• Title/Summary/Keyword: 단계선택법

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Current research trends of analytical methods for non-nutritive sweeteners (Non-nutritive sweeteners 분석을 위한 최근 분석기술 동향)

  • Yun, Choong-In;Kim, Young-Jun
    • Food Science and Industry
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    • v.55 no.1
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    • pp.58-73
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    • 2022
  • Due to the recent demand for low-calorie foods, consumers are looking for alternative sweeteners that can control blood sugar, low risk of tooth decay and low calories. Regulations for permitted sweeteners in food vary from every country, and it is important for the government and the food industry to monitor products containing these sweeteners to ensure global compliance. Therefore, rapid, precise, and accurate analysis for food matrices should be applied to quality control, market surveillance, monitoring, and evaluation of food additive intake in the food industry. To analyze sweeteners simultaneously, it is essential to develop an efficient and rapid analytical method and to perform appropriate pretreatment steps such as solvent extraction and purification. This study presented the recent analysis trends about the suitable extraction method for food matrices focusing on non-nutritive sweeteners. Additionally, techniques for multi-compounds analysis using HPLC and LC-MS/MS and non-destructive analysis techniques using FT-IR were comprehensively described.

Simultaneous determination of amphetamine derivatives and norketamine in hair by GC-MS/MS (GC-MS/MS를 이용한 모발 중 암페타민 유도체 및 노르케타민 동시분석)

  • Kim, Jin Young;Shin, Soon Ho;Ko, Beom Jun;Chung, Jae Cheol;Suh, Yong Jun;In, Moon Kyo
    • Analytical Science and Technology
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    • v.22 no.3
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    • pp.210-218
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    • 2009
  • A gas chromatography-tandem mass spectrometry (GC-MS/MS) method was developed and validated for simultaneous determination of amphetamine derivatives and norketamine in human hair. Preparation of hair involves external decontamination, mechanical pulverization, incubation and extraction prior to instrumental analysis. The samples were derivatized using heptafluorobutyric anhydride, and analyzed by GC-MS/MS. The linear ranges were 0.05-20.0 ng/mg for the analytes except for 3,4-methylenedioxyamphetamine, with good coefficients of determination ($r^2$ >0.998). The intra-day and inter-day precisions were within 10.7% and 8.5%, respectively. The intra-day and inter-day accuracies were between -1.6 and 17.0% and -2.6 and 10.5%, respectively. The limits of detections for each analyte were lower than 0.007 ng/mg, while recoveries were 75.9-100.9%. When the method was applied to hair samples obtained from suspected drug abusers, the concentrations in hair samples were 0.97-19.30 ng/mg for methamphetamine and 0.14-2.56 ng/mg for amphetamine.

Intra-laboratory Validation of an HPLC Post-column Oxidation Method for the Analysis of PSP Toxins in Oysters and Mussels (굴과 진주담치 중 마비성 패류독소 분석을 위한 HPLC post-column oxidation method의 시험소 내 유효성 검증)

  • Song, Ki Cheol;Lee, Ka-Jeong;Yu, Hong-Sik;Mok, Jong-Soo;Kim, Ji Hoe;Lim, Keun-Sik;Lee, Mi-Ae;Kim, Mee-Hye
    • Korean Journal of Food Science and Technology
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    • v.45 no.2
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    • pp.241-247
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    • 2013
  • AOAC Mouse Bioassay Analysis (MBA) has been the gold standard for the analysis of paralytic shellfish poisoning toxin (PSP toxin) for more than 50 years. However, this method has inaccurate limit of quantification and cannot be used to determine toxic profiles. An HPLC method (PCOX) was optimized for Korean shellfish to establish an alternative or supplementary method for PSP analysis and was intended to be used for the official monitoring and regulation of food. The recovery rate of the PCOX method was 83.5-112.1% and the limit of quantification for total toxin was about $8.6{\mu}g$/100 g. A long-term comparison study showed a good correlation of the PCOX results with the AOAC MBA results: the correlation factors were 0.9534 and 0.9109 for oyster and mussel matrices, respectively. The PCOX method may be used as an alternative or supplementary method for AOAC MBA to monitor the occurrence of PSP and to analyze PSP toxin profile in oysters and mussels.

A Robust Design of Response Surface Methods (반응표면방법론에서의 강건한 실험계획)

  • 임용빈;오만숙
    • The Korean Journal of Applied Statistics
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    • v.15 no.2
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    • pp.395-403
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    • 2002
  • In the third phase of the response surface methods, the first-order model is assumed and the curvature of the response surface is checked with a fractional factorial design augmented by centre runs. We further assume that a true model is a quadratic polynomial. To choose an optimal design, Box and Draper(1959) suggested the use of an average mean squared error (AMSE), an average of MSE of y(x) over the region of interest R. The AMSE can be partitioned into the average prediction variance (APV) and average squared bias (ASB). Since AMSE is a function of design moments, region moments and a standardized vector of parameters, it is not possible to select the design that minimizes AMSE. As a practical alternative, Box and Draper(1959) proposed minimum bias design which minimize ASB and showed that factorial design points are shrunk toward the origin for a minimum bias design. In this paper we propose a robust AMSE design which maximizes the minimum efficiency of the design with respect to a standardized vector of parameters.

Application of Flipped Learning in Database Course (데이터베이스 교과목에서 플립러닝 적용 사례)

  • Kim, Eun-Gyung
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.20 no.4
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    • pp.847-856
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    • 2016
  • Flipped learning is a pedagogic model in which the typical lecture and homework elements of a course are reversed. Short video lectures or e-learning contents or other learning materials are viewed by students at home before the in-class session, while students are mainly carried out diverse active learning activities such as the discussions, exercises, team projects and so on in class time. Recently flipped learning has been emerging as an effective teaching-learning method that can train the 21st century talents who can create creative values based on fusion competencies. Based on the experience in applying the flipped learning to the database class that is an elective course of the school of computer engineering through three semesters, this paper proposes a flipped learning model consists of 7 steps in detail. Also, this paper analyzes the effects and weak points of the flipped learning and proposes several things for the successful flipped learning application.

Automatic Face Extraction with Unification of Brightness Distribution in Candidate Region and Triangle Structure among Facial Features (후보영역의 밝기 분산과 얼굴특징의 삼각형 배치구조를 결합한 얼굴의 자동 검출)

  • 이칠우;최정주
    • Journal of Korea Multimedia Society
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    • v.3 no.1
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    • pp.23-33
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    • 2000
  • In this paper, we describe an algorithm which can extract human faces with natural pose from complex backgrounds. This method basically adopts the concept that facial region has the nearly same gray level for all pixels within appropriately scaled blocks. Based on the idea, we develop a hierarchial process that first, a block image data with pyramid structure of input image is generated, and some candidate regions for facial regions in the block image are Quickly determined, then finally the detailed facial features; organs are decided. To find the features easily, we introduce a local gray level transform which emphasizes dark and small regions, and estimate the geometrical triangle constraints among the facial features. The merit of our method is that we can be freed from the parameter assignment problem since the algorithm utilize a simple brightness computation, consequently robust systems not being depended on specific parameter values can be easily constructed.

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Fault-Causing Process and Equipment Analysis of PCB Manufacturing Lines Using Data Mining Techniques (데이터마이닝 기법을 이용한 PCB 제조라인의 불량 혐의 공정 및 설비 분석)

  • Sim, Hyun Sik;Kim, Chang Ouk
    • KIPS Transactions on Software and Data Engineering
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    • v.4 no.2
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    • pp.65-70
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    • 2015
  • In the PCB(Printed Circuit Board) manufacturing industry, the yield is an important management factor because it affects the product cost and quality significantly. In real situation, it is very hard to ensure a high yield in a manufacturing shop because products called chips are made through hundreds of nano-scale manufacturing processes. Therefore, in order to improve the yield, it is necessary to analyze main fault process and equipment that cause low PCB yield. This paper proposes a systematic approach to discover fault-causing processes and equipment by using a logistic regression and a stepwise variable selection procedure. We tested our approach with lot trace records of real work-site. A lot trace record consists of the equipment sequence that the lot passed through and the number of faults for each fault type in the lot. We demonstrated that the test results reflected the real situation of a PCB manufacturing line.

Estimation of optimal price of freeway traffic information using a price-sensitivity analysis (가격민감도 기법을 이용한 고속도로 교통정보의 적정가치 산정 연구)

  • Lee Eui-Eun;Kim Jun-Jung
    • The Journal of The Korea Institute of Intelligent Transport Systems
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    • v.2 no.1 s.2
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    • pp.85-92
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    • 2003
  • Due to the expansion of freeway networks in Korea, drivers have more routes to choose. Traffic information on various alternative roadway sections and routes may help drivers choose the optimal route that minimizes travel time or cost. Traffic information on roadways is, therefore, invaluable in sense that individual drivers could reduce their travel time or cost by selecting optimal routes, and furthermore total travel cost of the system could be lowered. However, consensus about the price of traffic information that drivers are willing to pay is not made yet. Current price of traffic information is decided according to the price of similar information such as stock, weather and so on. To investigate the value of traffic information, a survey was conducted at freeway rest areas near Seoul Megalopolis area including Kyunggi Province. Eight hundred drivers who had travelled on freeway within a year were randomly selected. Purposive Quota Sampling was used. A price-response function, a relationship between price and sales, was obtained based on the survey, followed by sensitivity analysis

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Image Reconstruction Using Poisson Model Screened from Image Gradient (이미지 기울기에서 선별된 포아송 모델을 이용한 이미지 재구성)

  • Kim, Yong-Gil
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.18 no.2
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    • pp.117-123
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    • 2018
  • In this study, we suggest a fast image reconstruction scheme using Poisson equation from image gradient domain. In this approach, using the Poisson equation, a guided vector field is created by employing source and target images within a selected region at the first step. Next, the guided vector is used in generating the result image. We analyze the problem of reconstructing a two-dimensional function that approximates a set of desired gradients and a data term. The joined data and gradients are able to work like modifying the image gradients while staying close to the original image. Starting with this formulation, we have a screened Poisson equation known in physics. This equation leads to an efficient solution to the problem in FFT domain. It represents the spatial filters that solve the two-dimensional screened Poisson model and shows gradient scaling to be a well-defined sharpen filter that generalizes Laplace sharpening. We demonstrate the results using a discrete cosine transformation based this Poisson model.

Water Quality and Environmental Treatment Facilities

  • Kim, Geum Soo;Chang, Young Jae;Kelleher, David S.
    • Environmental and Resource Economics Review
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    • v.21 no.1
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    • pp.157-173
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    • 2012
  • It has been argued that investment in basic treatment facilities could have both a direct improvement effect and an indirect diversion effect on water quality. The reason why the investment in basic treatment facilities could have a negative diversion effect is that the investment in treatment facilities could affect a budget-constrained regulatory agency's choice in a way that would perversely encourage the regulated firms' emissions, giving a negative result in terms of water quality. We have reviewed the Korean experience and tested if the treatment facilities have improved water quality since 1991. Using a two-stage least-squares method we have shown that building treatment facilities has contributed to improving the water quality even with consideration of the negative effect through reduced enforcement effort. The model and results draw attention to the importance of optimally balancing efforts to build wastewater treatment facilities with efforts to set and enforce regulatory standards.

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