• Korean Journal of Food Science and Technology
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• v.46 no.5
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• pp.622-629
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• 2014

We studied the effects of Akebia quinata fruit extract (AQ) on acute alcohol-induced hepatotoxicity in mice. AQ (30-1,000 mg/kg body weight (BW) per day) was orally administered to the study group, once daily for 1 week. On the last day of AQ treatment, ethanol (6 mg/kg BW) was orally administered to induce acute liver injury. The AQ-treated group showed significantly lower levels of alanine aminotransferase and aspartate aminotransferase, compared to the only ethanol-treated group (ETG). The glutathione level in the AQ-treated group elevated up to 20.6%, compared to that observed in the ETG. The mRNA expression of glutathione synthetic enzymes was also higher in the AQ-treated group, compared to the ETG. The AQ-treated group also exhibited lower levels of expression of NADPH oxidase 4 and tumor necrosis factor alpha mRNA. Thus, these results show that AQ treatment can be a potential method to reduce oxidative stress and inflammation in ethanol-treated mouse liver and also that AQ can be a useful therapeutic agent for acute alcohol-induced hepatotoxicity.

• Fire Science and Engineering
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• v.26 no.4
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• pp.77-81
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• 2012

This study of aims to provide basic data for improve the performance of air respirators that generate by bad influencing elements in fire emergency field. With three types of conditions set up for these tests, the pressures of containers have been extracted; the ambient temperatures have been checked, and the generation of moisture inside and outside container have been checked and identified. Specifically, these tests have been conducted at temperatures ranging between $-20{\sim}40^{\circ}C$. The pressures of containers have been extracted to reach between 0.4~0.8 MPa, using a pressure regulating valve. These tests have resulted in no change in the temperature and moisture outside the containers and no generation of moisture inside the containers as well. Although moisture has been generated inside the pressure gauge, the amount of moisture has not exceeded 25 $mg/m^3$, i.e. the limit suggested by the Korean Government. Therefore, it is judged that the moisture generated inside air respirators, which can be the most critical issue in the equipment, is likely to be caused in the process of managing the equipment or replacing air in the equipment at places of end-users, rather than in the process of manufacturing and production of the equipment.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.4
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• pp.570-577
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• 2017

The purpose of this study was to provide a basis for the development of a health insurance payment system by exploring inpatient hospice & palliative care activities in a long-term care hospital by occupational personnel. The contents and frequency of inpatient hospice-palliative care activities were obtained retrospectively from the chart review of 12 terminally ill patients who died during the 6 months before their deaths. According to their occupational personnel, doctors were doing blood transfusion, family counseling, and medication guidance. Nurses' main activities were airway suction, oxygen supply, EKG monitoring, observing patient's status, helping medication and tube feeding. Other workers' activities are as follows: social workers were applying individualized programs, physical therapists were doing electrostimulation, nutritionists were giving nutrition evaluation and meal rounding, and careworkers were assisting with meals and nutrition. Although certain nursing activities, like emotional support, were performed by nurses, the hospice-palliative activities from doctors, social workers and physical therapists were largely unavailable for terminally ill patients in a long-term care hospital. And some terminally ill patients were receiving too intensive and invasive medical cares for end end-of-life care. The results highlight the importance of valid measures of hospice-palliative care quality and the need for establishing an adequate reimbursement system for ensuring and improving end-of-life care.

• Journal of the Korean Society of Food Science and Nutrition
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• v.33 no.5
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• pp.785-790
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• 2004

Kimchi is well known as a traditional Korean food containing various antioxidative compounds and it has been demonstrated that dietary kimchi inhibit the tissue oxidation and aging in many related studies. Ultraviolet B (UVB) radiation is the most potent among the many related factor to skin photo-aging. This experiment is designed to elucidate the inhibitory effect of solvent fractionation of various kimchi on UVB induced oxidation and erythema formation. Among solvent fractions, phenol content mostly existed in dichloromethane / ethylacetate fraction of buchu kimchi, dichloromethane fraction of Korean cabbage kimchi and ethylacetate / dichloromethane fraction of mustard leaf kimchi. Free radical scavenging activities were higher in dichloromethane and ethylacetate fraction from buchu kimchi, dichloromethane fraction from Korean cabbage kimchi, and ethylacetate fraction from mustard leaf kimchi. When the damage of photo-oxidation by UVB irradiation was tested in the presence of solvent fractions of kimchi, dichloromethane / ethylacetate fraction of buchu kimchi, ethylacetate fraction from Korean cabbage and from mustard leaf kimchi showed the higher protective activities than others. The erythema formations which were induced by UVB irradiation were decreased in solvent fractions of kimchi that hate higher antioxidant activities. In conclusion, kimchi solvent fractions having antioxidant compounds mostly inhibited photo-oxidation and erythema formation by UV-irradiation, therefore kimchi consumption can retard skin aging due to the presence of antioxidative compounds.

• Journal of the Korean Society of Food Science and Nutrition
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• v.30 no.5
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• pp.928-932
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• 2001

The protective effect of Hericium erinaceus methanol extract was investigated on benzo($\alpha$)pyrene(B($\alpha$)P) induced hepatotoxicity in mice, Hericium erinaceus extract was intraperitioneally injected once a hay for successive 5 days. followed by treatment with B($\alpha$)P on the fifth day. The elevated activities of serum aminotransferase and hepatic cytochrome P-450 by B($\alpha$)P was decreased by pretretament with Hericium erinaceus extract. Moreover, hepatic lipid peroxide content and glutathions S-transferase activity increased by B($\alpha$)P were significantly decrease, but depletion of glutathione content induced by B($\alpha$)P was prevented by Hericium erinaceus extract. In addition, the increased activities of superoxide diamutase, catalase and glutathions peroxidase after B($\alpha$)P-treatment were decreasd. Immunoblott analysis of hepatic microsomes showed that methanol extract of Hericium erinaceus suppressed protein level of the cytochrome P-450 1AI increaed by B($\alpha$)P. These results suggest that Hericium erinaceus extract may protect liver from damage induced by B($\alpha$)P.

• Journal of agriculture & life science
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• v.45 no.5
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• pp.49-56
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• 2011

This study was conducted to provide data for the maintenance of the Corylopsis coreana community within the Hallyeohaesang National Park. Survey site of Corylopsis coreana community was located at a valley, which composed of over 60% exposed rock. As this result, much of the species was damaged or washed away due to the water flow from rainfall. The tree layers dominant species were Quercus serrata and Pinus densiflora. while the subtree layers dominant species were Corylopsis coreana, Acer pseudosieboldianum, Sapium japonicum, Chamaecyparis obtusa and Cornus kousa etc. The shrub layers dominant species were Callicarpa japonica and Smilax china etc., and herbaceous layers dominant species were Disporum smilacinum etc. Increased precipitation and rainfall days were observed from May to September in this valley during 2008~2010, which likely increased soil erosion and damage. Because water flow pattern was dispersed the Corylopsis coreana seed and the soil floor was shallow, and population of Corylopsis coreana seedlings were diminished.

• Proceedings of the Korea Water Resources Association Conference
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• 2017.05a
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• pp.486-490
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• 2017

도심지에서의 침수피해는 이상홍수 및 국지성 호우 시 우수관거 시설기준 미달, 펌프장 등 배수시설이 설치되지 않아 하천의 계획홍수위보다 제내지의 지반고가 낮은 저지대 지역에서 많이 발생하고 있다. 특히, 내수침수의 경우는 외수에 따른 범람보다는 국민의 재산과 인명피해에 직접적인 영향을 미치므로 침수피해 위험도가 높은 지역의 주민에게 그 지역의 침수빈도와 범위를 인지시키고 사전대응 능력을 향상시킬 필요가 있다. 따라서 연구의 목적으로 매년 피해가 발생한 이력이 있는 위험지구에 대해 전국단위 시군구별 침수피해 지도를 작성하여 침수심 산정과 피해액 예측할 수 있는 기초자료로 활용하고, 주민들의 신속한 대처를 통해 그들의 생명과 재산을 보호하여 재난 안전 국가 이미지 제고에 기여하고자 한다. 본 연구에서는 도심지 유출모형인 XP-SWMM을 활용하여 내수재해 위험요인에 대한 전국을 해석하는 것에 한계가 있어 풍수해저감종합계획에 수록된 XP-SWMM모의 분석 결과 값을 활용하고자 하였다. 기 수립된 전국 풍수해저감종합계획의 과거 피해 자료를 바탕으로 이상 집중호우나 태풍의 내습 시 풍수해 피해 발생 가능성이 제일 높은 지역을 연구범위 대상지역으로 선정하였다. 그 중 풍수해의 주요 원인으로서 태풍, 집중호우 및 해일로 인한 피해발생 빈도가 높은 지역이면서 하천재해 및 내수침수 피해가 많은 경기도 동두천시를 연구대상 지역으로 선정하였으며, 대상지 유역 현황과 지형정보 및 빈도별 침수심을 조사하였다. 수록된 내용에 따르면 경기도 동두천시는 우수관망의 밀도가 높은 4개 위험지구를 내수재해 발생가능성 지역으로 선정하여 10년, 20년, 30년, 50년, 100년, 200년 6개 빈도에 대해 XP-SWMM 모의를 실시하였다. 이와 같이 수록된 각 빈도에 대한 모의 결과 값을 GIS기술을 이용하여 디지털화 하고 부가적인 분석을 위한 GIS데이터화 하는 내삽법을 선정하여 침수면적 및 침수심을 산출하였다. 그러나 면적비교를 통해 모의 결과 값을 디지털화 하는 과정에서 많은 오차가 발생되는 것을 확인하였고, 이를 보완하기 위해 좌표보정 자동화 프로그램을 개발하여 이러한 문제점을 제거하여 신뢰도를 향상시켰다. 이렇게 계산된 연구 대상지역의 침수심과 침수면적을 활용하여 지도제작 표준 지침서 및 가이드라인을 제시하여 한국형 호우피해 지도제작 기술개발에 기여하고, 비구조적 대책으로서 이상홍수에 대한 위험도를 파악하여 지역별 도심침수 방지를 위한 대비체계를 구축하는 등 위험지역에 대한 사전분석 및 활용에 기초자료로 도움이 되고자 한다.

• Proceedings of the SOHE Conference
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• 1999.10a
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• pp.85-101
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• 1999

새천년에 대한 미래를 생각해보면 우리에게 회망과 동시에 웬지 모를 불안올 주기도 한다. 발전지향적으로 살아 온 우리 인간의 지혜로 말미암아 현대에 살고 있는 우리는 과 거 우리 조상 어느 시대 못지 않게 첨단 과학 기술의 혜택으로 물질적 풍요와 함께 사 상적으로도 신분계급이나 남녀문제나 이데올로기의 극심한 차별이 사라져가는 그야말 로 자유스러운 생활올 맛보고 있다. 그러나 한편으로는 이러한 혜택과 이익을 얻는 대 신 지나친 물질의 생산과 사용의 과다는 우리 환경을 파괴하고 나아가 정신적으로도 물질의 지배를 받게 되는 즉, 물질의 소유와 사용에 따른 삶과 사람의 평가가 횡행하 는 기이한 구조에 우리 자신도 모르는 사이에 말려 들어가 피폐된 정신환경의 진행을 우려하지 않올 수 없다. 누구든지 공감하는 이러한 부분이 아마도 다가올 21세기에 대 한 불안이 아닐까 생각한다. 우리의 주거생활도 반세기도 채 안되는 이 시점에 그동안 놀라운 변모를 거듭하여 비교적 선진국과 가까운 수준에 육박하고 있다. 그렇다면 지금 이 시점에서 다가올 주 생활에 대한 이야기는 잘못되어지는 불안을 막고 더 멋지고 쾌적한 주거환경올 창출하 여 주거의 질을 높히기 위한 선도적 쟁점이 되어야 할 것이다. 이러한 의미에서 본고 에서는 새천년의 주거생활문화에 대한 주제를 거시적이고 개념적인 정책적 내용보다는 생활과학의 한 맥락에서 미시적이고 구체적이며 실천지향적인 뜩변에서 나아가야 할 쟁점이 무엇인지를 함께 생각해 보고자 하며 학술 이론적 내용보다는 평이한 사례를 중심으로 함께 생각해 보고자 한다. 밝혀졌다. 그러나, 생산계획시스템에서 1주 간격으로 계획오더를 이송할 때는 Order Release 방법을 적용하여 작업현장에서의 평균 리드타임과 리드타임의 변동, 공정중재고가 줄어드는 결과를 보였고, 가동률 수준이 높을수록 ORR 방법간의 차이가 크게 나타났다. 그리고 부하평준화 기능은 Order Release 정책의 유효성에 별 영향을 주지 않는 것으로 나타났다. 결론적으로, Order Release 방법은 우선순위규칙간의 성능차이를 줄이거나, 대체할 수 통제 기법이라기보다는 우선순위규칙을 보완하여 공정중재고와 작업현장에서의 리드타임, 리드타임의 편차를 줄여주는 역할을 한다고 볼 수 있다. 그리고, 계획시스템이 존재하여 계획오더가 일정기간간격으로 이송되는 환경에서 특히 유용하다는 결론을 얻었다. 알 수 있었다. 것인데, 제조업에서의 심각한 고비용, 저효율 문제 를 해결하기 위해 필수적으로 도입해야만 하는 실정이다. 또한 소비자의 다양한 요구로 인 하여 제품의 종류와 사양면에서 심한 변동을 보이는 시장 수요에, 신속한 정보처리로 대응 하는데도 크게 기여하고 있다. 이에 본 연구에서는, 자동차 Job Shop의 동기화 생산방식을 지원하는 동기화 생산시스템의 구축 모델을 제시하고자 한다.과로 여겨지며, 또한 혈청중의 ALT, ALP 및 LDH활성을 유의성있게 감소시키므로서 감잎 phenolic compounds가 에탄올에 의한 간세포 손상에 대한 해독 및 보호작용이 있는 것으로 사료된다.반적으로 홍삼 제조시 내공의 발생은 제조공정에서 나타나는 경우가 많으며, 내백의 경

• Journal of the Society of Cosmetic Scientists of Korea
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• v.47 no.3
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• pp.237-245
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• 2021

Particulate matter and ultra-particle matters generally refer to very small floating dust, such as 1/6 to 1/7 and 1/20 to 1/30, respectively, compared to the thickness of human hair, and contain various types of heavy metal ions. In addition to breathing, particle matters (PM) that flows in through the gaps in the pores of the skin can induce health problems in the body's tissues and skin, so it must be removed by blocking the inflow or by washing. Through this study, we confirmed the possibility that heavy metal ions can be adsorbed and removed by using Oryza sativa (Rice) bran oil (OSBO). In addition, the cell viability is much higher than that of grain-derived components through cytotoxicity experiments, and the cytoprotective effect of an external stimulus source can be expected. It was confirmed that the expression amount of COL1A1 mRNA increased, and accordingly, it was believed that wrinkles that might be caused by moisture lost by heavy metal ions in fine dust could be alleviated. Based on the results of these experiments, we tried to present a cosmetics containing OSBO, which is a wash-off formulation, in order to finally remove heavy metals.

• Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
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• v.9 no.6
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• pp.711-718
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• 2019

Spectrum analyzer and electromagnetic field meter were used to investigate the EM generation behaviour in different types of home electrical appliances. During microwave oven operation, the EM power measured at a point 30cm apart was measured in the range of 8~11mW/㎡, the strength of the low frequency magnetic field was 60~80mG and the electric field strength was measured at 150~160V/m. For smart phone wireless charging pad, it was measured at an electromagnetic power of 0.4mW/㎡, an electric field of 160 V/m and a magnetic field of 1mG at a point 10cm away. For microwave oven and wireless charging pad, if used within 10cm, the size of the electric field has been measured at a large value that exceeds the human body protection standard and may be hazardous to humans. On the other hand, home appliances such as TVs, hairdryers and refrigerators all showed very low levels of electromagnetic waves, electric fields and magnetic fields, with no harmful effects seen. For electromagnetic shielding, the metal Cu fabric and metal foil had a high level of EM shielding, while polymer films had a low EM shielding characteristic.