• Title/Summary/Keyword: 보간탕(補肝湯)

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Two Cases of Diabetic Peripheral Polyneuropathy Improved by Bogan-tang. (보간탕으로 호전된 당뇨병성 말초신경병증 2례)

  • 권영구;최기림;이진신;이병철;안영민;안세영;두호경
    • The Journal of Korean Medicine
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    • v.23 no.1
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    • pp.170-176
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    • 2002
  • Diabetic Peripheral Polyneuropathy is one of the most distressing complications of diabetes, Drugs such as narcotic analgesics, tricyclic antidepressants, anticonvulsants and phenothiazines have been used to treat diabetic peripheral polyneuropathy, but these drugs are not very effective for the many patients and the side effects may become intolerable. In oriental medicine, usually the main etiology of diabetic Peripheral Polyneuropathy is insufficiency of Blood due to the state of dry-heat in the human body. Therefore, we use Bogan-tang to treat numbness of Diabetic Peripheral Polyneuropathy. Bogan-tang was administrated twice a day for 15 days, and VAS Scale was performed every day to evaluate numbness and insufficiency of blood. In both cases, numbness and insufficiency of blood were improved without any side effects. This study suggests that Bogan-tang is an effective drug in the treatment of Diabetic Peripheral Polyneuropathy.

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Hyeongok's Bogan-tang was Combined according to the Theory for Properties and Tastes of Herbal Medicines (현곡(玄谷) 보간탕(補肝湯)의 구성한약과 그 기미배오(氣味配伍) 분석)

  • Shin, Soon-Shik
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.21 no.3
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    • pp.591-595
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    • 2007
  • There are eight kinds of formulas for invigorating the liver to cure its asthenic syndrome based on the types of preparation formulas Began-tang, Boganhwan, Bogansan, Bogandan, Boganeum, Boganjoo, Boganjeon and Bogango. Another formula called Bocheonghwan is to invigorate the green colour of liver. There are 22 kinds of Bogan-tang, 12 kinds of Boganhwan, 25 kinds of Bogansan, one kind of Bogandan, one kind of Boganeum, one kind of Boganjoo, one kind of Boganjeon, one kind of Bogango, and two kinds of Bocheonghwan. Combination of herbal medicines, carried out in formulas for invigorating the liver, consists of various kinds depending on medical scientists' personal experience in medical treatment without any general principles, which makes it difficult to apply it to clinical use. The objectives of this study lie in theoretical establishment of Bogan-tang for curing the asthenic syndrome of liver through analyzing the component medicines and combination principles of Hyeongok's Bogan-tang, and furthermore, maximizing the clinical use of Began-tang. This study analyzed the component medicines and combination principles of Hyeongok's Bogan-tang based on the theory for properties and tastes of herbal medicines from the ${\ulcorner}$yellow Emperor's Canon of Internal Medicine${\lrcorner}$ , the theory for principal herbal medicine, assistant herbal medicine, adjuvant herbal medicine, dispatcher herbal medicine, and the five elements doctrine. Hyeongok's Began-tang is an odd prescription, composed of 7 kinds of ingredients No.1 Radix Angelicas Sinensis (2don;7.5g), No.2 Rhizoma Chuanxiong (1don;3.75g), No.3 Radii Polygoni Multiflori (1don), No.4 Fructus Lycii (1don), No.5 Cortex Cinnamomi (1don), No.6 Rhizoma Gastrodiae (1don), and No.7 Radix Glycyrrhizae (1don). There are three methods for curing the asthenic syndrome of liver according to the five elements doctrine invigorating the liver, invigorating the kidney and purging the lung. First, if you suffer from the asthenic syndrome of the liver, you need to invigorate your liver. There are two available methods, including taste and property invigoration according to the theory for properties and tastes of herbal medicines. They each imply the pungent taste and the warm property invigorate the liver. In the case of taste invigoration, two herbal medicines with pungent taste, Radix Angelicas Sinensis and Rhizoma Chuanxiong, are combined into the principal and assistant herbal medicine, respectively. For property invigoration, two herDal medicines with the warm property, Cortex Cinnamomi and Rhizoma Gastrodiae, are combined into adjuvant herbal medicines. Secondly, if you suffer from the asthenic syndrome of the liver, you need to invigorate your kidney which is mother in the mother-child relationship in inter-promotion among the five elements. There are two methods to invigorate the kidney, including taste and property invigoration according to the theory for properties and tastes of herbal medicines. They each mean the bitter taste and the cold property invigorate the kidney. Therefore, it is important to use bitter herbal medicines for taste invigoration and cold ones for property invigoration. Both Differ and cold herbal medicines, Radix Polygoni Multiflori and Fructus Lycii, are combined into adjuvant herbal medicines. Lastly, if you suffer from the asthenic syndrome of the liver, you need to purge your lung which is an element being surpassed in the relationship between the elements surpassed and ones not surpassed in inter-restraint among the five elements. There are two methods to purge the lung, which include taste and property invigoration according to the theory for properties and tastes of herbal medicines. Taste invigoration means to purge the lung with pungent taste and property invigoration to purge the lung with warm property. Therefore, it is important to use pungent herbal medicines for taste invigoration and warm ones for property invigoration. Both pungent and warm herbal medicines, Radix Angelicas Sinensis and Rhizoma Chuanxiong, were combined to invigorate and purge the lung. In addition, Radix Glycyrrhizae are combined as dispatcher herbal medicine, harmonizing all the herbal medicines composing the formula. First, to cure the asthenic syndrome of the liver, the methods of invigorating the liver and the kidney, and purging the lung should be used according to the five elements doctrine. Secondly, herbal medicines appropriate for those treatment methods should be chosen according to the theory for properties and tastes of herDal medicine and thirdly, the combination of those herbal medicines should be carried out according to the theory for principal herbal medicine, assistant herbal medicine, adjuvant herbal medicine, dispatcher herbal medicine. As a good example, Hyeongok's Bogan-tangon is combined according to the above theories. In conclusion, this formula was created by applying to the theory for properties and tastes of herbal medicines.

"상한잡병론"에 나타나는 양허증후의 변증론치에 대한 고찰

  • Do, Han-Hwa
    • Journal of Korean Medical classics
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    • v.19 no.1 s.32
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    • pp.207-210
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    • 2006
  • ${\ulcorner}$상한잡병론(傷寒雜病論)${\lrcorner}$에 나오는 양허증의 병인병리(病因病理)에 대한 내용을 종합하여 검토하고, 그 처방의 구성 약물과 용약 규율에 대하여 살펴본 결과, 양허증을 치료하는 상용약물로는 부자 계지 건강 오수유 생강 등이 쓰였음을 알 수 있었다. 임상에서 약을 사용할 때에는 장부의 생리적 특징에 근거하여 약물을 배합하여야 좋은 효과를 얻을 수 있다. 예를 들어 심양허(心陽虛)에는 계지감초(桂枝甘草)에 복령(茯笭)을 배합하고, 신양허(腎陽虛)에는 진무탕(眞武湯) 신기환 등(等)에 복령(茯笭), 택사(澤瀉), 백출(白朮) 등의 약물을 배합하여, 비양허(脾陽虛)로 인한 담음(痰飮)에는 계지감초(桂枝甘草)의 신감(辛甘)한 약성으로 화양(化陽)하고, 복령(茯笭), 백출(白朮)로 건비리습(健脾利濕)하는 영계출감탕을 사용하며, 심하(心下)에 수(水)가 정체된 경우에는 윗 처방에 사인 백두구 등의 온건비위(溫健脾胃)하고 성비소식(醒脾消食)하는 약물을 가하여 사용한다. 폐양허(肺陽虛)하여 폐위가 된 경우에는 감초(甘草) 건강(乾姜) 등을 사용하여 온폐복기하는데, 이는 ‘배토생금(培土生金)’의 의미이다. 간양허(肝陽虛)가 나타나는 경우는 매우 드문데, 위기가 허한(虛寒)하여 간(肝)이 소설(疏泄)작용을 못할 때에는, 오수유(吳茱萸)로 온위산한(溫胃散寒)하고, 인삼(人參) 대조(大棗)로 보중익기하며, 오수유(吳茱萸) 생강(生姜)의 신산(辛散)작용으로 간기를 다스리는 오수유탕(吳茱萸湯)을 사용하여 강역지구(降逆止嘔)하며, 혼(魂)을 수렴하지 못하여 생긴 실안(失眼)에는 산조인탕(酸棗仁湯)으로 보간(補肝)하여 치료하며, 간경(肝經)에 한사(寒邪)가 침입하여 근맥이 연급(攣急)하게 된 경우에는 지주산(蜘蛛散)을 사용하여 온경산한(溫經散寒)한다.

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Protective Effects of Iljungbogan-Tang on Acute Hepatotoxicity Induced by $CCL_4$ and Acetaminophen (급성 간독성에 대한 일중보간탕(一中補肝湯)의 해독 효과에 관한 연구)

  • Kim, Joon-Myoung;Park, Yang-Chun;Son, Gi-Jung
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.20 no.2
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    • pp.410-413
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    • 2006
  • This study was done to investigate the protective effects of Iljungbogan-Tang on acute hepatotoxicity of rats induced by $CCL_4$ and acetaminophen. The subject animals were divided into 3 groups : control group(administrated 0.5% carboxymethyl cellulose), sample group(30, 100, 300, 600mg/kg administrated), positive control group (administrated silymarine), Acute hepatotoxicity of rats were induced by $CCL_4$ and acetaminophen, and the serum transaminase(AST, ALT) were measured for enzyme activities. The inhibitory effects on the serum AST activities were noted in sample group(100, 300, 600mg/kg administrated) on hepatotoxicity of rats induced by $CCL_4$. The inhibitory effects on the serum AST, ALT activities were noted in sample group(30mg/kg administrated) on hepatotoxicity of rats induced by acetaminophen. The inhibitory effects on the serum AST activities were noted in sample group(600mg/kg single dose administrated) on hepatotoxicity of rats induced by acetaminophen. It is considered that Iljungbogan-Tang has protective effects against hepatotoxicity in rats induced by $CCL_4$ and acetaminophen. So it is required to study about the actions of mutual relation of medicines and patho-mechanism through experiment.

A Comparative Study on the Etfects of 『Palmisoyo-San gamibang』, 『Gyebu-Tang』 and 『Boganyangje』 on the Thyrotoxicosis of Rats (갑상선중독유발 흰쥐에 미치는 팔미소요산가미방(八味消遙散加味方)과 계부탕(桂附湯)및 보간양제(補肝陽劑)의 영향 비교 연구)

  • Lee, Yeun-Seong;Soh, Kyeong-Sun;Jeong, Chan-Gil
    • Journal of Pharmacopuncture
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    • v.8 no.3
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    • pp.39-50
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    • 2005
  • In order to study comparatively the effects of "Palmisoyo-San gamibang(八味消遙散加味方)"(AP), "Gyebu-Tang(桂附湯)"(GT) and "Boganyangje(補肝陽劑)" (BG) on the thyrotoxicosis rats, we have made thyrotoxicosis rat model by administration sodium levothyroxine p.o. during 4 days(Control group), and have administered solid extract of AP(236.8mg/200g/day : Sample I group), GT(80mg/200g/day : Sample II group) and BG(70.4mg/200g/day : Sample III group) p.o. to thyrotoxicosis rats during 3 days from 3rd day. We measured the body weight(BW), body temperature(BT), levels of Serum $T_3{\cdot}T_4{\cdot}free\;T_3{\cdot}free\;T_4$ and TSH after administrating solid extract of AP, GT and BG. The results are summarized as follows: 1. Sample I group showed significantly high increasing rate compared with Control, Sample II and Sample III group, but it showed significantly lower levels of BT, $T_4$ and free $T_4$ than those of Control, Sample II and Sample III. group. 2. We could know that AP suppress the alteration of $T_4$ to $T_3$. 3. Sample II and Sample III group showed opposite results to Sample I group in the BW., BT, $T_4$ and free $T_4$ Especially Sample III was significantly higher than Control, Sample I and Sample II, so we could guess that BG stimulates the formation of thyroid hormones. According to the above experimental results, "Palmisoyo-San\;gamibang(八味消遙散加味方)" is assumed to have a curative effect against the thyrotoxicosis rat induced by sodium levothyroxine, and to suppress the alteration of $T_4$ to $T_3$. And we can suppose that "Boganyangje(補肝陽劑)" has a curative effect against the hypothyroidism.