• Proceedings of the KOR-BRONCHOESO Conference
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• 1996.04a
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• pp.89-89
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• 1996

CS gas(0-chlorobenzylidene malononitrite)가 우리나라 및 구미 각국에 시위진압과 군 화생방 교육에 널리 사용되고 있다. 이 CS gas는 인체에 자극적인 독성물질로 작용할 수 있다고 알려져 있으나 이비인후과 영역에 미치는 영향에 대하여는 보고가 드물어 CS gas 폭로에 의해 먼저 장애를 입을 것으로 생각되는 기관점막의 구성세포들의 변화를 관찰하기 위하여 실험동물을 사용하여 실험에 임하였다. 실험에 사용되는 실험동물은 150gm 내외의 Sprague-Dawley계 흰쥐로 대조군 5마리, 실험군 24마리를 사용하였으며 실험에 사용한 CS gas는 한영화학 CO.에서 제조한 분말형 CS gas를 사용하였다. 실험방법은 1㎥ 용적의 플라스틱 chamber에 CS분말을 투입한 후 실험동물을 넣어 CS gas를 흡입시킨 후 12시간, 1일, 3일, 5일이 경과한 후 희생시켜 기관점막의 변화를 관찰한 결과 다음과 같은 결과를 얻었다. 1. CS gas 흡입후 12시간이 경과한 흰쥐의 기관은 상피층이 증가되었고 위중층상피가 중층편평상피로 변화되었다. 2. CS gas 흡입후 1일 경과후는 기관상피층이 현저하게 감소되었다. 3. CS gas 흡입후 3일 및 5일 경과후 기관점막은 대조군의 것과 같이 거의 정상화되었다.

• Proceedings of the KOR-BRONCHOESO Conference
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• 1996.04a
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• pp.88-88
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• 1996

선천성 또는 외상등에 의한 후천성 기도 협착의 치료는 아직도 어려운 문제중 하나로서 해결하여야 할 많은 과제를 내포하고 있다. 특히 안정되고 유연한 구조적인 골격과 함께 호흡성상피로 피복되는 기관점막은 기관기능 보존에 있어 필수적 조건이다. 저자들은 현재까지 보고자에 따라 견해 차이가 있는, 이식연골막 및 이식점막의 운명에 대하여 시기에 따른 형태학적 변화를 관찰하고자 하였다. 즉 저자들은 혈행성 복합피판의 형태로 이식한 점막에 일어나는 변화를 형태학적으로 연구하였으며, 대조군으로는 혈행이 유지되지 않는 유리이식(free graft)으로 구성된 복합피판을 이용하였다. 또한 면역조직화학적 염색을 통해 이식 초기에 일어나는, 이식점막과 결손부 주변조직사이의 재생능의 차이를 비교하고자 하였다. 토끼 40마리를 두 군으로 나누어 각 군당 20마리씩으로 하였으며 술후 각각 2주, 4주, 6주 및 8주에 기관에 이식한 피판을 조직학적으로 분석하였다. 섬모의 재생상태는 주사현미경을 통해 관찰하였으며 각 군당 4마리의 토끼를 술 후 1일과 2일에 Brdu-Anti Brdu로 염색하여 결손된 점막의 주변부와 이식한 점막사이의 재생능이 복합피판의 구성에 따라 어떤 차이가 있는지 알아보았다. 1. 혈행성의 복합피판으로 구성된 구강점막은 원주상피로 화생(metaplasia)하는 경향을 보였으나 유리 연골막에 부착한 구강점막에서는 괴사가 진행되면서 주위의 점막에서 성장해 들어가는 양상을 보였다. 2. Brdu-Anti Brdu 염색의 결과, 복합피판의 구성에 따라 이식점막과 주위 기관상피의 염색양상에 유의한 차이를 나타내었다.

• Journal of Korea Game Society
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• v.13 no.1
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• pp.41-48
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• 2013

In general, the predator-prey model has been studied as a model of struggle for existence in a ecosystem. While conventional papers have focussed on the population change of the predator-prey, this paper focused on controlling the energy needed for the predator to pursue the prey. For simplification, assume the environment which there are only single predator and prey. Based on the environment, a certain amount of energy needed for a predator to pursue the prey was suggested on a basis of physical theories and also the used energy model was suggested on a basis of the simulation. From experiments, it was proven that the suggested energy models were appropriate for natural pursuit.

• Proceedings of the Korea Information Processing Society Conference
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• 2018.10a
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• pp.833-835
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• 2018

최근 돼지의 상태 및 행동을 분석하기 위하여 카메라를 이용한 돈사 내 돼지에 대한 감시 시스템에 관한 연구가 활발히 진행되고 있다. 특히, 대부분의 국내 돈사는 돼지를 밀집 사육하는 방식이기 때문에 돼지의 겹침이 빈번하게 발생한다. 돼지들 간 겹침이 발생하게 되면 한 마리의 돼지로 인식하는 문제가 있기 때문에 개별 돼지의 탐지 및 추적이 불가능하다. 본 논문에서는 깊이 정보 영상을 이용하여 겹침 돼지를 탐지하고 개별 돼지로 특정 하는 방법을 제안한다. 즉, 임계 값을 설정하여 돼지와 배경을 분리함으로써 돼지들의 영역을 탐지하고, 탐지된 돼지들의 영역 크기를 비교하여 겹침 돼지를 탐지한다. 이후 탐지된 겹침 돼지의 깊이 정보를 이용하여 겹침 돼지를 두 마리의 돼지로 특정한다. 실험 결과, 겹침 돼지를 탐지하였고 탐지된 겹침 돼지에 대하여 각각 서 있는 돼지와 누워 있는 돼지로 특정 하였다.

• Parasites, Hosts and Diseases
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• v.31 no.4
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• pp.375-378
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• 1993

The prevalence of Intestinal parasite Infections In Inhabitants at the reaches of the Hantan River, Chorwon-gun, Korea, was observed from August 12 to September 14, 1993. Of 465 people observed by cellophane thick smear and formalin-ether concentration method, 2 Ascots lumbricoides (unfertilized), 1 Trichwis Dichturn, 39 Clonorchis sinensis and 16 Metagonimus egg positive cases were found. After treatment, the Metogonimus egg positive cases passed out flukes of Metogonimus Mlyata type. Of 68 fish caught In the Hantan River, 14 (20.6%) were Infected with metacercanae of Metogontmn, while no metacercana of C. sinenis was found. At this area, soul-transmitted nematodes are very low, but clonorchlasis and metagonlmlasis are prevalent by modernate endemicity.

• Parasites, Hosts and Diseases
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• v.32 no.3
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• pp.201-204
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• 1994

Echinostomiasis is an endemic intestinal trematodiasis of humans in Korea We observed a human case of Echinostomn honense infection who had ulcerations on the duodenal mucosa. A 55-year old man living in Hamyang-gun, Kyongnam, complained of epigastric pain with hematemesis In April 1994. Endoscopy revealed lesions of early gastric cancer and duodenal ulcerations. A penetrating parasite into the duodenal mucosa was picked out, and identified as E. honense. As the patient was treated 10 praziquantel 10 mg/kg single dose,3 more E. hofene and 7 Metogonimw worms were recovered. This case demonstrates that echinostomiasis causes gross ulcerations in the duodenum.

• Parasites, Hosts and Diseases
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• v.31 no.4
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• pp.341-346
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• 1993

Seasonal distribution of chigger mites in the Kangwha Island and Yongjong Island was studied during the period of October 1992-August 1993. From 42 field rodents collected, 1,290 chiggers were obtained and 8 species of 4 genera were identified. In the Kanghwa Island, Leptopombidium pallidum was the predominant species through all seasons with the percentage of 93.0%. Whereas, In the Yongjong Island, L. palpale was the predominant species with the percentage of 38.4% and L. pnllidum was not found.

• The korean journal of orthodontics
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• v.33 no.2 s.97
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• pp.91-102
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• 2003

This study was performed to investigate the effect of immediate orthodontic force on soft md hard tissues surrounding C-Palatal $Plate^{TM}$ in beagle Dog. Immediately after this appliance was implanted on the midpalate of 4 adult beagle Dogs, 400gm continuous orthodontic force was applied. Experimental animals were euthanized at 8weeks, 18weeks, and 22weeks (including post-removal healing time of 4weeks), and a control animal was euthanized at 8weeks after implantation without orthodontic force application. The appliance and the surrounding tissue were studied radiographically, macroscopically, and histologically. The results were as follows: 1. The lateral radiographs taken after euthanasia showed very slight displacement of the vortical plate in the experimental animals, compared with the control animal. Mobility test of all animals confirmed primary stability without any increase of mobility during experimental period. 2. No pathologic changes were found in the healing condition of covering soft tissue and bone-screw interface in experimental animals as well as a control animal. 3. Osseointegration was achieved in the bone-screw interface in 8weeks after implantation and the amount of osseointegration increased in 18weeks. There was little difference of osseointegration between the compression side and the tension side. 4. In the marginal bone area, slight bone apposition and resorption were found regardless of compression and tension side, while there was no change in the control animal. 5. Both 8week-animal and 18week-animal showed the new bone apposition along the surface of screws which were perforated into the nasal cavity, while the control animal showed no change. 6. After 4weeks of plate removal, the covering epithelium was repaired intactly, while the connective tissue showed loose and irregular rearrangement and the connective tissue capsule remained. The C-Palatal $Plate^{TM}$ manifested sufficient anchorage capacity in the context of histological study as well as clinical outcomes, when immediate orthodontic force was applied after implantation.

• Clinical and Experimental Pediatrics
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• v.46 no.9
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• pp.876-882
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• 2003

Purpose : To find out the myocardial protective effect of cardioxane for the myocardial damage by doxorubicin. Methods : Using Eighteen rabbits(2.0-3.2 kg), doxorubicin($30mg/m^2$) was injected intravenously once a week in group I(12 rabbits) and cardioxane($600mg/m^2$) was injected at 20-30 minutes before doxorubicin administration in group II(6 rabbits). After this, we operated on the rabbits when the total cumulative dose of doxorubicin was reached at 210, 240, 270 and $300mg/m^2$ and observed the degree of myocardial damage with light and electronic microscope. Results : In group I, rabbits with less than $210mg/m^2$ of total cumulative dose of doxorubicin, there was no definite myocardial damage but with $240mg/m^2$, focal degenerative change was observed and with $300mg/m^2$, severe degenerative change was detected with light microscopic examination. With electronic microscope, rabbits with less than $180mg/m^2$ of total cumulative dose of doxorubicin in group I, there was no evidence of myocardial damage. In $210mg/m^2$, focal degenerative change was detected. With $240mg/m^2$, degenerative change was much more advanced and with $300mg/m^2$, severe degenerative change was detected. In group II, no definite myocardial damage was observed even though the total cumulative dose of doxorubicin reached $300mg/m^2$, but with $360mg/m^2$, there was a focal area where myocardial fibers were somewhat decreased, but it's difficult to say whether these decrement were due to adriamycin in the electronic microscopic examination. Conclusion : Cardioxane have a good protective effect for the doxorubicin induced cardiomyopathy and it will be used safely in pediatric cancer patients.

• The Korean Journal of Physiology
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• v.2 no.1
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• pp.79-88
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• 1968

For the purpose of assessing the influence of the mamillary bodies on the general activity and stress response, mamillary body·damaged rats(mamillary body group), operated control rats, and normal control animals were prepared and 2 experiments were carried out. The mamillary bodies. were damaged electrolytically by passing 0.3 ma d.c. current through stereotaxically implanted electrodes. The operated control group received the same treatment except passage of current. In the 1st experiment, each subject belonging to the mamillary body group .(9 rats) or the operated control group (13 animals) was put individually into an activity cage across which an infrared beam traversed. The number of beam interruptions by the movement of the subject in the cage was. recorded hourly for 48 hours and was regarded as an index of general activity. In the 2nd experiment, each of the mamillary body group (52 animals), the operated control group (45 rats), and the normal control group (37 animals) was further divided into 4 subgroups and the adrenal ascorbic acid content of one of the 4 subgroups was measured before, another subgroup immediately after, a third subgroup 2 hours after, and the remaining subgroup 4 hours after termination of a cold stress ($-10^{\circ}C$ for 1 hour). Following results were obtained: 1. Though the total activities in 48 hours of the mamillary body group and the operated control group were not significantly different, the activities of the malnillary body group for a few hours. at the beginning of the measurement and also in the evenings of both the 1st and the 2nd experimental days were significantly greater than those of the operated control group. 2. Judged by the significant reduction in adrenal ascorbic acid content, the stress response of the mamillary body group was as marked as that of the operated control or the normal control group-immediately after termination of cold exposure. Recovery from the stress was accelerated significantly in the mamillary body group and insignificantly in the operated control group compared with that of the normal control group, the intergroup difference of the former two groups being insignificant. It was inferred from the above results that the mamillary bodies may exert an inconspicuous inhibitory influence upon the central mechanism of general activity, and that the mamillaryies bodies may not be the main seat of the stress mechanism, although more works are desirable to confirm the results.