• Title/Summary/Keyword: 면역결핍증후군

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Paradoxical Cryptococcal Meningitis Immune Reconstitution Inflammatory Syndrome in a Patient with Human Immunodeficiency Virus Infection: Matching Clinical Findings with MRI Findings (인간면역결핍바이러스 감염환자에서 역설적 크립토코쿠스 수막염 면역재구성 염증증후군: 임상 소견들과 자기공명영상 소견들의 대조)

  • Moon, Sungjun;Hahm, Myong Hun
    • Journal of the Korean Society of Radiology
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    • v.79 no.6
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    • pp.359-364
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    • 2018
  • There are two forms of cryptococcal meningitis immune reconstitution inflammatory syndrome (CM-IRIS): paradoxical CM-IRIS and unmasking CM-IRIS. It is important to distinguish paradoxical CM-IRIS and CM relapse because mortality of CM-IRIS is higher than that of CM without IRIS, and paradoxical CM-IRIS and CM relapse requires different treatment. We report a case of paradoxical CM-IRIS that well matches the clinical findings with MR findings during three years follow-up of a HIV infected patient and new MRI finding is also introduced to help distinguish them.

Good's Syndrome (Thymoma with Immunodeficiency) -A case report- (Good 증후군 치험 -1예 보고-)

  • Ryoo, Ji-Yoon
    • Journal of Chest Surgery
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    • v.39 no.1 s.258
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    • pp.85-89
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    • 2006
  • Good's syndrome (thymoma with immunodeficiency) is a rare cause of combined B and T cell immunodeficiency in adults. The clinical characteristics are increased susceptibility to bacterial infection and opportunistic viral and fungal infections. The most consistent immunological abnormalities are hypogammaglobulinemia and reduced or absent B cells. This syndrome should be treated by resecting the thymoma and replacing the immunoglobulin to maintain adequate IgG values. The author experienced one case of Good's Syndrome. The patient was a 64-year-old female who had a history of frequent sinopulmonary infection. Chest CT showed Pneumonia and anterior mediastinal mass and PCNB was taken and biopsy result was thymoma. She received thymectomy and replacement of immunoglobulin to control hypogammaglobulinemia.

Pleuropneumonectomy in a Patient With Acquired Immune Deficiency Syndrome and Lung Abscess (폐농양으로 진단된 후천성 면역결핍증후군 환자에서의 흉막전폐절제술)

  • 최성실;백효채;맹대현;정경영;장경희;김준명
    • Journal of Chest Surgery
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    • v.34 no.7
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    • pp.574-577
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    • 2001
  • A 54-year-old homosexual man was diagnosed as human immunodeficiency virus-1-positive in 1992. He was admitted to a tertiary hospital in March, 2000 because of right flank pain, fever and intermittent cough. A chest roentgenogram showed right-sided pleural effusion, and closed thoracostomy was performed for drainage Salmonella species and Escherichia coli were isolated from the pleural fluid. In spite of 6 weeks of antibiotic treatment, fever did not subside and the general condition gradually deteriorated, and under the diagnosis of lung abscess with empyema thoracis, right pleuropneumonectomy was performed. The general condition improved postoperatively until day 10 when he showed sudden change in mental status to stuporous and developed focal seizure. Brain CT showed multiple abscesses in right frontal and left frontotemporal lobes and he expired on postoperative day 14.

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Epidemiology of AIDS (AIDS의 역학)

  • 김정순
    • Korean Journal of Health Education and Promotion
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    • v.5 no.1
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    • pp.6-11
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    • 1988
  • AIDS, 즉 후천성면역결핍증은 인간면역결핍바이러스(Human Immunodeficiency Virus : HIV)라고 불리우는 바이러스에 의한 인간면역체계의 붕괴로 발생하는 질환이다. 1979년 최초로 새로운 임상적특징을 가진 증후군으로 의학학술지에 발표되어 의료계의 주목을 끌어오다가 1981년 봄 로스앤절레스에 있는 남성동성연애자에게 발생한 AIDS의 첫 예가 보고되어 본격적 연구가 시작되었다.

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Immune Reconstitution Inflammatory Syndrome-Like Reaction During the Treatment of Pneumocystis jirovecii Pneumonia in an Infant With Severe Combined Immunodeficiency

  • Ching-Yu Lin;Sung-Min Lim;Soo-Yeon Kim;Seung-Min Hahn;Jong-Gyun Ahn;Ji-Man Kang
    • Pediatric Infection and Vaccine
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    • v.31 no.1
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    • pp.130-135
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    • 2024
  • The effectiveness of corticosteroids in preventing immune reconstitution inflammatory syndrome in non-human immunodeficiency viruses Pneumocystis carinii pneumonia (PCP) patients, such as severe combined immunodeficiency (SCID) patients, is controversial. We experienced a paradoxical reaction during severe PCP treatment in a SCID infant, which responded well to adjuvant corticosteroids.

A Case of Diffuse Infiltrative Lymphocytosis Syndrome Associated with Human Immunodeficiency Virus Infection (사람면역결핍바이러스 감염에 동반된 미만성 침윤성 림프구 증가 증후군 1예)

  • Kwon, Sun Ok;Park, Won Wo;Lee, Hyun Kyung;Lee, Sung Soon;Kang, Youn Kyung;Lee, Young Min;Lee, Hyuk Pyo;Kim, Joo In;Choi, Soo Jeon;Yum, Ho Kee
    • Tuberculosis and Respiratory Diseases
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    • v.61 no.3
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    • pp.289-293
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    • 2006
  • Diffuse infiltrative lymphocytosis syndrome is an autoimmune syndrome that is characterized by the oligoclonal expansion of CD8+ T-lymphocytes in response to human immunodeficiency virus (HIV) antigens. The clinical manifestations include bilateral enlargement of the parotid glands, lymphocytic interstitial pneumonitis, lymphocytic hepatitis, neurological involvement and systemic lymphadenopathies. In addition to a positive HIV test, the diagnostic histopathological findings are CD8+ T-lymphocytic infiltrations in the lymphnodes, liver, lung, muscle and the salivary or lacrimal glands without granulomatous or neoplastic involvement. We report a case of pulmonary involvement of diffuse infiltrative lymphocytosis syndrome that was associated with a human immunodeficiency virus infection.

AIDS 환자의 신경인지기능 장애

  • Nam, Yun-Yeong
    • RED RIBBON
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    • s.72
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    • pp.9-11
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    • 2006
  • 후천성 면역 결핍 증후군(AIDS, Aquired Immune Deficiency Syndrome)과 사람 면역결핍 바이러스 (HIV, Human Immunodeficiency Virus)관련 질환은 1981년 처음 AIDS가 보고된 이래 전 세계적으로 인류의 건강을 위협하고 있는 공중보건학적 문제이다. 그동안 HIV/AIDS 관련 질환에 대한 치료들은 주로 감염 경로 차단 및 관련된 내과적 질환의 치료에 초점이 맞추어져 왔다. 그러나 AIDS 환자 본인뿐만 아니라 가족, 치료진들은 흔히 HIV 감염으로 인한 심리적인 어려움에서부터 HIV 전파 위험을 높이는 물질 오남용 문제, 우울증, 치매 같은 전형적인 정신과 질환 및 자살에 이르기 까지 다양한 종류의 정신건강 상의 문제들에 자주 직면한다. 이와 같은 신경정신과적 문제들은 치료 결과나 예후, 삶의 질 등에 영향을 미칠 수 있기 때문에 환자의 가족들은 AIDS로 인한 정신과적 질환이나 현상들에 대해 잘 이해하고 적절하게 대처할 필요가 있다.

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Development of quality of life with WHOQOL-HIV BREF Korean version among HIV patients in Korea (후천성면역결핍환자의 삶의 질 측정을 위한 한국판 WHOQOL-HIV BREF 개발)

  • Lee, Won Kee;Kim, Shin-Woo;Kim, Hye-In;Chang, Hyun-Ha;Lee, Jong-Myung;Kim, Yoon-Joo;Lee, Mi-Young
    • Journal of the Korean Data and Information Science Society
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    • v.25 no.2
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    • pp.337-347
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    • 2014
  • There is no known publication about assessment of quality of life (QOL) in Korean HIV patients. We aimed to assess the QOL of HIV patients. We developed Korean version of the WHOQOL-HIV BREF (short forms of WHOQOL-HIV, 31 questions with 6 domains). Survey data from 220 HIV-positive adults were obtained in 14 centers in South Korea. Male were dominant (202/220, 91.8%). Mean age was $40.6{\pm}12.1$. Mean CD4+ T-cell count was $414.9{\pm}226.6/ml$. Overall of WHOQOL-HIV BREF were $53.2{\pm}14.9$ (perfect score=100) (Cronbach's ${\alpha}$ = 0.942). It is similar score comparing to another country (Portugal: 54.75/100, measured by WHOQOL-HIV). Correlations of WHOQOL-HIV BREF score with patients' subjective QOL and with subjective satisfaction were 0.747 (p <0.01) and 0.651 (p <0.01), respectively. WHOQOL-HIV BREF have internal reliability. There is in need of monitoring for QOL of HIV patients in the clinical practice and trials. This survey tool could be used to assess the effect of intervention. Additionally, comparison across countries would be possible and promising.

DENTAL MANAGEMENT OF LEUKOCYTE DEFICIENCY IN A CHILD WITH SEVERE ORAL INVOLVEMENT (백혈구 접착 결핍 증후군 환아의 치과적 처치)

  • Kim, Hyun-Jin;Lee, Nan-Young;Lee, Sang-Ho
    • The Journal of Korea Assosiation for Disability and Oral Health
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    • v.3 no.1
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    • pp.26-30
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    • 2007
  • Leukocyte adhesion deficiency(LAD) is a rare autorecessive defect of phagocytic function resulting from a lack of leukocyte cell surface expression of ${\beta}_2$ integrin molecules(CD 18) that are essential for leukocyte adhesion to endothelial cells and chemotaxis. As a results, patients with LAD suffer from severe bacterial infections and impaired wound healing. A small number of patients with leukocyte adhesion deficiency-1 have a milder defect, with residual expression of CD18. These patients tend to survive beyond infancy; they manifest progressive severe periodontitis, alveolar bone loss, periodontal pocket formation, and partial or total premature loss of the primary and permanent dentitions. In this report, we report on a 7 year old girl with severe oral involvement. The most import focus should be to control infections to reduce the risk for future infection.

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