• Title/Summary/Keyword: 미세단층 촬영

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Polarization-sensitive Optical Coherence Tomography Imaging of Pleural Reaction Caused by Talc in an ex vivo Rabbit Model (생체 외 토끼 모델에서의 탈크에 의해 유발되는 흉막 반응의 편광 민감 광 결맞음 단층촬영 이미징)

  • Park, Jung-Eun;Xin, Zhou;Oak, Chulho;Kim, Sungwon;Lee, Haeyoung;Park, Eun-Kee;Jung, Minjung;Kwon, Daa Young;Tang, Shuo;Ahn, Yeh-Chan
    • Korean Journal of Optics and Photonics
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    • v.31 no.1
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    • pp.1-6
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    • 2020
  • The chest wall, an organ directly affected by environmental particles through respiration, consists of ribs, a pleural layer and intercostal muscles. To diagnose early and treat disease in this body part, it is important to visualize the details of the chest wall, but the structure of the pleural layer cannot be seen by chest computed tomography or ultrasound. On the other hand, optical coherence tomography (OCT), with a high spatial resolution, is suited to observe pleural-layer response to talc, one of the fine materials. However, intensity-based OCT is weak in providing information to distinguish the detailed structure of the chest wall, and cannot distinguish the reaction of the pleural layer from the change in the muscle by the talc. Polarization-sensitive OCT (PS-OCT) takes advantage of the fact that specific tissues like muscle, which have optical birefringence, change the backscattered light's polarization state. Moreover, the birefringence of muscle associated with the arrangement of myofilaments indicates the muscle's condition, by measuring retardation change. The PS-OCT image is interpreted from three major perspectives for talc-exposure chest-wall imaging: a thickened pleural layer, a separation between pleural layer and muscle, and a phase-retardation measurement around lesions. In this paper, a rabbit chest wall after talc pleurodesis is investigated by PS-OCT. The PS-OCT images visualize the pleural layer and muscle, respectively, and this system shows different birefringence of normal and damaged lesions. Also, an analyisis based on phase-retardation slope supports results from the PS-OCT image and histology.

Detecting and Tracking Changes of Mechanical Characteristics of the Trabecular and Cortical Bone in the Lumbar Vertebrae of an OVX Rat - Use of In-Vivo Micro-CT and Micro-FE Analysis - (난소 절제술을 시행한 흰쥐 등뼈의 해면골과 피질골의 구조적 특성 추적관찰 및 기계적 특성 분석 - 생체 내 미세단층촬영 시스템과 미세 유한요소법 적용 -)

  • Ko, Chang-Yong;Woo, Dae-Gon;Lee, Tae-Woo;Lee, Beob-Yi;Tack, Gye-Rae;Kim, Han-Sung
    • Journal of the Korean Society for Precision Engineering
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    • v.24 no.1 s.190
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    • pp.110-117
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    • 2007
  • This study investigated changes of mechanical characteristics of the trabecular and cortical bone in the lumbar vertebrae of the ovariectomised (OVX) rat. In previous researches, there were many studies for morphology of osteoporotic bones based on Micro-Computed Tomography (Micro-CT). However, there were few studies for detecting and tracking changes of mechanical characteristics of the trabecular and cortical bone in the lumbar vertebrae of the OVX rat. For this study, the 4th lumbar of the OVX rat (female Sprague-Dawley) was utilized as a specimen. An OVX rat was scanned at week 0 (just before surgery), at week 4, and week 8 after surgery. Micro-finite element (${\mu}-FE$) analysis was used to investigate mechanical characteristics of the trabecular and cortical bone in the lumbar vertebrae for an OVX rat. When the OVX rat (at week 8) was compared with the OVX rat (at week 0), the structural modulus of cortical and trabecualr bone was decreased by 52% and 99%, respectively. This study showed the change of mechanical characteristics of cortical bone as well as trabecular bone of an OVX rat. Detecting and tracking changes of mechanical characteristics could greatly contribute to an experiment test for the trabecular and cortical bone in the lumbar vertebrae of an OVX rat by using In-vivo Micro-CT.

Variation of the Physical-microstructural Properties of Sandstone and Shale Caused by CO2 Reaction in High Pressure Condition (고압 이산화탄소 반응에 의한 사암과 셰일의 물리적-미세구조적 변화)

  • Park, Jihwan;Son, Jin;Park, Hyeong-Dong
    • Tunnel and Underground Space
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    • v.26 no.4
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    • pp.293-303
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    • 2016
  • Underground $CO_2$ storage technology is one of the most effective methods to reduce atmospheric $CO_2$. In this study, $CO_2$ storage condition was simulated in the laboratory. Sandstone and shale specimens were saturated in 1M NaCl and were reacted at $45^{\circ}C$, 10 atm for 4 weeks. The physical and microstructural properties of rock specimens were measured. Variations on physical properties of shale specimens were bigger than those of sandstone specimens, such as volume, density, elastic wave velocity, Poisson's ratio and Young's modulus. Microstructure were analyzed using X-ray computed tomography. Total number of pores were decreased, and average volume, average area and average equivalent diameter of each pore were changed after $CO_2$ reaction. Swelling and leakage of clay mineral caused by $CO_2$-mineral reaction were the reason of changes. The results of this study can be applied to predict the physical and microstructural changes in underground $CO_2$ storage condition.

3-D OCT Image Reconstruction for Precision Analysis of Rat Eye and Human Molar (쥐 눈과 인간 치아의 정밀한 단층정보 분석을 위한 OCT 3-D 영상 재구성)

  • Jeon, Ji-Hye;Na, Ji-Hoon;Yang, Yoon-Gi;Lee, Byeong-Ha;Lee, Chang-Su
    • The KIPS Transactions:PartB
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    • v.14B no.6
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    • pp.423-430
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    • 2007
  • Optical coherence tomography(OCT) is a high resolution imaging system which can image the cross section of microscopic organs in a living tissue with about $1{\mu}m$ resolution. In this paper, we implement OCT system and acquire 2-D images of rat eye and human molar samples especially in the field of opthalmology and dentistry. In terms of 2-D images, we reconstruct 3-D OCT images which give us another inner structural information of target objects. OPEN-GL reduces the 3-D processing time 10 times less than MATLAB.

THE EFFECTS OF DIETARY CONSISTENCY ON THE TRABECULAR BONE ARCHITECTURE IN GROWING MOUSE MANDIBULAR CONDYLE : A STUDY USING MICRO-CONFUTED TOMOGRAPHY (성장 중인 쥐에서 음식물의 경도가 하악 과두의 해면골에 미치는 영향 : 미세전산화 단층촬영을 이용한 연구)

  • Youn, Seok-Hee;Lee, Sang-Dae;Kim, Jung-Wook;Lee, Sang-Hoon;Hahn, Se-Hyun;Kim, Chong-Chul
    • Journal of the korean academy of Pediatric Dentistry
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    • v.31 no.2
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    • pp.228-235
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    • 2004
  • The development and proliferation of the mandibular condyle can be altered by changes in the biomechanical environment of the temporomandibular joint. The biomechanical loads were varied by feeding diets of different consistencies. The purpose of the present study was to determine whether changes of masticatory forces by feeding a soft diet can alter the trabecular bone morphology of the growing mouse mandibular condyle, by means of micro-computed tomography. Thirty-six female, 21 days old, C57BL/6 mice were randomly divided into two groups. Mice in the hard-diet control group were fed standard hard rodent pellets for 8 weeks. The soft-diet group mice were given soft ground diets for 8 weeks and their lower incisors were shortened by cutting with a wire cutter twice a week to reduce incision. After 8 weeks all animals were killed after they were weighed. Following sacrifice, the right mandibular condyle was removed. High spatial resolution tomography was done with a Skyscan Micro-CT 1072. Cross-sections were scanned and three-dimensional images were reconstructed from 2D sections. Morphometric and nonmetric parameters such as bone volume(BV), bone surface(BS), total volume(TV), bone volume fraction(BV/TV), surface to volume ratio(BS/BV), trabecular thickness(Tb. Th.), structure model index(SMI) and degree of anisotropy(DA) were directly determined by means of the software package at the micro-CT system. From directly determined indices the trabecular number(Tb. N.) and trabecular separation(Tb. Sp.) were calculated according to parallel plate model of Parfitt et al.. After micro-tomographic imaging, the samples were decalcified, dehydrated, embedded and sectioned for histological observation. The results were as follow: 1. The bone volume fraction, trabecular thickness(Tb. Th.) and trabecular number(Tb. N.) were significantly decreased in the soft-diet group compared with that of the control group (p<0.05). 2. The trabecular separation(Tb. Sp.) was significantly increased in the soft-diet group(p<0.05). 3. There was no significant differences in the surface to volume ratio(BS/BV), structure model index(SMI) and degree of anisotropy(DA) between the soft-diet group and hard-diet control group (p>0.05). 4. Histological sections showed that the thickness of the proliferative layer and total cartilage thickness were significantly reduced in the soft-diet group.

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Computational Modeling and Analysis of Ablative Composites Using Micro-tomographic Images (미세 단층 영상을 이용한 삭마 복합재료의 전산 모델링 및 해석)

  • Cheon, Jae Hee;Roh, Kyung Uk;Shin, Eui Sup
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.47 no.9
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    • pp.642-648
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    • 2019
  • In this study, Image-based computational analysis using the developed models was performed to predict the degradation of effective properties by ablation. The ablation tests of carbon/phenolic composites were performed using a 0.4 MW arc-heated wind tunnel. The carbon/phenolic composite samples were scanned using the micro-computed tomography (Micro-CT) to analyze the ablation characteristics according to a duration time of the ablation test. By calibrating the scanned images, computational models were developed that reflect the actual microstructure of the ablation composites. Also, nine computational models that reflect the actual pore shape were developed using the created cross-sectional images. Image-based computational analysis using the developed models was performed to predict the degradation of effective properties by ablation and the decrease of effective properties was confirmed with increase of porosity.

Internal Void Structure of Strandboard using X-ray Computed Tomography (X-ray 단층촬영기법을 이용한 스트랜드보드의 내부공극구조에 관한 연구)

  • Oh, Sei Chang
    • Journal of the Korean Wood Science and Technology
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    • v.36 no.6
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    • pp.13-22
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    • 2008
  • Internal voids affecting the mechanical properties of wood composite were classified into two catagories and characteristics of voids were examined according to density variation of strandboard. The void distribution and content of strandboard according to board density were measured by X-ray computed tomography system and analized using image processing software. Prior to investigation, the densities of strandboard were measured by densitometer and the results were showed high correlation with conventional oven drying method. Based on the image analysis conducted on captured images by X-ray tomography, low resolution can be used to capture the macro-voids (between strand) but not the micro-voids (within strands). Intermediate resolution can be used to capture both the macro and the micro-voids and high resolution can be successfully used to capture the majority of the micro-voids. The content of macro-void was measured and content of micro-void was computed by corresponding related equation. The macro-void distribution can be successfully understood and void content can be correctly estimated through the results.

REMINERALIZATION EFFECTS OF GLASS IONOMER RESTORATIONS ON ADJACENT INTERPOXIMAL-A MICROTOMOGRAPHIC STUDY (미세전산화 단층 촬영을 이용한 글라스 아이오노머 수복의 인접면 재광화 효과에 대한 연구)

  • Lee, Hyeok-Sang;Lee, Sang-Dae;Kim, Jung-Wook;Kim, Chong-Chul;Hahn, Se-Hyun;Jang, Ki-Taeg
    • Journal of the korean academy of Pediatric Dentistry
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    • v.31 no.3
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    • pp.474-480
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    • 2004
  • The purpose of this in vitro study was to compare the remineralizing effects of three glass ionomer cements (high filled glass ionomer cement, compomer, resin modified glass ionomer cement) with resin composite (control group) on incipient interproximal caries, and to assess long-term change of remineralization effect, in each material, evaluated by microtomography. Proximal restoration was simulated with tooth specimen and Glass Ionomer Cements. And each of these groups was placed into a closed container with artificial saliva at $37^{\circ}C$ and pH 7.0 for a time period of thirty days with constant circulation. At the end of thirty and sixty days, tomographic images were taken from these specimens with micro CT scanner. Materials used in this study were as follows. Group 1: Fuji IX GP (GC Corp., Tokyo, Japan) Group 2: Vitremer (3M ESPE, St. Paul, Minn., USA) Group 3: F2000 (3M ESPE, St. Paul, Minn., USA) Group 4: Z250 (3M ESPE, St. Paul, Minn., USA) Using density-measuring program, the micro-density of carious lesions on the specimens were measured. The mean density changes of each group were compared to the other groups to evaluate the effect of remineralization. The results were as follows: 1. The lesion density of all groups increased. 2. The mean density increase of Group 1, 2, 3 were higher than that of Group 4 every month(p<0.05). 3. There were significant differences of density increase among glass ionomer group(Group 1, 2, 3).

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LONG-TERM EVALUATING OF THE REMINERALIZATION OF INTERPROXIMAL CARIES ADJACENT TO GLASS IONOMER RESTORATIONS: A MICRO-CT STUDY (미세 전산화 단층 촬영을 이용한 글라스 아이오노머 수복물의 인접면우식 재광화 효과에 관한 장기간 연구)

  • Lee, Hyeok-Sang;Kim, Young-Jae;Kim, Jung-Wook;Jang, Ki-Taeg
    • Journal of the korean academy of Pediatric Dentistry
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    • v.33 no.3
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    • pp.498-503
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    • 2006
  • This in vitro study compared the remineralization of incipient interproximal caries in the presence of three glass ionomer cements (highly-filled glass ionomer cement, compomer, resin-modified glass ionomer cement) and a resin composite(control). The long-term changes in remineralization caused by each material were evaluated by microtomography. Proximal restoration was simulated by placing tooth specimens and the various glass ionomer cements in closed containers with artificial saliva at $37^{\circ}C$ and pH 7.0 for 30 days with constant circulation Tomographic images were obtained with a micro CT scanner at 90, 180, and 270 days, and density-measuring software was used to calculate the micro-density of artificial caries lesions in the specimens. The mean density changes were compared between groups in order to evaluate the effects of remineralization. All data were analyzed using one-way ANOVA and the post-HOC Tukey multiple comparison test at p<0.05. While the density of artificial caries lesions increased for all treatments, the increases for the three glass ionomer groups were significantly higher than that for the resin group in each three month period. As time went on, the amount of density increase of the glass ionomer groups decreased, and significant differences were found between the remineralization effects of the glass ionomer groups.

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ASSESSMENT OF THE CHEMOMECHANICAL CARIES REMOVING EFFICACY - MICROTOMOGRAPHIC STUDY - (화학.기계적 우식제거 효능의 평가에 대한 미세전산화 단층 촬영을 이용한 연구)

  • Hahn, Soo-Kyoung;Kim, Jung-Wook;Lee, Sang-Hoon;Kim, Chong-Chul;Hahn, Se-Hyun;Jang, Ki-Taeg
    • Journal of the korean academy of Pediatric Dentistry
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    • v.30 no.3
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    • pp.406-414
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    • 2003
  • Chemomechanical approach to caries removal was introduced in order to preserve the maximum amount of sound tooth structure. The efficacy of chemomechanical caries removal was assessed using microcomputed tomography which offers 3 dimensional data without destroying the tooth, and the V works program. In group 1, the density values of the sound dentin, carious dentin, and remaining dentin after chemomechanical treatment were analyzed. In group 2, the density values of the sound dentin, cavity wall prepared using high speed bur, and the remaining dentin after additional $Carisolv^{TM}$ gel application on the same cavity were analyzed. The results were as follows; 1. The density value of the remaining dentin after the $Carisolv^{TM}$ treatment was 81.8% of the sound dentin(p < 0.001). 2. The density value of the remaining dentin after the conventional rotary instrument showed no statistically significant difference from that of the sound dentin(p = 0.234).

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