• Journal of the Society of Cosmetic Scientists of Korea
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• v.28 no.3
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• pp.7-39
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• 2002

The extensive variation in human cutaneous pigmentation is mainly due to differences in the rate of melanin synthesis by epidermal melanocytes, the relative amounts of eumelanin and pheomelanin synthesized, and the manner and rate of transfer of melanosomes from melanocytes to keratinocytes. Pigmentation is a complex trait that is regulated genetically and environmentally. One gene that has been receiving a lot of attention is the gene for the melanocortin 1 receptor The extensive polymorphism of this gene in human populations suggests its significance in the diversity of pigmentation. Exposure to solar ultraviolet radiation (UV) results in increased synthesis of a variety of growth factors, cytokines and hormones, and in modulation of their receptors in the epidermis. Knowledge about the regulation of pigmentation has led to strategies for clinical treatment of hyperpigmented skin lesions. Three main strategies are: 1) the use of chemicals that interfere with the melanin synthetic pathway, 2) the design of peptides or peptide-mimetics based on the structure of hormones that regulate eumelanin synthesis, and 3) the use of agents that reduce melanosome transfer from melanocytes to keratinocytes. All three strategies are expected to induce hypopigmentation, by inhibiting total melanin synthesis, eumelanin production, or the epidermal melanin unit, respectively.

• Journal of Digital Contents Society
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• v.18 no.1
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• pp.149-158
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• 2017

Big data have been presenting us with exciting opportunities and challenges in economic development. For instance, in the agriculture sector, mixing up of various agricultural data (e.g., weather data, soil data, etc.), and subsequently analyzing these data deliver valuable and helpful information to farmers and agribusinesses. However, massive data in agriculture are generated in every minute through multiple kinds of devices and services such as sensors and agricultural web markets. It leads to the challenges of big data problem including data collection, data storage, and data analysis. Although some systems have been proposed to address this problem, they are still restricted either in the type of data, the type of storage, or the size of data they can handle. In this paper, we propose a novel design of a platform for collecting and analyzing agricultural big data. The proposed platform supports (1) multiple methods of collecting data from various data sources using Flume and MapReduce; (2) multiple choices of data storage including HDFS, HBase, and Hive; and (3) big data analysis modules with Spark and Hadoop.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.12 no.2
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• pp.959-969
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• 2011

The purpose of this study is to analyze the present conditions of the pilotis spaces of the public apartment housing and to suggest the future planning means of the spaces. At the present time, most of the pilotis space has been constructed in wall-bearing method. However, post and beam method(or Rahmen) will be used due to the municipal public-housing policy. Observation of seven(7) different locations and twenty-eight(28) blocks, and interview with the residents were employed to gather the data. Regarding functional relevance, six types of the space were selected, and planning suggestions for each type were followed. Among others, the conclusions include: the pilotis space should be planned as an interior for the future, as well as it should be open enough to secure the view from the surroundings.

• Economic and Environmental Geology
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• v.51 no.5
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• pp.401-407
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• 2018

For the treatment of heavy metals in the mine drainage from the closed mine area, various methods such as passive, active and semi-active treatments are considered. Among contaminated elements in the mine drainage, Mn is one of the difficult elements for the treatment because it needs high pH over 9.0 for its concentration to be reduced. In this study, the efficiency of various slag complex reactors (slag (S), slag+limestone (SL) and slag+Mn coated gravel (SG)) on Mn removal in the presence of Fe, which is a competitive element with Mn, was evaluated to investigate effective methods for the treatment of Mn in mine drainage. As a result of experiments on Mn removal without Fe during 358 days, using influent with $30{\sim}50Mn{\cdot}mg/L$ and pH 6.7 on the average, S reactor showed continuously high Mn removal efficiency with the average of 99.9% with pH 8.9~11.4. Using the same reactors, Mn removal experiments with Fe during 237 days were conducted with the influent with $40{\sim}60Mn{\cdot}mg/L$. The pH range of effluent reached to 6.1~10.0, which is slightly lower than that of effluent without Fe. S reactor showed the highest range of pH with 7.1~9.9, followed by S+L and S+G reactor. However, the efficiency of Mn removal showed S+L>S>S+G with the range of 94~100%, 68~100% and 68~100%, respectively in spite of relatively low pH range. S+L reactor showed the most resistance on Fe input, which means other mechanisms such as $MnCO_3$ formation by the carbonate prouced from the limestone or autocatalysis reaction of Mn contributed to Mn removal rather than pH related mechanisms. The evidence of reactions between carbonates and Mn, rhodochrosite ($MnCO_3$), was found from the X-ray diffraction analysis of precipitates sample from S+L reactor. From this study, the most effective reactors on Mn removal in the presence of Fe was S+L reactor. The results are expected to be applied for the Mn containing mine water treatment in the presence of Fe within the relatively low range of pH.

• Journal of the Mineralogical Society of Korea
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• v.20 no.4
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• pp.339-349
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• 2007

For various types of the Pungchon limestone, diverse mineral characters of the limestone including their size and morphology are investigated by using of ELS and SEM to examine the possibility of application as fillers to paper industry. Also, the measurement of zeta potential and the evaluation of coagulation properties in calcite suspension was made for fine powders of the limestone to examine the applicability and efficiency in wet-papermaking process. Fine powder of the Pungchon lime-stone, largely controlled by original mineral characters of ore in mineralogical aspects, exhibits some-what different trend in particle morphology according to ore types, and thereby, the size distribution, zeta potential and coagulation properties also become different. The examined whiteness, brightness, opacity and sheet strength in hand sheet also show remarkable differences according to ore types. These are seemed to be basically due to the results of combined effects of whiteness, site distribution, refractive index, and morphology of the limestone powder on the properties of hand sheet. Considering the investigated results, all types of the Pungchon limestone appear to be sufficiently applicable to paper industry. Especially, the mega-crystalline calcite type is evaluated to be overall suitable for the purpose of paper industry due to the higher values in whiteness and brightness. In addition the fine powder of micro-crystalline calcite type is assessed particularly to have a good quality in sheet strength by virtue of irregular particle shape.

• Proceedings of the Materials Research Society of Korea Conference
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• 2009.11a
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• pp.17.1-17.1
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• 2009

발포금속은 1948년에 Sosnik에 의해 알루미늄에 수은을 증발시키는 방법으로 발포 알루미늄을 제조한 이래, 1951년 Elliot에 의해 진보된 방식인 발포 매개체를 용탕에혼입하는 방법으로 발포금속을 제조하기 시작하였다. 현재 이들 선진국가의 생산방법 및 현황은 균질 기공의 조절, 연속주조 방식과 원가절감, 그리고 제조기술의 진보를 통하여 다양한 분야에 적용되고 있다. 그러나 실용화를 위해서는 요구특성을 만족하고 동시에 가격 경쟁력을 가진 제조기술의 보유 및 개발과 독특한 특성을활용한 새로운 적용 분야의 개척이 필요하다고 생각되며, 이를 위해 Harvard, MIT, Aachen, HMI 등 구미 유수 대학과 NASA, 미국방성등의 연구기관, ERG, 신강(新鋼) wire등 산업체를 중심으로제조 및 특성평가에 관한 기초연구와 활용방안이 활발히 모색중에 있다. 그리고 일부 자동차 생산 업체를중심으로 발포금속을 적용한 초경량, 에너지 절감형의 자동차 부품 소재,항공기 방열판 등에 대한 연구가 활발하게 진행되고 있다. 특히 금속 기체의 GASAR 공법은 Lotus 공법으로 Osaka 대학에서 개발되어 열교환기, 항공기, 방열기 등으로 응용이 확대되고 있다 국내에서 완제품생산은 실내장식용 복합패널로서 한소 프라임이 운영상의 문제로 생산을 중단하였으며, 유닉슨(주), 금강(주)에서 Batch식, 금성산업에서 Pot식이 일부 생산 및 연구가 진행되었으나 현재는 본연구실의 협조로 (주) 폼텍에서 발포패널을 주로 생산하고 있고 (주)드림메탈과 (주)아크로폼텍에서일부 생산되고, (주)동일알루미늄에서는 폐 scrap을 이용한 발포 Al 제조가 연구단계에 있다. 생기원에서는 분말 가열 흡음패널이 개발되었으나 강도와 내열성이 낮아 이들 특성을 향상시크는 연구가 진행중이다. 이들 제품은 성능상으로는 동양강판의 흡음패널과 KIMM의 필터용은연구개발이 낮은 수준이며, 본 연구팀과 공동 개발한 (주)폼텍의 복합패널은 10여 가지의 실용특허로 건축마감재로서 오히려 선진국수준을능가한 상태이다, 한편, 발포금속 기능성 개발은, 이들이 가지고 있는 우수한 특성 때문에 군수용으로부터 민수 산업용까지 전분야에 적용이 가능한 소재이므로 수요처를확장하고 있으므로 제품의 균질성, 안정성과 기능성 개발 향상을 위해 지속적이고 체계적인 연구가 필요하다고 생각된다.

• Journal of Life Science
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• v.18 no.9
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• pp.1239-1243
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• 2008

Though relatively little is known of the physiology involved, there is reduced kidney activity during hibernation. In this experimental study, male Korean chipmunks (Tamias sibiricus barberi) were maintained in cold conditions ($6^{\circ}C$) for 9 months, in an attempt to mimic conditions occurring during seasonal hibernation. The examination was made to determine changes of glycoconjugates on the kidney after hibernation by lectin histochemistry. The changes of lectin affinities in the kidney categorize into three groups: a) increase ones only in the early hibernation stage b) increase ones during hibernation and c) decrease ones during hibernation. The transient increase of Con A affinity in the proximal convoluted tubules were demonstrated only in the early cold-treated stage, and PNA and Con A in the distal convoluted tubules and DBA and sWGA in the collecting tubules. SBA affinity tended to increase with hibernation in the proximal convoluted tubules, but sWGA affinities were significantly decreased in the all tubule examined with hibernation. The present results suggest that the glycosylation pattern of the kidney undergoes profound changes during hibernation, and is probably associated with transiently reduced renal function.

• Journal of Korean Tunnelling and Underground Space Association
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• v.13 no.3
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• pp.277-289
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• 2011

This study proposes a new testing method for shear bearing capacity of FRP-concrete interface, which could well consider a loading condition corresponding to a tunnel lining undergoing axial compression and could be easily carried out with a simply specified specimen. A parametric study is carried out for capturing an optimized condition of coarse-sand coating of FRP, which governs shear bearing capacity of FRP-concrete interface, by using the proposed testing manner in this study. From the parametric study, it is shown that the proposed testing method is reasonably feasible in comparison with the existing testing methods. An optimum condition of coated sand size and sand density is given for the shearing capacity of FRP-concrete interface.

• Applied Chemistry for Engineering
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• v.28 no.1
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• pp.87-94
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• 2017

In this study, a catalyst based on $Pt/Al_2O_3$ supported on Mg was prepared by a wet impregnation method to investigate the $CH_4-SCR$ reaction characteristics of various alumina supports. Alumina supported on $Pt/Al_2O_3$ catalyst was converted to an $Al_2O_3$ composite, and when Mg was added, oxygen species of the active metal Pt were controlled due to electrophobic characteristics. Oxygen-controlled Pt used as a reducing agent inhibited the oxidation of $CH_4$ to $CO_2$. The addition of Mg also promoted the adsorption of NO species and the conversion of NO to $NO_2$ due to the NOx storage property on the catalyst surface.

• Korean Chemical Engineering Research
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• v.46 no.1
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• pp.124-130
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• 2008

In order to fabricate a modified poly (lactic acid) (PLA) for applications requiring high melt strength, a PLA has been irradiated in the presence of functional monomer of glycidyl methacrylate (GMA). Samples were prepared with various contents of GMA and irradiation dosages, and were characterized by observing their thermal and melt viscoelastic properties and gel faction. The complex viscosity and storage modulus of the modified PLA without GMA were lower than those of the original PLA. Those of the modified PLA decreased with increasing dosage. In the case of the modified PLA containing 0.1 phr or 0.3 phr of GMA, their changing tendency with dosage was similar to the irradiated PLA without GMA. However, the 5 kGy irradiated PLA containing 0.5 phr of GMA showed the greatly enhanced complex viscosity and storage modulus, which were about 3 and 10 times higher than those of the original PLA at a frequency of 0.1 rad/s, respectively.