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Effects of Non-Invasive Constant Microcurrent Stimulation on Expression of BMP-4 After Tibia Fracture in Rabbits (비침습식 미세전류자극이 토끼 경골의 골절 후 BMP-4 발현에 미치는 영향)

  • Cho, mi-suk
    • Proceedings of the Korea Contents Association Conference
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    • 2009.05a
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    • pp.1124-1129
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    • 2009
  • This study aims to examine the effects of non-invasive constant microcurrent stimulation on expression of Bone Morphogenetic Protein(BMP) 4 after tibia fracture in rabbits. Twenty four rabbits with tibia fracture were randomly divided into control and experimental groups. Each group was divided into four subgroups, based on the duration of the experiment (3, 7, 14, 28 days). The experimental groups received a constant microcurrent stimulation of $20{\sim}25{\mu}A$ intensity with surface Ag-AgCl electrode (diameter 1cm, Biopac, U.S.A.) for 24 hours a day. Cathode of the microcurrent stimulator located on the tibia directly, anode of it did on the gastrocnemius muscle. Rabbits were sacrificed on each of the postoperative days 3, 7, 14, 28. To investigate how non- invasive constant microcurrent stimulation affects bone healing, immunohistochemical analysis of BMP-4 was performed at each point. After evaluation, the test results are as follows: Comparisons of immunohistochemical observation of BMP-4 in 7 days after tibial fracture show that there was shown to be a moderate positive reaction (++) on concentric circles of Harversian system andt he interstitial lamella in the control group, while there was a very strong positive reaction (++++) on concentric circles of Harversian system and interstitial lamellain the experimental group. These results suggest that applying non-invasive constant microcurrent stimulation on fractured bone is helpful to bone healing.

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Study on Heat Transfer Characteristics of Internal Heat Exchanger for $CO_2$ Heat Pump under Heating Operating Condition (난방운전 조건하에서 $CO_2$ 열펌프용 내부 열교환기의 열전달 특성에 대한 연구)

  • Kim, Dae-Hoon;Lee, Sang-Jae;Choi, Jun-Young;Lee, Jae-Heon;Kwon, Young-Chul
    • Journal of Energy Engineering
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    • v.17 no.2
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    • pp.116-123
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    • 2008
  • In order to study the heat transfer, effectiveness and pressure drop of an internal heat exchanger (IHX) for $CO_2$, heat pump under heating condition, the experiment and numerical analysis were performed. Four kinds of IHXs were used. The section-by-section method and Hardy-Cross method were used for the numerical analysis. The effects of IHX on the flow rate of refrigerant, the IHX length, the operating condition of a gas-cooler and an evaporator and the type of IHXs were investigated. With increasing the flow rate, the heat transfer rate increased about 25%. The heat transfer of the micro-channel tube was larger about 100% than that of the coaxial tube. With increasing the IHX length, the heat transfer rate decreased. The low-side pressure drop was larger compared with that of the high-side. And the pressure drop of the microchannel tube was larger about 100% than that of the coaxial tube. With increasing the high-side temperature and decreasing the low-side temperature, the heat transfer rate increased about 3%. From this study, we can see that new correlation on $CO_2$ heat transfer characteristics and tube type is necessary.

A Practical Algorithm to Simulate Erosion of On-Shore Zone (실용적 해안선 후퇴 반영 알고리즘)

  • Kim, Hyoseob;Lee, Jungsu;Jin, Jae-Youll;Jang, Changhwan
    • Journal of Wetlands Research
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    • v.15 no.3
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    • pp.423-430
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    • 2013
  • An algorithm to allow shoreline movement during numerical experiment on sediment transport, deposition or resuspension for general coastal morphology is proposed here. The bed slope near shoreline, i.e. mean sea level, is influenced by bed material, tidal current, waves, and wave-induced current, but has been reported to remain within a stable range. Its annual variation is not large, either. The algorithm is adjusting the bathymetry, if the largest bed slope within shoreline band exceeds a given bed slope due to continuous erosion at zones below the shoreline. This algorithm automatically describes retreat of shoreline caused by erosion, when used within a numerical system. The algorithm was tested to a situation which includes a continuous dredging at a point, and showed satisfactory development of concentric circle contours. Next, the algorithm was tested to another situation which includes sinking of eroded part of bed plate, and produced satisfactory results, too. Finally, the algorithm was tested to a movable-bed laboratory experimental conditions. The shoreline movement behind detached breakwater was reasonably reproduced with this algorithm.

Study on the Production Methods and Conservation Treatment of the Gold Earrings Excavated from the Ancient Tombs in Seokchon-dong in Seoul (석촌동 고분군 출토 금제이식의 제작기법 연구 및 보존처리)

  • Kim, Yeseung;Jeong, Seri;Lee, Dahye;Jang, Minkyeong;Kim, Naeun;Yang, Seokjin
    • Conservation Science in Museum
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    • v.26
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    • pp.143-160
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    • 2021
  • The Seoul Baekje Museum has been conducting excavations at the Ancient Tomb Complex in Seokchon-dong, Seoul (Historic Site No. 243), known to be tombs of the royal family and the ruling class during the Hanseong period of the Baekje Kingdom. In this study, gold earrings that were revealed during the excavation underwent scientific analysis and conservation treatment. Stereo microscopy, SEM, X-ray imaging, CT, and XRF were applied in the analysis, and the characteristics, internal structure, and composition of the earrings as well as their production method were investigated. The results confirmed that the main hoops of the gilt-bronze earrings were made of copper cores gilt using mercury amalgamation. The findings also revealed that the hexahedron in the middle pendant was made by connecting small rings using molten gold powder, and the pendant sphere at the end was formed by soldering two hemispheres. As for the two thin-hoop earrings, they showed similar surface compositions but were made using different methods, with one made from a copper core wrapped with a gold plate and the other made by bending a gold rod. The gold content varied depending on the item and the place of measurement, but overall the earrings showed a relatively high gold content of approximately 19 to 21K. The purity of the golden earrings and the sophisticated manufacturing techniques applied indicate the high status of the buried person and of the tomb complex in Seokchong-dong.

An Application of Electrical Resistance Method for Monitoring of Rotating Cylindrical Separator (원통형 회전 분리기를 감시하기 위한 전기저항법의 이용)

  • Lee, Bo-An;Kim, Sin
    • Journal of Energy Engineering
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    • v.20 no.1
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    • pp.21-25
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    • 2011
  • In order to monitor a rotating cylindrical separator for radioactive waste, an electrical resistance method is proposed and its mathematical model is investigated. In a rotating radioactive waste separator, the electrical resistance between a pair of electrodes mounted on the inner wall of the vessel is related to the thickness of annular region of insoluble particle formed around the periphery and the concentration of the insoluble particle in that region. This work presents an analytical relationship among the aforementioned parameters based on a two-dimensional solution to the electrical potential equation and an empirical conductivity-concentration relation. Also, the feasibility of electrical resistance method for monitoring rotating cylindrical separators is discussed.

A Study on the Flow Field Analysis with a High-frequency Ultrasonic by PIV Measurement (PIV 계측에 의한 고주파수 초음파 유동장 해석에 관한 연구)

  • Lee, Sang-Bum;Song, Min-Geun;Son, Seung-Woo;Jeong, Gwang-Su;Ju, Eun-Sun
    • Proceedings of the KSME Conference
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    • 2001.06e
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    • pp.727-732
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    • 2001
  • The purpose of this study is to compare the time mean velocity distribution, the time mean kinetic energy, and the time mean turbulence intensity between vertical and horizontal flow fields in a coaxial circular pipe by PIV measurement. Experiments are performed at a Reynolds number 2,000, measuring regions divided as the section regions A, B, C, D in flow fields. The angle of the high-frequency ultrasonic is selected in the direction of $45^{\circ}$ to the flow axes and it is reflected several times. In results, it is clarified that the effect of gravity is given in the vertical flow field compared with the horizontal flow field and the ultrasonic affects the turbulence enhancement. And kinetic energy and turbulence intensity with ultrasonic are shown slightly bigger than those in flow field without it.

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An Study on the Transitional Flows in a Concentric Annulus with Rotating Inner Cylinder (안쪽축이 회전하는 환형관내 천이 유동 연구)

  • Hwang, Young-Kyu;Kim, Young-Ju
    • Proceedings of the KSME Conference
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    • 2001.06e
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    • pp.45-50
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    • 2001
  • This experimental study concerns the characteristics of a transitional flow in a concentric annulus with a diameter ratio of 0.52, whose outer cylinder is stationary and inner one rotating. The pressure losses and skin-friction coefficients have been measured for the fully developed flow of a 0.2 % aqueous solution of sodium carbomethyl cellulose (CMC) at a inner cylinder rotational speed of $0{\sim}600$ rpm. The transitional flow has been examined by the measurement of pressure losses, to reveal the relation of the Reynolds numbers with the skin-friction coefficients, in the laminar and transitional flow regimes. The occurrence of transition has been checked by the gradient change of pressure losses and skin-friction coefficient with respect to the Reynolds numbers. The increasing rate of skin-friction coefficient due to the rotation is uniform for laminar flow regime, whereas it is suddenly reduced for transitional flow regime and, then, it is gradually declined for turbulent flow regime. Consequently, the critical(axial-flow) Reynolds number decrease as the rotational speed increases. Thus, the rotation of inner cylinder promotes the early occurrence of transition due to the onset of taylor vortices.

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Effects of Casing Shape on the Performance of a Small-Size Turbo-Compressor (케이싱 형상 변화가 소형 터보압축기 성능에 미치는 영향)

  • 김동원;김윤제
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.14 no.12
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    • pp.1031-1038
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    • 2002
  • The effects of casing shape on the performance and interaction between the impeller and casing in a small-size turbo-compressor are investigated. Numerical analysis is conducted for the compressor with circular and single volute casings from inlet to discharge nozzle. In order to predict the flow pattern inside the entire impeller, vaneless diffuer and casing, calculations with multiple frames of reference method between the rotating and stationery parts of the domain are carried out. For compressible turbulent flow fields, the continuity and three-dimensional time-averaged Wavier-Stokes equations are employed. To evaluate the performance of two types of casings, the static pressure and loss coefficients are obtained with various flow rates. Also, static pressure distributions around casings are studied for different casing shapes, which are very important to predict the distribution of radial load. To prove the accuracy of numerical results, measurements of static pressure around casing and pressure difference between the inlet and outlet of the compressor are peformed for the circular casing. Comparisons of these results between the experimental and numerical analyses are conducted, and reasonable agreement is obtained.

A Study on Soil Reaction of Pile Fonndation Subjected to Dynamic Loading (동적 하중을 받는 말뚝기호의 지반반력에 관한 연구)

  • Kim, Young-Su;Lee, Song;Paik, Young-Shik
    • Geotechnical Engineering
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    • v.6 no.4
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    • pp.43-52
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    • 1990
  • To investigate the effects of soil properties of the soft zone around a pile subjected 1,o the horizontal harmonic vibration, the parametric study is perfomed. The determination of the soil reaction or stiffness of the Winkler springs representing the soil around a pile is performed by dividing the soil profile into a number of homogeneous obtained from this study are as follows : 1) The real and imaginary parts of the stiffness show clear variations for the different shear modulus ratios, poisson's ratios, and distance retios to outer boundary as the dimensionless frequency increases. The differences are more pronounced for the imaginary part of the stiffness. 2) The stiffness of soil shows clear decrease. The real parts of the stiffness show larger as the frequency increases. On the other hand, the imaginary parts of the stiffness show smaller.

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Ultrastructural Charateristics of a Human Sialolith (인간 타석의 미세구조적 특징)

  • Kim, Hyun-Jin;Lee, Soo-Guen;Suh, Bong-Jik
    • Journal of Oral Medicine and Pain
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    • v.24 no.4
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    • pp.375-385
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    • 1999
  • 타석에 관한 연구는 타석증을 보이는 환자에 대한 임상적 특징, 진단 및 치료에서부터 타석의 성분 및 구조 등에 이르기까지 다양한 범위에 걸쳐 이루어지고 있다. 타석의 미세구조에 관한 연구는 타석의 미세구조가 다양한 형태인 것으로 보고되고 있으며, 특히 최근 타석증의 치료에 새롭게 소개되고 있는 체외충격파쇄석술은 타석의 구조에 따라 그 효과가 영향을 받을 수 있을 것으로 사료된다. 이에 저자는 인간 타석의 미세구조에 관한 기본 자료가 필요할 것으로 사료되어 한국인 중년 여성으로부터 적출된 악하선 타석을 광학현미경 및 주사전자현미경을 이용하여 미세구조적 특징을 관찰한 결과, 다음과 같은 결론을 얻었다. 1. 타석은 중심부의 핵, 핵 주변의 층상구조 및 외피막으로 이루어져 있었다. 2. 핵은 비정형의 중심과 상대적으로 균질의 외곽부위로 구성되어 있었다. 3. 핵 주변은 대부분 동심원적인 층상구조를 보였지만 일부분에서는 균질의 구조를 보였다. 4. 타석 단면의 전체직경과 중심부 핵의 직경은 각각 $3,500{\mu}m$$1,500{\mu}m$였고, 층상구조를 이루는 각 층의 두께는 위치에 따라 약 $10{\sim}40{\mu}m$ 이내였다.

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