• Korean Journal of Plant Resources
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• v.36 no.5
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• pp.446-454
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• 2023

This study aimed to assess the potential use of Paeonia lactiflora Pall. seed cake (PSC). The extraction yield of the PSC extract ranged from 22% to 45%, depending on the extraction solvent used. The PSC extract showed significantly higher levels of total polyphenols and flavonoids contents, and radical scavenging compared to the P. lactiflora seed oil (PSO) extract. The antibacterial activity of the PSC extract was superior to that of the positive control and remained effective for up to 48 hours. Furthermore, when the PSC extract was applied, it significantly reduced the inflammatory response induced by LPS, demonstrating the anti-inflammatory activity of PSC. This study confirmed the effective bioactivity not only in PSO, but also in the PSC extract, highlighting the potential of PSC as a bio-health ingredient.

• Applied Chemistry for Engineering
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• v.35 no.2
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• pp.122-127
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• 2024

Cosmetic preservatives are an important class of ingredients in terms of ensuring sustainable use and providing customer satisfaction. Recently, a great deal of interest has been drawn to the production and use of toxic-free, naturally derived preservatives. In this work, a new naturally derived preservative (laurimino bispropanediol, LB) was developed to replace the most widely used diol preservatives, such as 1,2-hexanediol or 1,2-octanediol. The basic properties of the obtained preservative were measured, and the solution behavior of the preservative in an aqueous medium was examined. The feasibility of micelle formation in the preservative solution was investigated using the fluorescence (FL) based pyrene method. Micelle formation was feasible owing to the relatively long hydrophobic chains and increased hydroxyl groups in the preservative molecules. The emulsification capability of the preservative was assessed using the Rosano and Kimura method, showing that the preservative possessed emulsifying capability in an organic solvent (benzene) and soy bean oil. In addition, the dispersion stability of cosmetic formulations, including the new LB preservatives such as essence and lotion, was demonstrated by comparing the light transmittance of the formulations. This article provides important information for future research regarding the synthesis and practical applications of new toxic-free naturally derived preservatives.

• Herbal Formula Science
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• v.32 no.3
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• pp.297-310
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• 2024

Objective : This study was conducted to investigate the anti-inflammatory and laxative effects of Polycan in TNF-α-treated HT-29 intestinal epithelial cells and loperamide-induced constipation in vivo models, respectively. Methods : To evaluate the anti-inflammatory effects of Polycan, HT-29 cells were treated with TNF-α in the presence or absence of Polycan. IL-8 production was measured by enzyme-linked immunosorbent assay (ELISA). MAPK phosphorylation, nuclear translocation of NF-κB, and phosphorylation of IκB were assessed by Western blot analysis. To investigate the laxative effects of Polycan, 6-week-old SD rats (8 female rats per group) were orally administered Polycan or Chicory Fiber as a positive control for 4 weeks, and constipation was induced with loperamide treatment for 10 days before sacrifice. One day before sacrifice, a charcoal meal was administered to evaluate intestinal transit times. The periodically collected feces were used to assess the number of fecal pellets and fecal water content. Results : Polycan inhibited TNF-α-induced IL-8 expression in dose-dependent manner. Furthermore, Polycan suppressed TNF-α-induced phosphorylation of MAPKs (ERK1/2, p38 and JNK), degradation of Iκ-Bα and nuclear translocation of NF-κB. In an in vivo constipation model, the number of fecal pellets per food intake was significantly increased in rats administered with Polycan, both 1 day and 7 days after loperamide treatment. The water content of fecal pellets was restored in the Polycan groups starting 7 days after loperamide treatment. In addition, Polycan intake significantly enhanced the gastrointestinal transit ratio of a charcoal meal but reduced the number of intestinal fecal pellets. Conclusions : These results suggest that Polycan suppressed TNF-α-induced inflammation by blocking both the MAPK and NF-κB pathways in HT-29 cells. Additionally, in a loperamide-induced constipation model, Polycan showed clear laxative effects by increasing the number of fecal pellets, fecal water content, and intestinal transit ratio of a charcoal meal.

• Journal of Practical Engineering Education
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• v.16 no.4
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• pp.599-609
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• 2024

The government has introduced the Regional Innovation System (RIS) to establish regional innovation platforms, leading to the creation of the Bio-PRIDE shared university in the Chungbuk region, centered around the bio-health industry. The purpose of this study is to analyze the educational service quality of the Bio-PRIDE shared university through a qualitative approach. To achieve this, in-depth exploration of the experiences of students participating in the Bio-PRIDE shared university was conducted using Focus Group Interviews (FGI) and telephone interviews. The study identified three main findings: 1) Motivations for student participation included recommendations and support from professors, economic benefits and scholarships, the flexibility and convenience of remote learning, and the appeal of new learning experiences and challenges. 2) Experiences during participation revealed themes such as the effectiveness and challenges of remote classes, the value of providing up-to-date technology and content, student engagement and commitment, and communication and support from faculty. 3) The impact of participation after completing the program highlighted the importance of innovative learning experiences and expanded choices, the significance of information accessibility and learning support, the need for improved promotion and awareness of the shared university, and the necessity for administrative support and communication. In conclusion, the Bio-PRIDE shared university has successfully implemented educational innovation, offering students new learning experiences and contributing to the broadening of their academic perspectives. This study will serve as a foundational resource for improving the educational service quality and ensuring the successful operation of the Bio-PRIDE shared university in the future.

• The Journal of the Korea Contents Association
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• v.8 no.10
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• pp.1-10
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• 2008

The traditional barcode based medicine logistics system have the problems such as loss, management error, online track, public information due to the hand-operated logistic process. Otherwise, quick response allows that the company observe the requests consistently and design medicine and establish manufacture schedule rapidly so that they could prohibit the product stocked. In this paper, we analyzed how to process medicine circulation logistics and information steps practically and proposed the RFID based medicine logistics system for the quick response in hospital. The proposed method provided the medical history tracing service, the traditional system connection, the efficiency logistic service, and the narcotic specified management service using the medicine logistics information from RFID tag. Accordingly, the satisfaction and the productivity will be improved the efficient medicine logistics by reducing the loss as well as the management error.

• Journal of Information Technology Services
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• v.19 no.2
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• pp.23-35
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• 2020

The development of digital technology is changing the paradigm of the healthcare industry to preventive and consumer-oriented. The combination of the ICT industry and the bio-healthcare industry is emerging as a core industry in the era of the Fourth Industrial Revolution. The Korean government has also selected the bio-healthcare industry as one of the three key future development industries. In May, the government announced its bio-health industry innovation strategy and set a goal of 300,000 employees. Therefore, analyzing the effects of employment on the related industries of the digital bio-healthcare industry is very important for the establishment of future industrial and technology development policies. The research method restructures the integrated classification of 32 industries into 34, including the digital bio-healthcare industry, using the classification criteria of the government and professional institutions, and then reorganizes the digital bio-healthcare industry into eight industries classified as one industry group. The analysis data was taken from the Bank of Korea's 2019 data. Various trigger coefficients and ripple effects coefficients were rewritten using the analysis method of the Input-output Statistics. The analysis of the results compares the employment-induced effects of the digital bio-healthcare industry and the ripple effects of related industries in production, investment and value-added. In addition, in terms of investment effect, the effects of in-house and related industries were compared. It is hoped that the results of this study will be used to establish employment and industrial policies.

• The Journal of the Korea institute of electronic communication sciences
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• v.8 no.10
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• pp.1485-1490
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• 2013

The demonstration project of the electrical grid for Smart grid is progressed, the smart digital appliances AV technology, Smart home energy management technology charging the management function of complex energy for the automation management of air conditioning and heating, humidity and air, the health care technology charging the design of housing for the elderly and disabled and the measurement of individual bio information, and the Smart home security technology dealing with the biometric security and motion sensors, etc. have been studied. The power monitoring terminal which uses a variety of wired and wireless networks and protocol is the target additionally to be considered in addition to the security vulnerabilities that was occurred in the existing terminal. In this research paper, the author analyzes the cryptographic techniques corresponding to the smart meter occurred by the problems that are exposed on the outside which are vulnerable to physical attacks, and intends to propose the design of the security systems for the Smart meter terminal being able to maximize the efficiency of the terminal.

• Journal of the Korean Applied Science and Technology
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• v.38 no.5
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• pp.1229-1240
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• 2021

Ginkgo (Ginkgo biloba L.) seeds, called 'Baekqwa', were extracted from 70% ethanol to investigate the whitening effect and to confirm the application potential as a cosmetic material. Ginkgo seed ethanol extracts (GBE) were treated with B16F10 melanoma cells, and melanin contents and tyrosinase, which is the main enzyme concerning the synthesis process of melanin, inhibitory activity were confirmed. As a result, there were inhibited in a concentration-dependent manner, and GBE also significantly reduced the protein expression and mRNA levels of tyrosinase, tyrosinase-related protein-1, -2 (TRP-1, -2), and their upstream transcription factor, microphthalmia-associated transcription factor (MITF). These results suggest that GBE could be used as an effective whitening agent that has an inhibitory effect on melanin production by regulating the expression and degradation of MITF in melanocytes.

• Journal of the Korea Convergence Society
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• v.12 no.12
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• pp.551-562
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• 2021

This study aimed to identify the effect of resilience and positive psychological capital on hospital nurses' professional quality of life. A cross-sectional survey design was utilized to investigate 221 general hospital nurses from June 1 to 30, 2021. Professional quality of life (ProQOL), which is conceptualized with three sub-dimensions (compassion satisfaction, burnout, and secondary traumatic stress), resilience, and positive psychological capital variables were measured. There was a positive relationship between compassion satisfaction and resilience, positive psychological capital, and a negative relationship among burnout, secondary traumatic stress, and the other variables in this study. The main factors influencing compassion satisfaction were resilience, and positive psychological capital, which explained about 47% of compassion satisfaction. Burnout was influenced by resilience, positive psychological capital, and work pattern, and these variables explained about 37% of burnout. Notably, it was found that resilience was the most crucial factor in nurses' compassion satisfaction, and positive psychological capital was the most crucial factor in nurses' burnout. Thus, it is suggested to develop and verify the effectiveness of a resilience improvement program and positive psychological intervention program to strengthen the internal resources of hospital nurses.

• Journal of IKEEE
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• v.25 no.1
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• pp.206-211
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• 2021

This paper proposes a Self-Reset Zero-Current Switching (ZCS) Circuit for thermoelectric energy harvesting. The Self-Reset ZCS circuit minimizes the operating current consumed by the voltage comparator, thereby reduces the power consumption of the energy harvesting circuit and improves the energy conversion efficiency by adding the self-reset function to the comparator. The Self-Reset ZCS circuit shows 3.4% of improvement in energy efficiency compared to the energy harvesting system with the conventional analog comparator ZCS for the output/input voltage ratio of 5.5 as a result of circuit simulation. The proposed circuit is useful for improving the performance of the wearable and bio-health-related harvesting circuits, where low-power and energy-efficient thermoelectric energy harvesting is needed.