• Title/Summary/Keyword: 반응도(R)

Search Result 3,012, Processing Time 0.031 seconds

Preparation of Spherical TiO2 Nanoparticles Using Amphiphilic PCZ-r-PEG Random Copolymer Template Membrane (양친성 PCZ-r-PEG 랜덤 공중합체 분리막을 이용한 구형 이산화티타늄 나노입자의 제조)

  • Lee, Jae Hun;Patel, Rajkumar
    • Membrane Journal
    • /
    • v.29 no.3
    • /
    • pp.183-189
    • /
    • 2019
  • Amphiphilic PCZ-r-PEG random copolymer assisted solvothermal process is used to prepare mesoporous $TiO_2$ microspheres generated from nanoparticles by self-assembly method. Synthesized PCZ-r-PEG is characterized by Fourier transform infrared spectroscopy (FT-IR), nuclear magnetic resonance (NMR), gel permeation chromatography (GPC) and transmission electron microscopy (TEM). The mesoporous $TiO_2$ are prepared by PCZ-r-PEG, glucose, water in tertrahydrofuran solution at $150^{\circ}C$ for 12 h and the $TiO_2$ microspheres are calcined at $550^{\circ}C$ for 30 min to further crystallize and organic residue are removed. Morphology and crystallization phase is characterized by scanning electron microscopy (SEM) and X-ray diffraction (XRD) respectively. The mesoporous $TiO_2$ crystallized in pure anatase phase with diameter of $300{\pm}20nm$.

Comparison of Radiation Adaptive Responses in Peripheral Lymphocytes of Patients Undergoing Tc-99m MDP and Tc-99m DTPA Scintigraphies (Tc-99m MDP와 Tc-99m DTPA 신티그라피를 시행한 환자의 말초혈액 림프구에서 유도되는 방사선 적응반응의 비교)

  • Bom, Hee-Seung;Li, Ming-Hao;Min, Jung-Jun;Kwon, An-Sung;Kim, Ji-Yeul
    • The Korean Journal of Nuclear Medicine
    • /
    • v.34 no.3
    • /
    • pp.252-259
    • /
    • 2000
  • Purpose: The purpose of this study was to compare the radiation adaptive response (RAR) in peripheral lymphocytes (PL) of patients induced by Tc-99m MDP and Tc-99m DTPA scintigraphies. Materials and Methods: Lymphocytes from 45 patients (25 males, 20 females, mean age $44{\pm}18$ years) were collected before and after scintigraphies using 740 MBq Tc-99m MDP (n=22) or Tc-99m DTPA (n=23). Lymphocytes from 20 controls (12 males, 8 females, mean age $43{\pm}7$ years) were also collected. They were exposed to challenge dose of 2 Gy ${\gamma}-rays$ using a Cs-137 cell irradiator Number of ring-form (R) and dicentric (D) chromosomes was counted under the light microscope. From them a representative score, Ydr, was calculated as Ydr=(D+R)/cells. Adaptation index (AI) was defined as difference of Ydr between unconditioned and conditioned lymphocytes. Ydr was also measured after an administration of cycloheximide (CHM), a protein synthesis inhibitor, before challenge dose. Results: RAR was induced in both groups of patients. CHM abolished the adaptive response in both groups. AI of Tc-99m MDP group was significantly higher than that of Tc-99m BTPA group. Conclusion: Tc-99m MDP induced RAR was more prominent than those induced by Tc-99m DTPA.

  • PDF

A Study of Nitrous Oxide Decomposition using Calcium Oxide (Calcium Oxide를 이용한 N2O 분해에 관한 CO2의 영향 연구)

  • Paek, Jin-Young;Park, Yeong-Sung;Shun, Dowon;Bae, Dal-Hee
    • Korean Chemical Engineering Research
    • /
    • v.40 no.6
    • /
    • pp.746-751
    • /
    • 2002
  • Fluidized bed combustion is a coal combustion technology that can reduce both SOx and NOx emission; SOx is removed by limestone that is fed into the combustion chamber and the NOx is reduced by low temperature combustion in a fluidized bed combustor and air stepping, but $N_2O$ generation is quite high. $N_2O$ is not only a greenhouse gas but also an agent of ozone destruction in the stratosphere. The calcium oxide(CaO) is known to be a catalyst of $N_2O$ decomposition. This study of $N_2O$ decomposition reaction in fixed bed reactor packed over CaO bed has been conducted. Effects of parameters such as concentration of inlet $N_2O$ gas, reaction temperature, CaO bed height and effect of $CO_2$, NO, $O_2$ gas on the decomposition reaction have been investigated. As a result of the experiment, it has been shown that $N_2O$ decomposition reaction increased with the increasing fixed bed temperature. While conversion of the reaction was decreased with increasing $CO_2$ concentration. Also, under the present of NO, the conversion of $N_2O$ decomposition is decreased. From the result of kinetic study gained the heterogeneous reaction rate on $N_2O$ decomposition. In the case of $N_2O$ decomposition over CaO, heterogeneous reaction rate is. $\frac{d[N_2O]}{dt}=\frac{3.86{\times}10^9{\exp}(-15841/R)K_{N_2O}[N_2O]}{(1+K_{N_2O}[N_2O]+K_{CO_2}[CO_2])}$. In this study, it is found that the calcium oxide is a good catalyst of $N_2O$ decomposition.

COMPARISON OF DEVELOPMENTAL AND PSYCHOPATHOLOGlCAL CHARACTERISTICS FOR RAD AND PDD CHILDREN (반응성 애착장애 아동과 전반적 발달장애 아동의 발달 및 정신병리학적 특징의 비교연구)

  • Yoon, Hyun-Sook;Choi, Jin-Sook;Kim, Tae-Ryeon;Hong, Kang-E
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
    • /
    • v.3 no.1
    • /
    • pp.3-13
    • /
    • 1992
  • For the purpose of better understanding of RAD children, comparisons were performed about the developmental and psychopathological characteristics between RAD and PDD children. Study subjects were the children between the ages 2 and 6. who visitied SNUCH Child and Adolescent Psychiatry OPD or treated in Day Treatment Center during May, 1989 and Sep., 1991, diagnosed by the child psychiatrist as RAD or PDD according to DSM-III-R diagnostic criteria. A total of 40 children were included in the study. 20 were RAD(18 boys, 2 girls). 20 were PDD(20 boys). PEP was performed to all study subjects, by the raters blind to psychiatric diagnosis of each. And analysis was done about the level of developmental functioning score and psychopathological scores between RAD and PDD children. The results are as follows 'There were retardation on the general developmental functioning in RAD children, and the severity of retardation were lined up as perceptual ability>imitation>gross motor>cogitive language>eye-hand coordination>fine motor. Characteristics of psychopathology in RAD children were lined up by severity as language>play>relationship>affection >sensory. Group differences of the two shows on PDD group rejection score was significantly higher on the perception item. while RAD was superior on the perception emerging response. Differences of the psychopathology between two groups were on such areas as ; Affection, which was significantly higher on 'Absent' in RAD, while significantly higher on 'severe' in PDD children. On the interest for the play and materials. sensory and language areas, RAD children were significantly higher ratings on 'Absent' than PDD children.

  • PDF

Correlation of Pre-treatment FDG Uptake to Therapeutic Response and Relapse in Patients with Small Cell Lung Cancer (소세포폐암의 치료전 FDG섭취와 치료반응 및 재발과의 연관성)

  • Seo, Young-Soon;Kwon, Seong-Young;Jeong, Shin-Young;Song, Ho-Chun;Min, Jung-Joon;Kim, Kyu-Sik;Kim, Young-Chul;Bom, Hee-Seung
    • Nuclear Medicine and Molecular Imaging
    • /
    • v.41 no.6
    • /
    • pp.538-545
    • /
    • 2007
  • Purpose: We evaluated correlation of $^{18}F$-FDG uptakes, therapeutic response and relapse in pre-treatment $^{18}F$-FDG PET/CT in patients with SCLC. Materials and methods: We included 26 patients with pathologically proven small cell lung cancer. Total 102 lesions (26 lungs, 69 lymph nodes and 8 metastatic lesions) were evaluated. All patients underwent $^{18}F$-FDG PET/CT for staging. The maxSUV was used as a parameter of $^{18}F$-FDG uptake. The patients were divided into responders and non-responders according to response criteria on chest CT scan after 3 cycles of chemotherapy. We compared maxSUV between two groups by using independent t-test. To access correlation with $^{18}F$-FDG uptake and relapse, maxSUV and interval time to relapse was analyzed by correlation analysis. The cutoff value of maxSUV was evaluated by ROC curve. Results: Twelve-one patients (81%) were responders and five patients were non-responders on follow-up chest CT scan. The mean maxSUV of main lung lesions in responders and non-responders were $14.15{\pm}3.72$ and $9.17{\pm}2.15$, respectively. The maxSUV in the responders was significantly lower than that in non-responders (p<0.05). According to ROC curve, point of cut that predicts therapeutic response was 8.98 with 100% sensitivity and 57% specificity. The correlation analysis between $^{18}F$-FDG uptakes and interval time to relapse showed a significant negative correlation (p<0.05, r=-0.757). Conclusion: The pre-treatment $^{18}F$-FDG uptake of responders was significantly lower than that of non-responders. Patients with high $^{18}F$-FDG uptake in pre-treatment $^{18}F$-FDG PET/CT relapse earlier.

A Kinetic Study of Steam Gasification of Woodchip, Sawdust and Lignite (나무칩, 톱밥 바이오매스와 갈탄의 수증기 가스화반응 특성 연구)

  • Kim, Kyungwook;Bungay, Vergel C.;Song, Byungho;Choi, Youngtai;Lee, Jeungwoo
    • Korean Chemical Engineering Research
    • /
    • v.51 no.4
    • /
    • pp.506-512
    • /
    • 2013
  • Biomass and low-grade coals are known to be better potential sources of energy compared to crude oil and natural gas since these materials are readily available and found to have large reserves, respectively. Gasification of these carbonaceous materials produced syngas for chemical synthesis and power generation. Woodchip, sawdust and lignite were gasified with steam in a thermobalance reactor under atmospheric pressure in order to evaluate their kinetic rate information. The effects of gasification temperature ($600{\sim}900^{\circ}C$) and partial pressure of steam (20~90 kPa) on the gasification rate were investigated. The three different types of gas-solid reaction models were applied to the experimental data to predict the behavior of the gasification reactions. The modified volumetric model predicted the conversion data well, thus the model was used to evaluate kinetic parameters in this study. The observed activation energy of biomass, sawdust and lignite gasification reactions were found to be in reasonable range and their rank was found to be sawdust > woodchip > lignite. The expression of apparent reaction rates for steam gasification of the three solids was proposed to provide basic information on the design of coal gasification processes.

A Study on the Treatment of Leachate Using Combined Membrane Process (조합형 분리막공정을 이용한 침출수 처리에 관한 연구)

  • 강문선;최광호;손성섭
    • Membrane Journal
    • /
    • v.10 no.4
    • /
    • pp.213-219
    • /
    • 2000
  • In order to resolve the problem of aged land[jlJ leachate treatment, limitation in removal of non-biodegradable materials and denitrification caused by carbon source shortage, we applied combined process consisted of 5MBR and RO to leachate treatment. We perfonned 5MBR pilot plant tests on Yongin City for a period of about lOOdays, demonstrated the performance of the SlVlUR process (($NH_3$-N removal efficiency; 90%). But there was also limitation to removal of non-biodegradable materials and denitrification. In full-scale plant we observed the IXrformance of combined process (SMI3R + R/O) in order to confirm the expected treatment efficiencies. Their results were approximately 98%, 94% of treatment efficiency in case of $COD_{Cr}$(<3 mg/L) and TN(<50 mg/L)respectively and the results of treatment were stable.

  • PDF

The Characteristics Analysis and Manufacture of Metal Explosive(ZPP) on PMD (PMD용 금속화약(ZPP) 제조 및 특성분석)

  • Shim, Jungseob;Kim, Sangbaek;Ahn, Gilhwan;Kim, Junhyung
    • Journal of the Korean Society of Propulsion Engineers
    • /
    • v.20 no.3
    • /
    • pp.25-31
    • /
    • 2016
  • This research investigated the manufacturing process and characteristics analysis of ZPP(Zirconium Potassium Perchlorate) as pyrotechnic are commonly found in the aerospace, defense, and automotive industries. A solid pyrotechnic mixture is composed of an oxidizing agent, fuel, and binder. Precipitation process was used to uniformly mix the raw material. Through the analysis of the material characteristics and thermal response is designed optimum ratio by NASA CEA program. It was compared by performing the evaluation of these size, shape and calorimetry characteristics.

Ketoprofen ethyl ester에 대해 높은 광학 선택성을 갖는 (R)- 과 (S)-stereospecfic esterase들의 클로닝과 서열분석 및 발현

  • Kim, Ji-Yeon;Choe, Gi-Seop;Kim, Geun-Jung;Yu, Yeon-U
    • 한국생물공학회:학술대회논문집
    • /
    • 2001.11a
    • /
    • pp.625-628
    • /
    • 2001
  • To isolate novel strains that hydrolyzed the rac-ketoprofen ethyl ester to ketoprofen in the stereospecific manner, we screened broad ecological niches and soil samples in which the activity was expected to be found. From thousands of strains, we isolated a Pseudomonas sp. S34 producing a (S)-stereospecific esterase, and a thermostable esterase with (R)-form selectivity was also 。 btained from Bacillus stearothermophilus JYl44. To further analyse the gene structure and to induce a high level expression, two genes from each strain were cloned and sequenced. BLAST search results with the esterase gene from 534 revealed that both of gene (80-84 %) and amino acid sequences (89- 95 %) were highly conserved in the related esterases from Pseudomonas strains (fluorescens and aeruginosa). The thermostable esterase from JY144, however, revealed a relative low homology (45-52 %) to other esterase and/or lipase from related strains. Obviously, a complete conversion with pure enantiomer (R - or S) were readily achieved by recombinant clones expressing either (R)- or (S)- stereospecific esterase.

  • PDF

Effect of Lactobacilli on Reactive Oxygen Scavenging and Immune Stimulation (유산균의 활성산소 소거 및 면역증강효과)

  • lee, Ho;Yang, Seung-Gak;Park, Soo-Nam;Jeon, Do-Yong
    • KSBB Journal
    • /
    • v.7 no.4
    • /
    • pp.290-295
    • /
    • 1992
  • Reactive oxygen scavenging activity and immune stimulatory activity of lactobacilli were investigated by different free radical scavenging assays and Ig G assay. Lactobacilli culture (S/N) and its complex with $Mn^{2+}$ have significant effects in XOD assay and response to paraquat. Cell free extract significantly prevented the photohemolysis. Thus, it seems that each sample from lactobacilli has a different free radical scavening mechanism. Furthermore, it is assumed that cell free extract from lactobacilli activates antibody stimulation of B cell through a stimulation of T cell.

  • PDF