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A Case of Diffuse Infiltrative Lymphocytosis Syndrome Associated with Human Immunodeficiency Virus Infection  

Kwon, Sun Ok (Department of Internal Medicine, Seoul Paik Hospital, Inje University)
Park, Won Wo (Department of Internal Medicine, Seoul Paik Hospital, Inje University)
Lee, Hyun Kyung (Department of Internal Medicine, Seoul Paik Hospital, Inje University)
Lee, Sung Soon (Department of Internal Medicine, Seoul Paik Hospital, Inje University)
Kang, Youn Kyung (Department of Pathology, Seoul Paik Hospital, Inje University)
Lee, Young Min (Department of Internal Medicine, Seoul Paik Hospital, Inje University)
Lee, Hyuk Pyo (Department of Internal Medicine, Seoul Paik Hospital, Inje University)
Kim, Joo In (Department of Internal Medicine, Seoul Paik Hospital, Inje University)
Choi, Soo Jeon (Department of Internal Medicine, Seoul Paik Hospital, Inje University)
Yum, Ho Kee (Department of Internal Medicine, Seoul Paik Hospital, Inje University)
Publication Information
Tuberculosis and Respiratory Diseases / v.61, no.3, 2006 , pp. 289-293 More about this Journal
Abstract
Diffuse infiltrative lymphocytosis syndrome is an autoimmune syndrome that is characterized by the oligoclonal expansion of CD8+ T-lymphocytes in response to human immunodeficiency virus (HIV) antigens. The clinical manifestations include bilateral enlargement of the parotid glands, lymphocytic interstitial pneumonitis, lymphocytic hepatitis, neurological involvement and systemic lymphadenopathies. In addition to a positive HIV test, the diagnostic histopathological findings are CD8+ T-lymphocytic infiltrations in the lymphnodes, liver, lung, muscle and the salivary or lacrimal glands without granulomatous or neoplastic involvement. We report a case of pulmonary involvement of diffuse infiltrative lymphocytosis syndrome that was associated with a human immunodeficiency virus infection.
Keywords
Diffuse infiltrative lymphocytosis syndrome; HIV; CD8+;
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