Applying the basic knowledge about regulation of pigmentation towards development of strategies for cutaneous hypopigmentation |
Abdel-Malek, Zalfa A. (Department of Dermatology Cincinnati University College of Medicine Ohio, USA) |
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The photobiology of melanin pigmentation in human skin
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Rab3a and SNARE proteins : potential regulators of melanosome movement
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ScienceOn |
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An alternative approach to depigmentation by soybean extracts via inhibition of the PAR-2 pathway
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The relationship between tyrosinase activity and skin color in human foreskins
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Contribution of melanogenic proteins to the heterogeneous pigmentation of human melanocytes
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Kojic acid, a cosmetic skin whitening agent, is a slow-binding inhibitor of catecholase activity of tyrosinase
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Ultrastructural comparison of pheo- and eu-melanogenesis in animals
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Biologic Basis of Pigmentaiton
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An agouti mutation lacking the basic domain induces yellow pigmentation but not obesity in transgenic mice
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ScienceOn |
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Modulation of melanogenic protein expression during the switch from eu- to pheomelanogenesis
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Agouti signaling protein inhibits melanogenesis and the response o human melanocytes to α-melanotropin
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Arbutin : Mechanism of its depigmenting action in human melanocyte culture
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Inhibitors of mammalian melanocyte tyrosinase : In vitro comparisons of alkyl esters of gentisic acid with other putative inhibitors
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Bioactive motifs of agouti signal protein
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Novel agouti-related-protein-based melanocortin-1 receptor antagonist
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Proliferation and propagation of human melanocytes in vitro are affected by donor age and anatomical site
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Production and release of proopiomelanocortin (POMC) derived peptides by human melanocytes and keratinocytes in culture : regulation by ultraviolet B
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Keratinocytes play a role in regulating distribution patterns of recipient melanosomes in vitro
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Melanogenesis in cultured melanocytes can be substantially influenced by L-tyrosine and L-cysteine
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Eumelanin and pheomelanin contents of human epidermis and cultured melanocytes
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Human melanocortin1 receptor variants receptor function and melanocyte response to ultraviolet radiation
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Molecular structure and chromosomal mapping of the human homolog of the agouti gene
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Ex vivo study of skin phototypes
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Endothelins secreted from human keratinocytes are intrinsic mitogens for human melanocytes
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Mechanism of depigmentation by hydroquinone
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The predominant defect in dilute melanocytes is in melanosome distribution and not cell shape, supporting a role of myosin V in melanosome transport
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Induction of melanogenesis suppression : cellular pharmacology and mode differential action
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Binding capacity and activation of the MCI receptors by melanotropic hormones correlate directly with their mitogenic and melanogenic effects on human melanocytes
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The role of GSH depletion and toxicity in hydroquinone-induced development of enzyme-altered foci.
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Targeted disruption of the melanocortin-4 receptor results in obesity in mice
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Inhibition of melanosome transfer results in skin lightening
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Protease-activated receptor 2, a receptor involved in melanosome transfer, is upregulated in human skin by ultraviolet irradiation
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Mitogenic and melanogenic stimulation of normal human melanocytes by melanotropic peptides
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Combinatorial diffusion assay used to identify topically active melanocyte-stimulating hormone antagonists
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Activation of the cAMP pathway by α-melanotropin mediates the response of human melanocytes to UVB light
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Agouti protein can act independently of melanocyte-stimulating hormone to inhibit melanogenesis
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Interleukins 1α and 6 and tumor necrosis factor-α are paracrine ingibitors of human melanocyte proliferation and melanogenesis
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38 |
Photobiology of pigment cells
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39 |
Enhancement of the depigmenting effect of hydroquinone by cystamine and buthionine sulfoximine
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Basic fibroblast growth factor from human keratinocytes is a nutural mitogen for melanocytes
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Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein
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42 |
Discovery and structure-function analysis of alpha-melanocyte-stimulating hormone antagonists
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43 |
Modulation of murine melanocyte function in vitro by agouti signal protein
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44 |
Characterization of a putative α-MSH antagonist 153N-6 at melanocortin receptor subtypes by radioligand binding
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Synthesis of 153N-6 analogues and structure-function analysis at murine melanocortin-1 (MCI) receptors
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46 |
Induction of skin tanning by the subcutaneous administration of a potent synthetic melanotropin
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Mechanism of inhibition of melanogenesis by hydroquinone
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ScienceOn |