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Anti-inflammatory Activity of Crinum asiaticum Linne var. Japonicum Extract and its Application as a Cosmeceutical Ingredient (문주란의 항염효과와 화장료적 특성)

  • Kim, Ki-Ho;Kim, Young-Heui;Kim, Ki-Soo;Park, Sun-Hee;Lee, Soo-Hee;Kim, Young-Jin;Kim, Young-Sil;Kim, Jong-Heon
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.32 no.1 s.55
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    • pp.59-64
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    • 2006
  • Crinum asiaticum Linne var. japonicum has long been used as a rheumatic remedy, an anti-pyretic, an anti-ulcer treatment, and for the alleviation of local pain and fever in Korea and Malaysia. In order to investigate the possibility of Crinum asiaticum Linne var. japonicum extract as a cosmetic ingredient, we measured its anti-inflammatory effect by inhibition of iNOS (inducible nitric oxide synthase), and the release of PGE2, IL-6, and IL-8. HPLC experiment after extraction with 95% ethanol at pH 3.5 showed that Crinum asiaticum Linne var. japonicum was mainly composed of lycorine (up to 1%), a well-known immunosuppressant. The content of lycorine varied depending on the type of tissue analyzed and the extraction method. In anti-inflammatory assay for inhibition of nitric oxide formation on lipopolysaccharide (LPS)- activated mouse macrophage RAW 264.7 cells, the ethanolic extract of Crinum asiaticum showed inhibitory activity of NO production in dose-dependent manner ($IC_{50} = 83.5 {\mu}g/mL$). Additional study by RT-PCR demonstrated that the extract of Crinum asiaticum significantly suppressed the expression of the iNOS gene. Moreover, the extract of Crinum asiaticum did not show my cytotoxicity, but did show cell proliferation effect against LPS ($10{\sim}60%$ increase of tell viability). In an assay to determine inhibition of the $H_2O_2$-activated release of PGE2, IL-6, and IL-8 in human normal fibroblast cell lines, the release of PGE2 and IL-6 was almost completely inhibited above concentrations of 0.05% and 1%, respectively. Moreover, the release of IL-8 was completely inhibited over the entire range of concentrations (> 0.0025%). The result showed that the extract of Crinum asiaticum Linne var. japonicum has sufficient anti-inflammatory effect. There-fore, Crinum asiaticum Linne var. japonicum extract may be useful as an ingredient of cosmetic products.

Shallow Subsurface Structure of the Yaksoo Area, Ulsan, Korea by Geophysical Surveys (물리탐사기법에 의한 울산광역시 약수지역 천부지하구조 조사)

  • Lee, Jung-Mo;Kong, Young-Sae;Chang, Tae-Woo;Park, Dong-Hee;Kim, Tae-Kyung
    • Journal of the Korean Geophysical Society
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    • v.3 no.1
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    • pp.57-66
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    • 2000
  • The location and geometry of the Ulsan Fault play important roles in interpreting tectonic evolution of the southeastern part of the Korean Peninsula. Dipole-dipole electrical resistivity surveys and seismic refraction surveys were carried out in the Yaksoo area, Ulsan in order to measure the thickness of the alluvium covering the Ulsan Fault and to find associated fracture zones and possibly the location of its major fault plane. The collected data were analyzed and interpreted. Some results reported previously by others were also used in this interpretation. No low resistivity anomalies were found in the cross-sectional resistivity image of the survey line located in the east of the Dong River. In contrast, well-developed continuous low resistivity anomalies were detected in the west of the Dong River. This strongly suggests that the major fault plane of the Ulsan Fault is located under or in the west part of the Dong River. Two refraction boundaries corresponding to the underground water level and the bottom of the alluvium were found by refraction surveys carried out on the limited part of the east survey line. The thickness of the alluvium was found to be about 30 m. Small faults in the basement rock identified by reflection surveys were not detected by both resistivity and refraction seismic surveys. This might be explained by assuming that low resistivity anomaly is more closely related to the clay contents than the water contents. On the other hand, it may be resulted by the limited resolution of the resistivity and refraction surveys. Detailed study is required to clarify the reason. Resistivity survey is frequently considered to be a good exploration method to detect subsurface faults. However, it appears to be less useful than reflection seismic survey in this work. In dipole-dipole resistivity survey, the number of separation should be increased to survey deeper subsurface with the same resolution. However, signal to noise ratio decreases as the number of separation increases. In this survey area, the signal to noise ratio of up to sixteen separations was good enough based on the statistical properties of measurements.

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Geological structure of the Ogcheon metamorphic zone in the Busan areal Korea: a new geodynamic model to the Heart-shaped Busan gneiss complex (부산지역에서 옥천변성대의 지질구조: 하트상 부산 편마암복합체에 대한 새로운 지구조모델)

  • 강지훈
    • The Journal of the Petrological Society of Korea
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    • v.10 no.2
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    • pp.106-120
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    • 2001
  • The Busan area in the northeastern part of the Ogcheon metamorphic zone, Korea, consists mainly of Precambrian Busan and Bakdallyeong gneiss complexes, Ogcheon metamorphic rocks and Mesozoic granitoids. The Busan gneiss complex shows Heart-shaped distribution laying down eastward, and is surrounded by the Ogcheon metamorphic rocks in the central part of the Busan area. In this study structural examination on the main constituent rocks (Busan gneiss complex and Ogcheon metamorphic rocks) was conducted to clarify the geological structure of the Ogcheon metamorphic zone in the Busan area. It indicates that the geological structure was formed at least by three phases of deformation. (1) Dl deformation: the formative period of the structural units of WNW trend (Sanjeoteo, Busan-II, Busan-I, and Chungiu nappes) and the mylonitic foliations related to the compression of NNE-SSW direction, (2) D2 deformation: the differential E-W shortening and N-S extension period of the structural units of WNW trend related to the compression of E-W or WNW-ESE directions, (3) D3 deformation: the formative period of the kink or open folds of E-W trend related to the compression of N-S direction in the eastern and southern parts of Busan area where the structural units of N-S or NNE trends reoriented owing to the intense D2 deformation were developed. These three phases of deformation are closely connected with the distribution of the structural units and the Heart-shaped Busan gneiss complex laying down eastward, and in this paper a new geodynamic model to the Heart-shaped Busan gneiss complex is suggested: Dl deformation-the zonal distribution of WNW trend with a constant width, D2 deformation - the formation of convex wedges northeastward and southward, D3 deformation - the formation of concave wedge westward.

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Igneous Activity and Geological Structure of the Ogcheon Metamorphic Zone in the Kyemyeongsan area, Chungju, Korea (충주 계명산지역 옥천변성대의 화성활동과 지질구조)

  • 강지훈;류충렬
    • The Journal of the Petrological Society of Korea
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    • v.6 no.3
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    • pp.151-165
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    • 1997
  • The Kyemyeongsan area of Chungju in the NE part of the Ogcheon metamorphic zone, Koera, consists mainly of the Ogcheon Supergroup(Taehyangsan Quartzite, Hyangsanri Dolomite and Kyemyeogsan Formation) and the MeSozoic Chungju granite. The Kyemyeongsan Formation is composed mainly of metamorphic rocks of various grades derived from conglomeratic, basic, acidic, pelitic and psammitic rocks. The basic and acidic rocks show alternated or interfingered appearence, indicating that they were derived form bimodal type of magmatism in rift environment. Conglomeratic rocks overlie acidic volcanic rocks in geneal, but are underlain by both acidic plutonic and volcanic rocks. This indicaties that the acidic magmatism before the formation of conglomeratic rocks was different from that during or after the formation of conglomeratic rocks in its occurrence mode. The geological structure of the Ogcheon metamorphic zone in the Kyemyeongsan area, Chungju was formed at least by three phases of deormation. The first phase deformation(D1) formed a regional-scale sheath-type fold(F1) closed into the east. Its axial phane(S1) strikes NNW to NW and dips WSW to SW. The stetching lineation(L1), related to the sheath-type fold, plunges westward. The second phase deformation (D2) formed asymmetric fold(F2) of ESE-to SE-vergence with NNE to NE striking axial plane(S2) and $20~45^{\circ}/210~230^{\circ}$ plunging axis(L2). The F2 fold reoriented the original westward plunging L1 into northwestward plunging L1 in its lower limb(overturned limb). The third phase of deformation(D3) was recognized as chevron-type fold(F3) with $45^{\circ}/265$^{\circ}$ plunging axis. The F3 fold was formed by the compression of N-S direction, resulting in the reorientation of the original $20-45^{\circ}/210~230^{\circ}$ plunging L2 into mainly $35~45^{\circ}/260~280^{\circ}$ and subsidiarily $30~45^{\circ}/135~165^{\circ}$ plunging L2. After this deformation, open fold with NS striking and steeply E or W dipping axial plane is formed by the compression of E-W direction.

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Block Tectonics of The Taebaegsan Basin and En Echelon Sedimentary Wedges of The Yeonhwa-Ulchin District, Mideastern South Korea

  • Yun, Suckew
    • Economic and Environmental Geology
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    • v.11 no.4
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    • pp.127-141
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    • 1978
  • The major structures characteristic of the Taebaegsan sedimentary basin were regionally analyzed with special reference to its southeastern extension to the Yeonhwa-Ulchin district of economic interest in zinc-lead mineralization. The basin geometry, basement setting, sedimentary components, and the characteristics of deformation and igneous activity of the Taebaegsan basin differ basically from those of the adjacent mobile belt of the Ogcheon geosyncline, although the latter affected the basin's western side considerably. The subrectangular shape of the Taebaegsan basin reflects the checkered pattern of basement-block arrangement, and the carbonate-dominated lithologic components of the basin-fill indicate a cratonic depositional setting, which is comparable to some of the North American mid-continental craton. The Taebaegsan basin, however, has somewhat been less stable than the North American megacraton that is reflected in the former's thicker sedimentary fill and steeper faults of later deformation, showing a tendency to increase in thickness close to the basement-block boundaries, which may indicate contacts of possibly detached cratonic blocks of Precambrian age; these weak zones of block boundaries have been the loci of repeated sedimentation, deformation and related igneous intrusions. A series of downthrown or uplifted tilted blocks, in which the Cambro-Ordovician sedimentary wedges and the late Cretaceous to early Tertiary igneous intrusives are involved, occurs intermittently across the Yeonhwa-Ulchin district in a noticeable pattern of en echelon type. These sedimentary wedges are correlated to the Cambro-Ordovician section of the Hambaeg syncline to the west in stratigraphy and lithology, and are considered to have resulted from the northeastern and/or northwestern cross-faulting of the pre-existing syncline belt of easterly trend, extended from the main portion of the Hambaeg syncline. These structural junctions (or intersections) of the earlier syncline belt and the later cross-faults have been acted as a guide to ascending igneous materials and hydrothermal ore-forming fluids to form a zone of zinc-lead skarn deposits across the Yeonhwa-Ulchin district showing a stepwise recurrence of these deposits toward the east.

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Habitat Distribution Change Prediction of Asiatic Black Bears (Ursus thibetanus) Using Maxent Modeling Approach (Maxent 모델을 이용한 반달가슴곰의 서식지 분포변화 예측)

  • Kim, Tae-Geun;Yang, DooHa;Cho, YoungHo;Song, Kyo-Hong;Oh, Jang-Geun
    • Korean Journal of Ecology and Environment
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    • v.49 no.3
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    • pp.197-207
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    • 2016
  • This study aims at providing basic data to objectively evaluate the areas suitable for reintroduction of the species of Asiatic black bear (Ursus thibetanus) in order to effectively preserve the Asiatic black bears in the Korean protection areas including national parks, and for the species restoration success. To this end, this study predicted the potential habitats in East Asia, Southeast Asia and India, where there are the records of Asiatic black bears' appearances using the Maxent model and environmental variables related with climate, topography, road and land use. In addition, this study evaluated the effects of the relevant climate and environmental variables. This study also analyzed inhabitation range area suitable for Asiatic black and geographic change according to future climate change. As for the judgment accuracy of the Maxent model widely utilized for habitat distribution research of wildlife for preservation, AUC value was calculated as 0.893 (sd=0.121). This was useful in predicting Asiatic black bears' potential habitat and evaluate the habitat change characteristics according to future climate change. Compare to the distribution map of Asiatic black bears evaluated by IUCN, Habitat suitability by the Maxent model were regionally diverse in extant areas and low in the extinct areas from IUCN map. This can be the result reflecting the regional difference in the environmental conditions where Asiatic black bears inhabit. As for the environment affecting the potential habitat distribution of Asiatic black bears, inhabitation rate was the highest, according to land coverage type, compared to climate, topography and artificial factors like distance from road. Especially, the area of deciduous broadleaf forest was predicted to be preferred, in comparison with other land coverage types. Annual mean precipitation and the precipitation during the driest period were projected to affect more than temperature's annual range, and the inhabitation possibility was higher, as distance was farther from road. The reason is that Asiatic black bears are conjectured to prefer more stable area without human's intervention, as well as prey resource. The inhabitation range was predicted to be expanded gradually to the southern part of India, China's southeast coast and adjacent inland area, and Vietnam, Laos and Malaysia in the eastern coastal areas of Southeast Asia. The following areas are forecast to be the core areas, where Asiatic black bears can inhabit in the Asian region: Jeonnam, Jeonbuk and Gangwon areas in South Korea, Kyushu, Chugoku, Shikoku, Chubu, Kanto and Tohoku's border area in Japan, and Jiangxi, Zhejiang and Fujian border area in China. This study is expected to be used as basic data for the preservation and efficient management of Asiatic black bear's habitat, artificially introduced individual bear's release area selection, and the management of collision zones with humans.

Ecological Risk of Alien Apple Snails Used in Environmentally-friendly Agriculture and the Urgent Need for Its Risk Management in Korea (친환경농법용 외래 왕우렁이의 생태위해성 및 위해성 관리의 필요성)

  • Bang, Sang-Weon;Cho, Mi-Kyeoung
    • Korean Journal of Environmental Biology
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    • v.26 no.3
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    • pp.129-137
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    • 2008
  • Alien apple snails (Pomacea canaliculata, Pomacea insularus) used in environmentally-friendly agriculture are different from indigenous snails found in Korea. Due to high herbicidal effects and cost-effectiveness, the number of farmers using the snails has been growing every year since 2000. Moreover, in 2008, because of the outbreaks of avian influenza throughout the country from March to May, 2008, central and local governments recommended the use of alien apple snails in agriculture as an alternative to the ducks-oriented environmentally-friendly agriculture. Therefore, it is expected that the use of alien apple snails in agriculture should be expanded in a near future. Since alien apple snails lay eggs with 95.8% of eclosion rate, they are considered to be potential pests unlike indigenous snails. In addition, Japan, Taiwan and most of the southeast Asian countries had already experienced severe ecological and agricultural damage by the alien apple snails. Subsequently, International Union for Conservation of Nature and Natural Resources (IUCN) designated P. canaliculata as one of "the 100 of the world's worst invasive alien species". It seems highly likely that the alien apple snails in Korea pose a potential threat to conservation of ecosystem and biodiversity since the snails were either found or invaded into the natural environments in some regions of Gangwon-Do and southern parts of Korean Peninsula. However, just recently, agricultural authorities and farmers using alien apple snails in agriculture opposed a proposition of designating the alien apple snails as an ecosystem-disturbing animal described by the Wildlife Protection Act. This is because there has been no concrete evidence of the ecological risk imposed by the alien snails up to now in Korea. Subsequently, in this paper, we analysed the ecological and agricultural risks imposed by the alien snails from the studies done in domestic and abroad. In addition, we proposed an urgent need and reasoning for ecological risk management of the alien snails at the national level as well as using the snails in agriculture.

Studies on the Seedling Production of the Freshwater Crab, Eriocheir japonicus (De Haan) 4. Combined Effects of Temperature-Salinity on the Moulting Intervals of Larvae (동남참게, Eriocheir japonicus (De Haan)의 종묘생산에 관한 생물학적 기초연구 4. 성장단계별 유생에 대한 脫皮 간격일수에 미치는 수온-염도의 복합적인 영향에 관하여)

  • KWON Chin-Soo;LEE Bok-Kyu
    • Journal of Aquaculture
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    • v.7 no.1
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    • pp.21-39
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    • 1994
  • In order to study the optimum environmental condition for larvae culture of the freshwater crab, Eriocheir japonicus, larvae from different growth stages and young crab were cultured under the 16 different conditions of $4\times4$ temperature-salinity combinations (4 different temperatures at 22, 24, 26, $28^{\circ}C$ with 10.5, 17.5, 24.5 and $31.5\%$ of salinity). The duration of metamorphosis, metamorphosis rate, the interval of moulting period, and survival rate were measured from each experimental group of larvae and young crab under the different conditions. The results indicated that the optimum conditions may be a $24.5\%o$ of salinity at water temperature at 22, 24, and $26^{\circ}C$. At $28^{\circ}C$ with $24.5\%o$), the duration of metamorphosis reduced somewhat, nevertheless metamorphosis and survival rate decreased a lot. And the lower the salinity showed the lower the metamorphosis and survival rates at $28^{\circ}C$.

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A Study on the Meaning and Types of Banpo [斑布] during the Joseon Dynasty (조선시대 반포(斑布)의 의미와 형식 연구)

  • Ree, Jiwon
    • Korean Journal of Heritage: History & Science
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    • v.53 no.3
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    • pp.164-183
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    • 2020
  • In the textile culture of the Joseon Dynasty, the historic record of Banpo is fragmentary and contains many missing details. The main reason is a lack of associated literature, and it is also significant that the actual substance used is not clear at present. Banpo is a kind of cotton, but this has not been confirmed in the traditional textiles that are currently handed down. The word Ban [斑] in Banpo means "stain", and the letter Po [布] means "fabric". At the border of white discourse, Banpo did not receive attention as a research topic. This study is an attempt to restore some of the textile culture of the Joseon Dynasty through Banpo. Banpo is not just limited to the Joseon Dynasty; it is an important material for examining the development of textile culture and exchange in East Asia. This study was broadly divided into three parts. First, the record and meaning of Banpo during the Joseon Dynasty were examined. Records of Banpo can be seen from the early Joseon period during King Sejo and Seongjong, and the production and actual use of Banpo have been confirmed. Banpo was maintained until the beginning of the 20th century, but is no longer observed. Banpo is a woven fabric made of cotton yarn dyed in many colors and has appeared in Southeast Asia since ancient times. In East Asia, there are other fabrics similar to Banpo, such as Ho [縞], Sum [纖], and Chim [綅]. In particular, the correlation between Banpo and Ho is an important link in understanding Banpo in the Joseon Dynasty. Second, the meaning of Banpo was examined from various angles through comprehensive analysis of Chinese and Japanese literature records and cases. The appearance and development of Banpo moved in sync with the period when cotton was introduced into East Asia. In East Asia, cotton was introduced and produced in earnest from the end of the Song Dynasty to the beginning of the Yuan Dynasty, and the meaning of Banpo was diversified. In China, the name of Banpo was changed to Hwapo [花布], Gizapo [碁子布], Gizahwapo [棋子花布], etc. Japan was late to introduce cotton and developed it in acceptance of the changed meaning. In Japan, use of the name Banpo is not on record, but a Ryujo [柳條] fabric of the same type as banpo has been identified. This Ryujo is the same concept as Ho and Hwapo, and later merged into Ho. Names such as Ho, Hwapo, Banpo, etc. were used differently in each country, but the form was shared across East Asia. Third, based on the meaning of Banpo shared in East Asia, the format of Banpo in the Joseon Dynasty was classified. The format of Banpo in the Joseon Dynasty can be divided into grid and striped versions. The name Banpo disappeared over time, but the form remained and was passed down until recently. I hope that this study will help restore Banpo in the future.

Research on Methods of Developing Quadrangular Culm of Bamboos (사각죽조성(四角竹造成)에 관(關)한 연구(硏究))

  • Chong, Hyon-Pae
    • Journal of Korean Society of Forest Science
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    • v.10 no.1
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    • pp.7-16
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    • 1970
  • There are 19 species of bamboo in Korea, among which few are of commercial value. The Phyllostachys has wide range of utilization, for sea weed production, industrial production of various bamboo wares, etc. The total export from Chenla-Namdo to some more than ten countries was recorded 204,000,000 won worth in 1969. As civilization develops so does the techniques of bamboo works, and they in turn accelerate the demand for bamboo wood of better quality. In the light of this trend, the author attempted to make bamboo plants to develope a quadragular culm with elaborate design as disired instead of the original round one, with the expectation that it might be widely welcomed by hand workers, interior decorators. Here are some facts found out in this experiment: 1). The greater the diameter of the shoot at the eye level was, the better result was brought, and as shown in Fig. 5 the rate of success was 72% with the shoots of 7.5 cm thick. 2). The shoots of 30 cm in length showed 100% of success, developing into a desired quadrangular culms without fail(See Fig. 6). 3). The intensity of wood fiber increased as time lapsed, without receiving any influence by the weather (See Fig. 7, 8). 4). During the growing, the culm proved to be flexible enough to bend up to 90 degree (See Fig. 9). 5). In an attempt to promote the value of bamboo by decoration, the author tried to impress rectangular indents on the culm. The indention using a qudangular board 1cm smaller in width than the shoot diameter gave 100% success (See Fig. 10). 6). Design experiment was also successful both in coloration and impressing and the resulting designs delicately depended on the kinds of chemicals used and their combination (Table 2) (See Fig. 12, 13, 14). With the above mentioned findings, the author concludes that the mass production of quadrangular bamboo culm is quite a promissing as an new industry to develope bamboo works to a more valuable one. This research was carried out with the research fund provided by the Ministry of Education in 1969.

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