• Korean Journal of Psychosomatic Medicine
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• v.29 no.2
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• pp.121-127
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• 2021

Objectives : The characteristics of depressive symptoms in patients with cancer is different from those in control group. However, few research has focused on the association between depressive symptoms in cancer patients. The aim of this study was to compare the network structure of depressive symptoms between patients with cancer and normal control. Methods : This study was based on cohort data from Korea National Health and Nutrition Examination Survey in 2016-2018. The Patient health Quetionnaire-9 (PHQ-9) was used to assess depressive symptoms in 599 patients with cancer and 599 age-sex matched controls. We estimated network structure of depressive symptom using Isingfit model. Results : There was no significant difference of each PHQ-9 item score. There were strong associations between symptoms were concentration problem-psychomotor activity, anhedonia-depressed mood, and depressed mood-suicidal ideation in both groups. Strength centrality of worthlessness was significantly higher in patients with cancer. Conclusions : These results suggest that worthless is associated with other depressive symptoms more tightly in patients with cancer. Worthless can serve as important treatment targets for intervention of depression in patients with cancer.

• Proceedings of the Korean Society of Computer Information Conference
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• 2014.07a
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• pp.15-16
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• 2014

본 논문은 음악 치료 전문가들로부터 수집한 음악 치료 프로그램에 관한 지식과 규칙을 수집하여 구성된 전문가 시스템을 도입하여 자동으로 우울증 환자를 위한 추천 음악 치료 시스템을 설계하는 것을 목표로 한다. 제안한 시스템은 음악 치료 전문가들로부터 수집한 수많은 음악 치료 프로그램 중 뇌파 측정을 통해 환자에게 가장 효과적인 치료 프로그램을 선별하고 환자에게 제공하여 치료 효과를 극대화하는 것을 목표로 한다. 제안 시스템은 우울증 환자들의 치료를 위해 뇌파 측정을 입력 받아 분석하여 환자의 증상을 완화하고 치료 효과가 가장 좋은 음악 치료 프로그램을 선별하기 위해 인공 지능 기술들인 전문가 시스템(Expert System) 기법에 기반 한 음악 치료 시스템을 설계하고 제안한다.

• Proceedings of the Korea Institutes of Information Security and Cryptology Conference
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• 2002.11a
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• pp.629-632
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• 2002

공공기관은 자신의 정보시스템에 대한 보안 대책을 수립하기 위하여 자체 보안·분석평가를 수행함으로써 적절한 보안 목표와 방향을 설정해야 한다. 하지만, 현재 연구되어 있는 위험분석 및 보안평가방법론등은 복잡하고 전문적인 사항이 많으므로 자체 보안분석을 수행하기에는 인력 및 비용이 많이 소요된다. 이를 위하여 본 논문에서는 정보시스템의 위험분석방법론에서 제시하는 자산, 취약점, 위협, 대응책에 보안평가방법론을 포함하여 정보시스템에 대한 모델링, 가정, 증상, 원인, 해결책등을 통한 자가진단 보안 분석·평가 방법을 제시한다.

• Korean Journal of Psychosomatic Medicine
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• v.30 no.1
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• pp.30-37
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• 2022

Objectives : The purpose of this study was to develop a cognitive-behavioral intervention for college students at high risk for mental health and to investigate its effect on mental health outcomes. Methods : The program was developed to reduce depressive symptoms and adverse outcomes while promoting resilience and positive effects. It consisted of eight sessions in a small group format for eight weeks. Thirty subjects at high risk for mental health participated in the program. Outcomes on the depressive symptoms, resilience, satisfaction with life, negative affect, and positive affect were evaluated at pre-and post-intervention. Results : Depressive symptom scores reduced significantly post-intervention compared to pre-intervention (t=3.51, p=0.002). Resilience scores (t=-3.65, p=0.001) and satisfaction with life scores (t=-3.00, p=0.006) increased after intervention than pre-intervention. Positive affect scores decreased post-intervention (t=2.28, p=0.031). There was no significant difference between pre-and post-intervention negative affect scores (t=-0.94, p=0.356). Conclusions : Present study demonstrated that group-based cognitive-behavioral intervention could be helpful for college students at high risk for mental health to reduce mental health symptoms and improve healthy protective factors.

• Journal of Yeungnam Medical Science
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• v.24 no.1
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• pp.1-10
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• 2007

The chronic fatigue immune dysfunction syndrome (abbreviated CFIDS or CFS) is a disorder characterized by debilitating fatigue(over 6 months.), along with cognitive, musculoskeletal, and sleep abnormalities. The etiology of this illness is unlikely to be a single agent. Findings to date suggest that physiological and psychological factors work together to predispose and perpetuate the illness. Diagnosis is made difficult by the nonspecific clinical findings and no available diagnostic testing. With no known cause or cure for the chronic fatigue and immune dysfunction syndrome, treatment is based on relieving symptoms and improving the quality of life of affected patients. There is emerging evidence that chronic fatigue syndrome may be familial. In the future, studies will examine the extent to which genetic and environmental factors play a role in the development of chronic fatigue syndrome. Most patients with CFS have psychiatric problems such as a generalized anxiety disorder, or major or minor depression, therefore, these mental health disorders may be correlated with the pathophysiology of the CFS. The treatment for CFS must be individualized, due to the heterogeneity of the CFS population. Also the treatment of CFS is built on a foundation of patient-physician relationship, respect and advocacy.

• Journal of Korean Academy of Nursing
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• v.5 no.2
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• pp.51-73
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• 1975

인간은 누구나 자기 인생과정 중 우울한 때를 만날 수 있다. 실로 인생 그 자체가 참을 수 없는 우울의 연속인지도 모른다고 느끼는 사람도 있을 수 있다. 특히 대인관계의 실패나 인생목표의 좌절, 심지어 사소한 사건에서의 실망은 곧 잘 인간에게 여러 가지 감정반응을 일으킨다. 이는 정신건강이 건전한 사람에게는 문제가 될 수 없지만 신경증인 사람에게는 자신의 안정감을 보호하기 위해 현실과 환상의 세계에서 심각한 투쟁을 하고 있다. 그러므로 신경증적인 사람이 자신의 보호에 실패하였을때 불안이나 우울의 정도가 건강한 사람보다 그 농도가 짙게 되어진다고 말할 수 있다. 특히 신경증적 우울은 저하된 자기존중이나 자기의 무가치로 특징지어지며 여러 가지 신체증상도 있고 이러한 증상들은 독립성 강퇴나 죄의식 또는 흥미저하로 이끌어 종극에는 자살을 시도하려는 경향도 나타낸다. 바로 이리한 자살로까지 이끄는 우울의 현상이 저자로 하여금 증례를 찾아 연구해 보겠다는 의욕을 만들게 한 것이다. 이 증례에서 나타난 가정과 결론은 다음과 같다. \circled1 우울반응은 Separation파 loss의 한 반응이다. \circled2 연속된 긴장, 새로운 직장 또는 반복된 실직, 부모의 어린시절의 사별. 창녀생활. 새로운 문화의 적응모국어의 기억상실. 환자의 성격 그리고 환경 등이 우울로 이끌게 한 요인들이다. \circled3 자살은 개인의 양가감정을 나타내는 매우 복잡한 심리학적 반응이다. 즉 그것은 죽고싶은 비관적인 표현일수도 있고 동시에 살고싶은 욕망의 표현일수도 있다.

• Journal of Dental Rehabilitation and Applied Science
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• v.35 no.3
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• pp.123-131
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• 2019

Burning mouth syndrome (BMS) is defined as the xerostomia, burning sensation and various discomfort of tongue and oral mucosa. BMS can occur in both men and women, but is more frequent in middle-aged menopausal women. Because exact cause can't be identified clearly and it is hard to make diagnosis in clinic, the purpose of the treatment have been to relieve symptoms. Etiology of BMS is divided into local, systemic, and psychological factors. ${\alpha}$-lipoic acid, clonazepam, supplemental therapy and cognitive behavior therapy can be prescribed for BMS. Nowdays, many experts focus attention on effect of combination therapy. It is necessary to solve the symptoms of the patients by combination of pharmacological approach and psychotherapy with cognitive behavior therapy considering the factors in various aspects.

• Journal of the Korean Society of Radiology
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• v.84 no.5
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• pp.1017-1030
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• 2023

Radiofrequency ablation (RFA) is a non-surgical treatment for symptomatic, benign thyroid nodules. This treatment works by heating and destroying the nodule tissue, which results in reduction of its size and alleviation of the symptoms involved. RFA is indicated for nodules which are confirmed to be benign on two or more cytological or histological examinations, and which result in clinical symptoms requiring medical treatment. It is associated with good short-term outcomes on one-year follow-up; however, 20%-30% of the nodules regrow after more than three years. Therefore, on the basis of long-term follow-up, management of regrowth is key to patient care following RFA. Regrowth is more likely to occur in nodules that are large in size prior to RFA, and in those with high or increased vascularity. Recently, new techniques such as hydrodissection, artery-first ablation, and venous ablation have been introduced to inhibit regrowth. In addition, appropriate criteria for additional RFA should be applied to manage regrowth and prolong its therapeutic effects. RFA is essentially an alternative to surgery; therefore, the ultimate goal of this procedure is to avoid surgery permanently, rather than to achieve temporary effects.

• Journal of Oral Medicine and Pain
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• v.37 no.1
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• pp.27-33
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• 2012

Oral lichen planus(OLP) is a chronic inflammatory disease with cell-mediated immune responses, but the exact cause is unknown. The treatment aim of OLP is not complete cure but to alleviate symptoms. In this study, two kinds of corticosteroid gargling solutions used for comparing the effects. From 2002 to 2010, 180 patients diagnosed with oral lichen planus and received topical steroid therapy in the Pusan National University Dental Hospital. Each of two types of solution contained dexamethasone (dexamethasone disodium phosphate) and prednisolone ($solondo^{(R)}$). A period of relief of symptoms and recurrence was recorded. The group using solution containing dexamethasone(dexa gargle) was prescribed to 33 patients(25 female, 8 male) and another group containing prednisolone (solon gargle) included 147 patients (114 female, 33 male). The effect of dexa gargle seemed faster than the solon gargle. There was no significant difference for recurrent rate between the groups using dexa and solon gargle.

• Clinical and Experimental Pediatrics
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• v.49 no.11
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• pp.1180-1185
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• 2006

Purpose : The aims of this study were to verify the incidence of hypohidrosis and to determine the predictive value of noninvasive indicator test ($Neurocheck^{TM}$) for sweating after administration of topiramate in newly diagnosed pediatric epileptic patients. Methods : A total of 46 epileptic patients (22 boys; 24 girls) on topiramate treatment were evaluated in this study at the Department of Pediatrics, Chonbuk National University Hospital, from October 2004 to July 2005. We measured sweating functions using a noninvasive sweating test ($Neurocheck^{TM}$) before topiramate medication, and after 3 months when topiramate reached its target dosage. We performed a direct questionnaire survey for the hypohidrosis related symptoms during topiramate treatment. Results : The mean age was $7.8{\pm}3.2year$. The mean dosage of topiramate was $4.5{\pm}0.8mg/kg/day$. Among the patients, there were 40 complex partial seizures, one simple partial seizure, two partial seizures with secondarily generalization, two generalized seizures, and one Lennox-Gastaut syndrome case. Of the 46 epileptic patients, 17 patients (37.0 percent) experienced hypohidrosis and hypohidrosis related symptoms, 12 (26.1 percent) had facial flushing, four (8.7 percent) had heat intolerance, one (2.2 percent) had lethargy, but no one had anhidrosis. Among the 17 patients, the mild group numbered 12 and the severe group totalled five. Hypohidrosis by $Neurocheck^{TM}$ was diagnosed in 16 patients. The overall measures of agreement between $Neurocheck^{TM}$ and the survey was 76.5 percent. The specificity of this test was 89.7 percent. Patients who showed a time delay after medication, especially over 3 minutes, were seen only in the severe group. Conclusion : $Neurocheck^{TM}$ could be clinically useful to detect and predict topiramate induced hypohidrosis in pediatric epileptic patients. We recommend that patients who show a delay over 3 minutes in $Neurocheck^{TM}$ test after topiramate initiation should be monitored for hypohydrosis.