• Title/Summary/Keyword: 방사선치료 기법

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Measurement of Dose outside a 6 MV Field Edge Using Optically Stimulated Luminescent Nano Dot Dosimeters (광자극형광나노닷선량계를 사용한 6 MV 조사야 가장자리 바깥 선량 측정)

  • Kim, Jongeon;Kim, Wontae
    • Journal of the Korean Society of Radiology
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    • v.8 no.7
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    • pp.449-454
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    • 2014
  • The purpose of this study is(was) to investigate the shielding ratio of 1 mmPb and the off axis ratio outside the field edge at depth of 1 cm from a phantom surface for 6 MV photon beam. A dose of 180 cGy was delivered to a depth of 10 cm for a $10{\times}10cm^2$ and $15{\times}15cm^2$ field in the SAD technique. The off axis ratio was calculated by measuring the dose of optically stimulated luminescent nanoDot dosimeters(OSLnDs) positioned at 2, 4 and 6 cm from the field edge, and the center axis of field. And the shielding ratio of 1 mmPb was calculated by measuring the dose of OSLnDs positioned at 2, 4 and 6 cm from the field edge.. As a result, for a $10{\times}10cm^2$ and $15{\times}15cm^2$ field, the off axis ratios were acquired 0.008-0.023 and 0.011-0.028, respectively. Also the shielding ratios of 1 mmPb were acquired 0.868-0.888 and 0.807-0.842, respectively. These results provide data to protect organs at risk outside the radiation treatment field.

Anti-Arthritic Effect of Radiation Mutant Perilla frutescens var. crispa and Atractylodes macrophala koidz. (방사선 육종 차조기와 백출 복합추출물의 항관절염 효과)

  • Park, Mi Hee;Kim, Chul Jin;Lee, Jin Young;Keum, Chang Yeop;Kim, In Seon;Jin, Chang Hyun;Ji, Joong-Gu;Kim, Sung-kyu
    • Journal of the Korean Applied Science and Technology
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    • v.37 no.1
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    • pp.102-113
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    • 2020
  • In this study, anti-arthritic effect of the mixed extract of radiation mutant Perilla frutescens var. crispa and Atractylodes macrophala koidz was investigated. Cell viability was determined by MTT assay in RAW 264.7 cells. The anti-inflammatory effect of mixed extracts was determined through measurement of the levels of reactive oxygen species (ROS) and nitric oxide (NO), release of inflammatory cytokines and expression of NF-κB, COX-2 and iNOS in LPS-induced RAW 264.7 cells after treatment of mixed extracts (5, 10, 25 ㎍/㎖). We showed that the mixed extracts was not toxic in the dose of 5, 10, 25 ug/ml, and significantly inhibited production of nitric oxide and ROS, cytokines including IL-1β, IL-6, TNF-α, and inflammatory proteins including NF-κB, COX-2 and iNOS in LPS-induced RAW 264.7 cells. Moreover, the mixed extract inhibited the type II collagen induced arthritis in DBA mice in the dose of 66.5 and 133mg/kg/day. Therefore, we suggest that mixed extract of radiation mutant Perilla frutescens var. crispa and Atractylodes macrophala koidz can be developed as a raw material for health functional food and therapeutics to treat the inflammatory arthritis.

A phantom production by using 3-dimentional printer and In-vivo dosimetry for a prostate cancer patient (3D 프린팅 기법을 통한 전립샘암 환자의 내부장기 팬텀 제작 및 생체내선량측정(In-vivo dosimetry)에 대한 고찰)

  • Seo, Jung Nam;Na, Jong Eok;Bae, Sun Myung;Jung, Dong Min;Yoon, In Ha;Bae, Jae Bum;Kwack, Jung Won;Baek, Geum Mun
    • The Journal of Korean Society for Radiation Therapy
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    • v.27 no.1
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    • pp.53-60
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    • 2015
  • Purpose : The purpose of this study is to evaluate the usefulness of a 3D printed phantom for in-vivo dosimetry of a prostate cancer patient. Materials and Methods : The phantom is produced to equally describe prostate and rectum based on a 3D volume contour of an actual prostate cancer patient who is treated in Asan Medical Center by using a 3D printer (3D EDISON+, Lokit, Korea). CT(Computed tomography) images of phantom are aquired by computed tomography (Lightspeed CT, GE, USA). By using treatment planning system (Eclipse version 10.0, Varian, USA), treatment planning is established after volume of a prostate cancer patient is compared with volume of the phantom. MOSFET(Metal OXIDE Silicon Field Effect Transistor) is estimated to identify precision and is located in 4 measuring points (bladder, prostate, rectal anterior wall and rectal posterior wall) to analyzed treatment planning and measured value. Results : Prostate volume and rectum volume of prostate cancer patient represent 30.61 cc and 51.19 cc respectively. In case of a phantom, prostate volume and rectum volume represent 31.12 cc and 53.52 cc respectively. A variation of volume between a prostate cancer patient and a phantom is less than 3%. Precision of MOSFET represents less than 3%. It indicates linearity and correlation coefficient indicates from 0.99 ~ 1.00 depending on dose variation. Each accuracy of bladder, prostate, rectal anterior wall and rectal posterior wall represent 1.4%, 2.6%, 3.7% and 1.5% respectively. In- vivo dosimetry represents entirely less than 5% considering precision of MOSFET. Conclusion : By using a 3D printer, possibility of phantom production based on prostate is verified precision within 3%. effectiveness of In-vivo dosimetry is confirmed from a phantom which is produced by a 3D printer. In-vivo dosimetry is evaluated entirely less than 5% considering precision of MOSFET. Therefore, This study is confirmed the usefulness of a 3D printed phantom for in-vivo dosimetry of a prostate cancer patient. It is necessary to additional phantom production by a 3D printer and In-vivo dosimetry for other organs of patient.

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A Case Report on Snapping Hip Patient Treated by Chuna Manual Therapy for Meridian Sinew System (경근추나 치료 후 호전된 발음성 고관절 환자 치험례)

  • Kim, Wu-Young;Lee, Jae-Young;Han, Sang-Yup;Kong, Deok-Hyun;Park, Jai-Young;Lee, Hyun-Jong
    • The Journal of Churna Manual Medicine for Spine and Nerves
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    • v.5 no.2
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    • pp.43-48
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    • 2010
  • Objectives : This study is designed to evaluate the effect of conservative oriental medical treatment using Chuna manual therapy for meridian sinew system for snapping hip patient who have hip joint movement system impairment. Methods : 28-year old snapping hip patient who have hip joint movement system impairment was treated with conservative oriental medical treatment using Chuna manual therapy for meridian sinew system. The improvement of the patient was evaluated by Numerical rating scale(NRS), Snapping Sound Degree(SSD), Range of Motion(ROM). Results: After 13 times treatment, the patient had significant improvement in Numerical rating scale(NRS), Snapping Sound Degree(SSD), Range of Motion(ROM). Conclusions: If hip joint movement system impairment cause a snapping hip, we can treat with Chuna manual therapy for meridian sinew system.

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Cephalometric study of the components of Cl III malocclusion in children 8-10 years of age (8-10세 아동에서 III급 부정교합의 구성요소에 대한 측모 두부방사선계측학적 연구)

  • Kim, Hyung-Don;Yoo, Dae-Jin;Kim, IL-Kyu;Oh, Seong-Seob;Choi, Jin-Ho;Oh, Nam-Sig;Kim, Eui-Seong
    • The korean journal of orthodontics
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    • v.30 no.2 s.79
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    • pp.159-174
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    • 2000
  • Many treatment approaches of Cl III malocclusion have been introduced and the choice of treatment should be a function of the individual problem, not of the clinician(personal preference, experience and success rate of the operator). Therefore a function of the individual problem should be analysed exactly Much has been written in the orthodontic literature concerning the nature of Cl III malocclusion. It has been reported by many investigators that a Cl III malocclusion occurs in a variety of skeletal and dental configurations by differences of race and age. Lateral cephalometric radiographs of 125 individuals were studied for the presence and distibution of four horizontal components and one vortical component in a manner similar to McNamara. The results were as follows : 1. Cl III malocclusion is not a single clinical entity. It can result from numerous combinations of skeletal and dental components. 2. Maxillary skeletal retrusion was the most common single charateristic of the Cl III sample. 3. Only a small percentage of the cases in this study exhibited maxillary dentoalveolar protrusion. 4. Only a small percentage of the cases in this study exhibited mandibular dentoalveolar retrusion. 5. Mandible was usually well-positioned, but a wide variation was observed. 6. A large percentage of the cases in this study exhibited excessive vertical development. Thus, it appears that in designing the ideal treatment regime, those approaches which might restrict vertical development and promote maxillary horizontal growth could be more appropriate in many cases.

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The Evaluation of Cerebral Executive Function Using Functional MRI (기능적 자기공명영상기법을 이용한 대뇌의 집행기능 평가)

  • Eun, Sung Jong;Gook, Jin Seon;Kim, Jeong Jae
    • Journal of the Korean Society of Radiology
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    • v.7 no.5
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    • pp.305-311
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    • 2013
  • This study involves an experiment using functional magnetic resonance imaging(fMRI) to delineate brain activation for execution functional performance. Participates to this experiment of the normal adult (man 4, woman 6) of 10 people, is not inserts the metal all closed phobia and 24.5 year-old average ages which the operating surgeon experience which are not they were. The subject for a functional MRI experiment word -color test prosecuting attorney subject rightly at magnetic pole presentation time of 30 first editions and after presenting, uses SPM 99 programs and the image realignment, after executing a standardization (nomalization), a difference which the signal burglar considers the timely order as lattice does, pixel each image will count there probably is, in order to examine rest and active crossroad dividing independence sample t-test (p<.05). Overlapped in this standard anatomic image and got a brain activation image from level of significance 95%. With functional MRI resultant execution function inside being relation, the prefrontal lobe, anterior cingulate gyrus, parietal lobe, orbitofrontal gyrus, temporal lobe, parietal lobe was activated. The execution function promotes a recovery major role from occupational therapy, understanding about the damage mechanism is important. When confirms the brain active area which accomplishes an execution function brain plasticity develops the cognitive therapeutic method which is effective increases usefully very, will be used.

The Usefulness of Deconvolution Perfusion CT in Patients with Acute Cerebral Infarction : Comparison with Diffusion MRI (급성 뇌경색 환자에서 Deconvolution perfusion CT의 유용성 : Diffusion MRI와 비교)

  • Eun, Sung-Jong;Kim, Young-Keun
    • Journal of radiological science and technology
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    • v.26 no.3
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    • pp.25-31
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    • 2003
  • This study was performed to evaluate the usefulness of Deconvolution perfusion CT in patients with acute cerebral infarction. Nine patients with acute cerebral infarction underwent conventional CT and cerebral perfusion CT within 23 hours of the onset of symptoms. The perfusion CT scan for each patient was obtained at the levels of basal ganglia and 1cm caudal to the basal ganglia. By special imaging software, perfusion images including cerebral blood volume(CBV), cerebral blood flow(CBF), and mean transit time(MTT) maps were created. The created lesions were evaluated on each perfusion maps by 3 radiolocical technician. MTT delay time was measured in the perfusion defect lesion and symmetric contralateral normal cerebral hemisphere. Lesion sire were measured on each perfusion map and compared with the value obtained by diffusion weighted MR imaging(DWMRI). All perfusion CT maps showed the perfusion defect lesion in all patients. There were remarkable CT delay in perfusion defect lesion. In comparison of lesion size between each perfusion map and DWMRI, the lesion on CBF map was the most closely correlated with the lesion on DWMRI(7/9). The size of perfusion defect lesion on MTT map was larger than that of lesion on DWMRI, suggesting that m map can evaluate the ischemic penumbra. Deconvolution Perfusion CT maps make it possible to evaluate not only ischemic core and ischemic penumbra but also hemodynamic status in perfusion defect area. These results demonstrate that perfusion CT can be useful to the diagnosis and treatment in the patients with acute cerebral ischemic infarction.

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GLCM Algorithm Image Analysis of Nonalcoholic Fatty Liver and Focal Fat Sparing Zone in the Ultrasonography (초음파검사에서 비알콜성 지방간과 국소지방회피영역에 대한 GLCM Algorithm 영상분석)

  • Cho, Jin-Young;Ye, Soo-Young
    • Journal of radiological science and technology
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    • v.40 no.2
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    • pp.205-211
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    • 2017
  • There is a need for aggressive diagnosis and treatment in middle-aged and high-risk individuals who are more likely to progress from nonalcoholic fatty liver to hepatitis. In this study, nonalcoholic fatty liver was divided into severe, moderate, and severe, and classified by quantitative method using computer analysis of GLCM algorithm. The purpose of this study was to evaluate the characteristics of ultrasound images in the local fat avoidance region. Normal, mild, moderate, severe fatty liver, and focal fat sparing area, 80 cases, respectively. Among the parameters of the GLCM algorithm, the values of the Autocorrelation, Square of the deviation, Sum of averages and Sum of variances with high recognition rate of the liver ultrasound image were calculated. The average recognition rate of the GLCM algorithm was 97.5%. The result of local fat avoidance image analysis showed the most similar value to the normal parenchyma. Ultrasonography can be easily accessed by primary screening, but there may be differences in the accuracy of the test method or the correspondence of results depending on proficiency. GLCM algorithm was applied to quantitatively classify the degree of fatty liver. Local fat avoidance region was similar to normal parenchyma, so it could be predicted to be homogeneous liver parenchyma without fat deposition. We believe that GLCM computer image analysis will provide important information for differentiating not only fatty liver but also other lesions.

The Dose and Risk Reduction from Adoption of Automatic mA Control in 4D CT Scans (자동전류조절기능을 사용한 4D CT 촬영시 선량 및 위험도 저감 효과)

  • Ko, Young Eun;Je, Hyoung Uk;Hwang, Yeon;Park, Sung Ho
    • Progress in Medical Physics
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    • v.26 no.4
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    • pp.267-272
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    • 2015
  • In this study, the reduction of dose and risk was evaluated from using automatic mA control in 4D CT scan of patients whose organ movement was considered for gated radiotherapy. The organ doses, CTDI, effective doses from 4D CT with and without using automatic mA control were evaluated using CT-Expo program for each 10 patients of liver and lung cancer, and the risk of exposure induced death and loss of life expectancy were evaluated using PCXMC program. It was founded that there were 26.8%, and 15.5% dose reduction in organ doses and CTDI for liver and lung cancer patients and 16.5% and 19.8% risk reduction in liver and lung cancer patients. The organ doses and effective doses were evaluated for the parameter of each patient used in CT scans, and risks considering age and gender could be evaluated. It was founded that there were 21.2% dose reduction and 18.2% risk reduction in 4D CT scan using AEC for liver and lung cancer patients.

A comparison between the modified Brostrom procedure using single and double suture anchor for chronic lateral ankle instability (발목관절 외측 불안정성에서 단일 봉합나사와 이중 봉합나사를 이용한 변형 Brostrom 술식간의 임상결과 비교)

  • Shon, Hyun-Chul;Cho, Byung-Ki;Kim, Yong-Min;Kim, Dong-Soo;Choi, Eui-Sung;Park, Kyoung-Jin;Park, Ji-Kang
    • Journal of Korean Orthopaedic Sports Medicine
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    • v.10 no.2
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    • pp.69-77
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    • 2011
  • Purpose: This study was retrospectively performed to compare the clinical outcomes of modified Brostrom procedures using the single suture anchor and the double suture anchor for chronic lateral ankle instability. Materials and Methods: Thirty-seven patients were followed up for more than 1 year after the modified Brostrom procedures using suture anchor. Single surgeon treated seventeen cases with single suture anchor and 20 cases with double suture anchor. The clinical evaluation was performed according to the Karlsson scale and Sefton grading system. Radiologic measurement of the talar tilt and anterior talar translation was performed through anterior and varus stress radiographs using Telos device. Results: The Karlsson scale had improved significantly from preoperative average of 45.2 points to 89.4 points in single suture anchor group, and from 46.4 points to 90.5 points in double suture anchor group. According to the Sefton grading system, 15 cases (88.2%) in single suture anchor group and 18 cases (90%) in double suture anchor group achieved satisfactory results. The talar tilt angle and anterior talar translation had improved significantly from preoperative average of $13.6^{\circ}$ and 8.6 mm to $5.4^{\circ}$ and 4.1 mm in single suture anchor group, from $14.1^{\circ}$ and 8.4mm to $3.9^{\circ}$ and 4 mm in double suture anchor group. Double suture anchor technique was significantly superior in postoperative talar tilt. Conclusion: Single and double suture anchor techniques produced similar clinical and functional outcomes except for talar tilt, which was significantly superior in double suture anchor group. Both modified Brostrom procedures using the single and double suture anchor appear to be effective treatment methods for chronic lateral ankle instability. Further evaluation of clinical outcomes and biomechanical studies in athletes are needed.

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