• Title/Summary/Keyword: 부가적 손상

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Antioxidant Activity and Inhibitory Effect on Oxidative DNA Damage of Ethyl Acetate Fractions Extracted from Cone of Red Pine (Pinus densiflora) (솔방울 에틸아세테이트 분획물의 항산화 및 산화적 DNA 손상 억제 활성)

  • Jang, Tae Won;Nam, Su Hwan;Park, Jae Ho
    • Korean Journal of Plant Resources
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    • v.29 no.2
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    • pp.163-170
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    • 2016
  • Antioxidant activity and inhibitory effect on oxidative DNA damage of ethyl acetate fractions extracted from Cone of Red Pine (Pinus densiflora) were investigated to find utilization of Cone, by-product of Red Pine, thrown out after berry shatter, as a new natural plant resource. Cone from P. densiflora was extracted with methanol (MeOH) and separated to petroleum ether, ethyl acetate and water fraction. Among them, ethyl acetate fraction was used. The antioxidant activity was conducted by the 1,1-diphenyl-2-picryl hydrazyl (DPPH) radical, 2, 2'-Azino-bis (3-ethylbenzothiazoline-6 sulfonic acid) diammonium salt (ABTS) radical scavenging assay, Fe2+ chelating assay and reducing power assay. The inhibitory effect on oxidative DNA damage was determined by DNA cleavage assay using φX-174 RF I plasmid. The results of DPPH and ABTS radical scavenging activity at 200 ㎍/㎖ of extracts were 86.50% and 95.80% respectively, which were similar figures compared with L-ascorbic acid as control. Fe2+ chelating activity was 77.96% and reducing power was 0.77 at 200 ㎍/㎖. Total phenolic component was 27.29±0.3 ㎎/g and Vitamin C content was 1.84±0.1 ㎎/g. Also ethyl acetate fraction from Cone has inhibitory effect, using φX-174 RF I plasmid on DNA cleavage assay. In conclusion, Cone, by-product of P. densiflora, showed high antioxidant activity and inhibitory effect on oxidative DNA damage. Therefore this study suggests Cone, useless by-product, can be developed as a new natural plant resource with lots of utilization such as an effective antioxidant, natural medicine, food, cosmetics and so on.

Clinical Analysis of Fractures by Inline Skating Injury (인라인 스케이트시 발생된 골절의 임상적 고찰)

  • Choi Hyung Suk;Doh Hyun Woo;Lee Byung Ill;Min Kyung Dae;Rah Soo Kyun;Kim Yeon Ill;Seo Yoo Sung
    • Journal of Korean Orthopaedic Sports Medicine
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    • v.3 no.1
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    • pp.87-91
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    • 2004
  • Purpose: The purpose of this study is to investigate the incidence and patterns of fractures occurred in Inline skating accident. Materials and Method: We evaluated 20 patients, 20 cases(from september 2002 to August 2003) with fractures occurred during Inline skating. The incidence, sex, age, fracture site, associated injuries, causes of Inline skating injuries were analysed. The cases were male in 18(90$\%$), and female in 2(10$\%$). The most common distribution of age was in twenties and thirties. Result: The patients(12cases 60$\%$) with upper extremity fracture were more common than patients(8cases 40$\%$) with lower extremity fracture. Patients who had fracture in ankle were 35$\%$(7cases), forearm 20$\%$(4cases), wrist 20$\%$(4cases), elbow 15$\%$(3cases), thigh 5$\%$(1cases). According to the The Lauge-Hansen classification in ankle fractures there were four patients of supination-external rotation type, two patients of supination-abduction type, and 1 patient of pronation-external rotation type. In forearm and hand fractures, there were three distal radius fractures, one radio-ulnar shaft fracture, 2 scaphoid fractures, and two meta-carpal fractures. In elbow fractures, there were two supracondyle fractures, and one lateral condyle fracture. There were three epiphyseal plate injuries (Salt-Harris type II) in children, and all of them were treated by conservative method. Six fractures were intra-articular fractures. The most common associated injury was contusion(8cases 42.1$\%$). The number of patients who only rode Inline skating less than 3months(8cases 40$\%$) was the greatest. The number of non-contact injury(14cases, 70$\%$) in Inline skating was more than contact(6cases,30$\%$) injury. 11cases(55$\%$) had operative treatment, and 9cases(45$\%$) had conservative treatment, and there was not any complication. The more detailed study is required since the materials were only limited to fracture patients, and the follow up period was short. Conclusion: The most common age for fracture in Inline skating was in twenties, and thirties, and ankle was the most common fracture site.

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Low Temperature Structural Tests of a Composite Wing with Room Temperature-Curing Adhesive Bond (상온접합 본딩이 있는 복합재 날개의 저온 구조시험)

  • Ha, Jae Seok;Park, Chan Yik;Lee, Kee Bhum
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.43 no.10
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    • pp.928-935
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    • 2015
  • This paper presents low temperature structural tests of a UAV wing which has room temperature-curing adhesive bond. The wing structure is made of carbon fiber reinforced composites, and the skins are bonded to the inner structures (such as ribs and spars) using room temperature-curing adhesive bond. Also, to verify damage tolerance design of the wing structure, barely visible impact damages are intentionally created in the critical areas. The attachment fittings of the wing are fixed in a specially designed chamber which can simulate the low temperature environments of the operating altitudes. The test load is applied by hydraulic actuators which are placed outside the chamber. The structural tests consist of strain survey tests and a durability test for 1-life fatigue load spectrum. During the tests, strains of major parts are measured by strain gauges and FBG sensors. The change of the initial impact damages is also monitored using piezoelectric sensors. The 1-life damage tolerance of the composite structure is verified by the structural tests under the simulated environments.

Effects of Formula (JR-22) Maybe Containing Traditional Herbs on Maximal Exercise Performance and Antioxidant Meterials in Murine Model (생약조성물 투여가 지구력 향상과 항산화 물질에 미치는 영향)

  • 홍성길;양동식;강봉주;이홍석;윤유식
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.32 no.7
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    • pp.1076-1081
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    • 2003
  • The effects of dietary supplementation of JR-22, formula containing distilled extracts of traditional herbs on maximal exercise performance and endurance were evaluated in mouse and rat model. In acute forced swimming test with 4%∼8% of the body weight attached to the tail, it was shown that dietary JR-22 supplementation increased endurance in exercise performance. There was no change of blood lactic acid, ammonia, inorganic phosphorous ion and creatine kinase activity, however ATP concentration in muscle was increased by JR-22 supplementation. Also, insulin-like growth factor-l (IGF-1) concentration in blood was significantly increased by JR-22 supplementation. In addition, the oxidative damage induced by exercise was reduced by JR-22 supplementation. In these results, we suggested that JR-22 supplementation enhanced maximal endurance exercise performance by the mechanism of increasing ATP and IGF-1 concentration and reducing oxidative damage.

프로펠러 보호터널 부착 연안어선 개발에 관한 연구

  • 고재용
    • Journal of Korea Ship Safrty Technology Authority
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    • v.17
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    • pp.24-43
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    • 2005
  • 최근 우리나라 어선어업은 한중일 어업협정, 연안 어업자원 감소 및 연안오염 등 사회적, 환경적 변화가 급변하고 있어 이들을 고려한 어선 선형개발이 필요로 한다. 현재 우리나라의 어선 중 연안지역에서 조업하는 5톤 미만의 소형어선은 전체 어선 중 $65\%$ 이상으로 구성되어 있으나 선박의 크기가 작고 부가가치가 낮은 관계로 지금까지 전문적인 연구는 거의 없었던 것이 현실이다. 한편, 서$\cdot$남해 연안에서 작업 및 항해하는 연안어선들의 해양사고 발생율은 전체사고의 $69.6\%$로 매년 증가하고 있는 추세이다. 전체 어선 안전사고 중 부유폐어망, 로프 등이 추진기에 감긴 사고는 전체 사고의 $10.4\%$로 매년 증가하고 있다. 이에, 추진기 손상에 의한 어선 사고와 연관하여 추진기를 보호하기 위한 장치로서 물분사 추진기(Water-Jet), 펌프제트(Pump-Jet)장치들이 있으나 이들은 고가 수입품으로서 영세한 어민들의 소형어선에 장착하기에는 한계가 있어, 본 연구에서는 폐그물, 로프 등 해상 부유물에 의한 추진기 손상이 발생되지 않는 프로펠러 보호터널 부착 추진장치를 개발을 목적으로 한다. 프로펠러 부착 추진장치는 기존 선미를 수정하여 추진기를 선체 안쪽으로 배치하며 돌출되는 부분은 덕트로 보호하고 있으며 이러한 추진기는 워터제트 추진기와는 달리 가격이 싸고 그물이나 부유물에 걸리지 않고 고장 시 신속한 대응이 쉬워 소형 연안어선에 적합할 뿐만 아니라 그물, 부유물, 갯벌이 많은 국내의 서$\cdot$남해 연안에서 작업 및 항해 시 매우 유용할 것으로 판단된다. 본 연구는 `프로펠러 보호터널 부착 연안어선의 선형개발`을 최종목표로 수행하였으며, 연구개발 내용은 기존 소형 연안어선의 분류 및 특성 조사 연구, 프로펠러 보호터널형 선미 선형 개발, 기존 선형 및 보호터널형 선형의 모형시험, 개발선의 구조강도 특성, 프로펠러 설계 및 단독시험, 보호터널 부착 추진기의 효율 검증 및 개발 대상 어선의 조선공학적 제 계산, 설계도작성 등을 실시하였다. 주요 요소 기술로서는 프로펠러 보호터널 부착 선형의 모형시험을 통하여 선미선형을 개발하며 FRP판부재의 구조강도 특성을 분석하고 그 결과를 활용하여 4톤급 연안어선의 시제선을 건조하고 시운전을 통하여 주요성능을 확인하였다.

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Double-bundle Anterior Cruciate Ligament Reconstruction using Autogenous Hamstring Grafts (이중 다발 자가 슬괵건을 이용한 전방십자인대 재건술)

  • Choi, Nam-Yong;Nam, Won-Sik;Yang, Young-Jun;Han, Chang-Hwan;Moon, Chan-Woong;Kwon, Jae-Young;Song, Hyun-Seok
    • Journal of the Korean Arthroscopy Society
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    • v.12 no.2
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    • pp.112-117
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    • 2008
  • Purpose: Double-bundle reconstruction of anterior cruciate ligament(ACL) has the advantage of restoring the isometry and original function of ACL. The purpose of this study is to evaluate the clinical results following double-bundle reconstruction of ACL using autogenous hamstring grafts through an accessory anteromedial portal. Materials and Methods: From January 2005 to July 2006, sixty patients(52 males, 8 females) underwent double-bundle ACL reconstruction using autogenous hamstring tendons..The mean age was 31.7 years($20{\sim}51$ years). The mean follow up period was 13.4 months($12{\sim}16$ months). We made a horizontal-oblique skin incision just medial to tibial tuberosity and harvested semitendinosus and gracilis tendon. Tibial tunnel for posterolateral bundle was made near its anatomical position. By modifying an anatomic reconstruction of ACL by Yasuda et al., we made a femoral tunnel for posterolateral bundle through accessory anteromedial portal. Tunnels for anteromedial bundle were made with conventional method. We reconstructed anteromedial bundle with semitendinosus tendon and posterolateral bundle with gracilis tendon. Clinical results at last follow up were evaluated by range of motion, extent of anterior displacement(KT-1000 arthrometer), pivot-shift test. Functional evaluation of clinical outcomes were evaluated by Lysholm score and modified Feagin Scoring System. Results: There was no limitation of motion of knee joint at last follow up. Mean side to side difference of anterior displacement of tibia by KT-1000 arthrometer was improved from 8.4 mm preoperatively to 1.7 mm postoperatively(p<0.05). Average Lysholm score was improved from 64.1 preoperatively to 92.2 postoperatively(p<0.05). In modified Feagin Scoring System, 90% of cases were rated as good or excellent. Conclusion: Double-bundle reconstruction of ACL using autogenous hamstring grafts through accessory anteromedial portal results in good clinical outcomes.

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스타트업 제품 모델링을 위한 기존 보급 제품의 품질 유형 분류

  • Choe, Jae-Hun;Kim, Pan-Su
    • 한국벤처창업학회:학술대회논문집
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    • 2021.11a
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    • pp.161-165
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    • 2021
  • 스타트업 제품 모델링에 있어 기존 제품에 대한 분석은 매우 중요한 역할을 한다. 그리고 이러한 분석은 다양한 방식과 프로그램 들을 통해 측정이 가능하다. 하지만, 다수의 스타트업들은 이러한 프로그램 운영이나 통계적 산출을 할 수 있는 인력 공급이 원활하지 않아 실제 사용에 많은 어려움을 겪고 있다. 이에 본 연구는 특별히 뛰어난 수리적 지식이 없더라도 중, 소 스타트업의 입장에서 직원 누구나 활용 가능한 제품 분석 방법에 대해 찾게 되었으며 그 결과 Kano 모형이 가장 적합할 것이라는 예측을 하였다. Kano 모형을 적용할 제품군으로는 많은 소비자가 존재하지만 시장이 크지 않아 진출 기회가 열려있는 스마트워치를 대상으로 하였다. 본 연구에서는 일반적으로 많은 회사에서 활용하고 있는 기본 오피스 프로그램인 EXCEL만을 활용해 제품의 Kano 모델 측정을 진행하였으며 그 결과 매력적요소 4가지(배터리 유효기간, 워치페이스의 종류와 수, 외형의 손상방지, 브랜드이미지), 일원적요소 13가지(단말기의 무게, 단말기의 외형, 구매가격, 오류발생, 스마트페이 기능, A/S용이성, 사용 가능한 앱의 수, 충전의 용이성, 방수 등 부가기능, 단말기 색상의 다양성, 헬스케어, 통화기능, 알림기능), 당연적요소 1가지(자사 기기와의 연동), 무관심요소 2가지(워치밴드의 디자인, 타사 기기와의 연동) 항목들을 측정하는 것이 가능하였으며 향후 본 Kano 모델을 활용하거나 해석함에 있어 최종학력, 전공, 연령 등이 어떠한 영향을 미치며 모델 사용에 필요한 최소 지식 수준에 따른 추가적인 연구를 진행할 것이다.

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Chronic Injuries and Types of Injuries Related to Adolescent Taekwondo Athletes (성장기 태권도 선수의 만성 통증과 손상 유형)

  • Kim, Ha-Kyung;Kim, Chang-Yoon;Shim, Hee-Jong;Park, Sung-Min;Bae, Byung-Jo
    • Journal of Korean Orthopaedic Sports Medicine
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    • v.8 no.1
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    • pp.46-50
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    • 2009
  • Purpose: This study was designed to analyze? the chronic pain of adolescent Taekwondo athletes, to research the understanding about chronic pain of coaches and athletes, to? reduce the development of chronic pain. Materials and Methods: From March. 2006 to June 2007, 210 athletics and 12 coaches of elementary, middle and high school in Kwang-ju city were surveyed. They was evaluated by physical examination, simple radiographs and MRI. Results: In 210 athletics, 162(77.1%) athletes had chronic pain. 19(11.7%) athletes had over three regions of pain, 74(45.7%) athletes had two regions of pain, 69(42.6%) athletes had one region of pain. In 274 cases of 164 athletes, the most common region was foot and ankle(145 cases, 52.9%), followed by hand(47 cases, 17.2%) and knee(38 cases,13.9%), hip(25 cases, 9.1%), and lumbar area(19 cases, 6.9%) The chronic pain was classified by injury type. Contusion of foot was 103 cases(most common), sprain of ankles was 40cases, Contusion of hands and wrists was 28 cases, and so on. The etiologies of injury that causes the chronic pain were match injury in training that is most common, intensive exercise and match injury in competition. Conclusion: The chronic pain was common in adolescent Taekwondo athletes. The ankle and foot were the most common region of chronic pain and the match injury was the most common injury, caused the chronic pain. Although athletes had considerable mental stress about chronic pain, the treatment of chronic pain and rest were insufficient. Therefore the variable effort to prevent injury and to treatment injury must be considered importantly.

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The Usefulness of Bone Scan in Electric Burns (전기화상에서 골스캔의 유용성)

  • Kim, Tae-Hyung;So, Yong-Seon;Kweon, Ki-Hyeon;Han, Sang-Woong;Kim, Seok-Hwan;Kim, Jong-Soon;Han, Seung-Soo
    • The Korean Journal of Nuclear Medicine
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    • v.30 no.1
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    • pp.130-138
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    • 1996
  • Bone scan is known to be an effective tool for observing the state of soft tissues and bones of electric burn patients. It is also used for observing the progress of patients after debridement or skin graft as well as deforming to amputate specific body parts. To evaluate bone scan's role in electric burn, we analyzed bone scan 37 patients with electric burn. Among the 37 patients, 8 of 37 were injured in low voltage and 29 of them in high voltage. 27 patients received the electrical input through the hand, 6 through the scalp, 2 through the shoulder, 1 through the left chest wall and 1 through the left inguinal area. Among 29 patients received high voltage, 22 patients had the electrical output through the foot, 3 through the hand, 2 through the shoulder, 1 through the buttock and 1 through the left chest wall. Bone scans revealed cellulitis in 37 patients with 47 sites, osteomyelitis in 15 patients with 15 sites & bone defects in 4 patients with 4 sites. In 4 patients with skin graft or skin flap, follow up bone scan showed improvements of bony uptake in preoperatively bony defect area and all of them were healed without complication. There were 2 cases in which uptake increased in the myocardium, 1 in the liver and 6 in the kidney, however, serum calcium level, EKG, cardiac enzyme, liver and renal function tests were normal. In conclusion, bone scans are helpful in the assessment of injury sites after electrical insult and in differential diagnosis of cellulitis and osteomyelitis. It is also useful tool of assessment after skin graft or skin flap, however, it should be further evaluated about internal organ damage.

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Efficient Motion Compensated Extrapolation Technique Using Forward and Backward Motion Estimation (순방향과 역방향 움직임 추정을 이용한 효율적인 움직임 보상 외삽 기법)

  • Kwon, Hye-Gyung;Lee, Chang-Woo
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.36 no.4C
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    • pp.207-216
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    • 2011
  • Motion compensated extrapolation (MCE) techniques show inferior performance compared to motion compensated interpolation techniques, since only past frames are used in MCE. MCE techniques are used for the reconstruction of corrupted frames, the up-conversion of frame rates and the generation of side information in the distributed video coding system. In this paper, the performance of various MCE techniques are evaluated and an efficient MCE technique using the forward and backward motion estimation is proposed. In the proposed technique, the present frame is extrapolated by averaging two frames which are generated by forward and backward motion estimation respectively. It is shown that the proposed method produces better PSNR results and less blocking phenomena than conventional methods.