• Journal of the Korean Society of Food Culture
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• v.35 no.6
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• pp.605-612
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• 2020

In this study, 11 plant extracts from Bangladesh were used to evaluate the total phenolic and flavonoid content, in vitro antioxidant activities using 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2-azinobis-(3-ethylbenzthiazolin-6-sulfonic acid) (ABTS), and ferric reducing antioxidant power (FRAP) assay. Also, the inhibitory effect of nitric oxide (NO) production in RAW 264.7 macrophage cell line and the neuroprotective effect on H2O2-induced PC12 cells were tested. Our results revealed that Piper betle L. showed the highest total phenolic content (162.2 mg GAE/g extract) among the 11 plants from Bangladesh. Most plants showed strong radical scavenging effects and ferric reducing antioxidant power. Besides, Piper betle L. protected PC12 neuronal cells against H2O2 related oxidative stress in LPS-induced PC12 cells. Regarding the anti-inflammatory effect, Piper betle L. significantly inhibited NO accumulation in LPS-induced RAW 264.7 cells. Our results provide evidence that Piper betle L. could be useful for the development of functional health foods.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.17 no.2
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• pp.503-514
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• 2013

Mobile Healthcare is a new type of health care services for managing health and life irrespective of time and space by uniting IT and BT. For this service bio-signal measurement using WBAN, and data analysis and monitoring technologies based on mobile devices are essential. Generally, however, mobile application has low compatibility because of the features of mobile platform, we have to redevelop it to support the corresponding platform. In this paper we introduce a Mobile Healthcare System which can function as gateway and monitoring based on hybrid app to create ubiquitous healthcare monitoring system compatible with various mobile devices by overcoming the difference of platforms. The proposed system consists of sensor composition part, monitoring composition part, and server composition part.

• Journal of Dairy Science and Biotechnology
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• v.41 no.2
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• pp.57-66
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• 2023

Majority of the respiratory infectious diseases that are generally prevalent in Korea from autumn to winter are caused by viruses such as respiratory syncytial virus and influenza A virus. Therefore, there is rapidly rising interest in determining the antiviral effects of probiotics against respiratory viruses and elucidating the probable mechanism behind it. Various human clinical trials as well as animal experiments have shown that some probiotics potentially have antiviral activity based on their immunomodulatory effect. Hence, this review describes in detail the various possibilities of using probiotics as antiviral agents against respiratory viruses and their potential effects. Also, it provides basic data regarding the availability of different probiotics relevant for their production by dairy and food industries.

• Journal of Marine Bioscience and Biotechnology
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• v.15 no.2
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• pp.33-40
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• 2023

This study aimed to investigate the immunomodulatory function of Pyropia yezoensis hydrothermal (water) extract (PYWE) in comparison to the group treated only with lipopolysaccharides (LPS) in RAW264.7 cells. LPS is known to be an inflammatory mediator that activates macrophages, leading to the secretion of nitric oxide (NO), inducible nitric oxide synthase (iNOS), tumor necrosis factor-α (TNF-α), and interleukin-6 (IL-6) as defense responses. Through enzyme-linked immunoassay and western blot analyses, it was observed that PYWE increased the expression levels of NO, iNOS, TNF-α, and IL-6 in RAW264.7 cells in a dose-dependent manner, although to a lesser extent compared with the group treated with LPS alone. In addition, the study examined the mitogen-activated protein kinases (MAPKs) pathway, which regulates various cellular activities, including gene expression, mitosis, cell differentiation, transformation, survival, and death. The western blot analysis confirmed that PYWE also regulated the MAPKs pathway. Furthermore, the expression levels of immunomodulatory-related factors increased in the group treated with PYWE compared with the control group. Even though the effects of PYWE were usually less strong than those of LPS, the effects of PYWE increased with increasing doses compared to the control group. This suggests that PYWE could be used to control the immune system.

• Journal of Korea Society of Industrial Information Systems
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• v.26 no.4
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• pp.1-9
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• 2021

This study was to investigate the types of emergencies transported by the Southwestern Coast Guard, the need for telemedicine guidance, and the perception and attitude of smart glasses as a communication method targeting 31 coast guards. A relatively high frequency and training requirement were confirmed for bleeding, abrasion, and abdominal pain. The demand for telemedicine guidance on medication and triage was higher, and the perceived usefulness and attitude scores for the use of smart glasses were 3.76±0.61 and 3.64±0.45, respectively. A moderate correlation between perceived usefulness and attitude toward smart glasses was confirmed (r=.630, p<.01). With the development of technology, it is time to actively introduce new devices such as smart glasses.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.15 no.4
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• pp.965-972
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• 2011

As an aged population has increased in Korea, the number of patients with chronic disease has soared up as well. The rapid increase of the chronic disease triggers a need of new paradigm of healthcare. In terms of data transmission of healthcare system, a use of data-transmission protocol based on bluetooth could be dismal in application of healthcare due to its postponement of connection. On the contrary, WPAN is evaluated to be proper to support the application of healthcare in restricted geographic areas. In addition, the bluetooth, a base of the current wireless network, doesn't support a special mechanism to cope up with emergent patients because of its delayed connection among devices. Against this backdrop, this study aims to design an integrated interface of multi bio-sensing and suggest a measuring and monitering system for the patients with chronic illnesses by using Zigbee of WPAN as a sufficient bandwidth is anticipated owing to frequent deliveries of complicated biological signals.

• Journal of Dairy Science and Biotechnology
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• v.41 no.4
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• pp.179-190
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• 2023

Currently, various probiotics are being used to improve the nutrition of companion animals. They are widely sold as additives in companion animal foods because of the numerous gastrointestinal and immune health benefits for dogs and cats. Therefore, extensive research is being conducted to improve quality and safety during manufacturing and to extend the shelf life of companion animal foods by adding probiotics. The manufacturing process must be conducted such that the characteristics and efficacy of probiotics added to food are optimally beneficial for companion animals. Therefore, this review aims to address the overall characteristics of the probiotic strains used and to examine the various methods through which probiotics are added to companion animal foods.

• Journal of Dairy Science and Biotechnology
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• v.41 no.3
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• pp.87-102
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• 2023

Globally, acute gastroenteritis is responsible for two million pediatric deaths. In particular, viral gastroenteritis is the most common cause of acute diarrhea, and most children aged <5 years are infected at least once. The common symptoms include profuse watery diarrhea, vomiting, abdominal pain, and fever. Viral gastroenteritis is generally caused by rotavirus, norovirus, astrovirus, and adenovirus. Recently, probiotics use has increased rapidly worldwide due to its inhibitory effect against viral gastroenteritis. In addition, probiotics are known to have anti-inflammatory and anti-allergic effects and enhance immunity without any side effects. Therefore, this review focuses on the anti-viral effects of probiotics on viral gastroenteritis. Furthermore, this review would provide basic data that could be used for developing new products that have improved functionality by addition of probiotics to milk and dairy food.

• 한국IT서비스학회:학술대회논문집
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• 2009.11a
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• pp.467-472
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• 2009

USN은 하드웨어와 유 무선 통신기술이 서로 네트워크로 연결되어 사물이나 환경의 정보를 획득하고 가공해 유용한 정보로 창출하는 것을 목표로 하고 있으며, 그 중 u-Healthcare는 의료 서비스 질 향상이라는 필요성에 의해 이슈가 되고 있다. 본 논문에서는 이 기종 센서 네트워크에서 획득한 데이터를 추상화하고 상황에 맞는 서비스를 제공하는 지능형 미들웨어를 설계하였다. 설계된 미들웨어를 사회적 이슈가 되고 있는 IT의료 분야에 적용해서 헬스 케어 모니터링 시스템을 구현했다. 센서를 통해 온도, 습도, 조도, 심박 수, 체온을 측정해서 실시간으로 관리하고 모니터링 하는 기능을 지원한다. 또한, 실시간으로 전달되는 바이오 정보를 통합 관리하는 부분에 초점을 맞추어 연구를 진행했다.

• Annual Conference of KIPS
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• 2023.11a
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• pp.563-565
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• 2023

Acupuncture and acupressure apply needles or pressure to anatomical points for therapeutic benefit. The over 350 mapped acupuncture points in the human body can each treat various conditions, but anatomical variations make precisely locating these acupoints difficult. We propose a computer vision technique using the real-time hand and face tracking capabilities of the MediaPipe framework to identify acupoint locations. Our model detects anatomical facial and hand landmarks, and then maps these to corresponding acupoint regions. In summary, our proposed model facilitates precise acupoint localization for self-treatment and enhances practitioners' abilities to deliver targeted acupuncture and acupressure therapies.