• Journal of Life Science
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• v.29 no.11
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• pp.1192-1199
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• 2019

The intention of this study was to confirm the possible use of an ethanol extracts of Nelumbinis Rhizomatis Nodus (NRN) as a cosmetic material. To this end, we extracted NRN with 70% ethanol and performed biological activity evaluation of whitening efficacy and wrinkle reduction. We performed cellular tyrosinase inhibition and melanin contents assay to check the whitening activity of NRN and carried out a toxicity evaluation of NRN via an MTT assay and the amounts of associated proteins that affect melanin production in a melanoma cell line (B16F10). And collagenase inhibitory assay was performed for the evaluation of anti-wrinkle of samples. In addition, a toxicity evaluation using an MTT assay and matrix metalloprotease (MMP-1) and procollagen synthesis inhibition by NRN were evaluated in a fibroblast cell line (CCD-986sk). Western blot results for the whitening activity evaluation revealed that the levels of two proteins related to melanin production, tyrosinase-related protein-1 (TRP-1) and tyrosinase-related protein-2 (TRP-2), were decreased in a dose-dependent manner. Moreover, collagenase inhibition activity at a concentration of $500{\mu}g/ml$ NRN by measuring epigallocatechin-3-gallate (EGCG) was increased by more than 80% compared to the control group. Meanwhile, procollagen synthesis was reduced by 68.8% in the UVB-induced CCD- 986sk cells group whereas collagen synthesis recovered by 80.2% with $25{\mu}g/ml$ NRN. The MMP-1 expression rate showed 20.2% reduction at $25{\mu}g/ml$. The results of the experiments verified the whitening and wrinkle suppression effects of NRN and confirmed that it could be used as a safe natural cosmetic material in the future.

• Proceedings of the Plant Resources Society of Korea Conference
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• 2019.10a
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• pp.36-36
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• 2019

정향풀[Amsonia ellipotica (Thumb.) Roem. & Schult.]은 5월에 백색의 취산꽃차례로 개화하여 관상가치가 높다고 판단되나, 전국에 자생지가 10곳 미만이며 한국적색목록에 위기종(EN)으로 평가되어 체계적인 번식 및 재배법 개발이 요구된다. 본 연구는 유전자원보전 및 신 관상소재로 개발 가능한 정향풀의 효과적인 육묘법을 확립하고자 수행되었다. 실험재료는 유용식물증식센터에서 분양받은 종자를 사용하였으며, 파종용기(72, 105 및 128구 트레이), 파종립수(셀 당 1, 2 및 4립), 토양종류(원예상토 단용 및 중화 피트모스와 펄라이트를 3:1 또는 4:1로 혼용), Hyponex[미분(6.5-6-19)] 추비농도(0, 250, 500 및 $1000mg{\cdot}L^{-1}$) 및 차광정도(0, 55 및 75%)를 달리하여 2019년 4월 20일부터 8주 동안 육묘하였다. 연구의 공통사항으로 종자를 $500mg{\cdot}L^{-1}$ $GA_3$에24시간 침지한 다음 원예상토를 충진한 105구 트레이에 셀 당 1립씩 파종하였으며, 이후 2, 4주차에 $500mg{\cdot}L^{-1}$ Hyponex를 엽면시비하였다. 연구의 결과, 파종용기는 셀 당 용적량이 많을수록 초장, 경직경, 엽수, 지상부 및 지하부 생체중이 증가하는 경향이었다. 파종립수에 따른 생육은 1립 파종 시 가장 우수하였으나, 2립 파종한 묘의 개체 당 생체중이 비교적 양호함에 따라 트레이 상 풍성한 볼륨감을 나타내었다. 추비처리의 농도가 증가할수록 유묘의 생육이 증가하는 경향이었으며, $1000mg{\cdot}L^{-1}$ 처리구에서 초장, 경직경, 엽수 및 생체중이 유의적으로 높았다. 한편 차광처리 시 차광정도에 관계없이 경직경, 엽수, 마디수 및 지상부 생체중이 유의적으로 감소하였다. 따라서 정향풀은 용적량이 큰 72구 트레이에 원예상토를 충진한 다음 셀 당 2립씩 파종하여 차광하지 않은 양지에서 Hyponex $1000mg{\cdot}L^{-1}$로 추비하는 것이 관상목적으로 육묘하기 위한 효과적인 재배법으로 판단된다.

• The Journal of Korean Philosophical History
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• no.58
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• pp.245-278
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• 2018

The paper has focused on examining the sense of educational process in the light of Xugua zhuan[序卦傳], the Sequence of the Hexagrams as one among Ten Wings in I Ching, particularly on the 11 Iching-hexagrams from ch'ien[乾] to t'ai[泰]. The process involved in this part of the Book of Change can be recognized as both the micro and macro levels, which can eventually leads us to construct the circular system of thought[環相型]. This gives us a possibility to consider the values of education beyond the dualism such as intrinsic and extrinsic as well as traditional and progressive ones. Particularly some crucial defects from child-centered education have been critically examined so that the concept of education can be taken seriously in the light of the teacher-side. Thus this provides us a necessity to dub 'education' as '敎育', not as '兒育' in the Oriental context. As shown in the paper, the cosmic dual forces of I Ching also enables us to dissolve some conflicts arisen in the educational welfare system and situations, and then shows us why we should respect for the teachers' stances though we have to consider the interests of children to be educated. Thus we need to re-examine the content of the Book in the link with the Western systems of educational theory.

• (The)Study of the Eastern Classic
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• no.33
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• pp.305-334
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• 2008

This paper is intended to present the philosophical thoughts of Yu Won-Ji who was one of famous scholars in The School of Toegye. He criticized Yi I(Yulgok) and Jang Hyeon-Gwang(Yeohyeon) because they regarded Li and Ch'i as one. Yi was considered an actual founder of their theoretical and political rival party called the School of Yulgok. Jang also refused to accept Toegye's theory and had developed his own theory, which emphasized the unity of Li(principle) and Ch'i(material force). Therefore Yu might well exclude Yi I(Yulgok) and Jang Hyeon-Gwang and criticize their theories severely. First, he was convinced that Toegye's doctrine(Li-Gi-Ho-Bal-Seol) was a orthodox theory accurately succeeding to Jhu Xi's learning. Secondly, he criticised Yi I(Yulgok) for looking upon Li and Ch'i as one thing. Thirdly, he regarded Jang's doctrine as same with Yulgok's. Fourthly, he thought it is necessary to criticize Jang's theory in order to preserve Toegye's learning and establish the theoretical identity of the Toegye School.

• Journal of Oriental Neuropsychiatry
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• v.32 no.1
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• pp.1-11
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• 2021

Objectives: To investigate the prevalence of acute stress disorder (ASD) and post-traumatic stress disorder (PTSD) in patients with traffic injuries. In addition, PTSD patients was classified using 'pattern identification for jing ji and zheng chong'. Methods: Questionnaires such as the primary care PTSD screen for DSM-5(PC-PTSD-5), Korean version of PTSD checklist-5 (PCL-5-K), and the instrument of pattern identification for jing ji and zheng chong were conducted on 195 patients within 3 days to 1 year after traffic accidents. Patients were recruited from six medical institutions. Collected data were used to determine the prevalence of acute stress disorder and post-traumatic stress disorder. Results: On PC-PTSD-5, the prevalence was 39.1% for ASD and 50% for PTSD. On PCL-5-K, the prevalence was 20.4% for ASD and 29.3% for PTSD. Satisfying both PC-PTSD-5 and PCL-5-K, the prevalence was 18.2% for ASD and 25.8% for PTSD. As a result of pattern identification for jing ji and zheng chong, 'weakness of heart and gall bladder type' accounted for the highest proportions in both ASD and PTSD groups. Conclusions: In this study, the prevalence was 39.1% for ASD and 50% for PTSD by PC-PTSD-5. Satisfying both PC-PTSD-5 and PCL-5-K, the prevalence was 18.2% for ASD and 25.8% for PTSD. Further large-scale prospective studies are needed to analyze the prevalence of ASD and PTSD, the rate of progression from ASD to PTSD, and the type of pattern identification.

• Journal of Korea Entertainment Industry Association
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• v.15 no.1
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• pp.63-73
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• 2021

This study aims to analyze music of Yoon-sang, as a part of musical research, which is the most fundamental approach among academic studies on Korean popular music. Yoon-Sang is a representative composer, who has gone through the 1980s to the present. The result of analysis of 21 songs created by Yoon-Sang showed that his songs are mostly characterized by tonal music, in which chord relationships develop focusing on keynotes. The reason why his music does not sound uniform pursuing stability is he properly added the progression of chromatic chords, based on diatonic chords and melodies. Dominant 7th chord and diminished 7th chord are used the most among diverse techniques adding chromatic colors. Along with these chords, chromatic intervals are used not only in chord progression but also in melodies. The successive, ascending or descending movement of the base line is his common composition and arrangement technique revealed in every song. One of formal changes with the stream of the times is that the number of measured in the pre-chorus and interlude that were of great importance in his songs of the 1990s decreased over time. With regard to harmonic changes, whereas modulation between parts was applied to his 2 songs created in the 2010s. Yoon-Sang's music had one strong tonality overall, but his music began to have more than two tonalities starting the 2010s, and this is a big variation in his music.

• Journal of Bio-Environment Control
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• v.31 no.2
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• pp.125-132
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• 2022

This study aimed to examine cucumber (Cucumis sativus) varieties adaptive to the desert climate by comparing and analyzing the growth, yield, and water consumption. Two long-sized cucumber varieties, 'Gulfstream' and 'Imea' and two medium-sized cucumbers, 'Nagene' and 'Sausan' were cultivated in coir substrate hydroponics under hot and humid greenhouse conditions from March 2 to June 20, 2020. On the 113 DAT, 'Nagene' had the longest plant height and the highest internode number. The marketable fruit number per plant was higher in the medium-sized varieties, which had more internode number. The marketable fruit number was 31.3 for 'Gulfstream', 30.7 for 'Imea', 57.8 for 'Nagene', or 56.0 for 'Sausan' with no significant difference in total fruit weights per plant. The water consumption required to produce 200 g of fruit was lower in the 'Nagene' (2.39 L) with the highest water use efficiency (WUE). Therefore, 'Nagene' variety may have higher adaptability to desert high temperature compared to the long-sized varieties, and it is going to be necessary to verify more medium-sized cucumber varieties.

• Journal of Bio-Environment Control
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• v.31 no.3
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• pp.212-220
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• 2022

When it comes to single node leafy stem cuttings of rose (Rosa hybrida), environmental management such as air temperature, relative humidity, and light affect productivity. In order to investigate the effect of air temperature and relative humidity on the cutting success rate and rooted cuttings quality, a transparent airtight box was used to implement a closed system. We have also tried to find out the most effective photoperiod and the number of leaflets in closed system using artificial light (white LED, 104.0 µmol·m^-2·s^-1 photosynthetic photon flux density). The first experiment was conducted for a total of 6 weeks under 4 airtight period conditions. The number of roots and longest root length decreased as the airtight period increased. But there were no significant differences in the survival rate, shooting rate, and rooting rate according to airtight periods. In the second experiment the results indicated that survival and shooting rate were significantly affected by the photoperiod (0/24, 2/22, 4/20, 8/16, and 16/8 h), the number of leaflets (0, 2, and 4 leaflets) of the cuttings and their interaction. The survival rate was the highest in the 16-h day length and 4 leaflets. By considering survival rate and shooting rate with energy efficiency, the 8-h day length and 2 or 4 leaflets were judged to be the most effective.

• Journal of Bio-Environment Control
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• v.32 no.1
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• pp.34-39
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• 2023

Growth modeling in plant factories can not only control stable production and yield, but also control environmental conditions by considering the relationship between environmental factors and plant growth rate. In this study, using the expolinear function, we modeled perilla [Perilla frutescens (L.) Britt.] cultivated in a plant factory. Perilla growth was investigated 12 times until flower bud differentiation occurred after planting under light intensity, photoperiod, and the ratio of mixed light conditions of 130 μmol·m^-2·s^-1, 12/12 h, red:green:blue (7:1:2), respectively. Additionally, modeling was performed to predict dry and fresh weights using the expolinear function. Fresh and dry weights were strongly positively correlated (r = 0.996). Except for dry weight, fresh weight showed a high positive correlation with leaf area, followed by plant height, number of leaves, number of nodes, leaf length, and leaf width. When the number of days after transplanting, leaf area, and plant height were used as independent variables for growth prediction, leaf area was found to be an appropriate independent variable for growth prediction. However, additional destructive or non-destructive methods for predicting growth should be considered. In this study, we created a growth model formula to predict perilla growth in plant factories.

• Journal of Life Science
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• v.33 no.2
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• pp.176-182
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• 2023

The stems of Dendrobium moniliforme are used in traditional Oriental medicine as a Yin tonic to nourish the stomach, promote the production of body fluid, and reduce fever. This study investigated the effects of the aqueous extract of D. moniliforme stems (DME) on mast cell degranulation and the expression of tumor necrosis factor-α (TNF-α), interleukin-4 (IL-4), and histamine-synthesizing enzyme histidine decarboxylase (HDC). We used rat mast cell line RBL-2H3 cells and stimulated them with PMA plus calcium ionophore (PMACI). Pretreatment with DME significantly inhibited PMACI-induced β-hexosaminidase release and the expression of TNF-α, IL-4, and HDC. Furthermore, DME suppressed PMACI-induced nuclear translocation of the nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) and activator protein 1 (AP-1). In addition, HDC expression was inhibited by SP600125 (JNK inhibitor), PD98059 (ERK inhibitor), and SB203580 (p38 kinase inhibitor). Finally, the phosphorylation of p38 kinase, extracellular signal-regulated kinase 1/2 (ERK1/2), and c-Jun N-terminal kinase (JNK) was inhibited by pretreatment with DME. These results suggest that DME has inhibitory effects against degranulation, cytokine (TNF-α and IL-4) and HDC expression, and that HDC expression is mediated by MAPK signaling. These findings suggest that DME may have therapeutic potential in the treatment of hypersensitive and inflammatory diseases.