• Proceedings of the Korea Information Processing Society Conference
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• 2014.11a
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• pp.323-326
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• 2014

IT 기술의 발전으로 'U-Health'를 기반으로 하는 건강관리 앱의 필요성이 증가하고 있다. 'U-Health'는 무선 인터넷 기술을 이용하여 질병의 예방과 치료를 위한 원격진료 서비스로서 다양한 형태로 사용자들에게 제공된다. 본 논문에서는 안드로이드 플랫폼을 활용하여 근골격계 환자가 의사의 도움 없이 스마트기기를 이용하여 텍스트 문진과 이미지 문진을 통해 의사의 진단과 동일한 결과를 얻을 수 있는 건강관리 앱을 소개한다. 그리고 예약 및 진료 정보 등 병원에서 제공하는 서비스를 스마트기기 상에서 이용할 수 있도록 병원 시스템과 연동하였다.

• Proceedings of the Korea Information Processing Society Conference
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• 2014.11a
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• pp.57-58
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• 2014

본 연구에서는 여러 가지 생체 신호 중 심전도 신호를 대상으로 하여 개인별 구분이 가능한 특이점이 검출 되는지 기계 학습을 통하여 검증하였다. 심장 질환이 없는 정상인을 대상으로 수집한 신호로 부터 8가지 기점 특징을 추출하였으며, 동일 오류율과 AUC를 평가 척도로 하여 SVM 분류기를 이용한 경우 개인별 특이점이 효과적으로 구분됨을 확인하였다.

• Proceedings of the Korean Information Science Society Conference
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• 2010.06c
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• pp.230-234
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• 2010

심전도는 가장 일반화되어 있는 생체신호의 하나이다. 심전도를 측정하여 심장병의 유무와 여러 질환들을 예측하고 예방할 수 있다. 심전도 신호를 추출 하는 방법에는 여러 방법이 있는데, 본 논문에서 활용한 두 논문은 계층적인 분류로 HOS, HBF, HMH 세 방법으로 실험을 하였고, 적응가변형 윈도우를 이용한 R파 추출을 실행하였다. 두 논문은 공통적으로 MIT-BIH Arrhythmias Database(MIT-BIT 부정맥 데이터베이스)를 데이터로 실험 하였으며, 알고리즘으로는 SVM, Cross-Validation등을 사용하였다. 마지막으로 두 논문의 실험결과를 바탕으로 정확도를 높일 수 있는 효과적인 알고리즘 연구를 제안하였다.

• The Journal of Korean Obstetrics and Gynecology
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• v.32 no.1
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• pp.15-25
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• 2019

Objectives: The aim of this study is to review clinical studies of Hominis Placenta Pharmacopuncutre on Obstetrics & Gynecology diseases. Methods: Key words "Jahageo Yakchim", "Hominis Placenta Pharmacopuncture", "Human Placenta Pharmacopuncture", "Hominis Placenta Pharmacoacupuncutre" were searched on 6 database systems (DBpia, KISS, KTKP, NDSL, Pubmed, CENTRAL) on August 31th 2018. Results: 1 case reports and 4 controlled studies were collected in accordance with the selection and exclusion criteria. The study design, study results and method of intervention were analyzed. Conclusions: This review shows the necessity of large-scale well designed clinical studies of Hominis Placenta Pharmacopuncture on Obstetrics & Gynecology diseases to evaluate the efficacy and safety.

• Proceedings of the Korea Information Processing Society Conference
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• 2021.11a
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• pp.397-399
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• 2021

한의사의 복진을 모사하는 진단기기와 이를 이용하여 질환과 변증을 분류하는 알고리즘을 개발하는 연구가 진행되고 있다. 본 연구에서 적외선 체열 영상과 접촉식 온도계로부터 구성되는 복부 영역별 체열 영상 시스템을 제시하였고, 복부 영역의 절대 온도를 보정하는 방법을 살펴보았다. 접촉식 온도계를 활용해 추가로 복부표면 온도를 측정하였고, 동시에 열화상 카메라로도 영상을 촬영하여, 동일위치에서 열화상 영상의 온도값과 접촉식 체온계의 온도값을 비교해 전체 열화상 영상을 보정하였다. ICC 값이 0.96으로 나와 높은 재현성을 보였다.

• Clinical and Experimental Pediatrics
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• v.51 no.6
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• pp.640-645
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• 2008

Purpose : It is widely known that allergic diseases progress through an allergic march. However, there have not been any recent reports in Korea on how the diseases progress. Methods : Parents who visited one of the Pediatric Allergy Clinics of four university hospitals in Seoul with a child under the age of 6 years during the period from May 1-30, 2006 were asked to complete a questionnaire. Results : A total of 229 parents answered the questionnaire about their children, of which 122 were male and 107 were female. The most common allergic disease before 2 years of age was atopic dermatitis (79%). Meanwhile, in 2- to 4-year age group, allergic rhinitis (38%) and asthma (37%) were predominant. The most common allergic disease in the 4- to 6-year age group was asthma (72%), followed by allergic rhinitis (64%). Seventy-three percent of the children had a family history of allergic disease, most often in the fathers (39%). Among patients with allergic rhinitis, 50% had experienced asthma in their earlier days and 30% had experienced atopic dermatitis. In addition, 57% of the children with asthma had suffered from atopic dermatitis. Parents believed that asthma was the most serious allergic disease. Conclusion : In the present study, allergic disease showed a tendency to march from atopic dermatitis to asthma and then to allergic rhinitis. Early diagnosis and treatment of atopic dermatitis is, therefore, considered important for prevention of the allergic march.

• Childhood Kidney Diseases
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• v.15 no.1
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• pp.49-57
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• 2011

Purpose: The aim of this study is to investigate the change in incidence and clinical characteristics of acute poststreptococcal glomerulonephritis (APSGN) through a single center's experience. Methods: We retrospectively analyzed the medical records of 53 children who were diagnosed with glomerular nephritis at National Health Insurance Corporation Ilsan Hospital between March 2000 and December 2009. Twenty-six of 53 patients falled to meet the dragnostic criteria of APSGN and were excluded. Chief complaints, physical examinations, urinalysis, urine culture, laboratory results, chest x-ray, and clinical manifestations were all retrieved from the remaining 27 patients. Results: The incidence of APSGN by age was highest in children between six to seven years of age, with similar distributions in both genders, and seasonal incidence was higher from November to February when compared to other months, which was similar to the previously reported studies. However, the annual number of APSGN patients did not show a significant decrease from 2000 to 2009. The incidences of edema and hypertension were 59.3% and 48.1% respectively, suggesting lower incidences than those from previous studies. Six patients (22.2%) experienced hematuria for more than 6 months. Hypertensive encephalopathy, one of APSGN critical complications occurred in one patient but resolved with conservative treatment. Conclusion: Our study shows that APSGN still occur as a common renal disease but the disease severity seems to decrease with milder clinical manifestations and less complications compared to past studies.

• Journal of Genetic Medicine
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• v.5 no.2
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• pp.111-118
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• 2008

Purpose: Neonatal screening tests are increasingly being used forearly diagnosis of inborn errors of metabolism (IEM) in the hope of avoiding the severe developmental delay, acute illness, and death that may result from these diseases. In this study, a cost-benefit analysis was performed on the neonatal screening of maple syrup urine disease, homocystinuria, galactosemia, and congenital adrenal hyperplasia in Korea. Materials and Methods: This study included 1,259,220 Korean newborns born between January 2005 to December 2007, who were screened for maple syrup urine disease, homocystinuria, galactosemia, and congenital adrenal hyperplasia. We calculated and compared the total costs in cases where these four screening tests were implemented, and those where they were not. Results: There were no benefits to screening for maple syrup urine disease or homocystinuria due to their low prevalence for these two tests, the costs exceeded the benefits at benefit:cost ratios of 0.5:1 and 0.6:1, respectively. In contrast, benefits far exceed costs at a ratio of 4.1:1 for galactosemia and 2.9:1 for congenital adrenal hyperplasia. The average benefit:cost ratio for all four tests was 2.0:1. Conclusion: Neonatal screening tests for maple syrup urine disease, homocystinuria, galactosemia, and congenital adrenal hyperplasia are financially viable.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.4 no.1
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• pp.54-62
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• 2001

Purpose: There have been few reports about common gastrointestinal diseases in children visiting emergency room. The aim of this study was to present basic data and their meanings about emergency room utilization in children with nonsurgical gastrointestinal disorders. Methods: The authors prospectively studied 1,228 consecutive children with gastrointestinal diseases, amongst 6,179 nonsurgical pediatric patients who visited the emergency room of Seoul Red Cross Hospital from Jan. 1st 1998 to Dec. 31st 1999. Results: 1) First visit was 60.7% of total visits and 30.7% were between 1 and 3 years of age while 80.4% were below 6 years of age. Male patients were predominant by a ratio of 1.3:1. 2) The peak month of visits was December (12.1%), and the peak time of visits was between 8:00 pm and midnight (35.9%). Average length of stay at emergency room of the total patients were 0.86 hour. 3) Five major diseases were acute gastroenteritis (44.3%), fecal impaction &/or constipation (21.3%), acute gastritis (16.4%), intussusception (4.6%), and infantile colic (4.3%) in order. 4) 19.6% of the total patients were hospitalized. Conclusion: There were differences in various distributions regarding each nonsurgical gastrointestinal disease entity in children visiting emergency room even though distributions of the total patients in our study were not so different from those in previous reports by others.

• Clinical and Experimental Pediatrics
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• v.46 no.5
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• pp.467-473
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• 2003

Purpose : The Epstein-Barr virus(EBV), gamma herpesvirus, is an important pathogen that is widespread around the world. The EBV causes various diseases depending on the geographic location, and on the immunity or the premorbid condition of the person exposed to EBV. To evaluate EBV typing may be the most important step to figure out the pathogenesis of EBV associated diseases, and we need to re-evaluate the pathologic role of human leukocyte antigen(HLA) in developing Epstein- Barr virus associated acute infectious mononucleosis by using newly developed methods. Methods : This study included 24 children(age range : 6 to 13 years), serologically confirmed with acute infectious mononucleosis. The control group for the HLA type consisted of 200 age-matched healthy children. To classify HLA I, modified ARMs-PCR was used, while modified PCR-SSOP was utilized in typing of HLA II. Also, we performed EBV typing in study patients by using a one-step PCR. Results : The results of HLA types : In HLA class I, HLA-A24 was positive in 69 of 200 healthy children and positive in 14 of 24 patients in the study group(relative risk : 3.5724, chi-square; 5.26, P<0.05). In HLA class II, HLA-DRB1*07 was detected in 18 of 200 healthy children, and eight of 24 patients in the study group(relative risk; 506173, chi-square; 9.73, P<0.01). The results of EBV types : In the research group, 20(83.8%) of 24 patients were shedding type A virus, while 4(16.7%) were type B. Conclusion : We conclude that development of infectious mononucleosis may be associated with HLA types, and these results suggest that acute infectious mononucleosis could have hereditary traits. And we confirm that type A EBV is highly prevalent in patients with acute infectious mononucleosis in Korea. Also, our results suggest that further large scale studies, including adult groups, regarding the association between pathogenesis of EBV with HLA-DP or HLA-DQ will be warranted.