• Journal of Preventive Medicine and Public Health
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• v.22 no.3 s.27
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• pp.355-367
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• 1989

This study examined the physical and mental health factors affecting the industrial accidents of 142 injured and 1,212 uninjured workers in the shipbuilding industry from 1986 to 1988. The results acquired from the Todai Health Index (THI) and from analysis of the health examination were as follows: 1. Among the personal characteristics of the workers, the educational level of injured workers was significantly lower than that of the uninjured workers. 2. Among the physical characteristics, vision and $R\ddot{o}hrer$ Index of the injured workers were lower than those of the uninjured workers, and the difference was statistically significant. On the other hand, the differences in height, weight, hearing function, hematocrit, blood pressure, urine test, and X-ray findings were not statistically significant between the injured and uninjured workers. 3. The score of the THI questionnaire on the physical and mental health of the injured workers was higher than that of the uninjured workers, and the difference was statistically significant. 4. Form the THI score, the industrial workers had complained more about mental health than physical health and there was a statistically singinficant relation with the industrial accidents. 5. The relative risk expressed in terms of the odds ratio was 2.9 for poorer vision, 2.7 for a lower educational level, 2.2 for a higher THI score and 1.6 for overdrinking. 6 Educational level, vision, and the THI score were selected as significant factors influencing industrial accidents based on a log-linear model. According to the results of this model by logistic analysis, the odds ratio of industrial accidents was 1.8 for a lower educational level, 1.7 for poorer vision, and 1.6 for a higher THI score. 7 By event history analysis with the dependent variable as the duration of work at the time of the industrial accident, educational level, age, $R\ddot{o}hrer$ Index and THI score were the statistically significant variables selected, and the hazard rate of industrial accident occurrence was 0.24 for a lower educational level, 0.92 for age, 0.99 for a lower $R\ddot{o}hrer$ Index and 2.72 for a higher THI score. As we have seen, educational level and THI score were the most significant factors affecting the hazard rate of industrial accidents. Vision, $R\ddot{o}hrer$ Index, age, and drinking behavior were also statistically significant variables influencing industrial accidents. Therefore, in order to prevent industrial accidents, it is necessary to establish a health management plan for industry which can objectively evaluate not only the physical but also the mental health of the workers. If we use this type of study as a prospective study design, we can determine the relative risk of physical and mental health factors on industrial accidents. Furthermore, it is expected that this type of study will provide workers at high risk with more precise basic data for a health managment plan for industrial accident prevention.

• Journal of Preventive Medicine and Public Health
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• v.30 no.3 s.58
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• pp.599-608
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• 1997

We studied on change of lens accommodation and pupil light reflex caused by VDT work in six women and compared them with those of other office works. The results were as follows. 1. In VDT work the accommodation contraction velocity decreased during the first 2-hr VDT task, then recovered markedly by the end of the one-hour lunch break, and decreased again by the end of the 2nd 2-hr VDT task. Changes of relaxation velocity showed similar pattern although it was less typical than that of contraction velocity 2. There was no marked change in accommodation contraction velocity and amplitude of accommodation in general office work and near-distance office work, and in the near-distance office work accommodation relaxation velocity decreased according to work load without recovery after lunch break. 3. Initial pupil diameter, initial pupil area of light reflex decreased significantly during VDT task only in VDT work and didn't recover after lunch break. These results suggest possibility that changes of accommodation contraction velocity, accommodation relaxation velocity, near point distance, and pupil diameter and area are useful in evaluating characteristics of VDT work. For this, more research adjusted individual differences, circadian rhythm, emotional stress needs.

• Journal of Life Science
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• v.26 no.7
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• pp.819-825
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• 2016

The present study was done to assess the diversity of the bacterial community associated with Ulva pertusa collected from Jeju Island using Restriction Fragment Length Polymorphism (RFLP) marker analysis. For RFLP analysis, a total of 145 bacterial strains associated with Ulva pertusa were screened and cultivated using Marine agar and R2A agar. The PCR amplicons of the 16S rRNA gene from all the isolated strains were digested with HaeIII and RsaI restriction enzymes and then classified into different groups according to their restriction patterns. Strains selected based on the RFLP patterns showed more than 91% 16S rRNA gene sequence similarity when compared with known bacterial species, which include 4 phyla - proteobacteria (alpha-proteobacteria, beta-proteobacteria, gamma-proteobacteria - 63%), firmicutes (11%), actinobacteria (4%), bacteroidetes (22%)–as well as 7 classes (actinobacteria, flavobacteriia, cytophagia, bacilli, α-proteobacteria, γ-proteobacteria, β-proteobacteria), 13 orders, 18 families, and 27 genera. These results confirmed a wide diversity of bacterial communities as contrasted with other regions. The newly isolated 10 strains, which show 16S rRNA sequence similarity of <97% compared to previously identified bacteria, could be noble species. Further experiments, such as morphological, physiological, and biochemical classification, are necessary to confirm the novelty of the newly isolated 10 strains.

• Journal of Life Science
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• v.17 no.12
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• pp.1627-1633
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• 2007

c-Jun N-terminal kinase (JNK)-interacting protein 1 (JIP1), also known as Islet-brain 1 (IB1), is a scaffold protein that is highly expressed in neurons and pancreatic ${\beta}-cells$. In this study subcellular localization of JIP was investigated in cultured rat hippocampal neurons using an antibody that recognize all variants of JIP1, JIP-2 and JIP-3. The overall expression profile of JIP is punctate throughout soma and dendrites. Statistic analysis showed that $54.8{\pm}4.0%\;and\;94.1{\pm}4.5%$ of total JIP immunopuncta overlapped with those of excitatory postsynaptic markers SD-95 and ${\alpha}Camik$, respectively. In contrast, only $8.6{\pm}0.5%\;and\;7.3{\pm}0.5%$ of JIP clusters overlapped with those of inhibitory postsynaptic markers glycine receptor (GlyR) and gephyrin, respectively. JIP clusters overlapped or juxtaposed with SV2 but not GAD, markers for general and inhibitory nerve terminals, respectively. A substantial fraction $(29.3{\pm}1.0%)$ of flotillin immunopuncta, a marker for lipid rafts, clusters overlapped with those of JIP. In addition, JIP was highly expressed in some select ends of dendrites but minimal in axons. These data suggest important roles of JIP in excitatory postsynaptic sites, lipid rafts and dendritic ends.

• Journal of Life Science
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• v.21 no.2
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• pp.176-182
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• 2011

Deep seawater (DSW) generally refers to seawater at depths equal to or greater than 200 meters. DSW is rich in inorganic materials which have attracted attention for its various applications. In this study we investigated the effects of the DSW upwelled from the East Sea, offshore Yang Yang (KangWon-do, Korea), on the expression of ${\mu}$-opioid receptor (MOR) of cultured rat hippocampal neurons. Neurons were grown in a minimal essential medium containing 10% (v/v) fetal bovine serum and either 25% (v/v) distilled water, or hardness (H) 800, or H 1000 DSW. Cultures grown in the presence of DSW with H 800 and H 1000 exhibited robust MOR immunoreactive signals in both neurons and astrocytes. Interestingly, the increase in MOR immunoreactive signals was more dramatic in astrocytes than in neurons. Statistical analysis revealed that the relative intensities for MOR clusters increased approximately 4-fold in astrocytes cultured in H 800 and H 1000 media. These increases were statistically very significant (p<0.001). In contrast, the increase in intensities for MOR immunoreactive signals was relatively less dramatic in neurons, where only the increase in the H 1000 culture was statistically very significant (p<0.001). These results indicated that DSW promotes expression of MOR in both neurons and astrocytes, and more significantly in the latter.

• Journal of Life Science
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• v.23 no.2
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• pp.324-331
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• 2013

The addition and removal of N-acetylglucosamine (GlcNAc) molecules on serine or threonine residues of a protein is called O-GlcNAcylation. This post-translational modification occurs on both cytoplasmic and nuclear protein, and is fast and reversible as comparable to phosphorylation. In contrast to the phospho-signaling cycles, this emerging moon-lightening signaling is cycled by only two enzymes, O-GlcNAc transferase (OGT) and O-GlcNAcase (OGA). The simple machinery is a good evolutionary adaptation of a cell for quick accommodation to continuously fluctuating intra- and extracellular microenvironments. Rather than "switching" on or off a specific proteins - this would be done by phosphorylation where numerous specific kinases and phosphatases are involved - O-GlcNAcylation would play a "rheostat" which would be much more delicately increase or decrease the efficacy of signal transductions in response to cellular nutrient and stress conditions. Interestingly, recent evidence indicates that O-GlcNAc is further modified by phosphorylation. The O-GlcNAc-P will upgrade the modulation efficiency of cellular processes to continuous 'analogue' level. So far, only one protein AP180 was reported to have O-GlcNAc-P on Thr310. But, proteomic data from our laboratory indicate that there are multiple O-GlcNAc-P proteins, constituting "O-GlcNAc-P'om". This will focus on the possibility of existence of "O-GlcNAc-P'om".

• Transactions of the Korean Society of Mechanical Engineers B
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• v.38 no.11
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• pp.935-942
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• 2014

A numerical analysis of the effect of the Prandtl number on the natural convection in a cold outer tilted square enclosure with an inner hot circular cylinder is presented. Several Prandtl numbers (Pr=0.1, 0.7, 7) are considered, with different angles($0^{\circ}$, $15^{\circ}$, $30^{\circ}$, $45^{\circ}$) for the enclosure and Rayleigh numbers ($Ra=10^3$, $10^4$, $10^5$). The effect of the Prandtl number on the natural convection is analyzed using isotherms and streamline and surface-averaged Nusselt numbers. The flow and heat transfer characteristics are found to be dependent on the time for $Ra=10^5$ and Pr=0.1 at angles of $0^{\circ}$ and $45^{\circ}$. However, in the other cases, the flow and heat transfer characteristics are independent of the time.The surfaceaveraged Nusselt number increases with an increase in the Prandtl number. As the Prandtl number increases, the Nusselt number becomes larger regardless of the angle for $Ra=10^5$. In particular, the Nusselt number steeply increases when the angle is $45^{\circ}$ for $Ra=10^5$ and Pr=0.1.

• The Korean Journal of Nuclear Medicine
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• v.5 no.2
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• pp.57-64
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• 1971

The organ distribution study and the whole body scan were done in the albino rats at intervals of 5, 30, 60, 90 and 120 minutes after the intravenous injection of $^{99m}TC$-pertechnetate absorbed in Sephadex beads of $20{\sim}80$ micra in diameter. Effect of additional injection of physiological saline and saline absorbed in Sephadex beads of $20{\sim}80$ micra in diameter on the scan and organ distribution were also studied. The results were as follows. 1. Five minutes after the injection of $^{99m}TC$-pertechnetate absorbed in Sephadex beads of $20{\sim}80$ micra in diameter, Sephadex was well trapped in the lungs, with which the excellent lung scan was obtained. Two hours after the injection, kidneys were well visualized instead of lungs, which suggested that kidney acts as the excretory organ. Five minutes prior to scan, additional injection of physiological saline absorbed in Sephadex above mentioned was done. The bladder was also well visualized together with the kidneys. 2. In the distribution studies, most of radioactivity was detected in the lungs at 5 minutes and was gradually transferred chiefly to the kidneys and bladder and partly to the liver. 3. Additional injection of physiological saline resulted in a rapid transfer of $^{99m}TC$ trapped in the lung to both the kidneys and liver. 4. Additional injection of physiological saline absorbed in Sephadex beads of $20{\sim}80$ micra in diameter resulted in a rapid transfer of $^{99m}TC$ trapped in the lung to only the urinary system. 5. Results of these studies suggested that; a) Other nutrients and therapeutic compounds may be carried into the lungs along with Sephadex beads and then released in high concentration, which would exert greater therapeutic effect locally than that of the usual administration. b) Some radionuclides absorbed in Sephadex could be used as the lung scan agents, the flushing out of which by Sephadex-saline also give satisfactory renal and bladder scans. c) Other potent therapeutic radionuclides could be retained for some time by this method, which can be in the lungs easily flushed out within 2 hours.

• Korean Journal of Organic Agriculture
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• v.25 no.1
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• pp.219-231
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• 2017

The aim of this study was to determine the effects of feeding of different organic diets (based on fatty acid contents) on CLA and fatty acid concentration of raw milk. Total two hundred and ninety Holstein cows were divided into control, treatment 1 and treatment 2 groups according to the parity and milk yield. Control diet was contained higher C16:00, C18:2 and SFA. Treatment 1 diet was higher in C18:1, C18:2, UFA and treatment 2 diet was higher in MUFA and C18:3 and PUFA. The results indicated that the C16:0 concentration in raw milk was greater in the group of treatment 2 than in control and treatment 1 (p<0.05). The concentration of CLA in treatment 2 was higher compared to treatment 1 and control groups (p<0.05). The ration of n-3/n-6 was higher in treatment 2 group compared with control and treatment 1 (p<0.05). In conclusion, feeding 100% of grass feed for dairy cows increases CLA and n-3 content in milk. From now on, basis on our study, development of functional milk will increase a health of children and old people.

• The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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• v.10 no.3
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• pp.164-170
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• 2005

To investigate the aquatic environmental factors and processes controlling primary production in the Seomjin River estuary, chlorophyll a, nutrients, pH, SS, DO, temperature, salinity and primary productivity were measured in February, April, August and October, 2001. Primary productivity values ranged between 50.7 and 14,120.3 mg C $m^{-3} day^{-1}$ during the sampling period. In contrast to other estuaries, light condition did not seem to be the important limiting factor far primary production due to high water-column transparency during most of the time. The autumn bloom occurred in regions where salinity values ranged between 10 and 20 psu. This phenomenon appeared to develop every year and deserves further investigation. The behavior of nutrients, which is one of the major factors controlling the primary productivity, appeared to be governed by salinity regimes. The main source of nitrogenous nutrients seemed to be the freshwater runoff from the Seomjin River. However, that of phosphorus seemed to be from the industrial wastewater in Gwangyang area. The primary pro-duction of phytoplankton in the study area varied with space and time, showing a close correlation with water column transparency, and exhibited higher values compared to those of adjacent coastal regions in Gwangyang Bay.