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Case of Acute Hemolytic Transfusion Reaction due to Anti-Fya Alloantibody in a Patient with Autoimmune Hemolytic Anemia (자가면역용혈환자에서 항-Fya 동종항체에 의한 급성용혈성수혈반응 1예)

  • Choi, Seung Jun;Nah, Hyunjin;Kim, Yundeok;Kim, Sinyoung;Kim, Hyun Ok
    • The Korean Journal of Blood Transfusion
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    • v.29 no.3
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    • pp.320-327
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    • 2018
  • A 72-year-old man with general weakness visited the outpatient clinic of the hematology department. The patient had been treated under the diagnosis of autoimmune hemolytic anemia for 2 years. His hemoglobin level at the time of the visit was 6.3 g/dL, and a blood transfusion was requested to treat his anemia. The patient's blood type was A, RhD positive. Antibody screening and identification test showed agglutination in all reagent cells with a positive reaction to autologous red blood cells (RBCs). He had a prior transfusion history with three least incompatible RBCs. The patient returned home after receiving one unit of leukoreduced filtered RBC, which was the least incompatible blood in the crossmatching test. After approximately five hours, however, fever, chills, dyspnea, abdominal pain, and hematuria appeared and the patient returned to the emergency room next day after the transfusion. The $anti-Fy^a$ antibody, which was masked by the autoantibody, was identified after autoadsorption using polyethylene glycol. He was diagnosed with an acute hemolytic transfusion reaction due to $anti-Fy^a$ that had not been detected before the transfusion. In this setting, it is necessary to consider the identification of coexisting alloantibodies in patients with autoantibodies and to become more familiar with the method of autoantibody adsorption.

Epidural Abscess Caused by Eikenella corrodens in a Previously Healthy Child

  • Kim, Ye Kyung;Han, Mi Seon;Yang, Song I;Yun, Ki Wook;Han, Doo Hee;Kim, Jae Yoon;Choi, Eun Hwa
    • Pediatric Infection and Vaccine
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    • v.26 no.2
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    • pp.112-117
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    • 2019
  • Eikenella corrodens rarely causes invasive head and neck infections in immunocompetent children. We report a case of epidural abscess caused by E. corrodens in a previously healthy 13-year-old boy who presented with fever, headache, and vomiting. On physical examination upon admission, there was no neck stiffness, but discharge from the right ear was observed. Brain magnetic resonance imaging (MRI) revealed approximately 4.5-cm-sized epidural empyema on the right temporal lobe as well as bilateral ethmoid and sphenoid sinusitis, right mastoiditis, and right otitis media. During treatment with vancomycin and cefotaxime, purulent ear discharge aggravated, and on follow-up brain MRI, the empyema size increased to $5.6{\times}3.4cm$ with interval development of an abscess at the right sphenoid sinus. Burr hole trephination was performed, and foul-smelling pus was aspirated from the epidural abscess near the right temporal lobe. Pus culture yielded E. corrodens. Endoscopic sphenoidotomy was also performed with massive pus drainage, and the same organism was grown. The patient was treated with intravenous cefotaxime for 3 weeks and recovered well with no other complications. Therefore, E. corrodens can cause serious complications in children with untreated sinusitis.

Effects of Forest Healing Programs Using School Forests on Language Acquisition and Ego-resilience of Multicultural Background Students (학교 숲을 활용한 산림치유프로그램 활동이 다문화배경 학생들의 언어습득 향상과 자아탄력성에 미치는 영향)

  • Jang, Cheoul-Soon;Shin, Chang-Seob;Jang, Byung-Soon;Sharif, Md. Omar
    • Korean Journal of Environment and Ecology
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    • v.33 no.3
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    • pp.333-340
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    • 2019
  • As the number of students in the multicultural background grows, the interest in their education is also increasing. The purpose of this study is to investigate the effect of forest healing factors on the improvement of language ability and ego-resilience of students from multicultural families. We conducted an after-school forest healing program of ten male and ten female middle school students of a multicultural preparatory school located in ${\bigcirc}{\bigcirc}$-dong in Cheongju, Chungnam Province. The experiment consisted of a total of 12 weekly one-hour (60 minutes) programs from April 12, 2018 to June 26, 2018. The forest healing program is an activity that uses the various environmental factors that exist in the forest to increase the immunity of the human body and restore physical and mental health. To determine the difference in ego-resilience before and after the program, we conducted a paired t-test and analyzed with the SPSS 18.0 program. The results showed that the ego-resilience significantly improved in all sub-factors including the positive thinking ability, problem-solving ability, intimacy ability, emotional adjustment ability, and autonomic behavior ability (p<.001). The descriptive statistics of the language ability showed the improvement in writing errors, pronunciation errors, sentence errors, tense errors, and errors in research and connection. We expect the results of this study can be used as the basic data to improve ego-resilience and language acquisition ability of middle-entry children and students from multicultural families.

A Case Study on Performance Analysis of Antimicrobial Copper Film Attaching to Window for Responding to COVID-19 and Others (코로나19 등 대응을 위한 "유리창 부착용 항바이러스 동필름" 성능분석 사례연구)

  • Kim, Seong Je
    • Journal of Korean Society of Disaster and Security
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    • v.14 no.1
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    • pp.23-40
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    • 2021
  • In the era of the global coronal 19 pandemic, there is a risk of cross-infection in hospitals at the stage where treatments and vaccines are currently being developed and marketed, so individuals should enhance their acquired immunity and generalize their living systems by the performance of copper ions in the social environment. In order to prevent the spread of infection, the need for anti-bacterial film and its efficacy were analyzed through anti-viral performance tests based on research and development cases of worldwide and immemorial time. he Korea Construction Research Institute (KCL) has received anti-bacterial performance certification and anti-viral test scores from the "National Approval Performance Certification Agency." At the time, NCCP 43326 Human Corona virus (BetaCoV/Korea/KCDC03/2020), which was approved by the Centers for Disease Control and Prevention, was introduced to ensure that the activity rate of infected cells was satisfied in the anti-viral performance test. Anti-proliferation measures for the Corona 19 virus require a quality clinical trial study comparing the experimental group within the glass space where the antiviral copper film is constructed with the comparator of the same condition without copper film.

Characteristics of Management of Facilities and Healing Programmes for Forest Therapy (산림치유 시설의 운영 및 치유 프로그램 특성에 관한 연구)

  • Park, Cheon-Bo;Choi, Joon-Sung
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.22 no.2
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    • pp.468-474
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    • 2021
  • Forest healing is a natural method that utilizes various natural environmental factors of forests to enhance immunity and to heal mental and physical pathologies. The aim of this study is to suggest implications for the future development of forest healing by analyzing the characteristics of facilities and programs in 28 national and public healing forests in Korea. The concept of forest healing and programs is defined, and healing forests operating in Korea are classified by size. The facility operation and program characteristics of healing forests were analyzed according to size, and the results were used to suggest a future direction for the development of domestic forest healing. The research results are as follows. First, domestic healing forests have gradually been reduced in size since they were first opened in 2009, which is the cause of the competitive creation of local governments. Second, healing spaces, forest paths, and programs for the elderly, pregnant women and disabled should be expanded. Third, lodging programs need to be expanded, and subsidies for usage fees from local governments are required. Institutional supplementation should be provided to link program development and facilities and to clarify procedures and standards for forest healing facilities.

Qualitative Research on Mothers' Stress Level of Meal Preparation and Change of Food Consumption Pattern in Context of COVID-19 (코로나19 이후 가정 내 어머니의 식사준비 스트레스와 먹거리 소비패턴 변화에 관한 질적연구)

  • Lee, Yoonsun;Ryu, Sihyun
    • The Journal of the Korea Contents Association
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    • v.22 no.2
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    • pp.695-709
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    • 2022
  • This study examined the mothers' stress level as it related to meal preparation and a change in food consumption during the Covid-19 pandemic. I asked mothers about the difficulties related to meal preparation, changes in food consumption, and their interest in food and health information using in-depth research methods. As a result, food delivery and online food consumption have markedly expanded as eating out has decreased. Mothers tried to serve fresh food at home because they perceived delivery food as unhealthy. They stick to it more vigorously with their younger children. As the result of analysis on determinants of food consumption, their interest in organic food is higher when mothers' ages are younger with higher income. However, mothers with a low level of education tend to be uninterested in it. Therefore, the ages of the children and mothers, household income, and education levels all had an effect on food consumption behaviors.

Characterization of Weizmannia ginsengihumi LGHNH from Wild-Ginseng and Anti-Aging Effects of Its Cultured Product (산삼 공생 미생물 Weizmannia ginsengihumi LGHNH의 특징 및 배양물의 항노화 효능)

  • Minjung Kwon;Hyejin Lee;So Young Lee;Mu Hyun Jin
    • Microbiology and Biotechnology Letters
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    • v.50 no.3
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    • pp.414-421
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    • 2022
  • In this study, we isolated Weizmannia ginsengihumi LGHNH (KCTC 14462BP) from 30-year-old wild Panax ginseng C.A. Meyer and elucidated the characteristics of the isolated bacterium and its industrial potential as an anti-aging material. W. ginsengihumi LGHNH was investigated to produce indole-3-acetic acid (IAA), a plant growth-promoting hormone (1.38 ㎍/ml to 2.22 ㎍/ml). We also confirmed the existence of bioconversion activity via the comparison of the ginsenoside content before and after fermentation. As for the converted minor ginsenoside, Rg2(R), Rg4, Rg6, Rg3(S), Rg3(R), Rk1, Rg5, Rh1(R), Rk3 and Rh4 are known to have high bioavailability and various skin effects. We measured mitochondrial membrane potential and ATP biosynthesis to elucidate W. ginsengihumi LGHNH cultured product (WCP) as an anti-aging material. As a result, the mitochondrial membrane potential in HaCaT cells with UVB decreased to 39.3% compared to the unirradiated group, but was recovered to 57.3% and 58.1% by 0.001% (v/v) and 0.01% (v/v) WCP, respectively. In addition, we measured mitochondrial ATP biosynthesis. It decreased to 94.3% compared to the unirradiated group with UVB, but was recovered to 105.3% and 105.7% by 0.001% (v/v) and 0.01% (v/v) WCP.

Indonesian Halal Food Consumers' Perception, Attitude and Use of Ginseng and Red Ginseng Products (인도네시아 할랄식품 소비자의 인삼·홍삼제품에 대한 인식과 태도 및 이용 실태)

  • Park, Soojin
    • Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
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    • v.7 no.11
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    • pp.1-15
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    • 2017
  • Understanding muslim consumers' needs and behaviour is an essential process for strategic product development in the Halal food market. For our study on Indonesian consumers of Halal food, we conduct a survey of 200 Muslims residing in Indonesia on awareness of ginseng (G) and red ginseng (RG) products, eating experience, like or dislike reasons, cognitive level on the efficacy of G and RG products, purchase behaviors, satisfaction and repurchase intention through a web-based questionnaire methodology. This study reveals that 58 % and 51% of the participants indicate an awareness of G and RG products. In particular, awareness amongst medium- and high-income male consumers in their 20s and 30s is relatively high. This group of participants is also more likely to consume eat G and RG products for health promotion, refreshment, and disease prevention, and positively evaluated product efficacy. They are also aware of the efficacy claims of these products with regard to enhancement of immunity, fatigue, and stamina. While Indonesian Muslim consumers express satisfaction with the health claims, packaging specifications, and design of the products, they are dissatisfied with product types, price, taste, and aroma. The results also found that participants would recommend G and RG products to acquaintances, and are willing to purchase them in the future. Therefore, the segmentation of Halal-certified G and RG products for Muslim consumers and analysis on their product needs could be advantageous for strategic product development.

Malaysian Muslim's Awareness, Attitude and Purchasing Behavior of Ginseng and Red Ginseng Products (말레이시아 무슬림의 인삼·홍삼제품 인식과 태도 및 구매행동)

  • Park, Soojin
    • Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
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    • v.7 no.12
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    • pp.37-50
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    • 2017
  • This study was performed to understand Malaysian Muslims' awareness, attitudes and purchasing behaviour on ginseng (G) and red ginseng (RG) products. A survey of 200 Muslims residing in Malaysia was conducted on awareness, eating experience, preferences, cognitive efficiency of G and RG products, purchase behaviors and satisfaction through a online-survey methodology. Results shows that 50 % and 40% of the participants aware the G and RG products. In particular, awareness amongst female or married consumers is relatively high. Health promotion is the major reasons to consume eat G and RG products in this group of participants. However, the most frequently consumed type of G products was ginseng coffee, candies and chocolates, in their 40s and 50s or married consumers. Participants are also aware of the efficacy claims of these products with regard to improvement of fatigue, immunity and hypertension. While Malaysian Muslim consumers are satisfied with the health claims, convenience to purchase and tastes and aroma, they are dissatisfied with packaging specifications, price. Participants would intend to recommend G and RG products to relatives (82.6%), and are willing to buy them in the future (83.5%). Conclusively, there must be a clear interest and demands of Halal-certified G and RG products among Malaysian Muslims and it is deemed to need of strategic product development and marketing to enhance awareness of G and RG products in the future.

Characteristics of Functional Components of Red Ginseng Concentrate First Extracted at Low Temperature I - Focused on Ginsenoside - (저온에서 1차 추출한 홍삼농축액의 기능성분 특성 I - Ginsenoside 위주로 -)

  • Su Hyun Lee;Keon Shin;Seon Yeung Jo;Young Sig Park
    • Journal of Food Hygiene and Safety
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    • v.38 no.3
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    • pp.176-183
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    • 2023
  • The extraction and filtration of red ginseng with a mixed solvent of water and alcohol-a common processing method-and the production of a concentrate through heat treatment, such as steaming, leads to its hydrolysis or polymerization. Approximately 200 ginsenosides have consequently been detected in small amounts, in addition to the identification of the functions of approximately 30 major ginsenosides. This complicates the identification of the functionality of red ginseng and its efficacy, and has negative effects as a functional food, as the astringent taste becomes stronger with an increase in the number of extractions. The red ginseng concentrate was, therefore, extracted at a low temperature (less than 40 ℃) and processed to eliminate these negative aspects, with a specific focus on the characteristics of the functional components of ginsenosides.