• Korean Journal of Animal Reproduction
• /
• v.24 no.2
• /
• pp.125-142
• /
• 2000

13). Analysis of a purified preparation of eCG revealed that its $\beta$ -subunit consists of 149 amino acids, which was confirmed by the molecular cloning of its cDNA. There seem to be at least four to six, or even as many as 11, O-glycosylation sites on the extended C-tenninal region of the eCG $\beta$-subunit. Interestingly, eCG is a unique member of this family, as it appear to be a single molecule that possesses both LH- and FSH-like activities. Using the cDNA prepared from mRNA extracted from equine placental and pituitary tissues, we cloned the cDNA of eCG $\alpha$- and $\beta$ -subunits and eFSH $\beta$ -subunit. The mRNA expression of each subunit seems to be independently regulated, which may account for differences in the quantities of $\alpha$ - and $\beta$ -subunits in the placenta and pituitary. Thus, eCG is a distinct molecule from the view points of its biological function and glycoresidue structures. Recombinant eCGs including the mutants which lack oligosaccharides will be useful tools for analyzing the structure-function relationships of gonadotropins in the horse as well as other species. Similar experiments will also clarify the proposed structure and biological functions for the glycoprotein hormones. These experimental are now possible, and hopefully a resolution of the existing controversy will be forthcoming in the near future.

• Journal of Radiation Protection and Research
• /
• v.26 no.4
• /
• pp.393-398
• /
• 2001

The non-combustible RI wastes disposed of in hospital every year emit ${\gamma}$-ray or ${\beta}$-ray but their activities are very low to the extent of background. Development of more simple methods is needed because the conventional detection methods are so ineffective and complex. In this study, to solve this problem, detection method using efficiency curve for ${\gamma}$-ray emitting radioactive wastes measurement is proposed and experimental detection efficiency equation is also determined through HPGe's standard specimen measurement. For ${\beta}$-emitting radioisotopes detection, new measurement method using detection efficiency estimated by Monte Carlo simulation and SBD measurements is also proposed. According to the results of this paper, the unknown activity of low-level radioactive wastes without LSC requiring the preparation of standard sample and measurement for standard source detection efficiency could be determined efficiently and simply about ${\pm}17%$ in errors by using the theoretical detection efficiency and the SBD measurement result.

• The Journal of Korea Institute of Information, Electronics, and Communication Technology
• /
• v.13 no.5
• /
• pp.403-411
• /
• 2020

Since the analog circuit of the beta ray sensor circuit for the true random number generator and the power and ground line used in the comparator circuit are shared with each other, the power generated by the digital switching of the comparator circuit and the voltage drop at the ground line was the cause of the decreasein the output signal voltage drop at the analog circuit including CSA (Charge Sensitive Amplifier). Therefore, in this paper, the output signal voltage of the analog circuit including the CSAcircuit is reduced by separating the power and ground line used in the comparator circuit, which is the source of digital switching noise, from the power and ground line of the analog circuit. In addition, in the voltage-to-voltage converter circuit that converts VREF (=1.195V) voltage to VREF_VCOM and VREF_VTHR voltage, there was a problem that the VREF_VCOM and VREF_VTHR voltages decrease because the driving current flowing through each current mirror varies due to channel length modulation effect at a high voltage VDD of 5.5V when the drain voltage of the PMOS current mirror is different when driving the IREF through the PMOS current mirror. Therefore, in this paper, since the PMOS diode is added to the PMOS current mirror of the voltage-to-voltage converter circuit, the voltages of VREF_VCOM and VREF_VTHR do not go down at a high voltage of 5.5V.

• Journal of the Institute of Electronics and Information Engineers
• /
• v.53 no.11
• /
• pp.99-106
• /
• 2016

When radon is staying at alveoli and bronchial tubes, the collapse of radon creates progeny nuclides (alpha ray, beta ray, gamma ray, etc.). They emit radiation causing a mutation in the chromosome of the cell, resulting in lung cancer. In other words, the main cause of lung cancer is radiation emitting as the result of radon collapse rather than radon gas. The 82% of radiation exposed to people is the natural radiation. Most of the natural radiation is radon. If we properly control the concentration of radon indoors, the probability of occurrence of lung cancer could be decreases to be 70%. Until now, to measure the indoor radon concentration, imported radon sensors are needed. So, DB construction of indoor radon emission and popular radon measuring apparatus should be developed. In this paper, we propose the radon detecting method using PIN photodiode. Also, we confirmed the PIN photodiode could be used as radon sensor module through some experimental studies.

• Proceedings of the Korean Vacuum Society Conference
• /
• 2013.02a
• /
• pp.232-233
• /
• 2013

본 발표에서 2012년 나노융합산업원천기술개발사업 꼭지로 연구개발을 수행하고 있는 "외부 충전없이 반영구적으로 사용이 가능한 10 mWh/cm2급 동위원소기반 전고상(全固相) 하이브리드 전지 원천기술 개발" 사업의 핵심내용을 간략히 소개하고자 한다. 본 과제의 핵심내용은 국내 유일의 원자로인 하나로의 중성자 빔라인을 이용하여 ${\beta}$-선을 방출하는 동위원소파우더를 생산하고, 방출되는 ${\beta}$-선을 효율적으로 흡수할 수 있는 PN-접합 전지구조에 노출시켜 2차적인 e-h 쌍을 생성시키고, 분리시키고 전극으로 포집하여 전력을 생산하는 한국형 동위원소전지 개발에 있다. 더하여 실시간으로 생성되는 미세한 출력전력을 증폭시켜 저장할 수 있는 고효율 전고상 이차전지와 전력제어회로를 포함하는 한국형 하이브리드전지관련 원천기술 개발관련 세부 사업내용을 소개함으로 관련분야 연구에 대한 국내관심을 환기시켜 관련기술개발을 촉진하고자 한다.

• Journal of Ocean Engineering and Technology
• /
• v.28 no.5
• /
• pp.371-377
• /
• 2014

In this study, the hydrodynamic characteristics of various types of jack-up legs for a wind turbine installation vessel were analyzed. Using the modified Morison equation, the wave and current excitation forces on the jack-up legs were calculated. A modal analysis was performed to predict the dynamic responses for various types of jack-up legs. The Newmark-beta time integration scheme was used to solve the equation of motion in waves in the time domain. The maximum displacement and maximum bending stress were computed for four different types of legs, and their results were compared to select an optimum leg type. Finally, a six-leg jack-up rig with the selected optimal legs was modeled, and its natural period and hydrodynamic behaviors were evaluated.

• Analytical Science and Technology
• /
• v.5 no.4
• /
• pp.381-387
• /
• 1992

Optimum counting condition of a low level liquid scintillation counter for radiocarbon dating has been determined to minimize the contribution of tritium activity and get the highest FOM by the variation of scintillation solutions, scintillation solution to benzene ratio, and ${\beta}$-ray spectrum counting ranges. Under the condition, background count rate has been reduced to $2.26{\pm}0.03cpm$, and the maximum measurable age reached to about 40,000 years. And the practicality of counting system has been verified by the analysis of shell and peat samples.

• Journal of Radiation Protection and Research
• /
• v.24 no.3
• /
• pp.171-184
• /
• 1999

In this paper, using statistical theory the basic concepts and the formulars of lower limit of detection were deasribed. Assuming that risks of 5% are acceptable (95% confidence level), lower limits of detection were calculated on the measuring apparatus for alpha, beta and gamma nuclides. Also, on the basis concepts of lower limit of detection, the MDA values were calculated for the radionuclides detected easily in the environment. These results make it possible to evaluate confidence limits on the radioanalytical results in the environmental sample.

• The Transactions of The Korean Institute of Electrical Engineers
• /
• v.61 no.11
• /
• pp.1706-1712
• /
• 2012

The Beta-ray absorption method (BAM) gives a good solution for measuring the mass concentration of atmospheric particles(PM10 and PM2.5). To determine particular matters (PM) concentration, a ratio of the number of detected beta-ray intensity passing through the clean filter and the dust-sampled filter is used. These intensity data measured in air pollution monitoring such as PM10 and PM2.5 usually contained the additive noise(thermal noise, power supply noise and etc.). Therefore, the estimation performance of mass concentration can be deteriorated by these noises. In this paper, we present a new noise reduction method that is essentially required to develope an automatic continuous PM monitoring system using beta-ray absorption method. By combining the block data averaging technique and curve fitting, in the proposed method, the additive noise can be reduced in the measured data. To evaluate the performance of the proposed method, computer simulations were performed with computer generated signals as the input.

• Nuclear Engineering and Technology
• /
• v.27 no.4
• /
• pp.635-643
• /
• 1995

핵의학(nuclear medicine )이 란 방사성 및 안정 핵종의 동위원소표지 화합물을 인체에 투여하여, 관심장기의 형태 및 기능을 평가하여 해부학적 또는 생리학적 상태를 진단, 치료하는 의학의 전문 분야이다. 핵의학에 이용되던 방사성 핵종은 1960년대 까지만 해도 $^{131}$ I이 주였으나 1970년대 부터는 $^{99}$Mo -$^{99m}$ Tc 발생기와 $^{99m}$ TC으로 표지된 방사성의 약품이 활발히 이용되면서 $^{131}$ I을 대신하게 되었다. 원자로-생산핵종들의 특성은 중성자가 과잉이어 붕괴시 배타입자를 방출하는 점으로, 이것이 각종 질병의 치료에 이용되고 있다. 특히 각종 표시 화합물의 성질을 이용하여 원하는 부위에 방사선을 집중시킬 수 있음이 외부조사보다 유리한 점이다. 방사성핵종을 이용한 악성종양의 치료에 가장 성공적인 것은 분화된 갑상선 암환자에서 $^{131}$ I을 사용한 것이며, 갈색세포종 등에 $^{131}$ I-MIBG도 효과적이다. 악성종양의 골전이 치료에 베타선을 방출하는$^{32}$P, $^{186}$ Re, $^{153}$ Sm 등이 이용되었다. 종양의 동맥에 주입하여 세동맥이나 모세혈관에 걸리는 기름, 교진 또는 입자에 의한 치료에 $^{131}$ I-lipiodol, ethiodol, $^{32}$P 또는$^{90}$ Y흡사 ceramic resin 미소구 $^{166}$ Ho 유산중합체 미소구 등이 이용된다. $^{166}$ Ho, $^{198}$ Au, $^{32}$P, $^{90}$ Y, $^{169}$ Er, $^{186}$ Rc, $^{131}$ I, $^{211}$ At 등 의 방사성 핵종의 교질, 미소구 또는 단세포군 항체표지 형태로 직접 종양내 또는 공동이나 체강에 투여하는 치료법이 있다. 류마치스 관절염의 슬관절에 $^{165}$ Dy colloid를 주사하는 $^{166}$ Ho-MAA도 활발히 이용되고 있다.