• 대한한방부인과학회지
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• 제33권2호
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• pp.77-89
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• 2020

Objectives: The purpose of this study is to analyse current status and treatment of the Korean medicine hospital after chemotherapy in patients with breast cancer. Methods: We investigated the medical records of 21 patients who admitted to Korean medicine hospital after chemotherapy in patients with breast cacner from March 1, 2017 to December 31, 2019. We searched medical records retrospectively and analyzed current status and treatment of Korean medicine hospital. Results: The average age of 21 participants was 52.81±8.38 years and 40s and 50s accounted for 85.6% of the total. After receiving chemotherapy, the average time to hospitalization was 1.87±3.13days and average hospital stay was 9.78±4.14 days. The subjects were classified as 28.6% of stage I, 52.4% of stage II, 9.5% of stage III, and 9.5% of stage IV. The analysis according to the presence of metastasis was 57.1% without metastasis, 33.3% with axillary lymph node metastasis, and 9.5% with distant metastasis. The main symptoms complained when hospitalized by 21 subjects were nausea (54.2%), fatigue (54.2%), and anorexia (50.8%) in over 50%, pantalgia (47.5%), and insomnia (47.5%), dizziness (44.1%), cold sweating (42.4%), lower extremity pain (40.7%), 37.5~37.9℃ fever (39.0%), headache (37.3%), hot flush (37.3%), pruritus (30.5%) are 30% or more. Korean medicine treatment was performed in 87.4% of all hospitalizations and Gwakhyangjunggi-san-gami was the most administered prescription. Extracts of Korean medicine was performed in 100.0% of all patients and Eunkyo-san was most administered extracts medicine. Acupuncture, moxibustion, and cupping treatments were performed in all 21 study subjects. Other treatments was performed at a frequency of hyperthermia (90.5%), lymph massage (23.8%), air compression therapy (23.8%), and Interference current therapy (19.0%) Conclusion: Korean traditional medicine can be used as a countermeasure for side effects after chemotherapy in breast cancer patients.

• 대한한방부인과학회지
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• 제33권2호
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• pp.44-62
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• 2020

Objectives: The purpose of this study is to evaluate the effectiveness of herbal medicine for recovery and treatment of cervical intraepithelial neoplasia (CIN) after loop electrosurgical excision procedure (LEEP). Methods: We searched two english, one chinese and four korean database up to November 4, 2019. Randomised controlled trials (RCTs) were eligible. Primary outcome included Human papilloma virus (HPV) clearance rate and the effective ratio of treatment. And vaginal bleeding time and volume, improvement of symptoms, and recovery of wound were regarded as secondary outcomes. The risk of bias was assessed by two independent authors using the Cochrane risk of bias tool. Results: Of 47 screened, 10 RCTs were included. Number of participants per study ranged from 58 to 360. The studies which used HPV clearance rate as primary outcome were considered as low risk of bias. Most of the studies had considerable heterogeneity in terms of type of intervention, comparison and time-points for outcome measurement. Compared to LEEP alone, herbal vaginal suppository combined group showed favorable results for HPV clearance in patients (5 studies, n=627, 95% CI 1.26 to 1.55, I²=75%). And compared to LEEP alone, herbal external application also showed favorable results for HPV clearance in patients (2 studies, n=252, 95% CI 1.19 to 1.61, I²=86%). Three studies reported mild and temporary adverse events, and no serious adverse events were reported. Conclusions: The studies showed that herbal medicine can significantly effective on recovery of CIN after LEEP. However, included studies suffered from incomplete reporting, high or unclear risk of bias and substantial heterogeneity between studies. In the Future, further high-quality RCTs are needed to prove effectiveness of herbal medicine for CIN after LEEP and reduce the risk of bias.

• 대한한방부인과학회지
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• 제23권1호
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• pp.42-52
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• 2010

Purpose: This report aims to administer methodologic issues around recently conducted multicenter study for evaluating the effects of acupuncture on menopusal hot flashes and discuss practical issues for further implementation of acupuncture clinical trial for hot flashes. Methods: Study process were mentioned, and issues related to avoiding risk of bias, designing appropriate control group, optimal outcome measurement, potential different effects of menopausal status on study outcomes, and suggestions for developing future clinical trials are discussed. Results: Shortcomings of our multicenter study include lack of allocation concealment and assessor blinding, subjective outcome measurement, short-term follow-up, and fixed acupuncture regimen despite pragmatic purpose of this study. Improving trial design, using objective or validated outcomes, assessing long-term effects of acupuncture, and individualizing acupuncture regimen are needed in future clinical trials. Conclusion: We expect these practical discussions to enable researchers to plan and develop future well-designed clinical trials for evaluating the effects of acupuncture on hot flashes or other women's health issues.

• 대한한방부인과학회지
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• 제29권2호
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• pp.83-98
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• 2016

Objectives: This Study was designed to investigate the effect of Oxygen chamber to recover muscle fatigue. Methods: Twenty Subjects were divided into Oxygen Chamber Group (n=10) and Rest group (n=10). Subjects visited hospital two times, blood tests were performed 3 times for each visit. 1st blood test was performed in 4 hours hunger state. 2nd blood test was performed within 5 minutes after the 6 minutes bike exercise. 3rd blood test was performed after the 40 minutes Oxygen treatment or 40 minutes rest in bed. Blood test items were Lactate, Glucose, Lactate Dehydrogenase, Creatine Kinase, Free Fatty Acid. 2nd visit was applied 1st visit process, But Oxygen Chamber group was crossed over to Rest Group, Rest Group was crossed over to Oxygen Chamber group. The Blood test result was analyzed with paired T-test using SPSS for Windows version 21. Results: The reduction of Lactate in Oxygen Chamber Group (6.86±2.07 mmol/ℓ) was higher than Rest group (6.57±2.33 mmol/ℓ), but it was not statically significant (p=0.68). The reduction of Glucose in Oxygen Chamber Group (6.85±12.14 mg/dl) was lower than Rest group (7.60±9.83 mg/dl), but it was not statically significant (p=0.83). The reduction of Lactate Dehydrogenase in Oxygen Chamber Group (16.10±14.91 mmol/ℓ) was lower than Rest group (19.75±12.46 mg/dl), but it was not statically significant (p=0.41). The reduction of Creatine Kinase in Oxygen Chamber Group (13.40±5.69 U/ℓ) was lower than Rest group (15.25±8.01 U/ℓ), but it was not statically significant (p=0.41). The reduction of Free Fatty Acid in Oxygen Chamber Group (285.50±174.13 uEq/ℓ) was higher than Rest group (196.15±131.58 uEq/ℓ), but it was not statically significant (p=0.07). Conclusions: This study showed Oxygen chamber therapy could be effective to recover muscle fatigue.

• 대한한방부인과학회지
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• 제23권2호
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• pp.106-115
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• 2010

Purpose: The purposes of this study were in understanding maternal and neonatal risk factors for postpartum depression using Edinburgh Postnatal Depression Scale(EPDS). Methods: Among 788 women, who had delivery include cesarean section in the department of obstetrics and gynecology at OO medical center from May 28th 2008 to October 6st 2009, 72 women filled out EPDS questionnaire sheets. Additional aspects included for the analysis are maternal factors including age, number of children, parity, delivery method, and hemoglobin; and neonatal factors such as weight, sex, gestational age, apgar score, and neonatal intensive care unit admission. Comparison was performed between the women with EPDS score equal or less than 8 and the women with EPDS score equal to or higher than 9 using statistical methods of student t-test for linear variables and chi-square test for non-linear variables. SPSS version 13.0 for windows was used for analysis. Results: Thirty women(41.7%) were included in the postpartum depression risk group (EPDS score ${\geqq}9$). Statistically significant difference(P<0.05) was found in gestational ages of the risk group($36.57{\pm}29.6$ weeks) and the non-risk group ($38.10{\pm}1.97$ weeks). Identified statistically significant risk factors(P<0.05) include cesarean section (OR=3.304 [1.121-9.744]), low birth weight infant(OR =6.500 [1.606-26.314]), preterm delivery(OR=2.857[1.071-7.621]), low apgar score (1minute) after delivery (OR=14.909 [1.750-127.025]). There was no statistically significant difference in maternal age, number of children, parity, hemoglobin, neonatal sex, apgar score (5minutes), NICU admission. Conclusions: Through the results showed, gestational age, delivery method, neonatal weight, apgar score(1minute) were identified as risk factors for postpartum depression. To prevent or minimize postpartum depression, oriental medical intervention is recommended for pregnant women through early detection.

• 대한한방부인과학회지
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• 제23권2호
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• pp.38-56
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• 2010

Purpose: This study was designed to evaluate the effect of administration of Foeniculi Fructus on ovarian functions and differential gene expressions related cell viability such as caspase-3, MAPK and MPG in female mice. Methods: We administered the Foeniculi Fructus to 6-week-old female CF-1 mice for 4, 8, 12 days. After administration of Foeniculi Fructus with 0.1, 1, 10, $100\;mg/m{\ell}$ concentration in the comparison of control group with $0\;mg/m{\ell}$, we observed the mean number of total ovulated oocytes and the number of morphologically normal oocytes. After entosomatic fertilization, we observed the rate of fertilized 2-cell embryos to blastocyst stage in vitro. Also we chose the caspase-3 for cell apoptosis, MAPK and MPG genes for cell viability and DNA repair by RT-PCR. Results: 1. In case of 4, 8, 12day administration of Foeniculi Fructus with 0.1, 1, 10, $100\;mg/m{\ell}$, the mean number of total ovulated oocytes and the number of morphologically normal oocytes were increased in the comparison of control group. 2. In case of 4, 8, 12day administration of Foeniculi Fructus with 0.1, 1, 10, $100\;mg/m{\ell}$, the rates of blastocyst formation from 2-cell stages were increased in the comparison of control group. 3. In case of 4, 8, 12day administration of Foeniculi Fructus with 0.1, 1, 10, $100\;mg/m{\ell}$, the gene expression of caspase-3, MAPK, MPG didn't show significant result in the comparison of control group. Conclusion: This study shows that Foeniculi Fructus has significant effects on the increase of the function on ovulation and embryonic development of female mice. But this results have nothing to do with caspase-3, MAPK and MPG genes. So we need a further study for which genes are related to the activation of reproductive functions of Foeniculi Fructus.

• 한국산림과학회지
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• 제90권3호
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• pp.338-345
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• 2001

본 연구는 독일가문비나무의 지하부인 뿌리구조와 지상부인 수관과의 상호관계를 밝혀, 어렵게 뿌리를 굴취하거나 침엽 생체량을 측정하지 않고도 수고와 흉고직경에 의한 상대적인 뿌리와 침엽 생체량 추정을 위한 회귀식을 구하기 위하여 실시하였다. 독일 중부 Harz 지방의 Barbis 임분에서 30~40년생의 우세목 5본과 준우세목 3본을 선발한 후 조사목의 지상부에 대하여 수고, 흉고직경, 지하고, 침엽량, 가지량, 횡단면, 변재면 등을 조사하였다. 그리고 5본에 대해서는 지하부의 뿌리길이, 뿌리수, 뿌리무게, 뿌리횡단면 등을 수평과 수직뿌리로 구분하여 조사하였다. 조사된 염분에서 독일가문비나무의 지상부(수고, 흉고직경, 침엽량, 가지량 등)와 지하부(뿌리길이, 무게, 수, 횡단면 등) 생체량 사이에는 서로 밀접한 상관을 나타내었다. 측정이 용이한 흉고직경에 대한 지하부 뿌리생체량은 Y = 3.56X - 45.94의 관계식으로 결정계수가 0.96으로 매우 높은 상관관계를 나타내었다. 가지량, 침엽량과 수고에 있어서도 지하부 생체량과 높은 상관관계를 나타내었다. 본 연구에서 얻어진 회귀식은 30~40년생 독일 가문비나무 임분에서 흉고직경을 이용하여 지하부의 상대적인 뿌리 생체량을 추정하는데 유용하게 이용될 수 있을 것이다.

• 조형예술학연구
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• 제9권
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• pp.89-115
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• 2006

한국근대미술은 유화 도입기인 1910년대를 한국미술사의 중요한 시작점이다. 1910년경부터 형성되기 시작한 유화 도입배경과 그것이 당시 사회의 절실한 요청에 의한 것이었는지, 그렇다면 그것이 무엇인지 규명하는 것이 한국근대미술 초기를 알 수 있는 중요한 문제일 것이다. 일본근대 유화의 역사는 국수주의와 서구주의 물결이 반복하는 과정에서 점차 일본화된 소재의 등장과 일본정서에 부합하는 화풍을 만들어 나가게 되는 것이 1890년대부터 1910때까지의 일본근대 유화계의 상황이라고 할 수 있다. 이 시기를 다시 요약하면 외광파와 인상파가 절충된 양식에 일본의 메이지낭만주의에 부합하는 소재 즉 일본전통이라고 할 수 있는 풍경에 대한 애착 등이 전체 유화의 기류로 나타나는 시기라고 할 수 있다. 실제 새로운 문화의 하나였던 유화는 점차 세계의 다양한 미술사조 속에서 일본화다운 것으로 발전하는 모습을 보여준다. '구로다 세이키'(黑田淸輝) 이전에 이미 형성되었던 일본근대 유화양식과 구로다의 외광파 양식, 또 외광파가 일본 근대유화의 주류로 형성하게 되는 계기, 여기에 프랑스에서 직접 배워 온 작가들에 의한 인상파 도입 그리고 일본 '메이지낭만주의'(明治浪漫主義)의 등장으로 인한 사회 환경구조의 변화 속에서 양성된 그들의 절충양식의 초기유학생들에게 큰 영향을 미쳤다. 우리근대미술은 '민족적 자부심'과 '민족적 열등감'이 동시에 존재하는 사회적 배경논리에서 출발하지 않으면 안 된다. 즉 근대미술의 사상적 배경에는 민족 개량주의적 발상과 계몽주의적 문화 활동에 있었다고 할지라도 근본적으로는 미술자체를 근대사회 발전의 연장선 속에서 파악하지 못했고, 따라서 미술자체를 새로운 문명수입이라는 근대적 풍물 정도로만 파악했던 것이 어쩔 수 없는 근대미술의 한계라고 할 수 있다. 이 시기에 미술을 주목한 이유는 근대적 사회로 발전하기 위한 하나의 필수적인 요소로 미술자체를 파악하고 나아가, 식산흥업(殖産興業)의 수단으로 인식 했던 신지식층에 의해 시작되었다고 할 수 있다. 문명의 발달이 미술의 발달에서 연원한다는 '미술문명론' 같은 시각이 미술자체가 성격이나 창작의 방향과는 무관하게 어떤 미술이든 그것을 활성화시키는 것이 근대 즉 문명화된 세계로 나아갈 수 있다고 하는 관점에서 비롯된 것이라고 할 수 있다. 한국근대미술에 있어서 아카데미즘 역시 일본근대미술과 불가분의 관계가 있음을 부인할 수 없다. 초기유학생들은 그 당시 일본의 잡지나 화단에서 일어나는 여러 가지 시안들을 피상적으로 이해하는 정도였을 것으로 파악할 수 있다. 이러한 맥락에서 보면 한국근대미술에 있어서 초기유학생들의 작품과 그 이후 선전에서 입선하는 작품들은 일본아카데미즘의 영향 밑에 있다고 해야 할 것이다. 일본 근대 유화에서 형성된 외광파의 요소와 인상파 요소들이 일본 낭만주의로 표면화된 하나의 일본근대 유화의 형식 그대로가 한국아카데미즘의 성격을 결정하고 있다고 할 수 있다. 게다가 1922년에 시작된 선전은 심사위원 대부분이 동경미술학교 교수이면서 구로다의 제자이거나 동료였다는 것은 이러한 사실을 더욱 확고하게 뒷받침하고 있는 것이다. 초기유학생들이 남긴 작품들은 완전한 인상파에 대한 지식이나 깊은 자아의식을 가지고 제작된 것은 아니라, 일본 동경미술학교에서 가르치고 있었던 것들을 그대로 수용했다고 할 수 있다. 따라서 이들의 그림은 구로다의 외광파라고 부르는 것들의 영향보다는, 인상파를 보고 배웠던 동경미술학교 교수들의 영향을 더 많이 받았다고 할 수 있다. 그리고 이들의 영향은 그대로 한국 근대미술의 아카데미즘을 형성하는데 커다란 영향을 미치고 있음을 부인할 수 없다.

• 대한한방부인과학회지
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• 제31권3호
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• pp.97-108
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• 2018

Objectives: This survey was conducted to investigate the satisfaction level of the project of providing free herbal medicines to mothers living in Suncheon who gave birth to more than three. Methods: Using the online survey tool Survey Monkey, the mother was sent a questionnaire in a cell phone text to answer the questions on their cell phones. The mothers' contact information was based on the application form for a woman with three or more children, and a total of 27 people were surveyed and 20 responded. Results: The lowest level of satisfaction was 51 percent, the highest level of satisfaction was 100 percent, and the average was 86 percent. Conclusions: As the satisfaction level of the free herbal medicine support program is generally high, it is necessary to maintain the business continuously. And if other oriental medicine treatment is applied, more positive effect can be expected.

• 대한한방부인과학회지
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• 제31권3호
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• pp.1-19
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• 2018

Objectives: The purpose of this study was to analyze the research trends of randomized controlled trials on Traditional Korean Medicine treatment for postpartum depression in women. Methods: In order to investigate the effect of Traditional Korean Medicine on postpartum depression, randomized controlled trials on postpartum depression were searched using domestic and foreign search engines and a total of 11 studies were selected. Results: 1. There were 6 studies comparing Traditional Korean Medicine treatment methods with western medicine: fluoxetine hydrochloride (4), paroxetine (1), and mirazapine (1). 2. There were 5 studies comparing methods of Traditional Korean Medicine or sham acupuncture: 1 study evaluated the efficacy of Balance Acupuncture and Guipi Decoction, 1 study compared the effects of conventional acupuncture and Dispersing Liver Regulating Spirit Acupuncture, 1 study evaluated the efficacy of acupuncture and Heat-sensitive Moxibustion, 1 study compared the effects of conventional acupuncture and Musical Electroacupuncture, and 1 study compared the effects of conventional acupuncture and non-invasive sham acupuncture. 3. Postpartum depression is closely related to Heart and Liver, and there were many studies using acupoints Taichong (LR3) and Shenmen (HE7). Cranial acupoints Baihui (DU20) and Yintang (EX-HN3) were also frequently used. 4. Xiaoyaosan and Guipi Decoction were used in herbal medicine treatment for postpartum depression. 5. Novel treatment methods such as Heat-sensitive Moxibustion and Musical Electroacupuncture were used to treat postpartum depression. Conclusion: Traditional Korean Medicine treatment is a good treatment option for postpartum depression. Further systematic studies are needed to establish the basis for Traditional Korean Medicine treatment for postpartum depression.