• Title/Summary/Keyword: 미소

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Cytokinesis-blocked micronuclei in the human peripheral lymphocytes following low dose γ-rays irradiation (저선량의 감마선 피폭된 사람 말초 임파구의 미소핵을 이용한 방사선 생물학적 피폭선량 측정법 연구)

  • Kim, Tae-hwan
    • Korean Journal of Veterinary Research
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    • v.41 no.1
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    • pp.99-104
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    • 2001
  • To determine if micronucleus (MN) assay could be used to predict the absorbed dose of victims after accidental radiation exposure, we carried out to assess the absorbed dose depending on the numerical changes of MN in human peripheral blood lymphocytes after $^{60}Co\;{\gamma}-rays$ exposure in the range of 0.25 to 1 Gy, respectively. The MNs were observed at very low doses, and the numerical changes according to doses. Satisfactory dose-effect calibration curve is observed after low dose irradiation of human lymphocytes in vitro. When plotting on a linear scale against radiation dose, the line of best fit was $Y=(0.02{\pm}0.0009)+(0.033{\pm}0.010)D+(0.012{\pm}0.012)D^2$. The dose-response curve for MN induction immediately after irradiation was linear-quadratic and has a significant relationship between the frequencies of MN and dose. These data show a trend towards increase of the numbers of MN with increasing dose. The number of MN in lymphocytes that were observed in the control group is $0.1610{\pm}0.0093/cell$. Accordingly, MN assay in human peripheral lymphocytes could be a useful in viva model for studying radio-protective drug sensitivity or screening test, microdosimertic indicator and radiation-induced target organ injury. Since MN assay is simple, rapid and reproducible, it will also be a biodosimetric indicator for individual dose assessment after accidental exposure.

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Acoustic Emission Property and Damage Estimation of Rock Due to Cyclic Loading (반복하중 시험 시 발생하는 암석의 미소파괴음 특성과 손상도 평가)

  • Jang Hyun-Shic;Ma Yon-Sil;Jang Bo-An
    • The Journal of Engineering Geology
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    • v.16 no.3 s.49
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    • pp.235-244
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    • 2006
  • Granite cores were sampled within Korea Atomic Energy Research Institute and cyclic loadings up to 1550 cycles were applied. Microcrack development in samples due to cyclic loading was estimated using Acoustic Emission(AE) method. AE showed two different types depending on numbers of cycle. Type 1 appeared at low cycles and had low energy and diverse frequencies, while type 2 appeared at high cycles and had high energy and uniform frequency. AE property of type 1 indicates voids and pre-existing microcracks in samples may close or propagate up to certain length. Microcracks may be sheared or closed during loading and are recovered from shear or opened during unloading when AE of type 2 were measured. P wave velocities and Felicity ratios were measured at 50, 150, 350, 750, 1550 cycles. P wave velocities were almost the same regardless of number of cycles applied. However, Felicity ratios were much lower than 0.9, indicating that microcracks were developed within samples. This result indicates that Felicity ratio is a better tool than P wave velocity to estimate the damage of rock.

Preparation of Biopolymer coated Magnetite And Magnetic Biopolymer Microsphere Particles for Medical Application (의학적 응용을 위한 생체 고분자로 피복 된 자성 나노 입자와 미소구체의 제조)

  • Ko, Sang-Gil;Cho, Jun-Hee;Ahn, Yang-kyu;Song, Ki-Chang;Choi, Eun-Jung
    • Journal of the Korean Magnetics Society
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    • v.16 no.4
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    • pp.221-227
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    • 2006
  • We have synthesized uniform nanometer sized magnetite particles using chemical coprecipitation technique through a sonochemical method with surfactant such as oleic acid. Magnetite phase nanoparticles could be observed from X-ray diffraction. Magnetite nanoparticles is surface phase morphology and biopolymer-microspheres for Application Medical. Magnetite nanoparticles coated biopolymer. Atomic Force Microscope (AFM) was used to image the coated nanoparticles. Magnetic colloid suspensions containing particles with sodium oleate, chitosan and $\beta$-glucan have been prepared. The morphology of the magnetic biopolymer microsphere particles were characterized using optical microscope. Magnetic hysteresis measurement were performed using a superconducting quantum interference device (SQUID) magnetometer at room temperature to investigate the magnetic properties of the biopolymer microspheres and magnetite coated biopolymer including magnetite nanoparticles. Magnetic Resonance (MR) imaging was used to investigate biopolymer coated nanoparticles and biopolymer microspheres.

Evaluation for Fundamental Periods of Domestic Rockfill Dams with Micro-earthquake Records (미소지진 계측기록을 활용한 국내 사력댐 고유주기 산정방법)

  • Ha, Iksoo
    • Journal of the Korean GEO-environmental Society
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    • v.12 no.6
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    • pp.53-60
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    • 2011
  • The purpose of this study is to propose a method that can reliably evaluate the fundamental period of a rockfill dam using the micro-earthquake records, which were obtained at the domestic dam sites. For total 20 micro-earthquake records obtained at 7 domestic rockfill dam sites against 6 earthquake events which recently occurred, the fundamental periods of seven rockfill dams were evaluated by two kinds of methods; one is a method using acceleration amplification ratio and the other is a method using acceleration response spectrum ratio. Applicability of each method to evaluation of fundamental periods of domestic rockfill dams was examined. In the moderate seismicity region like our country, the method using acceleration response spectrum ratio, which could evaluate the fundamental period of the rockfill dam using the ratio between the response spectrum for acceleration observed at the dam crest and that observed at the dam base or abutment, proved to be reliable and was proposed in this study. From the results of analyses, it was found that the proposed method could consistently evaluate the fundamental period of the rockfill dam and the results obtained by the proposed method were very similar to the results by the existing method which was proposed from the analysis for the earthquake records observed at Japanese dam sites.

Effects of a Dielectric Multilayer Mirror on the Lighting Efficiency of Organic Light-Emitting Diodes Studied by Optical Simulation (유전체 다층 거울이 유기발광다이오드의 광효율 향상에 미치는 영향에 관한 광학 시뮬레이션 연구)

  • Lee, Sung-Jun;Ko, Jae-Hyeon
    • Korean Journal of Optics and Photonics
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    • v.26 no.3
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    • pp.139-146
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    • 2015
  • The effects of a dielectric multilayer mirror on the efficiency of organic light-emitting diodes (OLEDs) were investigated by using optical simulation. Adoption of a dielectric mirror consisting of alternating SiN and $SiO_2$ layers narrowed the emission spectrum due to the microcavity effect, and increased the outcoupling efficiency by a few percent. The layer thicknesses of the dielectric mirror were adjusted to change the wavelength of the resonance mode, which may be used to increase the color purity.

Planarization & Polishing of single crystal Si layer by Chemical Mechanical Polishing (화학적 기계 연마(CMP)에 의한 단결정 실리콘 층의 평탄 경면화에 관한 연구)

  • 이재춘;홍진균;유학도
    • Journal of the Korean Vacuum Society
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    • v.10 no.3
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    • pp.361-367
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    • 2001
  • Recently, Chemical Mechanical Polishing(CMP) has become a leading planarization technique as a method for silicon wafer planarization that can meet the more stringent lithographic requirement of planarity for the future submicron device manufacturing. The SOI(Silicon On Insulator) wafer has received considerable attention as bulk-alternative wafer to improve the performance of semiconductor devices. In this paper, the objective of study is to investigate Material Removal Rate(MRR) and surface micro-roughness effects of slurry and pad in the CMP process. When particle size of slurry is increased, Material Removal rate increase. Surface micro-roughness is greater influenced by pad than by particle size of slurry. As a result of AM measurement, surface micro-roughness was improved from 27 $\AA$ Rms to 0.64 $\AA$Rms.

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An Anisotropic Hardening Elasto-Plastic Constitutive Model for the Behavior at Small-to-Large Strain Conditions (미소변형률 및 대변형률 조건의 거동에 대한 비등방경화 탄소성 구성모델)

  • 오세붕;권기철;정순용;김동수
    • Journal of the Korean Geotechnical Society
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    • v.16 no.1
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    • pp.65-73
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    • 2000
  • An elasto-plastic constitutive model was proposed, in which the behavior at small-to-large strain level can be modeled. The proposed model is based on the anisotropic hardening description with the generalization of isotropic hardening rule and the total stress concept. From a mathematical approach it was proved that the model includes the previous successful models. The model was verified by a series of resonant column tests, torsional shear tests and triaxial tests, and the proposed model predicted small-to-large strain behavior more consistently and accurately than the hyperbolic model and the Ramberg-Osgood model for a weathered granitic soil. In addition, the nonlinearity under small strain condition was predicted appropriately for the torsional shear test results.

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Behavior of Fatigue Crack Propagation of Micro-Hole and Micro-Slit Specimensns - For High-Frequency Heat Treantment Specimens - (微小圓孔 및 微小슬릿材의 疲勞크랙 傳播擧動)

  • 송삼홍;윤명진
    • Transactions of the Korean Society of Mechanical Engineers
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    • v.10 no.1
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    • pp.78-85
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    • 1986
  • This study has been made to investigate Behavior of the fatigue crack propagation for the purpose of taking into consideration the fatigue behavior Which initiate and propagate in tip of defect of the defected specimens, Which Contain the micro-hole or micro-slit. Especially, the specimens have been conducted with high-freguency heat treatment of 850.deg. C, 1050.deg. C to consider strength elevation of defected specimens. The results of this study are as follow; (1) The case of the same in the length of crack, the fatigue crack propagation rate of the micro-slit is always faster than that of micre-hole. But, the first step of the fatigue crack propagation it is not always so. (2) Fatigue crack propagation rate of specimens with micro-slit or micro-hole which have been treated with high-frequency heat treatment satisfy the following formula between the fatigue crack propagation rate and nominal stress; dl/dN .var..sigma.$^{m}$ *l$^{n}$ .

Effect of Ground Vibration on Surface Structures and Human Environments -Application of Blasting Vibration to Induced Seismicity in EGS Hydraulic Stimulation- (지반진동이 지상구조물 및 환경에 미치는 영향평가 -발파진동 사례를 통한 EGS 수리자극에의 활용-)

  • Lee, Chung-In;Min, Ki-Bok
    • Tunnel and Underground Space
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    • v.23 no.6
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    • pp.521-537
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    • 2013
  • While microseismicity induced by hydraulic stimulation carried out for EGS is useful means in estimating the range of permeability increase, it also affect surface structures and environments. In order to establish a mitigation plan for microseismicity triggered by hydraulic stimulation, we reviewed world-wide guidelines on the impact of ground vibration on the surface structure and human environment by blasting. Case studies from Europe and USA on the microseismicity by hydraulic stimulation are presented and suggestions are made for the guidelines on ground vibration by hydraulic stimulation for the ongoing Pohang EGS project.

A Study on Application of Fractal Dimension in Analysis of Damage Mechanics in Rock (암반의 손상역학 해석에 있어서 Fractal차원의 적용에 관한 연구)

  • 정교철;정영기
    • The Journal of Engineering Geology
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    • v.4 no.2
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    • pp.139-151
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    • 1994
  • Rocks are composed of the discrete elements of microstructures such as different grains and microcracks. The studies of these microstructures are of increasing interest in engineering geology and civil engineering related to construction of a deep under-ground space. Accordingly, instead of a simplified continuum approach, discrete structural elements and mechanical properties of various grains must be accounted. But it is difficult to analyse crack and discontinuity surfaces in Euclidean geometry. So, Mandelbrot( 1983) developed fractal theory to manage irregular body in nature. In this study, geometrical properties of microstructures to estimate a relation between crack propagation and stress were calculated. Then it is shown that fractal theory can be applied to research real mechanical behavior of rocks.

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