• 보건세계
• /
• v.44 no.2 s.486
• /
• pp.8-13
• /
• 1997

겨울철이 되면 추위와 건조한 공기 및 혼탁한 실내공기로 인해서 상기도의 면역력이 떨어지므로 상기도염으로 고생하게 된다. 겨울철에 대표적인 상기도염으로는 감기와 인플루엔자가 있다. 감기는 여러가지 바이러스에 의한 상기도감염으로 발생하는 병으로 한의학에서는 호흡기 증산이 심할때는 풍해, 유행성일때에는 양감이라 부른다. 감기는 겨울철에 특히 기승을 부리지만 사실은 일년 내내 계속되는 상기도염으로 특히 노인층에서는 감기에 따른 합병증으로 문제가 될 수 있으므로 만병의 원인이라고도 불리우고 있다. 인플루엔자는 인플루엔자바이러스에 의한 상기도감염으로 한의학에서는 천행중풍(天行中風)이라 부르며 겨울철에 유행하는데 금년에는 96년 12월부터 인플루엔자 환자가 생기기 시작해 곧 인플루엔자 유행이 시작될 가능성이 높다.

• Korean journal of applied entomology
• /
• v.51 no.3
• /
• pp.245-253
• /
• 2012

Benzylinedeneacetone (BZA) is a bacterial metabolite which is synthesized by at least two entomopathogenic bacteria, namely Xenorhabdus nematophila and Photorhabdus temperata subsp. temperata. It has been shown to possess inhibitory effects on insect cellular and humoral immune responses as well as antimicrobial activities against various species of bacteria and fungi. However, its relatively high phytotoxicity, and nonsystematic effect have thus far prevented its development into an optimal pesticide. This study screened five different BZA derivatives in order to select an optimal compound, which would have relatively high solubility and low phytotoxicity while retaining sufficient degrees of the immunosuppressive and antimicrobial activities associated with BZA. Hydroxylation of the benzene ring of BZA was found to significantly suppress its immunosuppressive and antimicrobial activities. Transformation of the ketone of BZA by carboxylation also suppressed the inhibitory activities. However, a shortening of the aliphatic chain of BZA into acetate form (4-hydroxyphenylacetic acid: HPA) did not decrease the inhibitory activity. HPA also showed much less phytotoxicity against the hot pepper plant Capsicum annuum, when compared to BZA. This study identified an optimal BZA derivative, which exhibited relatively little phytotoxicity, but retained a high degree of inhibitory activity to suppress insect immune responses and antimicrobial activities against plant pathogens.

• Convergence Security Journal
• /
• v.1 no.1
• /
• pp.57-68
• /
• 2001

Computer security is considered important because of the side effect generated from the expansion of computer network and rapid increase of the use of computer. Intrusion Detection System(IDS) has been an active research area to reduce the risk from intruders. In this paper, the Hybrid Intrusion Detection System(HIDS) based biometric immuntiy collects and filters audit data by misuse detection is innate immune, and anomaly detection is acquirement immune in multi-hosts. Since, collect and detect audit data from one the system in molt-hosts, it is design and implement of the intrusion detection system which has the immuntiy the detection intrusion in one host possibly can detect in multi-hosts and in the method of misuses detection subsequently.

• The Korean Journal of Pesticide Science
• /
• v.13 no.2
• /
• pp.111-116
• /
• 2009

Juvenile hormone (JH) is an insect hormone mediating immature metamorphosis and adult reproduction. It also mediates immune responses to suppress hemocyte behavior, which is, however, activated by ecdysteroid. This study investigated an effect of a commercial pyriproxyfen (a JH agonist) formulation on a cellular immune response of the diamondback moth, Plutella xylostella, and analysed its mixture with Bacillus thuringiensis (Bt) in insecticidal potency. The commercial pyriproxyfen formulation significantly suppressed hemocyte-spreading behavior at low doses as did in pyriproxyfen technical grade. When the commercial pyriproxyfen formulation was mixed with Bt, Bt toxicity was significantly increased against P. xylostella larvae in laboratory. The mixture effect was then confirmed in field cultivating cabbage infested with P. xylostella larvae. The mixture showed a significantly enhanced mortality and reduced effective lethal time, compared to only Bt treatment.

• Microbiology and Biotechnology Letters
• /
• v.47 no.4
• /
• pp.509-514
• /
• 2019

We investigated the beneficial effects of Ecklonia cava by-product (ECB), a residual product obtained after polyphenol extraction from Ecklonia cava, on normal rats. Male Sprague-Dawley rats were divided into the following three groups: Control group (NC), received basal diet; ECB 0.1 group, received basal diet supplemented with 0.1% ECB for 21 days; ECB 0.5 group, received basal diet supplemented with 0.5% ECB for 21 days. The productivity, serum immunoglobulin level, expression levels of muscle-related genes, and cecal microflora were measured in all the treatment groups to evaluate the potential use of ECB as a feed additive. The ECB 0.1 group exhibited enhanced expression of Myod, Myog, and Igf1 genes, which increased the body weight of rats. Additionally, treatment with ECB increased the cecal Lactobacillus spp. counts and the serum immunoglobulin G levels in rats. Thus, ECB can effectively increase body weight and can be a potential feed additive for improving growth.

• Journal of Digital Convergence
• /
• v.11 no.1
• /
• pp.309-314
• /
• 2013

This study aimed to identify the effect of chronic mind-body function decline on health-related activities of daily living. Data collection was surveyed using interview and questionnaires by 148 subjects in a general hospital located in Seoul from June 8 to July 13, 2011. The results were as follows: First, based on exercise habit, patient group who do exercise regularly showed in male(26.7%) and female(22.7%), respectively. The risk ratio of it was 0.25 times. On the other hand, control group who do exercise regularly showed in male(42.2%) and female(31.8%), respectively. The risk ratio of it was 0.61 times. Secondly, the risk ratio of social factor in male was 45.18 times(p=.04) while the risk ratio of physical factor in female was 237.1 times(p=.001). In conclusion, to prevent declining of chronic mind-body function, it is necessary to solve stress through sound life rhythm maintenance, immunity enhancing food intake and continuous exercise.

• The korean journal of orthodontics
• /
• v.28 no.3 s.68
• /
• pp.441-452
• /
• 1998

The c-fos is known as neuronal marker of second neurons which is activated by noxious peripheral stimulation. To investigate the changes of c-fos el(pression in the trigeminal nucleus complex during tooth movement, immunohistochemical study was performed. Experimental rats(9 weeks old, 210 gm 21 rats) were divided into seven groups(normal, 1 hour group, 3 hour group, 6 hour group, 12 hour group, 1 day group,3 day group). Rats in the normal group were anesthesized without orthodontic force. Rats in the experimental groups were applied orthodontic force (approximately 30 gm) to upper right maxillary molar. Frozen sections of brain stem were immunostained using rabbit antisera. The changes of c-fos expression were observed with respect to rostrocaudal distribution, laminar organization, md duration of orthodontic force application. The study results were as follows $\cdot$The c-fos nuclei in the dorsal part were observed from ipsilateral transition zone of subnucleus interpolaris and subnucleus caudalis to $C_1$ cervical dorsal horn rostrocaudally. The maximal peak point was the rostral part of subnucleus caudalis. The greatest proportion of c-fos cells were located within lamina I and II. $\cdot$The c-fos nuclei in the dorsal Part were observed from the most caudal part of subnucleus interpolaris to the middle part of the subnucleus caudalis. $\cdot$The number of c-fos immunoreactive dot increased at 1 hour group, reached its maximum at the 3 and 6 hour groups, and showed a decreasing trend after 12 hours. These results imply that nociceptive stimulation caused by continuous orthodontic force might be modulated by transition zone of subnucleus interpolaris and subnucleus caudalis, subnucleus caudalis, $C_1$ spinal dorsal hem.

• Journal of fish pathology
• /
• v.30 no.1
• /
• pp.41-49
• /
• 2017

Probiotic principles can be applied in aquaculture for the purpose of growth and immunity stimulation, disease prevention and eventually better production performance. This study was to assess effects of combinations of microbes containing two Bacillus sp., plus one Lactobacillus sp. as the basal preparation (BSL-LAB), and additional Nitrosomonas sp. (nitrifying bacteria consortium, NBS) in olive flounder (Paralichthys olivaceus). The effects examined were growth parameters, hematologic parameters, innate immunity and pathogen challenge test. Fish were assigned to 4 treatments as Control (no probiotics), Group A (Bacillius and Lactobacillus to culture water), Group B (Bacillius and Lactobacillus both in water and feed), Group C (same as Group B with additional Nitrosomonas in feed). Fish were allocated to the above 4 groups, each group being composed of triplicate 30 fish, for a 7-week feeding in the laboratory. Positive effects were observed both in growth and pathogen sensitivity with all three probiotic combinations. Such effects were attributed to improved innate immune functions. This result indicates that the tested probiotic microbes are beneficial to olive flounder aquaculture.

• Journal of fish pathology
• /
• v.12 no.2
• /
• pp.73-81
• /
• 1999

To study the supplementaing effects of kugija, Lycium chinense, in commercial diet on the immune response of nile tilapia, Oreochromis niloticus, nonspecific immune responses were investigated. The activities of complement and lysozyme were higher in sera of the fish fed diet with kugija than control diet. The effects of kugija on vaccination of fish to Edwardsiella tarda were compared in three different vaccination methods after feeding kugija for ten weeks. Intraperitoneal injection and bath administration with formalin killed cells (FKC) and bath with extracellular products (ECP) after injection of FKC showed differences in immune responses of vaccinated fish. Bath administration with ECP after injection of FKC was more stimulated than any other methods in each of nonspecific and specific responses such as the activities of complement and lysozyme, antibody production and rosette forming cells. Moreover, cumulative mortality was significantly lower in the fish vaccinated with combination FKC and ECP after injection challenge with live E. tarda.

• Journal of Life Science
• /
• v.20 no.1
• /
• pp.82-89
• /
• 2010

This study was investigated to analyze the contents of flavonoid compounds and the effects of fermentation on the physiological activities of medical plants, also known as SanYa (SY). Antioxidative activity of the fermented SanYa (FSY) was measured by using DPPH radical scavenging and SOD-like activity. DPPH radical scavenging and SOD-like activity of FSY were 94.3% and 45.0%, respectively. Nitric oxide (NO) synthesis was increased 11 times through the addition of FSY. However, NO production of the macrophages RAW264.7 cells stimulated with lipopolysaccharide (LPS) was reduced to 56% through the addition of FSY. FSY showed fibrinolytic activity and indicated about 69.8% and 73.7% of xanthine oxidase and angiotensin converting enzyme inhibitory activities, respectively. These results suggested that FSY plays a significant role in fibrinolytic activity and have strong xanthine oxidase and angiotensin converting enzyme inhibitory activities.