• Journal of Radiation Protection and Research
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• v.40 no.4
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• pp.277-282
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• 2015

This study was to investigate the effects of the hot compress pack on alleviating local muscular discomfort, stiffness in limbs as well as the chronic pains such as migraine in terms of hemodynamics. In this study, the hot compress band was put on the neck and the local physiological change on the stimulation site and the cranial blood circulation change were examined. We recruited healthy volunteers (n=8, mean age: 32.13 (4.61)), who participated in the magnetic resonance imaging (MRI) study. Local skin color and temperature were measured for the local effect of the hot compress band and the changes of intra-cranial and extra-cranial blood vessels were examined with MR angiography (MRA) images. The skin temperature increased from $36.4^{\circ}C$ at the rest condition to $36.7^{\circ}C$ and $37.1^{\circ}C$ after 15 min and 30 min stimulation, respectively. The change of the extra-cranial blood vessels between pre-stimulation and post-stimulation of 30 min was significantly increased (+38.8%), while the change of the intra-cranial blood vessels was negligible. In this study, we demonstrated that the hot compress band on the neck yielded the increase of local skin temperature on the stimulation site and it made an effect on the extracranial circulation. In conclusion, the stimulation with a hot compress could facilitate the blood circulation, causing to relieve the muscular discomfort, stiffness in limbs as well as the chronic pains such as migraine.

• Journal of Radiation Protection and Research
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• v.36 no.3
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• pp.134-139
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• 2011

In this research, we developed the newly cloud chamber apparatus by using Peltier device to apply nuclear physics experiment in high school or university. We observed the cosmic rays track by using the developed apparatus and a camcorder. And we compared and analyzed the acquired data. From the results, we acquired the following conclusions and suggestions : First, it is very difficult to observe the cosmic rays track in the typical cloud chamber because of the low frequency of it. But in the newly developed cloud chamber we can observe easily the cosmic rays track owing to the high frequency of it. Second, when we do the experiment with the newly developed apparatus, we found that the cosmic rays track happens well under the condition that the temperature of the upper place of cooling plate must be below 5$^{\circ}C$ with more than isopropanol $1.04{\times}10^{-5}$ $ml{\cdot}mm^{-3}$. Third, the newly developed apparatus will be improved to have better precision by controling the temperature of cooling plate in the cloud chamber by current intensity. Therefore we think that it is very useful to use the newly developed apparatus in the nuclear physics experiment in highschool or university.

• Journal of Radiation Protection and Research
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• v.36 no.3
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• pp.168-173
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• 2011

This study investigated characteristics of dose distribution at junction field of X-ray and electron beams according to the method for fabricating the insert block on the electron cone. Insert block were fabricated to the divergency cutout block and the straight cutout block. For the 6 MV X-ray and 10 MeV nominal energy of electron beam, we was adjacent to the light field of X-ray and electron beam at a surface of matrix chamber and measured to beam profile of abutted field in the 0, 1, 2, 3 cm measurement depth. As a result, characteristics of dose distribution at junction field, straight block was existent that over dose area exceed the give dose more than 5% and under dose area with a rapid change in dose distribution. However, divergency block had remarkably decreased the over dose area caused by the lateral scattering effects of decrease, and being existed uniformity dose distribution in the junction field. Therefore, divergency block were the benefits of radiation dose delivery, in order to applied the clinical, measurement of electron beams according to the fabrication method of the block should be considered carefully.

• Journal of Radiation Protection and Research
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• v.36 no.3
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• pp.160-167
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• 2011

This study conducts cross-comparison through verification of treatment planning of using beam spoiler and bolus, according to the dose variation of different tumor bed and metastatic lymph node cancers, against ionization and optically stimulated luminescence detectors(OSLDs), in head and neck radiotherapy. Verification of treatment planning examined the feasibility of inserting detectors through simulated solid dry water slabs under identical irradiated conditions from treatment planning system to measure beam spoiler and 0.5, 1 cm bolus. In addition, two detectors were cross-compared for verification of treatment planning accuracy and reliability within ${\pm}$2%. The study found that, given a beam spoiler thickness of 0.5 cm and beam spoiler-to-skin distance of 10 cm subjected to optimal dose distribution given for metastatic lymph node cancers, the bolus low-level skin dose was less, and the tumor bed dose reduced slightly. Additionally, two detectors were cross-compared for accuracy within ${\pm}$1%. Accordingly, The use of beam spoiler was determined that reduces skin side effects and can deliver an optimal dose distribution for tumor, and to apply to future clinical studies should be performed.

• Journal of Life Science
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• v.26 no.2
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• pp.265-274
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• 2016

Toxin-antitoxin (TA) systems are ubiquitous genetic modules that are evolutionally conserved in bacteria and archaea. TA systems composed of an intracellular toxin and its antidote (antitoxin) are currently classified into five types. Commonly, activation of toxins under stress conditions inhibits diverse cellular processes and consequently induces cell death or reversible growth inhibition. These effects of toxins play various physiological roles in such as regulation of gene expression, growth control (stress response), programmed cell arrest, persister cells, programmed cell death, phage protection, stabilization of mobile genetic elements or postsegregational killing of plasmid-free cells. Accordingly, bacterial TA systems are commonly considered as stress-responsive genetic modules. However, molecule screening for activation of toxin in TA system is available as development of antimicrobial agents. In addition, cytotoxic effect induced by toxin is used as effective cloning method with antitoxic effect of antitoxin; consequently cells containing cloning vector inserted a target gene can survive and false-positive transformants are removed. Also, TA system is applicable to efficient single protein production in biotechnology industry because toxins that are site-specific ribonuclease inhibit protein synthesis except for target protein. Furthermore, some TA systems that induce apoptosis in eukaryotic cells such as cancer cells or virus-infected cells would have a wide range of applications in eukaryotes, and it will lead to new ways of treating human disease. In this review, we summarize the current knowledge on bacterial TA systems and their applications.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.10
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• pp.403-411
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• 2016

Recently, the number of occurrences of inundation and the severity of flood damage has increased rapidly as the frequency of localized heavy rainfall and the ratio of impervious area increased in urban areas. Most local governments focus on employing structural measures (e.g., the construction of detention reservoirs/pump stations, rehabilitation of drainage and sewer pipes) to prevent urban inundation. On the other hand, the effectiveness of implementing such structural measures is being dimished because there are already many inundation prevention facilities. The limitation of structural measures can be overcoming by employing non-structure measures, such as flood alerts and the operation of drainage facilities. This study suggests the pump operation rule (i.e., suggesting pump stop level) for a new detention reservoir operating method, which triggers the operation of a pump based on the water level at the monitoring node in urban drainage system. In the new reservoir operation, a total of 48 rainfall events are generated by the Huff distribution for determining the proper pump stop level. First, the generated rainfall events are distributed as frequencies, quartiles, and durations. The averaged system resilience value was determined to range from 1.2 m to 1.5 m is based on the rainfall-runoff simulation with rainfall generated by the Huff distribution. In this range, 1.2 m was identified considering the safety factor of 1.25 by the Standard on sewer facilities in 2011.

• Journal of the Institute of Electronics and Information Engineers
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• v.53 no.2
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• pp.76-86
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• 2016

SQL Injection attacks are the most widely used and also they are considered one of the oldest traditional hacking techniques. SQL Injection attacks are getting quite complicated and they perform a high portion among web hacking. The big data environments in the future will be widely used resulting in many devices and sensors will be connected to the internet and the amount of data that flows among devices will be highly increased. The scale of damage caused by SQL Injection attacks would be even greater in the future. Besides, creating security solutions against SQL Injection attacks are high costs and time-consuming. In order to prevent SQL Injection attacks, we have to operate quickly and accurately according to this data analysis techniques. We utilized data analytics and machine learning techniques to defend against SQL Injection attacks and analyzed the execution plan of the SQL command input if there are abnormal patterns through checking the web log files. Herein, we propose a way to distinguish between normal and abnormal SQL commands. We have analyzed the value entered by the user in real time using the automated SQL Injection attacks tools. We have proved that it is possible to ensure an effective defense through analyzing the execution plan of the SQL command.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.12 no.4
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• pp.724-729
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• 2008

In the case of 'MAEMI', the Typhoon which formed in September, 2003, the largest-scale damage of tidal wave was caused by the co-occurrence of Typhoon surge and full tide. Until now Korea has been focusing on the calculating the amount of damage and its restoration to cope with these sea and harbor disasters. It is essential to establish some systematic counterplans to diminish such damages of large-scale tidal invasion on coastal lowlands considering the recent weather conditions of growing scale of typhoons. Therefore, the purpose of this research is to make the counterplans for prevention against disasters fulfilled effectively based on the data conducted by comparing and analyzing the accuracy between observation values and the results of estimating the greatest overflow area according to abnormal tidal levels centered on Masan area where there was the severest damage from tidal wave at that time. It's necessary utilize data like high-resolution satellite image and LiDAR(etc.) for correct analysis data considering geographical characteristics of dangerous area from the storm surge. And we must make a solution to minimize the damage by making data of dangerous section of flood into GIS Database using those data (as stated above) and drawing correcter damage function.

• Korean Journal of Environmental Biology
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• v.37 no.1
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• pp.72-81
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• 2019

Bisphenol A (BPA), a representative endocrine disrupting chemicals, has adverse effects on growth, development and reproduction in aquatic organisms. The object of this study was to investigate the modulation of antioxidant enzyme-coding genes using quantitative real time RT-PCR (qRT-PCR), enzyme activity and total protein content, to understand oxidative stress responses after exposure to BPA for 48 h in brackish water flea Diaphanosoma celebensis. The BPA ($3mg\;L^{-1}$) significantly upregulated the expression of Cu/Zn-SOD, Mn-SOD, and catalase (CAT) mRNA. Three GST isoforms (GST-kappa, GST-mu, and GST-theta) mRNA levels significantly increased at the rate of $0.12mg\;L^{-1}$ of BPA. In particular, GST-mu showed the highest expression level, indicating its key role in antioxidant response to BPA. SOD activity was induced with a concentration-dependent manner, and total protein contents was reduced. These findings indicate that BPA can induce oxidative stress in this species, and these antioxidants may be involved in cellular protection against BPA exposure. This study will provide a better understanding of molecular mode of action of BPA toxicity in aquatic organisms.

• Journal of Korea Water Resources Association
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• v.54 no.10
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• pp.747-757
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• 2021

Quantification of extreme rainfall is very important in establishing a flood protection plan, and a general measure of extreme rainfall is expressed as an T-year return level. In this study, a method was proposed for quantifying spatial distribution and uncertainty of daily rainfall depths with various return periods using a hierarchical Bayesian model combined with climate and geographical information, and was applied to the Seoul-Incheon-Gyeonggi region. The annual maximum daily rainfall depth of six automated synoptic observing system weather stations of the Korea Meteorological Administration in the study area was fitted to the generalized extreme value distribution. The applicability and reliability of the proposed method were investigated by comparing daily rainfall quantiles for various return levels derived from the at-site frequency analysis and the regional frequency analysis based on the index flood method. The uncertainty of the regional frequency analysis based on the index flood method was found to be the greatest at all stations and all return levels, and it was confirmed that the reliability of the regional frequency analysis based on the hierarchical Bayesian model was the highest. The proposed method can be used to generate the rainfall quantile maps for various return levels in the Seoul-Incheon-Gyeonggi region and other regions with similar spatial sizes.