• Title/Summary/Keyword: 바이오 영감

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A Genetic Algorithm for Production Scheduling of Biopharmaceutical Contract Manufacturing Products (바이오의약품 위탁생산 일정계획 수립을 위한 유전자 알고리즘)

  • Ji-Hoon Kim;Jeong-Hyun Kim;Jae-Gon Kim
    • The Journal of Bigdata
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    • v.9 no.1
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    • pp.141-152
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    • 2024
  • In the biopharmaceutical contract manufacturing organization (CMO) business, establishing a production schedule that satisfies the due date for various customer orders is crucial for competitiveness. In a CMO process, each order consists of multiple batches that can be allocated to multiple production lines in small batch units for parallel production. This study proposes a meta-heuristic algorithm to establish a scheduling plan that minimizes the total delivery delay of orders in a CMO process with identical parallel machine. Inspired by biological evolution, the proposed algorithm generates random data structures similar to chromosomes to solve specific problems and effectively explores various solutions through operations such as crossover and mutation. Based on real-world data provided by a domestic CMO company, computer experiments were conducted to verify that the proposed algorithm produces superior scheduling plans compared to expert algorithms used by the company and commercial optimization packages, within a reasonable computation time.

An Error Detection and Recovery Algorithm in Digital Circuit Mimicking by Self-Repair on Cell (세포의 자가 치료 기능을 모사한 디지털 회로에서의 오류 검출 및 복구 알고리즘)

  • Kim, Soke-Hwan
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.19 no.11
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    • pp.2745-2750
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    • 2015
  • Abstract should be placed here In this study, we propose an algorithm of the method of recovering quickly find the location of the error encountered during separate operations in the functional structure of complex digital circuits by mimicking the self-healing function of the cell. By the digital circuit was divided by 9 function block unit of function, proposes a method that It can quickly detect and recover the error position. It was the detection and recovery algorithms for the error location in the digital circuit of a complicated structure and could extended the number of function block for the $3{\times}3$ matrix structure on the dital circuit.

M-13 박테리오파지 기반 신개념 고감도 고선택성 컬러센서

  • Kim, Chun-Tae;Lee, So-Yeong;Kim, Won-Geun;O, Jin-U
    • Proceedings of the Korean Vacuum Society Conference
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    • 2013.08a
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    • pp.294-294
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    • 2013
  • 자연계의 많은 생물들은 의사소통이나 분위기 표현, 위장 등을 하기위해 자신의 색을 바꾸는 것으로 알려져 있으며, 현재 많은 연구자들이 이러한 자연 현상으로부터 영감을 받아 생체모방 구조와 메커니즘을 이용한 바이오센서를 개발하고 있다. 하지만 기존의 컬러센서는 수용체 개발에 있어 복잡한 디자인, 어려운 합성 방법 및 낮은 감도와 저선택성 등의 한계점을 가지고 있다. 이에 본 연구에서 우리는 바이러스(M13-박테리오파지)를 기반으로 한 신개념 고감도 고선택성 컬러센서를 개발하고자 한다. 우리가 개발하고자 하는 컬러센서는 자가 조립방법으로 만들어진 나노 구조체로 형성되어 있으며, 다양한 종류의 화학물질이나 오염물질을 감지할 수 있다. 이 컬러센서는 아주 낮은 농도의 휘발성 유기화합물(volatile organic compounds)을 감지해 색변화를 보였으며, 다양한 독성 물질이나 방향족을 가진 화학 물질을 감지할 수 있었다. 따라서 우리가 개발한 컬러 센서는 국가의 안보나 국민의 건강을 증진시키기에 아주 유용할 것으로 보인다.

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Responses of Artificial Flow-Sensitive Hair for Raider Detection via Bio-Inspiration (침입자 탐지용 인공 유동감지모의 응답 모델링)

  • Park, Byung-Kyu;Lee, Joon-Sik
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.34 no.4
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    • pp.355-364
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    • 2010
  • Filiform hairs that respond to movements of the surrounding medium are the mechanoreceptors commonly found in arthropods and vertebrates. In these creatures, the filiform hairs function as a sensory system for raider detection. Parametric analyses of the motion response of filiform hairs are conducted by using a mathematical model of an artificial flow sensor to understand the possible operating ranges of a microfabricated device. It is found that the length and diameter of the sensory hair are the major parameters that determine the mechanical sensitivities and responses in a mean flow with an oscillating component. By changing the hair length, the angular displacement, velocity, and acceleration could be detected in a wide range of frequencies. Although the torques due to drag and virtual mass are very small, they are also very influential factors on the hair motion. The resonance frequency of the hair decreases as the length and diameter of the hair increase.

Recent Advances on TENG-based Soft Robot Applications (정전 발전 기반 소프트 로봇 응용 최신 기술)

  • Zhengbing, Ding;Dukhyun, Choi
    • Composites Research
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    • v.35 no.6
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    • pp.378-393
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    • 2022
  • As an emerging power generation technology, triboelectric nanogenerators (TENGs) have received increasing attention due to their boundless promise in energy harvesting and self-powered sensing applications. The recent rise of soft robotics has sparked widespread enthusiasm for developing flexible and soft sensors and actuators. TENGs have been regarded as promising power sources for driving actuators and self-powered sensors, providing a unique approach for the development of soft robots with soft sensors and actuators. In this review, TENG-based soft robots with different morphologies and different functions are introduced. Among them, the design of biomimetic soft robots that imitate the structure, surface morphology, material properties, and sensing/generating mechanisms of nature has greatly benefited in improving the performance of TENGs. In addition, various bionic soft robots have been well improved compared to previous driving methods due to the simple structure, self-powering characteristics, and tunable output of TENGs. Furthermore, we provide a comprehensive review of various studies within specific areas of TENG-enabled soft robotics applications. We first explore various recently developed TENG-based soft robots and a comparative analysis of various device structures, surface morphologies, and nature-inspired materials, and the resulting improvements in TENG performance. Various ubiquitous sensing principles and generation mechanisms used in nature and their analogous artificial TENG designs are demonstrated. Finally, biomimetic applications of TENG enabled in tactile displays as well as in wearable devices, artificial electronic skin and other devices are discussed. System designs, challenges and prospects of TENGs-based sensing and actuation devices in the practical application of soft robotics are analyzed.

Performance comparison of Image De-nosing Techniques based on Color Model Transformation (컬러 이미지 변환을 이용한 노이즈 제거 방법 및 성능 비교)

  • Kim, Taeho;Kim, Hakran
    • Journal of Digital Contents Society
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    • v.18 no.8
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    • pp.1641-1648
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    • 2017
  • The main purpose of this paper is to compare the performances of various filters with color images to remove the noise. Furthermore, we suggest a modified de-noising process by the transformation of color model from RGB to another color models, such as HSV and $YC_BC_R$, to improve the quality of de-noising methods encompassing Median, Wiener, and Mean filters. Neither the performance comparison of the de-noising filters with color images nor the converting the color model for better de-noise on the degraded images haven't been performed before. Inspired to make improvements, we conduct experiments with new de-noising process on color images. The result of the experiments is shown that it could assist on certain filters being more reliable techniques.

m-shaper: A Sketch Drawing System for Musical Shape Generation (m-shaper: 음악적 형태 생성을 위한 스케치 드로잉 시스템)

  • Kwon, Doo-Young
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.16 no.2
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    • pp.1381-1387
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    • 2015
  • This paper proposes a sketch drawing system called m-shaper for musical shape generation. Through simple sketch drawing, users can generate musical shape configuration which can be played by a computer. One key ingredient of the process is a unique concept for the interactive musical shape generation that combines shape and sound based on the designers' manual inputs. m-shaper captures the numerical values of drawing characteristics and determines how the musical notes and shapes can be generated. Using a tablet, four sketch movements are captured such as pressure, tilt, rotation and speed. Each point of a shape corresponds to a certain musical note that represents a type of instrument, duration, pitch, and octave. The current m-shaper has been developed as a computational tool for supporting the schematic design process. Designers in m-shaper draw geometric sketches with a musical inspiration and explore possible conceptual forms. They also can control the parameters for results and transform their sketch drawing.

Body Painting Convergence Design Using Grotesque Painting Works (그로테스크 회화 작품을 응용한 바디페인팅 융합 디자인)

  • kwak, ju-young;Kang, Eun-Ju
    • Journal of the Korea Convergence Society
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    • v.10 no.4
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    • pp.209-217
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    • 2019
  • This study examined the concept and characteristics of grotesque painting and its history and presented body painting convergence designs using paintings of each age as basic data on creative and unique body painting design. For the purpose, this study theoretically examined the concepts, characteristics and expressing techniques of grotesque and body painting, analysed images of grotesque paintings in each age and represented convergence body painting based on the results. As a result, it was discovered that paintings including grotesque paintings provided infinite imagination and diverse themes for body painting artists. It means that artistic works can work efficiently for future body painting design. Also, it is expected that they will inspire those who want to study them more academically and in an organized way and body painting will have an independent area in art.

Thermodynamics-Based Weight Encoding Methods for Improving Reliability of Biomolecular Perceptrons (생체분자 퍼셉트론의 신뢰성 향상을 위한 열역학 기반 가중치 코딩 방법)

  • Lim, Hee-Woong;Yoo, Suk-I.;Zhang, Byoung-Tak
    • Journal of KIISE:Software and Applications
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    • v.34 no.12
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    • pp.1056-1064
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    • 2007
  • Biomolecular computing is a new computing paradigm that uses biomolecules such as DNA for information representation and processing. The huge number of molecules in a small volume and the innate massive parallelism inspired a novel computation method, and various computation models and molecular algorithms were developed for problem solving. In the meantime, the use of biomolecules for information processing supports the possibility of DNA computing as an application for biological problems. It has the potential as an analysis tool for biochemical information such as gene expression patterns. In this context, a DNA computing-based model of a biomolecular perceptron has been proposed and the result of its experimental implementation was presented previously. The weight encoding and weighted sum operation, which are the main components of a biomolecular perceptron, are based on the competitive hybridization reactions between the input molecules and weight-encoding probe molecules. However, thermodynamic symmetry in the competitive hybridizations is assumed, so there can be some error in the weight representation depending on the probe species in use. Here we suggest a generalized model of hybridization reactions considering the asymmetric thermodynamics in competitive hybridizations and present a weight encoding method for the reliable implementation of a biomolecular perceptron based on this model. We compare the accuracy of our weight encoding method with that of the previous one via computer simulations and present the condition of probe composition to satisfy the error limit.

Seo Yu-gu's Design Concept for a Rural Residential Landscape (서유구(徐有榘)의 향촌 주거환경 조성에 관한 구상)

  • Shim, Myung Joo
    • Journal of the Korean Institute of Landscape Architecture
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    • v.50 no.2
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    • pp.127-137
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    • 2022
  • In this paper, we have examined Seo Yu-gu's concept of rural home landscaping by reviewing the contents in Wonrim·Ganso in Hyungbipochi. The origin of his concept of rural residential landscaping reflects the Joseon Fengshui perspective following Bokgeo Sayo. Keeping in mind the requirements for living environment based on the Joseon Fengshui perspective, Seo Yu-gu interpreted Jiangjiuyuanji and introduced the components of ideal living that he had obtained from it in ways applicable and suitable to rural homes in Joseon. Jiangjiuyuanji, which contains the natural elements such as mountains, water, fields, and trees, could have been well received by Joseon scholars. As Seo Yu-gu explained in Sangtaekji, it had all the components of Nakto. In sum, constructing the hedges with three layers to promote the safety of rural residents and protect the food sources, utilising water sources for rural homes in various ways, and creating a beautiful courtyard Seokgasan and ponds were Seo Yu-gu's ways of reproducing the requirements for Nakto described in Jiangjiuyuanji such as a safe living environment surrounded by mountains resembling a lotus flower castle, a plentiful water source, and a beautiful natural environment based on the principle of 'Bokgeo Sayo'. In other words, through the content of his writing Wonrim·Ganso, he was articulating his thoughts on how to realise the ideal living conditions described in Jiangjiuyuanji in ways applicable to rural homes in Joseon. In the extended context of Imwon gyeongje ji, such deliberation of Seo Yu-gu shows a glimpse of the goals and practices he pursued through it. The content of Wonrim·Ganso in Hyungbipochi truly manifests Seo Yu-gu's approach to and understanding of Chinese literature. Moreover, his suggestions for application in rural Joseon villages verify the orientation and practical goals of Imwon gyeongje ji as he stated in the preface that 'the book was written specially for Joseon'.