• Title/Summary/Keyword: 물질검출

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글로우방전을 이용한 생체시료 중 극미량성분분석에 관한 연구

  • 김효진
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 1994.04a
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    • pp.275-275
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    • 1994
  • 생체시료 중 극미량성분분석에 관한 필요성이 높아지고 있으며 기존의 분석기기를 사용하여 분석방법을 개발하는 연구나 새로운 분석기기를 개발하는 연구들을 통하여 이들 물질들을 분석하고자 하고있다. 특히 극미량성분인 경우 생체내에 수십 Pg이 존재하면서 이들의 농도변화가 생리활성에 변화를 주기 때문에 검출한계가 낮은 검출기가 필요하게되며 또한 생체시료중의 여러물질들로 인하여 이들을 분리하는 크로마토그라피기술과 이들이 분리된 후 실제로 어떠한 물질인지를 확인할 수 있는 즉 정성까지 가능한 검출기의 개발이 요구되고 있다.

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Detection of Ultrasonics by Optical Fiber Fabry-Perot Interferometer (광섬유 Fabry-Perot 간섭계를 이용한 초음파의 검출)

  • 지성훈;박동빈;김달우
    • Proceedings of the Optical Society of Korea Conference
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    • 2003.07a
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    • pp.298-299
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    • 2003
  • 초음파는 일반적으로 물질의 내부결함을 측정하거나 결정입경과 같은 물질의 특성을 측정하는데 사용된다. 현재 초음파를 검지하는 방법으로는 탐촉자를 물질에 접촉시켜서 초음파를 측정하는 접촉식 방법이 널리 사용되고 있다. 따라서, 이러한 접촉식 초음파 검출방법은 원격탐사를 하는데에 어려움이 있다. 이런 문제점을 보완하기 위하여 본 연구에서는 패브리-페로 간섭계(Fabry-Perot interferometer)를 이용하여 비접촉식으로 초음파를 검출하는 방법에 대하여 실험하였다. (중략)

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Screening and Possibility of Semi-quantitative Analysis of Explosive Compounds in Soil Using EXPRAY$^{(R)}$ Explosives Field Detection Kit (화약물질 현장검출시약 EXPRAY$^{(R)}$를 이용한 토양내 화약물질 스크리닝 및 준정량화 가능성)

  • Bae, Bum-Han;Cho, Jung-Hyun
    • Journal of Soil and Groundwater Environment
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    • v.14 no.2
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    • pp.45-53
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    • 2009
  • A quick and simple detection method of explosive compounds in environmental matrix (soil and water) can provide a screening step which reduces the number of unnecessary samples and the cost of expensive laboratory analysis at a site investigation. A commercially available EXPRAY$^{(R)}$Explosives Field Detection Kit (EXPRAY) was used to determine the minimum detection concentration and to test the possibility of semi-quantitative analysis of 14 explosive compounds using standard solutions. The results showed that EXPRAY could detect 5 explosive compounds, TNT, RDX, HMX, Tetryl, and TNB, out of 14 US EPA designated explosives. The minimum detection limit of the nitramine explosives was 14 ng/$^2$ for HMX and RDX. EXPRAY was more sensitive to nitroaromatics than the nitramines and the minimum detection limits per unit area (mm$^2$) for Tetryl, TNB, and TNT, were 3 ng, 3 ng, and 0.3 ng, respectively. The semi-quantification of 5 explosive compounds in an order ofmagnitude could be achieved by the intensity of developed color only when EXPRAY was applied on the standard solutions under controlled laboratory conditions. With contaminated soil samples, however, only the presence and type of explosive compounds was identified. Therefore, EXPRAY is an economic and sensitive method that can be used in a screening step for the identification of explosives in the field samples.

Recent Progress in Membrane based Colorimetric Sensor for Metal Ion Detection (색 변화를 활용한 중금속 이온 검출에 특화된 멤브레인 기반 센서의 최근 연구 개발 동향)

  • Bhang, Saeyun;Patel, Rajkumar
    • Membrane Journal
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    • v.31 no.2
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    • pp.87-100
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    • 2021
  • With a striking increase in the level of contamination and subsequent degradations in the environment, detection and monitoring of contaminants in various sites has become a crucial mission in current society. In this review, we have summarized the current research areas in membrane-based colorimetric sensors for trace detection of various molecules. The researches covered in this summary utilize membranes composed of cellulose fibers as sensing platforms and metal nanoparticles or fluorophores as optical reagents. Displaying decent or excellent sensitivity, most of the developed sensors achieve a significant selectivity in the presence of interfering ions. The physical and chemical properties of cellulose membrane platforms can be customized by changing the synthesis method or type of optical reagent used, allowing a wide range of applications possible. Membrane-based sensors are also portable and have great mechanical properties, which enable on-site detection of contaminants. With such superior qualities, membrane-based sensors examined in the researches were used for versatile purposes including quantification of heavy metals in drinking water, trace detection of toxic antibiotics and heavy metals in environmental water samples. Some of the sensors exhibited additional features like antimicrobial ability and recyclability. Lastly, while most of the sensors aimed for a detection enabled by naked eyes through rapid colour change, many of them investigated further detection methods like fluorescence, UV-vis spectroscopy, and RGB colour intensity.

Development of an electrochemical detector using Prussian blue modified indium tin oxide electrode (Prussian blue가 전착된 indium tin oxide전극을 이용한 전기화학적 검출기의 개발)

  • Yi, In-Je;Kim, Ju-Ho;Kang, C.J.;Kim, Yong-Sang
    • Proceedings of the KIEE Conference
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    • 2005.07c
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    • pp.2404-2406
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    • 2005
  • 본 연구에서는 전기촉매제를 사용하여 증가된 감도를 가지는 검출 시스템을 제작하였다. 전극과 검출물질 사이의 산화환원반응을 촉진시키기 위한 물질로 Prussian blue (PB)를 indium tin oxide (ITO) 전극에 전착하였다. 본 실험에서는 분석물질의 이동 및 분리를 위하여 모세관 전기영동방법을 사용하였으며 측정방법은 전류량법을 사용하였다. 전착된 PB 박막의 특성은 원자 현미경으로 분석하여 0.1V, 3min의 전착조건으로 최적화하였다. 전기 촉매제로써의 PB의 특성을 확인하기 위하여 ITO 전극만을 사용한 전기화학적 검출기와 비교하였으며 본 연구에서 제안된 검출기의 감도가 20배정도 더 좋다는 것을 확인하였다.

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생물 공학 의약품의 품질관리에 관한 연구(비방사능 물질 표지법을 이용한 숙주유래 DNA의 검출법 개발)

  • 용군호;민홍기;김창민;오호정;한강현;최규실
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 1993.04a
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    • pp.59-59
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    • 1993
  • 비방사능물질인 Biotin을 DNA probe에 표지하여 nonisotopic hybridization 방법을 사용하여 감도를 높임으로써, 손쉽게 생물공학 의약품의 품질관리에 사용되도록 하였다. Bethesda Research Laboratories(BRL) 회사 제품인 biotinylated probes-avidin alkaline phosphatase를 이용한 chemiluminescene detection방법으로 행하여 λ phage DNA, yeast DNA, E.coil DNA의 한계 검출 농도를 알아내고, 생물 공학 제품에 적용하였다. Dot blot hybridization 방법으로 행하여 λ phage DNA는 0.1pg, Yeast DHA는 4.5pg, E. coli DNA는 8.9pg까지 검출되었고, 기존 생물공학 제품에서는 숙주 유래 DNA가 전혀 검출되지 않았다.

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A study on the emission of fluorine-based chemicals and the detection of perfluorooctane sulfonic acids(PFOS) and perfluorooctanoic acids(PFOA) in domestic main rivers (국내 불소계 화학물질 배출 현황 및 주요 수계의 과불화화합물(PFOS, PFOA) 검출 특성에 관한 연구)

  • Sam-Bae Park;Yoon-Young Chang
    • Journal of the Korea Organic Resources Recycling Association
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    • v.31 no.2
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    • pp.5-18
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    • 2023
  • As a result of the survey on the emission status of fluorine-based chemicals in Korea, 13 kinds of substances, including hydrogen fluoride (91%) and perfluorocarbons (5%), were emitted in workplaces. By regional groups, about 98% was emitted in the Gyeongbuk, Gyeonggi and Chungcheong regions, and about 98% in three sectors of industry related to manufacture of electronic parts, chemicals and non-metallic mineral products. The detection status of PFOS and PFOA in domestic main rivers was continuously detected in the Nakdong River, the Geum River and the Anseong Stream estuary with high fluorine-related chemical emissions, and four sites of PFOS and two sites of PFOA were detected for the first time in 2021. PFOS and PFOA were continuously detected in relatively high concentrations in the rivers where there were many semiconductor and display related sectors of industry.

Changes of Fluorescent Substances and Free Amino Acids in Formed Eggs of the Silkworm(Bombyx mori) (가잠조성난의 형광물질과 유리아미노산의 변화)

  • 성수일;박광의;김주읍
    • Journal of Sericultural and Entomological Science
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    • v.20 no.1
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    • pp.11-14
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    • 1978
  • This experiment was attempted to investigate the effect of removal of suboesophageal ganglion of Bombyx mori on the changes of free amino acids and fluorescent substances by means of paper chromatography. 1. There are no differences of quantity and component of free amino acids of formed eggs in moths between treatment and control. 2. Riboflavine content of formed eggs in treated moths is less than that of formed eggs in untreated moths. 3. Fluorescent substance which appeared on Rf value 0.06 was not detected in formed eggs of treated moths but found in those of control. 4. Fluorescent substance which appeared on Rf value 0 was noted in formed eggs of treated moths but not in those of control.

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염소계유기용제 및 유류물질에 의한 산업단지 지하수 오염특성

  • Kim Jong-Ho;Kim Rak-Hyeon;Ryu Gwan-Hui;Park Jeong-Gu;Seo Chang-Il;Jeon Gwon-Ho;Jeong Jang-Sik
    • Proceedings of the Korean Society of Soil and Groundwater Environment Conference
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    • 2006.04a
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    • pp.355-359
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    • 2006
  • 토양에 누적된 오염물질은 지하수 유동과 연계하여 점차 주변지역으로 확산된다. 본 조사는 오염의 개연성이 높은 산업단지를 선정하고 그 중에서도 유해화학물질의 사용이 많은 지역을 대상으로 토양과 지하수의 오염도조사를 수행하였다. 토양오염도 조사는 160개 지점에서 토양시료를 채취하여 오염물질을 분석하였으며 분석결과 TPH물질은 최고 23,151mg/kg, BTEX는 최고 1,657mg/kg로 검출되었다. 오염특성은 유류(TPH, BTEX) 물질 이외에도 TCE, PCE◎물질과같은 염소계 유기용제에 의한 오염도 확인할 수 있었으나 중금속 물질에 의한 오염은 우수 방류구와 같은 일부 지역에서 검출되었다. 지하수 수질의 경우 페놀, 비소, 납, BTEX, TCE, PCE 물질들이 복합적으로 오염되어있는 것으로 나타났다.

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Adaptive Window-based Detection of Narcotics and Explosives using IMS Signals in Cargo Containers (화물 컨테이너 내 IMS 신호를 이용한 적응 윈도우 기반 마약 및 폭발물 검출)

  • Ju, Heesong;Kim, Donghyun;Cho, Sungyoon;Park, Kyungwon;Kim, Yangsub;Jeon, Wongi;Kwon, Kiwon
    • Journal of Internet Computing and Services
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    • v.23 no.3
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    • pp.57-65
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    • 2022
  • International attempts to smuggle narcotics and explosives using ship or aircraft cargoes are on the rise. With the recent increase in the number of detection cases of narcotics and explosives in Korea, it is important to detect dangerous material (narcotics and explosives) through container searches at ports and airports, which are the main routes. This paper proposes a technique to detect dangerous material in cargo containers using the sampled output signal of ion mobility spectroscopy (IMS). The proposed technique estimates parameters such as a threshold, a window length, and a noise level for ion detection of the target dangerous material by using known materials in the initialization stage. The estimated parameters are used to detect the ions of the dangerous target material inside the containers. The proposed technique can be applied when the peak value of the IMS signal and the ion mobility are varying due to container environments.