• Title/Summary/Keyword: 바이오 조직

Search Result 1,784, Processing Time 0.027 seconds

DERMOID CYST IN AN INFANTILE UPPER LIP (영아의 상순에 발생한 유피낭종)

  • Kim, Seong-Oh;Moon, Sung-Hwan;Lee, Jae-Ho;Choi, Hyung-Jun;Choi, Byung-Jai
    • Journal of the korean academy of Pediatric Dentistry
    • /
    • v.31 no.3
    • /
    • pp.501-505
    • /
    • 2004
  • Dermoid cyst is a developmental cyst that is lined by epidermis-like epithelium and contains dermal adnexal structures in the cyst wall. Dermoid cyst most occur in the eye brow although occasionally develop in other locations such as midline of the floor of the mouth, tongue, lip and buccal mucosa. The lesion is slow growing and painless without lympadenopathy. The contents of the dermoid cyst can be caseous or sebaceous. The size can vary from a few millimeters to 12cm in diameter. Histologically, dermoid cyst is lined by epidermis and adnexaes such as sweat gland, sebaceous glands and hair follicles are present in the cyst wall. The 2-year-old female of this case visited Department of Pediatric Dentistry, College of Dentistry, Yonsei University with a chief complaint of the emergence of mass on her upper lip. An excisional biopsy was carried out for a histological examination and sebaceous gland was observed in the cyst wall. The lesion was diagnosed as dermoid cyst. Dermoid cyst does not recur if complete excision is accomplished.

  • PDF

Overexpression of MicroRNA-31 as a Promising Biomarker for Prognosis and Metastasis in Human Colorectal Cancer (MicroRNA-31 과발현을 이용한 대장암의 예후예측 및 전이예측 바이오마커 발굴)

  • Hur, Keun
    • Journal of Life Science
    • /
    • v.26 no.6
    • /
    • pp.705-710
    • /
    • 2016
  • Colorectal cancer (CRC) is the third most common cancer and a leading cause of cancer-related death worldwide. Although several diagnostic and therapeutic tools have been available, CRC remains difficult to complete cure because of insufficient understanding of the molecular mechanisms underlying this disease progression. MicroRNAs (miRNAs) are small non-coding RNA molecules that strongly regulate gene expression via transcriptional and translational control mechanisms. Many crucial cellular pathways are frequently disrupted in cancer development process due to dysregulation of several miRNAs. Mir-31 functions as an oncogene that modulate expression of multiple cancer related genes. Thus, we aimed to demonstrate clinical relevance of miR-31 in human CRC. Quantitative RT-PCR analysis of miR-31 expression was performed in 175 CRC tissues and 16 normal colonic mucosa (NM). Next, we investigated clinical significances of miR-31 expression in various clinicopathologic features in CRC patients cohort. Mir-31 was significantly up-regulated in CRC tissues compared to NM. In CRC tissues, miR-31 expression level was significantly elevated in a stage-dependent manner, which was associated with poor survival in patients with CRC. High miR-31 levels in CRC tissues significantly correlated with poor prognosis (hazard ratio [HR]=2.4) as well as distant metastasis (odds ratio [OR]=2.3). In conclusion, we identified clinical significance of miR-31 expression in CRC. High miR-31 expression may be clinically able to use as a biomarker for CRC prognosis and predicting metastasis.

The Impact of Employees' Emotional Intelligence on Job Crafting: Focus on Mediating Effect of Self-efficacy and Moderating Effect of Career Growth Opportunities (감성지능이 조직 구성원의 Job Crafting에 미치는 영향 : 자기효능감의 매개효과와 경력성장기회의 조절효과 중심으로)

  • Lee, Ji-Hye;Cho, Dong-Sung;Oh, Sang-Jin
    • The Journal of the Korea Contents Association
    • /
    • v.17 no.5
    • /
    • pp.658-676
    • /
    • 2017
  • The purpose of this study is to suggest importance of emotional intelligence by studying effects between emotional intelligence and job crafting; the research was conducted among employees working for organizations. Especially this empirical study proves mediating effect of self-efficacy, and moderating effect of career growth opportunities in relationship between emotional intelligence and job crafting. The survey was conducted for employees; 341 answers were used from total population and were analyzed by SPSS 24.0 and AMOS 24.0 statistics package. The study concludes that emotional intelligence has positive influence (+) on job crafting of employee. Positive influence was found in the relationship between emotional intelligence and self-efficacy, and job crafting as well. The study also proves mediating effect of self-efficacy. Moreover it is likely that career growth opportunities have moderating effect in the relationship between self-efficacy and job crafting. The study implies that improving emotional intelligence is important to change attitude/behavior of employees on job. The study also implies that corporations need to provide career growth opportunities, to develop various programs, and to create friendly working environment.

The Effect of Both Organizational Change Awareness of Public Agency Relocation and Public Service Motivation on Job Attitude : Focused on the Employees of Electric Power Public Enterprise to be Relocated (공공기관 지방이전이라는 조직변화에 대한 인식과 공공봉사동기가 직무태도에 미치는 영향 : 전력공기업의 지방이전 대상자를 중심으로)

  • Lee, Joon Tae;Ha, Kyu Soo
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
    • /
    • v.9 no.5
    • /
    • pp.205-219
    • /
    • 2014
  • To follow the government policy on 'balanced development of county', the employees of public agencies to be relocated should get used to the new working and living environments such as changing their homes or living away from their family. This study aims to figure out the awareness of the employees of public agencies to be relocated on such organizational change with Person-Organization fit concept and then to find out the effect of positive or negative awareness on job attitude such as organizational commitment and turnover intention. It is expected that public service motivation, the intrinsic motivation for public employees, positively acts as a medium between the awareness of organizational change and job attitude, which this study confirms through an empirical analysis of the employees of electric power public enterprise to be relocated. This study proves that firstly the awareness on organizational change is not directly related to organizational commitment, however, it affects directly turnover intention and public service motivation as an immediate cause and secondly public service motivation has a positive correlation to organizational commitment but it doesn't affect turnover intention and lastly organizational commitment has a negative correlation to turnover intention. Besides, this study empirically finds out that public service motivation has mediating effect which is significantly affects the awareness of organizational change, organizational commitment and turnover intention, and organizational commitment has mediating effect between public service motivation and turnover intention as well.

  • PDF

A Study on Job Satisfaction and Organizational Commitment According to MBTI Personality Types (MBTI 성격유형에 따른 직무만족과 조직몰입에 관한 연구)

  • Lee, Han-Na;Shin, Dong-Ju
    • Korean Business Review
    • /
    • v.23 no.2
    • /
    • pp.77-98
    • /
    • 2010
  • While machines can replace general industries, it is impossible to do so in service industries in which require various contacts with clients. As automated system would not work in service industries, it requires more of reliance to human resources than other industries. The services done here for customers are consequently reflected to the level of customers' satisfaction and business performance. Thus, highly qualified services are important factors for the success in the industry, but the problem here is that there is not enough care for employees providing those services. Therefore, this study analyzes employees' personalities and shows how those affect to job satisfaction and organizational commitment. It also aims at showing present problems in companies. MBTI, a test showing one's character, has been applied for the analysis, and surveys have been provided to employees to see how their personalities affect to job satisfaction and organizational commitment. Through this process, job satisfaction in accordance with one's character and organizational commitment is partially similar, and the hypothesis assuming that there is interrelationship between job satisfaction and organizational commitment was proved.

  • PDF

A Study on Moderate Effecting of LMX on the Relationships between Appraisal Justice and Organization Commitment (고과공정성이 조직몰입에 미치는 영향에 있어서 상사-부하간 교환관계의 조절효과에 관한 연구)

  • Enkh-Otgon., D.;Jeon, Dong-Cheol
    • Journal of Digital Convergence
    • /
    • v.12 no.12
    • /
    • pp.139-149
    • /
    • 2014
  • This paper aims to examine the moderate effects of LMX on the relationships between appraisal justice and organization commitment. Additionally, This study is to identify the influences of appraisal justice on the organization commitment in the organization. To accomplish these purposes, the main factors of the appraisal justice such as distributive justice, procedural justice and interactional justice were found from the previous studies. This study used the statistical techniques such as descriptive analysis, reliability analysis, discriminant analysis, factor analysis, correlation analysis, multi regression analysis, and hierarchical regression analysis. The following are the summary of hypothesis test: First, all three justice factors are essential to enhance the level of organizational commitment in appraisal about employee of enterprises. Second, interactional justice among factors of appraisal justice have differential influence on organization commitment by LMX.

Structural Relationship among Self Leadership, Attitude and Customer Orientation of Employees in Travel Agency (여행사 종사원의 셀프리더십, 태도 및 고객지향성의 구조적 관계)

  • Baek, Hyun;Kim, Yong-Soon
    • The Journal of the Korea Contents Association
    • /
    • v.10 no.5
    • /
    • pp.398-406
    • /
    • 2010
  • The purpose of this study was to research the relationships among self-leadership, job satisfaction, organizational commitment and customer orientation one of the performance variables of employees in travel agency. As more and more travel agency organizations move toward competitive environments, organizational members at all levels are being encouraged to take greater responsibility for their own job tasks and work behaviors. Self-leadership involves the influence people exert over themselves to achieve the self-motivation and self-direction needed to accomplish desirable outcomes. To accomplish this study, it was determined that the analysis derived from a hypothesis and literature reviews and data collected from 206 employees in travel agency.The results of empirical analysis showed as follows. First, Self-leadership has a significant effect on job satisfaction, organizational commitment and customer orientation. Second, Job satisfaction has a significant effect on organizational commitment and customer orientation. Third, Organizational commitment has a significant effect on customer orientation. Based on these findings, the implications and limitations of the study were presented including some directions for future studies.

A Study on the storage of Fresh Fruits and Vegetables (Part II) Effects of Intercellular atmosphere and Ethylene evolution by control of external pressure and gas composition in Apple Fruits. (청과물 저장에 관한 연구(제 2보) -사과 저장에 있어서 환경압력 및 기체조성이 사과조직내 기체조성과 Ethylene 생성에 미치는 영향-)

  • 손태화;최종욱;서온수
    • Microbiology and Biotechnology Letters
    • /
    • v.1 no.1
    • /
    • pp.25-30
    • /
    • 1973
  • Experiments were carried out to clarify changes of intercellular gas composition, respiration and ethylene evolution by controlled external atmospheric pressure and external gas composition on apples. Jonathan apples, harvested 25, in September and Rolls apples, harvested 25, in October, 1971 and 1972 were used. Results obtained were as follows: 1. Intercellular gas volumes were proportionally changed by the given pressure, and the given pressure remarkably affected internal gas composition and volume of apples. As intercellular gas volumes were reached in their equilibrium within 5 min. after treatment, the internal atmospheric conditions became constant rapidly. 2. The increase of internal $CO_2$ production was co-related with an amount of internal $O_2$ consumption, therefore, the decreasing period of internal $O_2$ consumption was equalled to the period of climacteric rise in respiration. 3. The increasing of $CO_2$ production followed evolution of $C_2$H$_4$ and this phenomenon on SAP part. was subsequent to NAP part 4. In sub-atmospheric storage, CA effect was also obtained by control of low $O_2$ and high $CO_2$ concentration.

  • PDF

Primary Malignant Fibrous Histiocytoma of the Diaphragm -One Case Report- (횡격막의 원발성 악성 섬유성 조직구종 -1례 보고-)

  • 김대현;김범식;조규석;박주철
    • Journal of Chest Surgery
    • /
    • v.36 no.2
    • /
    • pp.118-121
    • /
    • 2003
  • A 25-year-old female patient was adimitted due to discomfort in the right chest and left epigastric area. Chest X-ray and chest CT showed a round 4$\times$4$\times$4cm sized mass located in the right lower lobe and abutted on the right diaphragm and metastatic lesions in the right lower lobe and right middle lobe. In exploratory thoracotomy, we discovered a mass originating from the right diaphragm which directly invaded the right lower lobe and metastatic subpleural lesions in the right lower lobe and right middle lobe. The mass was diagnosed as sarcoma by frozen section biopsy and we removed the mass by on bloc resection of the right diaphragm and right lower lobe. Metastatic subpleural lesions in the right lower lobe and right middle lobe were removed by wedge resection. The mass was malignant fibrous histiocytoma of the diaphragm in permanent pathologic examination and chemotherapy was done as adjuvant measure. We report one extremely rare case of malignant fibrous histiocytoma of the diaphragm with literature.

취장 외분비기능 부전에서 합성 단백 분해효소 억제 물질에 대한 취조직 재생 및 기능 변동 연구

  • 김경환
    • Proceedings of the Korean Society of Applied Pharmacology
    • /
    • 1993.04a
    • /
    • pp.84-84
    • /
    • 1993
  • 취장 외분비 기능 부전은 임상적으로 영양결핍, 발육부전, 지방변동을 유발하나 이의 치료로는 결려된 소화효소 보충 등 보존적 요법만 시행될 뿐 근본적인 치료법은 없는 실정이다. 지난해 과제는 합성 단백분해 억제물질인 Camostat이 취장의 비대와 중식을 일으키며 또한 단백분해 효소분비를 증가시킴을 보고한 바 있다. 이를 토대로 최근 보고된 실험적 취장 외분비기능 부전 모델을 이용하여 camostat의 효과를 검색하고자 하였으며 아울러 이를 CCK효과와 비교하였다. 실험동물로는 몸무게 200 g 안팎의 수컷 Sprague-Dawley계 흰쥐를 사용하였으며 취장기능 부전은 oleic acid (25 $\mu$/100 g bw)를 취관내 주입하여 유발하였다. Camostat은 200 mg/kg씩 위내 투여(i.g.)하였으며 CCK(CCK-8)는 5 $\mu\textrm{g}$/kg씩 하루 2회 피하주사하였고 투여기간은 각각 3, 7, 14 일간으로 하였다. 각 약물 투여 후 취장 외분비 기능과 조직학적 검색을 실시하여 다음과 같온 결과를 얻었다. 1. Oleic acid의 취관내 주입으로 흰쥐의 취장 무게, 조직내 효소단백 함량 및 효소분비량이 현저히 감소되었고 조직학적으로 심한 위축과 섬유화를 관찰할 수 있었으며 이는 주입 후 기간이 지남에 따라 계속 진행하였다. 2. 취장기능 부전 유발 흰쥐에서 camostat 처치로 조직내 효소단백 함량 및 효소분비가 증가 되었으며 이는 14일간 처치군에서 뚜렷하였다. 3. 취장 기능부전 유발 횐쥐에서 camostat 처치는 조직학적으로 기능적인 외분비 조직이 유지되었으며 이는 3일군에서 특히 뚜fut하였다. 4. 취장기능부전 유발 횐쥐에서 CCK 처치효과는 camostat 처치효과와 비슷하였다. 이상의 결과로 보아 oleic acid 주입은 취장기능부전 연구에 유용한 실험모델로 생각되며 합성 단백 분해 효소 억제제인 Camostat은 취장외분비 기능 부전의 진행을 억제하고 어느정도 그 기능을 호전시킬 수 있으며 이는 CCK유리에 기인한다고 생각한다.

  • PDF