Pung would be needed.

• The Journal of Korean Obstetrics and Gynecology
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• v.23 no.1
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• pp.30-41
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• 2010

Purpose: This study was to observe the effect of "herbal decoction for sitz bath" on dermoepidermal recovery to wound tissue in rat's skin. Methods: The samples were assigned to 3 groups: control group : without any treatment, positive control group : potarose 10% solution, experiment group : herbal decoction for sitz bath. We made the open wound of $2{\times}2cm^2$ size that cut deep into the dermis. Treating the open wound for 17 days, we observed the size of the wound diminishing. On 17th days, the cell viability was measured by MTT assay. The effect anti-inflammatory and dermoepidermal recovery were examined by H&E staining, immunohystochemical staining for MIP-2, FGF. Results: The experiment group showed more recovery from the open wound comparing the control group and the positive control group on 10th days after wounding. But there was not remarkable difference between the experiment and positive control group after 17th days post-wounding. The number of MIP-2 positive reacted cell were significantly decreased and that of FGF positive reacted cell were significantly increased than positive control group at 17th days. Conclusion: According to these results, we finally concluded that "herbal decoction for sitz bath" could be effective in recovery to wound tissue.

• The Journal of Korean Obstetrics and Gynecology
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• v.23 no.1
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• pp.53-64
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• 2010

Purpose: This study was performed to observe the correlation between Hot flush and pulse wave velocity(PWV), ankle brachial index(ABI) in the Climacteric women. Methods: We studied 63 climacteric women visiting OO hospital from 8th January 2007 to 22nd April 2009. The subjects were categorized in two groups, the hot flush group(37) and normal group(26). For the study, the subjects were selected by excluding the patients who receive treatment affect hot flush or have disease affect arterial states. We assessed PWV and ABI of two groups by Oscillometric method using VS-1000(Form PWV/ABI; Fukuda Denshi, Co., Ltd., Japan). From these results, we studied the correlation between hot flush and PWV/ABI by Wilcoxon Mann Whitney Test. Results: 1. It is shown that hot flush group was no significant correlation with normal group. There is no significant factor among R-PWV, L-PWV, R-ABI, L-ABI. However, L-ABI have shown relatively higher correlation with comparison to the other factors.(p-value<0.05) 2. R-PWV, L-PWV significantly increased in menopause group than in premenopause group though there is no relation to the hot flush. (p-value<0.01) Conclusion: Though the results showed no correlations between Hot flush and PWV/ABI in the Climacteric women, L-ABI showed relatively higher correlation with hot flush than others. R-PWV, L-PWV showed significant correlation between premenopause and menopause.

• The Journal of Korean Obstetrics and Gynecology
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• v.23 no.2
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• pp.131-144
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• 2010

Purpose: There has not been decisional consensus in the concepts and the ways of postpartum cares between Western and non-Western cultures though the importance of postpartum period has been emphasized by the multitude of health professionals. In this study, we investigated the differences in recognition concerning postpartum care among Koreans, Korean residents in America, and Americans (hereafter, K, KA, A). Methods: We used questionnaire of women who had given birth from last 6 weeks to less than 13 years. The women consisted of three groups;104 K, 44 KA, and 44 A. Results: In the perception survey concerning postpartum care, every three group thought that postpartum care was important. However, there were differences in understanding how it would affect women's health, and what they did in the period. K significantly agreed with the content and the importance of postpartum care. The investigation concerning seven categories of postpartum care showed that K group performed the 6 categories except consuming medication beneficial for the postpartum care. KA group performed in a low rate and A group performed two categories in a significantly low rate two categories; avoiding cold stimulation and keeping the body warm. Conclusion: Based on this study, it should be suggested that there were common points and differences among the recognition concerning postnatal care in three groups. Therefore, health professionals make efforts in understanding diversities on postnatal care and providing the adequate services reflecting each mother's needs and recognition.

• The Journal of Korean Obstetrics and Gynecology
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• v.23 no.2
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• pp.154-160
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• 2010

Purpose: This study was done to report the progress of treatment with oriental medicine on a woman who complained of irregular menstruation in menopausal transition. Methods: The patient in this case was treated with Chokyungjongoktanggamibang, acupuncture and moxibustion. And to assess the effectiveness of this treatment, we evaluated the ovarian function by using hormone assay. Results: During treatment period the patient had three times of uterine bleeding, two of the three seemed like normal menstrual bleeding. And analyzing the hormone assay, estraiol level was increased and FSH, LH levels were decreased significantly. However a month after treatment end, estradiol level was decreased and FSH, LH levels were incresead as the levels in menopausal transition or menopause state. And the patient had no more uterine bleeding since last one according to follow up by phone-call. Conclusion: In this study, the progress of ovarian function was specified with hormonal changes after treatment of oriental medicine during menopausal transition. And further studies are needed to find the more appropriate clinical approach for women in menopausal transition.

• The Journal of Korean Obstetrics and Gynecology
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• v.23 no.1
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• pp.83-96
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• 2010

Purpose: A survey was conducted by questionnaire to investigate outpatients' intake status of health food. Methods: The survey of visiting oriental OB&GY clinic in 4 hospitals of oriental medicine and 1 oriental medical clinic has found the status of health food intake. Results: 1. Total respondents were 339(Male: 54, Female: 264) and their average age was $41.4{\pm}11.8$. Outpatients of oriental medicine clinic were 113, outpatients of hospitals of oriental medicine were 226. 2. Among the respondents, 156(40%) persons were taking health food as of today and the proportion of health food intake by oriental medicine clinic's outpatients is higher than the proportion of outpatients of hospitals of oriental medicine. 3. There is no difference in educational background and income among the outpatients who visited the oriental medicine clinic or hospitals of oriental medicine. And the middle income group's health food intake ratio was the highest. 4. The survey showed that heath food intake ratio got higher as persons became old. 5. Among the health foods, the multi-vitamin was most frequently taken. And omega 3, Ginseng steamed red, Vitamin C, Glucosamine, Calcium m were also frequently taken. Conclusion: A study for health food intake status by clinic is indispensable to establish the standard for efficient intake of health food.

• The Journal of Korean Obstetrics and Gynecology
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• v.23 no.2
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• pp.1-19
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• 2010

Purpose: This study was designed to investigate the effects of Gaeullijin-Tang(GIT) on the progression of the estradiol valerate(EV)-induced polycystic ovaries(PCO) in rats. Methods: PCO was induced by single intramuscular injection with estradiol valerate(EV)(4mg) in female rats. Normal group(n=8) were injected with sesame oil and orally administrated distilled water for sixty days. PCO control group (n=8) were injected with EV and orally administrated distilled water for sixty days. GIT treated group(n=8) were injected with EV and orally administrated GIT for same duration. At the end day of experiment, we measured weights of body, ovaries, adrenal glands, uterus and contents of serum androsternedione (ADD) and total estrogen. The histomorphometrical changes of ovaries were also evaluated. And we observed the NGF and CRF expression by immunohistochemistry. Results: The results were as follows - The weights(mg) of ovaries in GIT treated group($75.5{\pm}4.3$) were significantly increased(p<0.001) compared with PCO control group($54.3{\pm}4.5$). - The numbers of mature follicles in GIT treated group($5.3{\pm}1.2$) were significantly increased(p<0.05) compared with PCO control group($3.5{\pm}1.2$). - The numbers of corpora lutea in GIT treated group($1.8{\pm}1.3$) were significantly increased(p<0.05) compared with PCO control group($0.3{\pm}0.7$). Conclusion: From the above results, we concluded that Gaeullijin-Tang(GIT) contributes to stimulating normally ovulation by decreasesing ovarian NGF concentrations.

• The Journal of Korean Obstetrics and Gynecology
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• v.21 no.2
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• pp.214-231
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• 2008

Purpose: The purpose of this research is a comparative study of the actual, the perceptive and the ideal body shape of the obese and non-obese female in their twenties and thirties Methods: The actual, the perceptive and the ideal body shape of the obese female and the non-obese female were collected and statistically analyzed in 25-34 years old. Results: In 25-29 years old the obese group and the non-obese group shows considerable difference in the weight, abdomen, calf circumstance in their actual body shape, but they recognize similar size as their ideal body shape in the hip, thigh and calf circumstances. They recognized that they are fatter than the actual body shape in the thigh, hip, and calf circumstances in common. In 30-34 years old the obese group and the non-obese group shows considerable difference in the weight, upper arm, abdomen, hip, thigh, calf circumstances in the actual body shape, but they recognize similar size as their ideal body shape in the thigh, hip, and calf circumstances. They recognized that they are fatter than the actual body shape in the weight, upper arm circumstances in common. Conclusion: These new data about body shape in 25-34 years women could be adopt as a useful clinical tool for body image related patients such as obesity, PCOD and postpartum patient in Korean women.