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Adolescent obesity and the elevation of aminotransferase levels (청소년 비만과 혈청 아미노 전이 효소 증가)

  • Kim, Su Yeon;Lee, Ho Jun;Park, Tae Su;Kim, Soo Geun;Shin, Hye Jung
    • Clinical and Experimental Pediatrics
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    • v.49 no.10
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    • pp.1037-1041
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    • 2006
  • Purpose : The prevalence of obesity and nonalcoholic steatohepatitis(NASH) was increased in adolescents. This study was performed to observe the prevalence of elevated aminotransferase levels in adolescents and to assess the correlations between aminotransferase levels and obesity related parameters(body mass index, waist circumference, hip circumference, waist to hip ratio and insulin level). Methods : We obtained weight, height, waist circumference and hip circumference from 2,417 male and 1,219 female adolescents. Mean age was $15.7{\pm}0.7$ years old. We measured fasting insulin, aspartate aminotransferase(AST) and alanine aminotransferase(ALT). Obese and overweight were defined as body mass indices(BMI) of more than the 95th, and 85th-94th percentiles, respectively, for age and sex. Results : The number of adolescents with obesity is 324(8.9 percent). 414(11.4 percent) subjects belonged to the overweight group. The average ALT level of obese, overweight and control groups were significantly different(obese : $32.1{\pm}34.3U/L$, overweight : $19.6{\pm}13.6U/L$, control : $12.7{\pm}6.7U/L$, P<0.001). The average AST level was also different according to group(obese : $27.8{\pm}16.5U/L$, overweight : $22.8{\pm}8.6U/L$, control : $20.8{\pm}8.5U/L$, P<0.001). AST and ALT were correlated with anthropometric parameters and insulin level. After multiple regression analysis, waist circumference was the significant predictive value for AST(r=0.234, P<0.001). Waist circumference, BMI and insulin levels were significant predictive values for ALT(r=0.435, P<0.001). Conclusion : The prevalence of abnormal aminotransferase was higher in the obese and overweight groups than control group. Waist circumference was useful to predict abnormal aminotransferase levels.

Relationship between Body Fat Distribution and Metabolic Risk Factors in Adolescents (청소년에서의 체지방 분포와 대사위험 인자들의 연관성)

  • Kim, Dal Hyun;Seong, Tae Jung;Hong, Young Jin;Son, Byong Kwan;Kim, Soon Ki
    • Clinical and Experimental Pediatrics
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    • v.46 no.4
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    • pp.326-334
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    • 2003
  • Purpose : The objectives of this study were to estimate the prevalence of obesity in adolescents; to study the association between obesity, blood pressure, and dyslipidemia; and to evaluate the superiority of waist circumference to waist/hip ratio(WHR) in central obesity. Methods : We selected 1382 adolescents(M : F=690 : 692) aged from 11 to 18 years(mean age; boys 15.0, girls 15.4) in Incheon. We measured weight, height, waist, waist/hip ratio, and blood pressure, with blood sampling to evaluate the dyslipidemia. Results : The prevalence of obesity was 6.7% in boys and 6.9% in girls by body mass index(BMI). The prevalence of systolic hypertension was 15.7% in normal group, 32.4% in the overweight group, and 35.4% in the obese group by BMI. The prevalence of diastolic hypertension was 4.9% in the normal group, 6.9% in the overweight group, and 14.6% the in obese group. In boys and girls, BMI, waist circumference, and WHR were positively correlated with systolic and diastolic blood pressure. respectively. In boys, triglyceride was positively correlated with waist circumference(r=0.34, P<0.05). In boys and girls, BMI was highly correlated with obesity index(r=0.98, each), with waist circumference(r=0.89, r=0.82, respectively), and with body fat(r=0.85, r=0.89) respectively. Conclusion : These data suggest the importance of the screening of blood pressure in obese adolescents, with prevention and intervention of obesity since it may be the most cost-effective way of reducing the complications related with obesity.

Childhood Obesity and Cardiovascular Health: Using 2010-2012 Data of the Korea National Health and Nutrition Examination Survey (아동기 인구 집단의 비만과 심혈관건강: 제5기 국민건강영양조사 자료 이용)

  • Lee, Go Eun;Choo, Jina
    • Korean journal of health promotion
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    • v.17 no.2
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    • pp.109-118
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    • 2017
  • Background: Abdominal obesity as measured by waist-to-height ratio (WHtR) may have stronger and inverse associations with cardiovascular (CV) health than overall obesity as measured by body mass index (BMI). However, there was some challenges for controversies. We aimed to examine the associations of WHtR and BMI with CV health among Korean children using data of the 2010-2012 Korea National Health and Nutrition Examination Survey. Methods: A cross-sectional study was conducted with the sample of 2,363 children by analyzing by gender and two-age groups (10-12 and 13-18 years). Overall obesity was categorized into 3 groups by BMI percentile: non-overweight (<85), overweight (${\geq}85$), and obesity groups (${\geq}95$). Abdominal obesity was categorized into 2 groups by WHtR: normal (<0.5) and abdominal obesity groups (${\geq}0.5$). The CV health score was defined as a z-score by calculating the sum of 7 CV factors. Results: The overweight/obesity groups had significantly lower CV health scores than the normal group (P<0.05) in boys and girls aged either 10-12 years or 13-18 years after adjusting for covariates. The abdominal obesity group also showed significantly lower CV health scores than the normal group (P<0.05) in all the groups; this significant association remained significant in boys aged 13-18 years even after further adjusting for BMI category (P<0.01). Conclusions: Among boys aged 13-18 years, abdominal obesity as measured by WHtR was significantly and inversely associated with CV health, independent of BMI category. Therefore, it should be considered to assess the level of abdominal obesity as a measure of CV health in late adolescent boys.

Ablation Characteristics of Bovine Liver According to Cool-Tip Temperature of RFA Equipment (고주파 열치료 장비의 Cool-Tip 온도에 따른 소간의 소작 특성)

  • Choi, Young-Jae;Kim, Jeong-Koo
    • Journal of radiological science and technology
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    • v.38 no.2
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    • pp.155-161
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    • 2015
  • This study confirmed the correlation between the change of the cooling water in internal cooling system and the size of the ablation site of bovine liver in RF heat treatment equipment. The bovine liver was resection with $4{\times}4{\times}4cm^3$ in 2cm cool-tip and with $6{\times}6{\times}6cm^3$ in 3cm cool-tip for the experiments. Area and perimeter of the ablation site for bovine liver were measured by Freehand techniques of MRI. It showed area and perimeter decreased during cool-tip temperature rises 6 and 12 minutes ablation using a 2cm and 3cm cool-tip. The correlation of cool-tip temperature and area and perimeter was statistically significant the result are shown(p=.000). The measurements of area and perimeter were more accurate with MRI in actual measurements and MRI for ablation range. The statistical results using Paired sample T-test was also significant(p=.038). The ablation range of bovine liver decreased according as cooling water temperature increases in RF heat treatment equipment for reason of carbonization occurred due to does not accurately pass the RF energy. Therefore, it is considered the effect of RF heat treatment would be increased if the temperature of the cooling water consistently maintain the low temperature in order to reduce the generation of carbide at RF heat treatment and RF energy is delivered accurately.

The Relationship between Factors of Metabolic Syndrome in Korean Adult Males and the Parents' Family History of Diabetes (한국 성인 남자의 대사증후군 인자와 부모의 당뇨병 가족력 관계)

  • Park, Hyung-Su;Jeong, Jin-Gyu;Yu, Jin-Ho
    • The Journal of the Korea institute of electronic communication sciences
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    • v.8 no.5
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    • pp.779-784
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    • 2013
  • This study aims to look into the relationship between the parents's family history of diabetes and factors of metabolic syndrome focusing on Korean adult males with a family history of diabetes. The data used for the study was collected from the 2010 Korea National Health and Nutrition Examination Survey. The subjects of the study totaled 2,045. For statistical analysis, double sampling general linear regression was used and the statistical significance was p<0.05. As a result of a multi-variate analysis with general characteristics corrected, the following was discovered: when fathers had a family history of diabetes, girth increased by 2.5cm, fasting blood sugar(glu) increased by 9.6mg/dL and neutral fat increased by 41.6mg/dL When the mothers had a family history of diabetes, girth increased by 2.4cm, fasting blood sugar(glu) increased by 15.4mg/dL, and the neutral fat increased by 27.2mg/dL. In conclusion, when the fathers had a family history of diabetes, their children's girth, fasting blood sugar and neutral fat were significantly higher, and when the mothers had a family history of diabetes, their children's girth and fasting blood sugar were significantly higher.

The Effect of Community-based Health Intervention Program to Improve Metabolic Disease in Jeju Island (제주 지역주민기반 대사성질환 개선 프로그램 중재 효과)

  • Kim, Woo Jin;Kim, Sang Hoon;Park, Shin Young
    • Korean Journal of Clinical Laboratory Science
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    • v.50 no.3
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    • pp.297-303
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    • 2018
  • This study investigated the effect of community-based health intervention program to improve metabolic disease in Jeju island. There were 50 obese local residents in the experimental group (body mass index, $BMI{\geq}25kg/m^2$). They participated in cooking therapy with nutrition education (4 times), exercise program with proprioceptive neuromuscular facilitation (PNF) and stretching training (9 times), and alternative medicine program with healing touch massage (3 times) during a 3-week period. To evaluate the effectiveness of the program, body composition, blood lipid profiles, blood glucose, and waist circumference were assessed before and after the intervention program. After the program, the value of total cholesterol (TC), glycosylated hemoglobin (HbA1C), diastolic blood pressure, percent body fat, and waist circumference were decreased, and became the normal value. Especially, HbA1C, percent body fat, and waist circumference were significantly decreased (P<0.001) in the experimental group, while HbA1C, percent body fat, and waist circumference were significantly increased (P<0.001) in the control group (N=50), who had no intervention. Our results suggest that metabolic syndrome associated markers need intervention program for improving them. In conclusion, although this study did not analyze the effect of the health intervention program and cooking therapy separately, considering the result of this 3-week, short term program, the effect will be more profuse if cooking therapy and exercise program were performed concurrently.

General and abdominal obesity and risk of cardiometabolic factors in the community dwelling women (순환대사위험요인의 관련성에서 비만지표인자인 허리둘레와 체질량지수의 비교)

  • Shin, Sohee;So, Wi-Young;Kim, Hyun Soo
    • Journal of the Korea Convergence Society
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    • v.9 no.1
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    • pp.233-240
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    • 2018
  • The aim of this study was to investigate the cardiometabolic risk factors (CRF) of community dwelling women based on a combination of body mass index (BMI) and waist circumference (WC). This cross-sectional study was based on 1,447 subjects between 30 and 60 years of age. Subjects were categorized into 4 groups by BMI and WC [group 1, BMI<$25kg/m^2$ and WC<85 cm; group 2, BMI<$25kg/m^2$ and WC>85 cm; group 3, BMI>$25kg/m^2$ and WC<85 cm; and group 4 (BMI>$25kg/m^2$ and WC>85 cm. Logistic regression analyses showed that subjects in group 2 had 1.75 times increased risk of clustering of 2 or more CRFs compared with subjects in group 1 (p<0.001). In conclusion, early detection of people with normal weight but high waist circumference may prevent them from getting worse by implementation of lifestyle intervention, consisting of regular exercise and healthy eating. In addition, further studies on appropriate exercise contents for them should be examined.

A Study on Visitors' Characteristics and Cognition in Regard to Damage of Nature Environment in Different Types of Ecotourism Destination (생태관광지 유형별 탐방객 특성 및 자연환경 훼손에 대한 인식 비교 연구)

  • Lee, Ho-Young;Oh, Choong-Hyeon
    • Korean Journal of Environment and Ecology
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    • v.26 no.2
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    • pp.264-272
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    • 2012
  • For understanding the tourists' characteristics of several types of ecotourism sites, we surveyed and analyzed the demographic characteristics, travel motivations and cognition of damage in Bukhansan trail, Upo marshes, Jirisan trail and Uljin Keumgang pine tree trail. The field survey were conducted through face-to-face interviews. In the case of Bukhansan trail, many people came to build up their health, so the ratio of eco-tourists and the awareness of environmental damage was low. In Upo marshes, there were many group tourists who want to enhance friendship between the colleagues. And the ratio of eco-tourists, enjoying several activities such as observation or experience about the ecosystems of wetland and bird watching appeared high, but the cognition of tourists about the damage of natural environment was low because the flatland type tour site, Upo marshes has less damage factors comparing with mountain type tour sites. In Jirisan trail, eco-tourists, nature tourists and mass tourists appeared mixed and the cognition of damage was higher than that of flatland type. In the case of Uljin Keumgang pine tree trail, almost indices showed higher values than other sites because the tourists who visited there have high cognition of eco-tourism and nature conservation by limiting entrance. Tourists were generally accepted positively the control method such as collection of entrance fee and visitor reservation system when natural damages are expected.

Effect of Improve Obesity with Sprout Raw Grains and Vegetables (발아 생식을 이용한 비만개선 효과에 관한 연구)

  • 서정숙;방병호;여인법
    • The Korean Journal of Food And Nutrition
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    • v.14 no.2
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    • pp.150-160
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    • 2001
  • This study was carried out to investigate the effect of weight loss and the change of serum lipids composition for normal and obese women after sprout raw grains and vegetables diet intake. Diet were given to the subjects which were composed of 11 normal women and 7 obese women for 4 weeks. After diet intake, 4.6% in normal group and 3.5% in obese group were shown weight loss. And the both groups of normal and obese women showed a significant reduction in the thickness of subcutaneous fat and the body girth. Particularly, the waist measure was shown to be remarkably reduced in the normal group (p< 0.0001) and to be reduced in the obese group (p<0.017) significantly. After diet intake. the levels of total cholesterol and triglycerides were reduced in both groups significantly. And in the obese women, HDL-cholesterol level increased 5.7%. As those results, it could be seen that weight and the thickness of subcutaneous fat were reduced and the component of blood serum were improved after diet intake for 4 weeks. Specially, abdomen, waist measures and hip girth were reduced remarkably, so it is considered that the diet is more effective in the diet therapy of obese women with upper obese status.

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The Relationship between Serum Leptin Concentration and Obesity Indices in a Rural Population (일부 농촌지역 주민의 혈청 leptin 농도와 비만지표의 관련성)

  • Shin, Min-Ho;Park, Kyeong-Soo;Choi, Jin-Su;Kim, Sang-Yong
    • Journal of Preventive Medicine and Public Health
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    • v.33 no.2
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    • pp.193-198
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    • 2000
  • Objective : To evaluate the relationship between serum leptin concentration and obesity indices in a rural population. Methods : Two hundred and nine subjects were randomly sampled from 1036 residents who had participated in the survey. Their obesity indices were measured by bioelectrical impedance analysis and anthropometry. Serum leptin concentrations were measured by immunoradiometric assay. Results : Serum leptin concentrations were positively correlated with body mass index, percent of body fat, fat mass, waist circumference, and hip circumference. Serum leptin concentrations were higher in obese or overweighted subjects than normal or thin subjects(8.5[0.9-31.4] compared with $2.7[0.1-12.0]{\mu}g/L$, p<0.01). Serum leptin concentrations were higher in women than men, even after an adjustment to body mass index$(\beta=4.183,\;p<0.01)$. According to body composition, serum leptin concentrations were more related with waist circumference in men, hip circumference in women. Conclusions : Serum leptin concentrations are positively correlated with obesity indices. Serum leptin concentrations are higher in obese subjects, in women, and more related with peripheral obesity. These findings support the hypothesis that human obesity is associated with leptin-resistance rather than leptin-deficiency.

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