• Title/Summary/Keyword: 대상체

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항암성 N-arylsulfonylimidazole 유도체의 합성

  • 정상헌
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 1994.04a
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    • pp.224-224
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    • 1994
  • N-arylsulfonylimidazolenes를 항암효과가 우수한 화합물로 설정하여 이들 유도체를 합성하고 이들의 세포독성을 측정한바 있다. 그 이유는 2번 위치의 alkoxy기에 의하여 alkylating agent로서 작용할 수 있다는 개념과 생체 반응 후 생성될 것으로 예상되는 N-arylsulfonylimidazolidinone이 sulofenur와 유사한 작용을 갖을 것으로 기대 되었기 때문이다. 이에따라 N-arylsulfonylimidazolidinone 유도체의 항암효과의 측정이 관심의 대상이 됨에 따라 이들 유도체를 합성하고 이들의 세포독성을 관찰함으로써N-arylsulfonylimidazolidinone 유도체들의 구조 활성 상관관계를 관찰하고자 하였다. 합성은 출발물질을 N-arylsulfonyl-2-alkoxyimidazoline에서 시작 몇단계를 거쳐 목적하는 화합물을 합성 하였다.

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Evaluation of the Translation Part of the Concept-based Spoken Language Translation System (개념기반 대화체 언어번역시스템의 번역부평가)

  • Choi, Un-Cheon;Han, Nam-Yong;Kim, Jae-Hoon
    • Annual Conference on Human and Language Technology
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    • 1996.10a
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    • pp.322-325
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    • 1996
  • 이 논문은 개념기반의 대화체 언어번역시스템의 번역부의 평가에 대해 기술한 것이다. 대상언어는 한국어와 영어로 한국어를 해석하여 영어로 번역하는 시스템이다. 개념기반 시스템은 개념을 기준으로 입력된 문장을 해석하고 그 개념을 이용하여 번역한다. 개념기반 시스템은 개념에 기반을 두기 때문에 자유로운 간투사의 사용, 빈번한 단어 생략 등의 특성을 가지는 대화체 번역에 유리하다. 시스템의 평가는 입력문에 대한 번역문의 결과가 의미적으로 어느 정도 전달되었는지를 평가자의 주관적인 판단에 의해 평가한다. 현재 개발된 시스템은 여행안내 영역(domain)을 대상으로 하고 있다. 개발된 시스템에 대한 평가는 대화체를 전사한 문장과 음성인식의 결과 두 가지의 입력에 대해 하였다.

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The Opinion Trend of Members of the Forest Management Cooperatives Concerning Its Management (산림경영협업체(山林經營協業體) 운영(運營)에 관(關)한 회원(會員)의 의식동향(意識動向))

  • Kang, Hag Mo;Kang, Sung Yun;An, Jong Man;Lee, Sang Hyun
    • Journal of Korean Society of Forest Science
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    • v.86 no.2
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    • pp.233-240
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    • 1997
  • This study was carried out to investigate members' affiliation motive to Forest Management Cooperative which is the main managemental body of the private forests and management problems of the organization to find out a solution of the problems and set active promotion plan. The questionnaire about the management of the cooperatives was done by interviewing the members at Seoha Inboh Forest Management Cooperative in Ulsan-gun, Kyongsangnam-do and Sechong Forest Management Cooperative in Chinan-gun, Chollabuk-do from July to August in 1993. Twenty interviewees were selected in the order of their business quantity on the forest from the members who reside in their villages. Integrated matters such as were members' affiliation motive, benefit after their affiliation, management system, incorporation of the organization and other issues concerning to managemental plans questioned. During the survey period, other data about management of the cooperatives were collected from the related organizations and opinions of every president of nine cooperatives in the investigated regions. The majority of the members agreed that the cooperative is an independent forest organization and evaluated the Training and Extension Service Center high. However, their participations in the cooperative such as forest technical training and cooperative forest management were low since they have not earned any income from their forest management.

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A Characterization of Isomorphism Problem of Combinatorial objects and the Historical Note (조합대상의 동형사상 문제의 특성화와 역사적 고찰)

  • Park, Hong-Goo
    • Journal for History of Mathematics
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    • v.19 no.1
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    • pp.33-42
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    • 2006
  • In this paper, we study the theoretical and historical backgrounds with respect to isomorphism problem of combinatorial objects which is one of major problems in the theory of Combinatorics. And also, we introduce a partial result for isomorphism problem of Cayley objects over a finite field.

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Mechanical Anisotropy of Jurassic Granites in Korea (국내 주라기 화강암의 역학적 이방성)

  • 서용석;박덕원
    • The Journal of Engineering Geology
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    • v.13 no.2
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    • pp.257-266
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    • 2003
  • Jurassic granites of three sites, Pocheon, Geochang and Habcheon, were tested to investigate the effect of microcracks on Physical and mechanical properties of the granites. Fifteen oriented core specimens were used for the physical property test. The test result shows that porosity is almost proportioned to water content. P-wave velocity is the highest in the direction of axis ‘H’, intersection of two major microcrack sets and the lowest in the axis ‘R’, normal to the rift plane. Compressional strength tests were carried out for each core specimen taken parallel with axes ‘R’, ‘G’ and ‘H’, measuring strains. The results revealed a strong correlation between microcrack orientation and other mechanical properties such as rock strength.

베타수용체의 추출 및 1차정제

  • 고광호;신찬영;강현삼
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 1992.05a
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    • pp.26-26
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    • 1992
  • 신경계의 수용체 중에서 카테콜아민 신경계의 작용을 매개하는 수용체에는 $\alpha$-, $\beta$-, D-수용채 등이 있으며 카테콜아민 신경계의 활성변화를 유발시켜 인위적으로 생리현상 변화를 초래할 목적으로 사용되는 각종 의약품 등의 효능도 결국 체내에서 이들 수용체를 경유하여 발현된다는 사실들이 밝혀지고 있다. 신약대상물질의 신속한 효능검색 이외에 수용체를 활용해야 하는 중요한 신약개발 연구는 수용체의 구조 파악과 수용체와의 결합력을 근간으로 하여 신약의 기본구조에 접근하는 방식이다. 이러한 연구에서 소기의 성과를 얻기 위해서는 수용체의 추출, 정제, 특성파악, 수용체-신호전달 체계의 상관성, 수용체 관련 질병의 분류, 수용채의 클로닝 및 대량생산 등이 동반 수행되어야 한다.

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Punching Shear Performance Evaluation of Foundation by Enforcement-length of Shear Head Reinforcement (전단 보강재의 보강길이에 따른 기초판의 뚫림전단 성능평가)

  • Lee, Yong-Jae;Yi, Waon-Ho;Yang, Won-Jik
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.21 no.2
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    • pp.60-68
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    • 2017
  • This study was made to examine the motion characteristics according to the reinforcement of the reinforcement length and stiffener reinforcement for shear reinforcement to the foundation structure reinforced with shear reinforcement steel plate. Experimental study was made after specimen was installed on the ground as the same as in the practical site. Reinforcement lengths of the steel for shear reinforcement are divided into 1,000 mm, 1,200 mm and 1,400 mm in the specimen and as for reinforcement method of the stiffener, 4 stiffeners with interval of 100mm reinforced with the same materials as the shear reinforcement were manufactured for the experiment. Considering result of the experiment, it is expressed that no effect of the stiffener reinforcement was found and regarding the reinforcement length of shear reinforcement material the crossed point of the two converted lines of the value that the shear force is expressed in the bearing power in the expanded dangerous section and the value that the shear capacity receivable by the reinforcement materials in the dangerous section is proposed as effective reinforcement length.

Comparison between Congestion Levels and Amount of $CO_2$ Emissions on Arterials (단속류 간선도로에서 지정체와 $CO_2$ 배출량 비교)

  • Gang, Jin-Gu;O, Heung-Un
    • Journal of Korean Society of Transportation
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    • v.29 no.6
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    • pp.17-23
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    • 2011
  • It has been presumed that the amount of vehicle's $CO_2$ emission would highly related to vehicle's cruising speeds on highways. In this study, it was tested if vehicle's $CO_2$ emissions would relate to the types of highways and the level of congestion. The results showed that the amount of $CO_2$ emission changes depending on (1) the vehicles' cruising speeds (b) congestion levels, and (c) the types of intersections. It was found that the vehicle acceleration and deceleration methods increases the amount of $CO_2$ emission up to 12%. It was also found that it changed up to 30% and 40% depending on the level of congestion and the types of intersections, respectively. The findings imply that the amount of $CO_2$ emission from vehicles should be improved when vehicles' cruising speeds are well managed through congestion management.

In-vivo Measurement of Cucumber to Detect N-Deficient Stress (오이의 질소결핍 장해 진단을 위한 생체정보 수집)

  • 성제훈;류육성;서상룡;정갑채
    • Proceedings of the Korean Society for Agricultural Machinery Conference
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    • 1999.07a
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    • pp.171-176
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    • 1999
  • 작물의 생육장해 진단은 식물체의 계측에 의해 수행되는데, 이러한 계측은 생육 중인 작물을 대상으로 할 경우, 작물의 잎이나 줄기의 비파괴적 생체(in-vivo)계측을 필요로 하며 비접촉이면 더욱 바람직하다. 그리고 식물체의 건강상태를 좀더 신속하고 정확히 파악하기 위해서는 가능한 다양한 항목을 측정 대상으로 하여 관찰하는 것이 요구될 뿐만 아니라 많은 경우 그 관찰은 미소한 생장반응 및 생장량을 측정하여야 하므로 상당히 높은 정확도의 전문 센서가 필요하다. (중략)

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