• 한국식품영양과학회지
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• 제31권6호
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• pp.1112-1118
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• 2002

민들레의 추출물을 급여한 흰쥐에게 streptozotocin으로 당뇨를 유발하여 장내 미생물 균총에 미치는 영향을 구명하기 위하여 Wistar계의 이유한 웅성 흰쥐 64마리를 난괴법으로 8군으로 나누어 streptozotocin(55 mg/kg BW)과 식이 kg당 11.45g의 민들레가 함유되도록 부위와 분획별로 나누어 식이에 첨가하여 50일간 사육하였다. 당뇨-대조군의 총혐기성균은 14일간 증가하다가 당뇨로 인하여 감소를 나타내었으며 잎 추출물 급여시 50일에는 당뇨-대조군에 비하여 증가되었다. 뿌리에틸아세테이트 추출물 급여군은 당뇨-대조군에 비하여 총혐 기성균수가 많은 것으로 나타났다. 민들레의 잎과 뿌리의 추출물 급여초기인 14일의 총호기성균은 당뇨-대조군에 비하여 높았으나 35일에는 당뇨-대조군에 비하여 낮은 것으로 나타났으며 50일에 총호기성균수의 변화결과는 총혐기성균의 변화양상과 유사한 것으로 관찰되었다. 장내 미생물의 변화는 당뇨가 유발된 50일에 당뇨-대조군에 비하여 민들레 잎-열수 추출물 군과 일-에틸아세테이트 추출물군에서 Lactobacillus 증가가 현저하였으며, E. cofi 감소는 잎과 뿌리의 열수 추출물군과 에틸아세테이트 추출물군이 당뇨-대조군과 유사한 수준이며 특히 열수 추출물군의 E. coli억제효과가 관찰되었다. 본 실험 결과 민들레추출물이 당뇨유발된 흰쥐의 장내 미생물에 유익한 효과로 숙주의 감염에 대한 저항력이 있는 것으로 나타났다.

• IMMUNE NETWORK
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• 제6권3호
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• pp.145-153
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• 2006

Background: Tumor cell lysate has been considered as a preferential antigen source for the therapeutic dendritic cell pulsing. Our experiences with in vivo study with animal tumor model indicate the tumor cell lysate dependent differential effect of DC therapy. Our previous data show that MC38 lysate pulsed-DC induced stronger ag-specific immunity than CT26 lysate pulsed-DC in vitro. In this study we tried to reveal the mechanism for differential induction of ag-specific immunity of different colon cancer cell lysate pulsed-DCs. Methods: MC38 and CT26 cell lines were prepared as lysate by freezing-thawing procedure. Tumor cell antigenicity was confirmed by detecting the surface expression of MHC I/II & B7.1/2 molecules. IL-10, IL-12 and TGF-beta in the tumor cell lysate were detected by ELISA and the presence of heat shock proteins were analysed by western blotting. Results: The secretion of IL-10, a immune-inhibitory cytokine was about 470% higher in CT26 lysate than in MC38. Hsp 70 was detected only in the MC38 lysate but not in the CT26. On the other hand, Hsp 60 and 90 expression were not different in two colon cancer cell lysates. Conclusion: In two different colon cancer cell lysate, immune inhibitory IL-10 (higher in CT26) and Hsp70 (MC38 superiority) were differentially expressed. These data indicate that higher agspecific immunity induction by MC38 lysate pulsed-DC may due to the expression of hsp70 and lower secretion of IL-10, a immune-inhibitory cytokine than CT26 lysate. The significance of other cytokine and the surface marker expression will be discussed.

• 한국산림과학회지
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• 제83권4호
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• pp.521-530
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• 1994

재적식(材積式)은 보통 흉고직경과 수고의 함수로 표현되는데, 회귀분석(回歸分析)을 통해 정확도가 높은 식이 주로 채택되고 있다. 우리나라에서도 지금까지 흉고직경(D)과 수고(H)를 독립변수로 하는 지수식(指數式)($V=aD^bH^c$)으로 각 수종에 대한 일반(一般)재적식을 유도하고 있다. 본 연구에서는 강원도 지방내의 홍천, 정선, 명주, 원주, 영월지역에 대한 간곡선식(幹曲線式)을 지역별로 유도하고, 이 간곡선식의 회전체(回轉體) 적분(積分)을 통해 지역별 재적을 직접 추정할 수 있는 간곡선 및 재적식 모델을 마련하였다. 조제된 모델에 의해 지역별로 추정된 재적은 기존의 강원도 지방 소나무재적표에 의해 추정된 재적에 비해 정확도가 높았다. 또한 지역간곡선식에 의해 유도된 간곡선의 형태는 지역에 따라 서로 달랐으며, 특히 영월지역과 원주지역의 수간은 다른 지역에 비해 수간상부에서 가늘게 발달하는 것으로 나타났다. 이와같은 간곡선의 다양한 형태는 재적추정에 있어서도 지역간 차이를 유발하였다.

• 한국정보과학회논문지:시스템및이론
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• 제33권9호
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• pp.608-614
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• 2006

초고속 네트워크의 보편화와 하드웨어 및 서버 기술의 발달로 인해 대규모 고성능 분산 네트워크 중심의 IT 기반구조 구축이 사회 전반에 걸쳐 확대되고 있다. 이러한 IT 기반 구조에 대한 평가 척도는 매우 다양하게 제시될 수 있지만, 기반 구조라는 특성 상 생존성 평가는 매우 중요한 척도로 간주된다. 주어진 IT 기반 구조에 대하여 어느 정도의 생존성을 가지고 있는지 평가하는 것은, 무수한 IT 기반 구조들에 대한 보편적인 평가 척도를 제시하는 것일 뿐만 아니라 해당 평가결과를 토대로 한 추가 개선 작업을 통하여 더욱 생존성이 강화된 IT 기반 구조로의 발전을 보장해준다. 본 논문에서는 현재의 IT 기반 구조를 구성하고 있는 개별 구성요소들에 대하여 이미 구축해 놓은 방어메커니즘 데이타베이스(DMKB)를 토대로 하여, 전체 IT 기반 구조의 생존성을 평가하는 시스템을 제시한다.

• 종양간호연구
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• 제2권1호
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• pp.61-71
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• 2002

Gastric Carcinoma is very plentiful and significant disease in Korean community. The reason is that Gastric Carcinoma is not a simply finding disease with unclear symptoms for early detection. Early detection and early medical treatment of a cancer patient is an important instrument of reducing the mortility rate. The purpose of this study is to identify the effect of audiovisual information with videotape infulencing on knowledge and attitude of early detection of gastric carcinoma. The research design was a non-equivalent control group, pre-post test. The subjects of this study were 52 members of D-taxi drivers which was located in Pusan. The subjects were twenty six experimental group and twenty six control group. The experimental group was collected from January 15, 1999 to January 26, 1999. The control group was collected from the research was 28 minutes video program which was turning out the form of documentary on the based practical experience. And also the experimental tool was used measurung instrument which measured a dependent, variable throughout the consulatation of an percentage, average, standard deviation, ${\chi}^2-test$ and t-test using spss/pc program. The result of this research were as follows : 1)" The experimental group which was offered the video program, should be higher in knowledge of early detection of the gastric carcinoma than the control group" was supported. (t= -7.754, p=.000) 2) "The experimental group which was offered the video program, should be higher in attitude of the early detection of the gastric carcinoma than the control group" was supported. (t=-4.321, p=.000) Therefore, in conclusion, this study that the audiovisual information with videotape influencing on knowledge and attitude of early detection of gastric carcionma was very representational experience throughout the video of documentary form on the based practical experience was much effected the change of the knowledge and the attitude regarding to the early detection of the gastric carcinoma was verified.

• 한국농촌생활과학회지
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• 제8권2호
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• pp.111-117
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• 1997

In this study we tried to give a decision on propriety of working conditions, to present ideas on reducing work loads. and to grope for efficiency of agricultural works. For this we examined the actual conditions of working environment, farmer's clothes, working posture, working methods, working time, resting state, fatigue recovery methods during cultivating lettuce in the winter greenhouse. And Ive improved harmful factors that affect farmer's health by considering results of previous study and farmer's subjective sensation. And we measured, compared, and analyzed the farmer's work loads before and after improvement. The results of this study are as follows ; 1. According to examine the actual conditions of cultivating lettuce in the winter greenhouse, farmers have experienced physical and mental chronic fatigue on the basis of the hot and humid crops-centered working environment, the rough ground condition, inconsistent arrangement of working stand and sorter, heavy-weared habits. and unsuitable working posture. 2. When we improved harmful factors that affect farmer's health, conformed the positive effects on important work efficiency index such as heart rate, electromyovolume, body temperature, and microclimate inside clothing and work loads were decreased by improving the hot and humid working environment, eliminating the hillock and obstacles of working path. deliver way, arranging the working stand and sorter consistantly, decreasing the clothing weight, improving the working postures and methods as using assistant appliances, alloting the working time and sequence effectively and presenting the light gymnastic exercises and rest for fatigue restoration.

• 한국농촌생활과학회지
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• 제8권2호
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• pp.119-124
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• 1997

In this study we tried to give a decision on propriety of working conditions, to present ideas on reducing work loads, and to grope for efficiency of agricultural works. For this we examined the actual working conditions of cultivating welsh onion in the summer ground. And we improved harmful factors that affect farmer's health by considering results of previous study and farmer's subjective sensation. And we measured. compared, and analyzed the farmer's work loads before and after improvement. The results of this study are as follows ; 1. According to examine the actual working conditions of cultivating welsh onion in the summer ground, farmers have experienced physical and mental chronic fatigue on the basis of farmer's appel to eye - fatigue and sun - burned skin on hot working environment including excessive ultraviolet rays, the rough ground condition, inconsistent arrangement of working stand and sorter, heavy - weared habits, and unsuitable working posture. 2. When we improved harmful factors that affect farmer's health, conformed the effects on important work efficiency index such as heart rate, electromyovolume, body temperature, and microclimate inside clothing and work loads were decreased by eliminating the hillock and obstacles of ground, decreasing the clothing weight, using proper clothing appliances such as hat and sunglasses, controlling height of working stand and sorter suitably, improving the working postures and methods as using assistant appliances, alloting the working time and sequence effectively and presenting the light gymnastic exercises and rest for fatigue restoration.

• 한국콘텐츠학회논문지
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• 제15권12호
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• pp.378-386
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• 2015

본 연구는 물리치료사의 사회인구학적 특성이 물리치료 독립개원의 필요성 인식과 전문직업성에 어떠한 영향을 미치는지 알아보고자 실시하였다. 연구 방법은 2015년 서울 경기 지역의 물리치료사 253명을 대상으로 사회인구학적 특성과 전문직업성 척도를 설문조사하였다. 분석 결과, 물리치료사는 사회인구학적 특성에 상관없이 물리치료의 독립개원을 위한 법률 수정이 필요하다고 인식하고 있었다. 물리치료사의 전문직업성 평균은 보통 이상의 수준으로 높지 않았으나 근무기관에 상관없이 연령과 최종학력, 임상경력이 높고 관심분야에 따라 전문직업성이 높게 나타났다. 결론적으로 한국의 물리치료사는 물리치료 독립개원을 위한 법률 개정이 필요하다고 인식하고 있으나 아직 까지는 개정에 필요한 전문직업성은 높지 않았다.

• 대한교통학회지
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• 제32권6호
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• pp.615-627
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• 2014

본 연구는 비계층적 K-평균 군집분석을 이용하여 보행자사고와 토지이용특성에 따른 지방자치단체의 유형을 분류하고 유형별 보행자사고의 세부특성을 Mann-Whitney U검증과 Kruskal-Wallis 검증을 이용하여 분석한 다음 그 결과로부터 보행환경 조성사업에 대한 개선방안을 제안하였다. 지역은 행정시와 행정구를 제외한 기초지방자치단체를 기준으로 230개 시 군 구로 구분된다. 비계층적 K-평균 군집분석 결과 230개 지방자치단체는 유형 1-A(상업지가 상대적으로 우세한 도시형), 유형 1-B(주거지가 우세한 도시형), 유형 2(농촌형)로 분류되었으며, 지자체 유형별 보행자사고 차이 검증결과 9m 미만 생활형 도로의 보행자사고 발생율은 공통적으로 60% 이상으로 도시형에 비해 농촌형에서 발생할 비율이 더 높았다. 또한 유형별로 유형 1-B는 교차로 내 보행자사고 사상자수가 많고 횡단 중 사고 비율도 높은 반면 길가장자리구역 통행 중 보행자 사상자수 비율은 유형 2에 해당하는 농촌형이 가장 높았다.

• 한국식생활문화학회지
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• 제29권1호
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• pp.44-53
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• 2014

Various Korean healthy foods containing Deoduk were developed and standardized recipe. Sensory evaluations of Koreans and foreigners for these developed foods were performed by using the 5-point hedonic scale. The results of the sensory test on foods containing Deoduk were as follows: Deoduk bap (2.90~3.91), Deoduk seolgidduk (3.19~4.40), Deoduk gangjeong (3.00~4.60), riasted Deoduk with red pepper paste (2.73~4.20), Deoduk pine nut juice salad (2.40~3.96), and Seopsansam (3.91~3.81). Deoduk seolgidduk, developed by using a recipe for Sansambyeong which in a Chosun dynasty cook-book, was highly preferred by Africans, Japanese, and Koreans. In particular, all foreigners except Southeast Asians liked Deoduk gangjeong, and both Koreans and foreigners liked Seopsansam. Foreigners' experience of eating foods containing Deoduk was high at 'No' (68.9%), whereas Japanese (60.0%) had previous experience. Exactly 91.6% of Koreans responded 'Yes' to the question of whether or not Deoduk food is good for health, whereas the proportion of foreign respondents who said 'Yes' was 43.2%, 'No' was 5.4%, and 'I don't know' was 51.4%. Deoduk seolgidduk was preferred by Japanese, and most foreigners preferred Deoduk gangjeong and Seopsansam. Therefore, Deoduk could be developed as a healthy food for globalization of Korean food. However, as foreigners' awareness of Deoduk is low, we must positively promote the health function of traditional food ingredients and develop various menus suitable forforeigners' tastes for the globalization of Korean food.